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New PDB Depositions vs. Their Blind AlphaFold Predictions — A Running Test of “Is Folding Solved?”

Release week 2024-12-11

302
structures analysed (14 full · 4.6%)
41.3%
confidently wrong
20.7%
novel sequences
10.3%
novel & wrong
0.913
median TM-score

Zoomed into the red "confidently wrong" box above (pLDDT ≥ 70, TM < 0.5) — the structures AlphaFold got confidently wrong.

The worst offenders ranked, one row per protein (AlphaFold has one model per sequence, so repeat depositions are collapsed — “×N” marks how many structures of that protein exist; the worst is shown). Each row joins what AlphaFold claimed (blue, pLDDT/100) to what the experiment showed (red, TM-score) — the longer the bar, the bigger the miss. Hover a dot to preview its Cα-deviation ribbon; click to open the full entry.

How to read this

Every point is one experimental protein structure. The horizontal axis is AlphaFold's own confidence in its prediction (mean pLDDT, 0–100). The vertical axis is how well that blind prediction actually matches the experiment (TM-score, 0–1; above 0.5 means the same fold, above 0.9 near-identical). Marker size grows with the FRAUD score (confidence-weighted error).

Cutoff: the shaded red box is the "confidently wrong" zone — AlphaFold was confident (mean pLDDT above 70) yet the fold is wrong (TM-score below 0.5). A predictor that had truly solved folding would leave that box empty.

Take-home: 4 of 302 structures (1.3%) are confidently wrong; median TM-score is 0.913.

Read moreShow less — how each metric is calculated

TM-score: how similar the two 3D shapes are overall, 0–1 (a random pair scores ~0.17, an identical fold ~1). Length-normalised so large and small proteins compare fairly. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) — dᵢ is the gap between the i-th aligned Cα atoms after best-fit superposition, and d₀ = 1.24(L−15)^⅓ − 1.8 sets the distance scale for length L. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264; computed with TM-align, doi:10.1093/nar/gki524.

pLDDT: AlphaFold's own confidence in each residue, 0–100 (higher = surer). It is the model predicting its own accuracy before ever seeing the experiment. We plot the per-structure mean. pLDDT = (1/N) Σᵢ pLDDTᵢ, where pLDDTᵢ is the network's confidence output for residue i.

FRAUD score: the headline number — how wrong the prediction was, weighted by how confident AlphaFold was, so a big error it was sure about counts most. FRAUD = (1/N) Σᵢ (pLDDTᵢ/100) · min(Δᵢ,15)/15, where Δᵢ is residue i's Cα distance from the experiment (Å) after superposition, capped at 15 Å. Runs 0 (perfect) to 1.

Novelty: how little AlphaFold had to go on — 100 minus the highest sequence identity between this protein and any structure released before the 2018-04-30 training cutoff. High = genuinely unseen (100% = nothing similar was ever in the training set). novelty = 100 − maxₚ identity(s, p) over pre-cutoff PDB chains p, with identity = 100 × (matching aligned residues)/(alignment length), from an MMseqs2 search.

Homology: the point colour. High novelty (above 70%) flags the sequence as novel (amber) — AlphaFold had no close template; otherwise a pre-cutoff homolog existed (blue) it could have learned the fold from. novel ⇔ novelty > 70%.

What the metrics mean

TM-score (0–1): overall fold match — above 0.5 is the same fold, above 0.9 near-identical. Cα-RMSD (Å): average backbone distance after best-fit superposition — lower is better (under 2 Å is excellent). lDDT (0–1): local accuracy measured without superposition — above 0.8 is good. Each bar counts how many structures fall in that range.

Take-home: median TM-score 0.913 — most predictions match the experimental fold well, with a long tail that do not.

Read moreShow less — how each metric is calculated

TM-score: overall shape match, 0–1 (above 0.5 = same fold, above 0.9 near-identical), length-normalised. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) with dᵢ the aligned-Cα gap after superposition and d₀ = 1.24(L−15)^⅓ − 1.8. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264.

Cα-RMSD: the average straight-line distance between matching backbone Cα atoms once the two structures are best-fit superposed (Å; lower is better, under ~2 Å excellent). RMSD = √( (1/N) Σᵢ |Pᵢ − (R·Qᵢ + t)|² ), with Pᵢ/Qᵢ the experimental/model Cα coordinates and R,t the rotation and translation from Kabsch superposition.

lDDT: local accuracy with no superposition — the fraction of short-range inter-residue distances the model reproduces, so it is not fooled by a single wrongly-placed domain. lDDT = (1/N) Σᵢ ¼ Σ_t 1[ |d_exp − d_model| < t ] over thresholds t ∈ {0.5, 1, 2, 4} Å and all residue pairs within 15 Å.

Trend over time

The blue line is the mean TM-score of the structures by their deposit month; the red bars count how many were confidently wrong. Binning by deposit date (rather than by when we processed them) gives an even timeline, tracking whether AlphaFold's accuracy on newly-deposited structures is holding steady, improving, or slipping as the PDB keeps growing. Months with fewer than 5 structures are omitted so each point is a meaningful average. A dashed trend line is drawn only if the change over time is statistically significant.

