new PDB depositions vs. their blind AlphaFold predictions — a running test of "is folding solved?"

13ER_G

Prothrombin · P00734 · RCSB 13ER · AF-P00734-F1 (v6)

0.9074
TM-score
0.8883
lDDT
0.952
Cα-RMSD Å
81.76
mean pLDDT
0.0433
FRAUD score
99.4%
novelty (max id)

Per-domain breakdown

SourceDomainRangeResiduesTMRMSD Åmean Cα ΔName
PAEPAE:1-6221-622 620.9029 0.9520.828

All metrics

Global fold agreement

TM-score (norm. experiment)0.9074
TM-score (norm. model)0.0986
TM-score (norm. shorter)0.9074
TM-score (norm. longer)0.0986
Cα-RMSD (Å)0.952
backbone-RMSD (Å)0.965
all-atom-RMSD (Å)1.394
core-RMSD (Å)0.799
core fraction0.952
GDT_TS92.74
GDT_HA72.98
MaxSub0.9029
structural overlap (3.5 Å)1.0

Local, superposition-free

lDDT0.8883
contact-map Jaccard0.75
contact precision0.7692
contact recall0.9677
distance-matrix mean Δ (Å)0.525
CAD-score (approx)0.818

Backbone & secondary structure

SS agreement Q3 (%)93.55
mean Δφ (°)11.9
mean Δψ (°)15.4
torsion within 30° (frac)0.8387
Rg experiment (Å)11.48
Rg model (Å)11.36
ΔRg (Å)0.12

Confidence calibration

mean pLDDT81.76
pLDDT↔lDDT Pearson0.2249
pLDDT↔lDDT Spearman-0.1052
PAE↔observed Pearson0.3412
PAE overconfident frac0.0
mean PAE (Å)5.552
mean observed error (Å)0.516

Context & headline

coverage of model0.0997
coverage of experiment1.0
seq identity aligned (%)83.87
confidently-wrong residue frac0.0
FRAUD score0.0433

Deposited 2026-05-03 · released 2026-07-08 · EM · 3.22 Å · closest pre-cutoff chain: 6C2W_1