new PDB depositions vs. their blind AlphaFold predictions — a running test of "is folding solved?"

13ES_G

Coagulation factor X · P00742 · RCSB 13ES · AF-P00742-F1 (v6)

0.7781
TM-score
0.7773
lDDT
1.965
Cα-RMSD Å
88.02
mean pLDDT
0.0844
FRAUD score
100.0%
novelty (max id)

Per-domain breakdown

SourceDomainRangeResiduesTMRMSD Åmean Cα ΔName
PAEPAE:1-4881-488 440.6924 1.9651.517

All metrics

Global fold agreement

TM-score (norm. experiment)0.7781
TM-score (norm. model)0.0861
TM-score (norm. shorter)0.7781
TM-score (norm. longer)0.0861
Cα-RMSD (Å)1.965
backbone-RMSD (Å)2.038
all-atom-RMSD (Å)2.489
core-RMSD (Å)0.786
core fraction0.818
GDT_TS77.84
GDT_HA55.11
MaxSub0.7463
structural overlap (3.5 Å)0.9091

Local, superposition-free

lDDT0.7773
contact-map Jaccard0.5714
contact precision0.6667
contact recall0.8
distance-matrix mean Δ (Å)1.056
CAD-score (approx)0.8032

Backbone & secondary structure

SS agreement Q3 (%)77.27
mean Δφ (°)34.2
mean Δψ (°)40.0
torsion within 30° (frac)0.4773
Rg experiment (Å)10.48
Rg model (Å)10.13
ΔRg (Å)0.34

Confidence calibration

mean pLDDT88.02
pLDDT↔lDDT Pearson0.2594
pLDDT↔lDDT Spearman0.0215
PAE↔observed Pearson0.2866
PAE overconfident frac0.0116
mean PAE (Å)4.163
mean observed error (Å)1.032

Context & headline

coverage of model0.0902
coverage of experiment1.0
seq identity aligned (%)75.0
confidently-wrong residue frac0.0455
FRAUD score0.0844

Deposited 2026-05-03 · released 2026-07-08 · EM · 3.23 Å · closest pre-cutoff chain: 1EZQ_1