Read moreShow less — how each metric is calculated

Mean TM-score: the month's average shape-match score. TM̄ = (1/M) Σ TM over the M structures deposited that month.

Trend line: a monotonic-trend test over the monthly means — Mann-Kendall (Kendall's τ) for significance, with a robust Theil-Sen slope for the line. Rank-based, so it tolerates the skewed TM distribution and noisy low-count months. Shown only when p < 0.05; otherwise a note reports that no significant trend was found.

Confidently wrong: the count that were both confident and wrong. count( mean pLDDT > 70 AND TM < 0.5 ).

Matched structures

PDBUniProtProteinMethodÅDeposited Novelty %pLDDTTMlDDTGDT_TSRMSDFRAUDFlag
9GMW_A Q7Z7L1 Schlafen family member 11 EM 3.00 2024-08-29 44.30 89.97 0.65 0.88 8.95 21.52 0.66 ok
9ERF_A Q7Z7L1 Schlafen family member 11 EM 2.64 2024-03-22 44.30 89.97 0.65 0.88 9.16 21.42 0.65 ok
9GMX_A Q7Z7L1 Schlafen family member 11 EM 2.82 2024-08-29 44.30 89.97 0.65 0.88 9.28 21.51 0.65 ok
9ERE_A Q7Z7L1 Schlafen family member 11 EM 2.82 2024-03-22 44.30 89.97 0.65 0.87 10.13 21.27 0.64 ok
8YW2_A P98155 Very low-density lipoprotein receptor EM 3.70 2024-03-29 48.20 73.68 0.37 0.83 12.50 11.71 0.47 wrong
9GU4_A Q96P20 NACHT, LRR and PYD domains-containing prot X-ray 2.70 2024-09-18 73.00 novel 83.65 0.68 0.80 18.55 8.73 0.42 ok
8ZBL_A P34913 Bifunctional epoxide hydrolase 2 X-ray 2.70 2024-04-26 0.00 94.05 0.65 0.96 23.40 7.37 0.42 ok
8YW1_C P98155 Very low-density lipoprotein receptor EM 3.44 2024-03-29 45.80 74.14 0.38 0.88 18.18 9.48 0.39 wrong
9DQH_B A0A590UJY2 Gs-mini-Gq chimera EM 2.92 2024-09-24 85.62 0.70 0.26 ok
8VJZ_C P01116 GTPase KRas, N-terminally processed X-ray 1.90 2024-01-08 96.46 0.26 0.64 40.00 4.33 0.25 wrong
9C76_A Q5S007 Leucine-rich repeat serine/threonine-prote X-ray 2.30 2024-06-10 77.50 0.71 0.23 ok
8V1N_A P10636 Microtubule-associated protein tau EM 3.00 2023-11-20 61.71 0.17 0.49 32.35 5.61 0.21 ok
9CMP_A Q9UKV8 Protein argonaute-2 EM 3.30 2024-07-15 92.38 0.79 0.19 ok
8QYX_V1 P47914 60S ribosomal protein L29 EM 1.78 2023-10-26 81.44 0.78 0.18 ok
8YIC_A P63096 Guanine nucleotide-binding protein G(i) su EM 3.47 2024-02-29 93.75 0.81 0.18 ok
9K1C_A P63096 Guanine nucleotide-binding protein G(i) su EM 3.20 2024-10-16 93.75 0.81 0.18 ok
9K1D_A P63096 Guanine nucleotide-binding protein G(i) su EM 3.34 2024-10-16 93.75 0.81 0.17 ok
8YVZ_E P98155 Very low-density lipoprotein receptor EM 3.45 2024-03-29 75.69 0.77 0.17 ok
9AST_A P63096 Guanine nucleotide-binding protein G(i) su EM 3.07 2024-02-26 93.75 0.82 0.16 ok
9BEE_A P02511 Alpha-crystallin B chain EM 3.40 2024-04-15 75.75 0.80 0.15 ok
9EGV_A Q9BYM8 RanBP-type and C3HC4-type zinc finger-cont X-ray 2.00 2024-11-21 84.00 0.83 0.15 ok
8YIC_C P59768 Guanine nucleotide-binding protein G(I)/G( EM 3.47 2024-02-29 89.56 0.84 0.15 ok
9EGW_A Q9BYM8 RanBP-type and C3HC4-type zinc finger-cont X-ray 1.78 2024-11-21 84.00 0.83 0.14 ok
7GYF_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 1.92 2024-01-12 88.88 0.85 0.13 ok
7GYH_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 1.92 2024-01-12 88.88 0.85 0.13 ok
7GYI_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 1.92 2024-01-12 88.88 0.85 0.13 ok
7GYG_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 1.92 2024-01-12 88.88 0.85 0.13 ok
7GYD_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 1.92 2024-01-12 88.88 0.85 0.13 ok
7GYE_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 1.92 2024-01-12 88.88 0.85 0.13 ok
7GYB_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 1.92 2024-01-12 88.88 0.85 0.13 ok
7GYC_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 1.92 2024-01-12 88.88 0.85 0.13 ok
7GYA_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 1.92 2024-01-12 88.88 0.85 0.13 ok
7GY9_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 1.92 2024-01-12 88.88 0.85 0.13 ok
7GY7_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 1.92 2024-01-12 88.88 0.85 0.13 ok
7GY8_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 1.92 2024-01-12 88.88 0.85 0.13 ok
7GY6_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 1.92 2024-01-12 88.88 0.85 0.13 ok
7GY5_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 1.92 2024-01-12 88.88 0.85 0.13 ok
7GY4_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 1.92 2024-01-12 88.88 0.85 0.13 ok
9GY8_B Q15596 Nuclear receptor coactivator 2 X-ray 2.20 2024-10-01 47.59 0.73 0.13 ok
9BEE_B P02511 Alpha-crystallin B chain EM 3.40 2024-04-15 75.75 0.83 0.13 ok
7GYX_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 2.15 2024-01-12 88.88 0.86 0.12 ok
7GYV_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 2.15 2024-01-12 88.88 0.86 0.12 ok
7GYT_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 2.15 2024-01-12 88.88 0.86 0.12 ok
7GYW_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 2.15 2024-01-12 88.88 0.86 0.12 ok
7GYU_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 2.15 2024-01-12 88.88 0.86 0.12 ok
7GYS_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 2.15 2024-01-12 88.88 0.86 0.12 ok
7GYR_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 2.15 2024-01-12 88.88 0.86 0.12 ok
7GYQ_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 2.15 2024-01-12 88.88 0.86 0.12 ok
7GYP_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 2.15 2024-01-12 88.88 0.86 0.12 ok
7GYO_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 2.15 2024-01-12 88.88 0.86 0.12 ok
7GYN_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 2.15 2024-01-12 88.88 0.86 0.12 ok
7GYM_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 2.15 2024-01-12 88.88 0.86 0.12 ok
9K1C_C P59768 Guanine nucleotide-binding protein G(I)/G( EM 3.20 2024-10-16 89.56 0.86 0.12 ok
7GYL_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 2.15 2024-01-12 88.88 0.86 0.12 ok
7GYK_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 2.15 2024-01-12 88.88 0.86 0.12 ok
7GYJ_A P0DMV8 Heat shock 70 kDa protein 1A X-ray 2.15 2024-01-12 88.88 0.86 0.12 ok
8JQH_A P16885 1-phosphatidylinositol 4,5-bisphosphate ph EM 4.20 2023-06-14 83.38 0.86 0.11 ok
8S7D_C P63208 S-phase kinase-associated protein 1 EM 3.20 2024-02-29 90.12 0.88 0.11 ok
9GYA_B Q15596 Nuclear receptor coactivator 2 X-ray 1.85 2024-10-01 47.59 0.78 0.11 ok
9GYJ_B Q15596 Nuclear receptor coactivator 2 X-ray 1.90 2024-10-02 47.59 0.78 0.11 ok
8QYX_d1 P61927 60S ribosomal protein L37 EM 1.78 2023-10-26 89.50 0.88 0.10 ok
9AST_L P47992 Lymphotactin EM 3.07 2024-02-26 0.00 67.05 0.39 0.73 63.64 2.51 0.10 ok
9AST_G P59768 Guanine nucleotide-binding protein G(I)/G( EM 3.07 2024-02-26 89.56 0.89 0.10 ok
9K1D_C P59768 Guanine nucleotide-binding protein G(I)/G( EM 3.34 2024-10-16 89.56 0.89 0.10 ok
8S7E_A P63208 S-phase kinase-associated protein 1 EM 3.40 2024-02-29 90.12 0.90 0.09 ok
8QYX_a1 P49207 60S ribosomal protein L34 EM 1.78 2023-10-26 90.38 0.91 0.09 ok
9GYC_B Q15596 Nuclear receptor coactivator 2 X-ray 2.20 2024-10-01 47.59 0.82 0.09 ok
9ETY_A Q14145 Kelch-like ECH-associated protein 1 X-ray 1.87 2024-03-27 90.06 0.91 0.08 ok
8QYX_U1 P46776 Large ribosomal subunit protein uL15 EM 1.78 2023-10-26 93.75 0.91 0.08 ok
8UKO_C Q13936 ARG-GLY-PHE-LEU-ARG-SER-ALA-SER-LEU-GLY-AR X-ray 2.89 2023-10-14 26.15 0.33 0.53 39.71 4.91 0.08 ok
8QYX_f1 P62891 60S ribosomal protein L39 EM 1.78 2023-10-26 94.00 0.92 0.07 ok
8VSZ_A O00591 Gamma-aminobutyric acid receptor subunit p EM 3.07 2024-01-25 79.12 0.91 0.07 ok
9GYK_B Q15596 Nuclear receptor coactivator 2 X-ray 2.20 2024-10-02 47.59 0.85 0.07 ok
8UKP_C Q13936 ARG-GLY-PHE-LEU-ARG-SER-ALA-SER-LEU-GLY-AR X-ray 2.85 2023-10-14 26.04 0.28 0.54 39.06 4.31 0.07 ok
9ETX_A Q14145 Kelch-like ECH-associated protein 1 X-ray 2.34 2024-03-27 90.06 0.93 0.07 ok
9K1C_R O14842 Free fatty acid receptor 1 EM 3.20 2024-10-16 89.75 0.93 0.07 ok
8JQI_B P11362 Fibroblast growth factor receptor 1 EM 4.10 2023-06-14 73.88 0.91 0.07 ok
8V64_A Q12791 Calcium-activated potassium channel subuni EM 2.60 2023-12-01 76.00 0.91 0.06 ok
8V60_A Q12791 Calcium-activated potassium channel subuni EM 2.43 2023-12-01 76.00 0.92 0.06 ok
8VTI_A Q9HAR2 Isoform 4 of Adhesion G protein-coupled re EM 3.90 2024-01-26 69.38 0.92 0.06 ok
8V63_A Q12791 Calcium-activated potassium channel subuni EM 2.72 2023-12-01 76.00 0.93 0.06 ok
9CGP_E P68106 Peptidyl-prolyl cis-trans isomerase FKBP1B EM 3.34 2024-06-30 94.88 0.94 0.05 ok
9JEJ_A Q09472 Histone acetyltransferase p300 X-ray 2.90 2024-09-03 53.25 0.90 0.05 ok
9DQJ_A Q8TDS7 Mas-related G-protein coupled receptor mem EM 2.90 2024-09-24 85.44 0.94 0.05 ok
9DQH_D P59768 Guanine nucleotide-binding protein G(I)/G( EM 2.92 2024-09-24 89.56 0.94 0.05 ok
9DQH_A Q8TDS7 Mas-related G-protein coupled receptor mem EM 2.92 2024-09-24 85.44 0.94 0.05 ok
9GRA_A O14867 Transcription regulator protein BACH1 X-ray 1.47 2024-09-11 56.47 0.91 0.05 ok
7GVB_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GV7_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GVL_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GVJ_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GVH_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GVF_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GVD_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GVA_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GV9_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GV8_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GVE_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GVC_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GVI_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GVG_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GW5_A P41182 B-cell lymphoma 6 protein X-ray 1.75 2024-01-09 52.06 0.91 0.05 ok
7GW1_A P41182 B-cell lymphoma 6 protein X-ray 1.75 2024-01-09 52.06 0.91 0.05 ok
7GVK_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GW3_A P41182 B-cell lymphoma 6 protein X-ray 1.75 2024-01-09 52.06 0.91 0.05 ok
7GW9_A P41182 B-cell lymphoma 6 protein X-ray 1.75 2024-01-09 52.06 0.91 0.05 ok
7GW4_A P41182 B-cell lymphoma 6 protein X-ray 1.75 2024-01-09 52.06 0.91 0.05 ok
7GW2_A P41182 B-cell lymphoma 6 protein X-ray 1.75 2024-01-09 52.06 0.91 0.05 ok
7GWZ_A P41182 B-cell lymphoma 6 protein X-ray 1.70 2024-01-09 52.06 0.91 0.05 ok
7GWY_A P41182 B-cell lymphoma 6 protein X-ray 1.70 2024-01-09 52.06 0.91 0.05 ok
7GWX_A P41182 B-cell lymphoma 6 protein X-ray 1.70 2024-01-09 52.06 0.91 0.05 ok
7GWV_A P41182 B-cell lymphoma 6 protein X-ray 1.70 2024-01-09 52.06 0.91 0.05 ok
7GW7_A P41182 B-cell lymphoma 6 protein X-ray 1.75 2024-01-09 52.06 0.91 0.05 ok
7GW6_A P41182 B-cell lymphoma 6 protein X-ray 1.75 2024-01-09 52.06 0.91 0.05 ok
7GX8_A P41182 B-cell lymphoma 6 protein X-ray 1.70 2024-01-09 52.06 0.91 0.05 ok
7GX7_A P41182 B-cell lymphoma 6 protein X-ray 1.70 2024-01-09 52.06 0.91 0.05 ok
7GX6_A P41182 B-cell lymphoma 6 protein X-ray 1.70 2024-01-09 52.06 0.91 0.05 ok
7GX4_A P41182 B-cell lymphoma 6 protein X-ray 1.70 2024-01-09 52.06 0.91 0.05 ok
7GX3_A P41182 B-cell lymphoma 6 protein X-ray 1.70 2024-01-09 52.06 0.91 0.05 ok
7GX2_A P41182 B-cell lymphoma 6 protein X-ray 1.70 2024-01-09 52.06 0.91 0.05 ok
7GX1_A P41182 B-cell lymphoma 6 protein X-ray 1.70 2024-01-09 52.06 0.91 0.05 ok
7GX0_A P41182 B-cell lymphoma 6 protein X-ray 1.70 2024-01-09 52.06 0.91 0.05 ok
7GWW_A P41182 B-cell lymphoma 6 protein X-ray 1.70 2024-01-09 52.06 0.91 0.05 ok
7GWD_A P41182 B-cell lymphoma 6 protein X-ray 1.75 2024-01-09 52.06 0.91 0.05 ok
7GWB_A P41182 B-cell lymphoma 6 protein X-ray 1.75 2024-01-09 52.06 0.91 0.05 ok
7GW8_A P41182 B-cell lymphoma 6 protein X-ray 1.75 2024-01-09 52.06 0.91 0.05 ok
7GX9_A P41182 B-cell lymphoma 6 protein X-ray 1.70 2024-01-09 52.06 0.91 0.05 ok
7GX5_A P41182 B-cell lymphoma 6 protein X-ray 1.70 2024-01-09 52.06 0.91 0.05 ok
7GWA_A P41182 B-cell lymphoma 6 protein X-ray 1.75 2024-01-09 52.06 0.91 0.05 ok
7GWF_A P41182 B-cell lymphoma 6 protein X-ray 1.75 2024-01-09 52.06 0.91 0.05 ok
7GWE_A P41182 B-cell lymphoma 6 protein X-ray 1.75 2024-01-09 52.06 0.91 0.05 ok
7GWC_A P41182 B-cell lymphoma 6 protein X-ray 1.75 2024-01-09 52.06 0.91 0.05 ok
7GWP_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.91 0.05 ok
7GWT_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.91 0.05 ok
7GWN_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.91 0.05 ok
7GWL_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.91 0.05 ok
7GWJ_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.91 0.05 ok
7GWH_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.91 0.05 ok
7GWR_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.91 0.05 ok
7GWI_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.91 0.05 ok
7GWG_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.91 0.05 ok
7GWM_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.91 0.05 ok
7GWK_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.91 0.05 ok
7GWU_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.91 0.05 ok
7GWO_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.91 0.05 ok
7GWS_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.91 0.05 ok
7GWQ_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.91 0.05 ok
9K1D_R O15552 Free fatty acid receptor 2 EM 3.34 2024-10-16 88.06 0.95 0.05 ok
7GXT_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GXP_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GXF_A P41182 B-cell lymphoma 6 protein X-ray 1.95 2024-01-09 52.06 0.91 0.05 ok
7GXD_A P41182 B-cell lymphoma 6 protein X-ray 1.95 2024-01-09 52.06 0.91 0.05 ok
7GXB_A P41182 B-cell lymphoma 6 protein X-ray 1.95 2024-01-09 52.06 0.91 0.05 ok
7GXA_A P41182 B-cell lymphoma 6 protein X-ray 1.95 2024-01-09 52.06 0.91 0.05 ok
7GXX_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GXV_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GXR_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GXQ_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GXJ_A P41182 B-cell lymphoma 6 protein X-ray 1.95 2024-01-09 52.06 0.91 0.05 ok
7GXE_A P41182 B-cell lymphoma 6 protein X-ray 1.95 2024-01-09 52.06 0.91 0.05 ok
7GXC_A P41182 B-cell lymphoma 6 protein X-ray 1.95 2024-01-09 52.06 0.91 0.05 ok
9EGV_C P0CG48 Polyubiquitin-C X-ray 2.00 2024-11-21 88.62 0.95 0.05 ok
7GY3_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GY1_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GXZ_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GXU_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GXS_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GXO_A P41182 B-cell lymphoma 6 protein X-ray 1.95 2024-01-09 52.06 0.91 0.05 ok
7GXL_A P41182 B-cell lymphoma 6 protein X-ray 1.95 2024-01-09 52.06 0.91 0.05 ok
7GXK_A P41182 B-cell lymphoma 6 protein X-ray 1.95 2024-01-09 52.06 0.91 0.05 ok
7GXI_A P41182 B-cell lymphoma 6 protein X-ray 1.95 2024-01-09 52.06 0.91 0.05 ok
7GXH_A P41182 B-cell lymphoma 6 protein X-ray 1.95 2024-01-09 52.06 0.91 0.05 ok
7GXG_A P41182 B-cell lymphoma 6 protein X-ray 1.95 2024-01-09 52.06 0.91 0.05 ok
7GXY_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GXW_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.05 ok
7GXN_A P41182 B-cell lymphoma 6 protein X-ray 1.95 2024-01-09 52.06 0.91 0.05 ok
7GXM_A P41182 B-cell lymphoma 6 protein X-ray 1.95 2024-01-09 52.06 0.91 0.05 ok
7GY2_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.04 ok
7GY0_A P41182 B-cell lymphoma 6 protein X-ray 1.85 2024-01-09 52.06 0.91 0.04 ok
9EGW_C P0CG48 Polyubiquitin-C X-ray 1.78 2024-11-21 88.62 0.95 0.04 ok
7GVP_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.92 0.04 ok
7GVN_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.92 0.04 ok
7GVX_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.92 0.04 ok
7GVR_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.92 0.04 ok
7GW0_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.92 0.04 ok
7GVZ_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.92 0.04 ok
7GVV_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.92 0.04 ok
7GVU_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.92 0.04 ok
7GVT_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.92 0.04 ok
7GVS_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.92 0.04 ok
7GVO_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.92 0.04 ok
7GVM_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.92 0.04 ok
7GVY_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.92 0.04 ok
7GVQ_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.92 0.04 ok
7GVW_A P41182 B-cell lymphoma 6 protein X-ray 1.90 2024-01-09 52.06 0.92 0.04 ok
9CGQ_E P68106 Peptidyl-prolyl cis-trans isomerase FKBP1B EM 3.23 2024-06-30 94.88 0.96 0.04 ok
8QYX_J1 P18621 60S ribosomal protein L17 EM 1.78 2023-10-26 91.88 0.95 0.04 ok
8QYX_b1 P42766 60S ribosomal protein L35 EM 1.78 2023-10-26 94.56 0.96 0.04 ok
8QYX_A1 P18124 Large ribosomal subunit protein uL30 EM 1.78 2023-10-26 93.94 0.96 0.04 ok
9DQJ_D P59768 Guanine nucleotide-binding protein G(I)/G( EM 2.90 2024-09-24 89.56 0.96 0.04 ok
9D7Q_A Q9BYP7 Serine/threonine-protein kinase WNK3 X-ray 3.30 2024-08-16 47.41 0.93 0.03 ok
8Z03_B Q96I99 Succinate--CoA ligase [GDP-forming] subuni X-ray 1.99 2024-04-08 89.25 0.96 0.03 ok
8VTI_B Q9HAR2 Isoform 4 of Adhesion G protein-coupled re EM 3.90 2024-01-26 70.50 novel 78.27 0.45 0.96 93.18 0.82 0.03 wrong
8QYX_j1 P61513 60S ribosomal protein L37a EM 1.78 2023-10-26 96.31 0.96 0.03 ok
8QYX_N1 P46778 60S ribosomal protein L21 EM 1.78 2023-10-26 94.06 0.96 0.03 ok
9HK0_A Q9Y603 Transcription factor ETV7 X-ray 1.61 2024-12-02 64.81 0.95 0.03 ok
8QYX_O1 P35268 60S ribosomal protein L22 EM 1.78 2023-10-26 83.94 0.96 0.03 ok
8QYX_c1 Q9Y3U8 60S ribosomal protein L36 EM 1.78 2023-10-26 93.12 0.97 0.03 ok
8QYX_B1 P62424 60S ribosomal protein L7a EM 1.78 2023-10-26 90.62 0.97 0.03 ok
8QYX_g1 P62987 Large ribosomal subunit protein eL40 EM 1.78 2023-10-26 93.50 0.97 0.03 ok
8VV0_A O00591 Gamma-aminobutyric acid receptor subunit p EM 3.10 2024-01-30 79.12 0.96 0.03 ok
9KKU_A P15692 Vascular endothelial growth factor A, long X-ray 1.46 2024-11-14 63.91 0.95 0.03 ok
8S7E_B Q8NEZ5 F-box only protein 22 EM 3.40 2024-02-29 86.25 0.97 0.03 ok
8VJZ_A P04439 HLA class I histocompatibility antigen, A X-ray 1.90 2024-01-08 87.12 0.97 0.03 ok
8QYX_L1 P84098 60S ribosomal protein L19 EM 1.78 2023-10-26 94.75 0.97 0.03 ok
8QYX_R1 P62750 60S ribosomal protein L23a EM 1.78 2023-10-26 89.31 0.97 0.03 ok
9GR9_A O14867 Transcription regulator protein BACH1 X-ray 2.25 2024-09-11 56.47 0.95 0.03 ok
9ETW_A Q53HC5 Kelch-like protein 26 X-ray 1.51 2024-03-27 91.31 0.97 0.03 ok
9AV9_A P69905 Hemoglobin subunit alpha X-ray 1.94 2024-03-01 98.06 0.97 0.03 ok
8Z03_A P53597 Succinate--CoA ligase [ADP/GDP-forming] su X-ray 1.99 2024-04-08 91.44 0.97 0.03 ok
9ERD_A Q7Z7L1 Schlafen family member 11 EM 3.72 2024-03-22 86.62 0.97 0.03 ok
8QYX_X1 P62899 60S ribosomal protein L31 EM 1.78 2023-10-26 87.94 0.97 0.03 ok
8JQI_A P16885 1-phosphatidylinositol 4,5-bisphosphate ph EM 4.10 2023-06-14 83.38 0.97 0.03 ok
8QYX_G2 P46777 60S ribosomal protein L5 EM 1.78 2023-10-26 94.50 0.97 0.02 ok
8QYX_e1 P63173 60S ribosomal protein L38 EM 1.78 2023-10-26 95.38 0.97 0.02 ok
8QYX_F1 P26373 60S ribosomal protein L13 EM 1.78 2023-10-26 95.38 0.97 0.02 ok
8JQG_A P16885 1-phosphatidylinositol 4,5-bisphosphate ph EM 3.72 2023-06-14 83.38 0.97 0.02 ok
8VZG_A P00918 Carbonic anhydrase 2 X-ray 1.79 2024-02-11 97.38 0.98 0.02 ok
8QYX_Y1 P62910 60S ribosomal protein L32 EM 1.78 2023-10-26 92.38 0.98 0.02 ok
8Z02_B Q96I99 Succinate--CoA ligase [GDP-forming] subuni X-ray 2.32 2024-04-08 89.25 0.97 0.02 ok
8YW0_E P98155 Very low-density lipoprotein receptor EM 3.55 2024-03-29 75.69 0.97 0.02 ok
8Z02_A P53597 Succinate--CoA ligase [ADP/GDP-forming] su X-ray 2.32 2024-04-08 91.44 0.98 0.02 ok
8S7D_A O14867 Transcription regulator protein BACH1 EM 3.20 2024-02-29 56.47 0.96 0.02 ok
8QYX_Q1 P83731 60S ribosomal protein L24 EM 1.78 2023-10-26 80.50 0.97 0.02 ok
8S7D_D Q8NEZ5 F-box only protein 22 EM 3.20 2024-02-29 86.25 0.98 0.02 ok
8QYX_P1 P62829 60S ribosomal protein L23 EM 1.78 2023-10-26 92.62 0.98 0.02 ok
8QYX_i1 P83881 60S ribosomal protein L36a EM 1.78 2023-10-26 94.31 0.98 0.02 ok
9ASG_A P04439 HLA class I histocompatibility antigen, A X-ray 2.03 2024-02-25 87.12 0.98 0.02 ok
9EEY_A P54829 Tyrosine-protein phosphatase non-receptor X-ray 1.75 2024-11-19 72.06 0.97 0.02 ok
9ASF_A P04439 HLA class I histocompatibility antigen, A X-ray 1.77 2024-02-25 87.12 0.98 0.02 ok
8QYX_H2 Q02878 60S ribosomal protein L6 EM 1.78 2023-10-26 82.81 0.98 0.02 ok
8QYX_F2 P36578 60S ribosomal protein L4 EM 1.78 2023-10-26 87.12 0.98 0.02 ok
8XB1_A P36888 Receptor-type tyrosine-protein kinase FLT3 X-ray 2.85 2023-12-05 75.94 0.97 0.02 ok
8VCL_A P04439 HLA class I histocompatibility antigen, A X-ray 2.40 2023-12-14 87.12 0.98 0.02 ok
8YIC_B P62873 Guanine nucleotide-binding protein G(I)/G( EM 3.47 2024-02-29 97.06 0.98 0.02 ok
8QYX_D1 Q96L21 Ribosomal protein uL16-like EM 1.78 2023-10-26 94.75 0.98 0.02 ok
9GP5_C O14867 Transcription regulator protein BACH1 X-ray 1.90 2024-09-06 56.47 0.97 0.02 ok
9EEX_A P54829 Tyrosine-protein phosphatase non-receptor X-ray 1.27 2024-11-19 72.06 0.98 0.02 ok
9AV9_B P68871 Hemoglobin subunit beta X-ray 1.94 2024-03-01 97.19 0.98 0.02 ok
8VCL_B P61769 Beta-2-microglobulin X-ray 2.40 2023-12-14 94.06 0.98 0.02 ok
8ZMB_A O60885 BRD4_HUMAN X-ray 2.79 2024-05-22 55.31 0.97 0.02 ok
9EEZ_A P54829 Tyrosine-protein phosphatase non-receptor X-ray 1.60 2024-11-19 72.06 0.98 0.01 ok
9FY5_A Q99685 Monoglyceride lipase X-ray 1.43 2024-07-02 93.88 0.98 0.01 ok
8QYX_G1 P50914 60S ribosomal protein L14 EM 1.78 2023-10-26 76.56 0.98 0.01 ok
8RBH_A Q53G59 Kelch-like protein 12 X-ray 1.88 2023-12-04 93.31 0.99 0.01 ok
8QYX_S1 P61254 60S ribosomal protein L26 EM 1.78 2023-10-26 92.88 0.99 0.01 ok
8ZM8_A O60885 BRD4_HUMAN X-ray 3.00 2024-05-22 55.31 0.98 0.01 ok
8Z69_A P25440 BRD2_HUMAN X-ray 1.77 2024-04-18 64.06 0.98 0.01 ok
8QYX_E1 P62913 60S ribosomal protein L11 EM 1.78 2023-10-26 91.56 0.99 0.01 ok
8ZMQ_A O60885 BRD4_HUMAN X-ray 2.20 2024-05-23 55.31 0.98 0.01 ok
9AYZ_B P68871 Hemoglobin subunit beta X-ray 2.24 2024-03-09 97.19 0.99 0.01 ok
8WZS_A Q9UGM3 Deleted in malignant brain tumors 1 protei X-ray 2.54 2023-11-02 73.75 0.98 0.01 ok
9ASF_B P61769 Beta-2-microglobulin X-ray 1.77 2024-02-25 94.06 0.99 0.01 ok
8QYX_I1 P40429 60S ribosomal protein L13a EM 1.78 2023-10-26 95.75 0.99 0.01 ok
8QYX_C1 P32969 60S ribosomal protein L9 EM 1.78 2023-10-26 94.12 0.99 0.01 ok
8QYX_K1 Q07020 60S ribosomal protein L18 EM 1.78 2023-10-26 95.50 0.99 0.01 ok
8V72_A Q8NFU5 Inositol polyphosphate multikinase X-ray 2.00 2023-12-04 73.75 0.98 0.01 ok
9ASG_B P61769 Beta-2-microglobulin X-ray 2.03 2024-02-25 94.06 0.99 0.01 ok
8VJZ_B P61769 Beta-2-microglobulin X-ray 1.90 2024-01-08 94.06 0.99 0.01 ok
8QYX_W1 P62888 60S ribosomal protein L30 EM 1.78 2023-10-26 88.00 0.99 0.01 ok
8V70_A Q8NFU5 Inositol polyphosphate multikinase X-ray 1.85 2023-12-04 73.75 0.99 0.01 ok
8QYX_k1 P46779 60S ribosomal protein L28 EM 1.78 2023-10-26 92.69 0.99 0.01 ok
8QYX_T1 P61353 60S ribosomal protein L27 EM 1.78 2023-10-26 94.31 0.99 0.01 ok
8V6Z_A Q8NFU5 Inositol polyphosphate multikinase X-ray 1.85 2023-12-04 73.75 0.99 0.01 ok
8V6X_A Q8NFU5 Inositol polyphosphate multikinase X-ray 1.75 2023-12-04 73.75 0.99 0.01 ok
9K1D_B P62873 Guanine nucleotide-binding protein G(I)/G( EM 3.34 2024-10-16 97.06 0.99 0.01 ok
8V74_A Q8NFU5 Inositol polyphosphate multikinase X-ray 1.85 2023-12-04 73.75 0.99 0.01 ok
8QYX_Z1 P18077 60S ribosomal protein L35a EM 1.78 2023-10-26 95.56 0.99 0.01 ok
9K1C_B P62873 Guanine nucleotide-binding protein G(I)/G( EM 3.20 2024-10-16 97.06 0.99 0.01 ok
8V79_A Q8NFU5 Inositol polyphosphate multikinase X-ray 1.95 2023-12-04 73.75 0.99 0.01 ok
8V75_A Q8NFU5 Inositol polyphosphate multikinase X-ray 1.85 2023-12-04 73.75 0.99 0.01 ok
8QYX_H1 P61313 60S ribosomal protein L15 EM 1.78 2023-10-26 96.19 0.99 0.01 ok
8QYX_M1 Q02543 60S ribosomal protein L18a EM 1.78 2023-10-26 96.31 0.99 0.01 ok
8V77_A Q8NFU5 Inositol polyphosphate multikinase X-ray 1.95 2023-12-04 73.75 0.99 0.01 ok
8V78_A Q8NFU5 Inositol polyphosphate multikinase X-ray 1.96 2023-12-04 73.75 0.99 0.01 ok
8V76_A Q8NFU5 Inositol polyphosphate multikinase X-ray 1.90 2023-12-04 73.75 0.99 0.01 ok
8V73_A Q8NFU5 Inositol polyphosphate multikinase X-ray 1.90 2023-12-04 73.75 0.99 0.01 ok
8V6W_A Q8NFU5 Inositol polyphosphate multikinase X-ray 1.95 2023-12-04 73.75 0.99 0.01 ok
8QYX_E2 P39023 Large ribosomal subunit protein uL3 EM 1.78 2023-10-26 96.38 0.99 0.01 ok
8QYX_D2 P62917 Large ribosomal subunit protein uL2 EM 1.78 2023-10-26 95.31 0.99 0.01 ok
8V71_A Q8NFU5 Inositol polyphosphate multikinase X-ray 1.70 2023-12-04 73.75 0.99 0.01 ok
8VIY_A O15296 Polyunsaturated fatty acid lipoxygenase AL X-ray 2.34 2024-01-05 95.19 0.99 0.01 ok
8V9D_A P55087 Aquaporin-4 EM 2.90 2023-12-07 81.06 0.99 0.01 ok
8V6Y_A Q8NFU5 Inositol polyphosphate multikinase X-ray 1.70 2023-12-04 73.75 0.99 0.01 ok
9AYZ_A P69905 Hemoglobin subunit alpha X-ray 2.24 2024-03-09 98.06 0.99 0.01 ok
9AST_B P62873 Guanine nucleotide-binding protein G(I)/G( EM 3.07 2024-02-26 97.06 0.99 0.00 ok
8VV8_A Q96KQ7 Histone-lysine N-methyltransferase EHMT2 X-ray 2.00 2024-01-30 68.31 0.99 0.00 ok
8V91_A P55087 Aquaporin-4 EM 2.60 2023-12-07 81.06 0.99 0.00 ok
9DQH_C P62873 Guanine nucleotide-binding protein G(I)/G( EM 2.92 2024-09-24 97.06 1.00 0.00 ok
8V8S_A P55087 Aquaporin-4 EM 2.20 2023-12-06 81.06 1.00 0.00 ok
9DQJ_C P62873 Guanine nucleotide-binding protein G(I)/G( EM 2.90 2024-09-24 97.06 1.00 0.00 ok
8XWB_A P02794 Ferritin heavy chain X-ray 1.69 2024-01-16 95.31 1.00 0.00 ok

Click a column header to sort. FRAUD = confidence-weighted error; a structure is flagged confidently wrong when mean pLDDT > 70 yet TM-score < 0.5.