Release week 2024-10-23

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204

structures analysed (17 full · 8.3%)

21.0%

confidently wrong

42.0%

novel sequences

00.0%

novel & wrong

0.949

median TM-score

⭐ This week's notable releases

4 novel sequences, 2 confidently wrong. Highlight: Isoform 2 of HBS1-like protein.

PDB	Protein	Flags	Why it matters
9G8M_E ↗	Isoform 2 of HBS1-like protein	novel · 100%	Genuinely unseen sequence (0% identity to anything AlphaFold trained on).
8TM6_e ↗	Proteasome maturation protein	novel · 100%	Genuinely unseen sequence (0% identity to anything AlphaFold trained on).
8TM5_e ↗	Proteasome maturation protein	novel · 100%	Genuinely unseen sequence (0% identity to anything AlphaFold trained on).
8TM4_e ↗	Proteasome maturation protein	novel · 100%	Genuinely unseen sequence (0% identity to anything AlphaFold trained on).
9G8M_Sf ↗	Ubiquitin	confidently wrong	A close pre-cutoff homolog existed (100% identity to 3J7P_81) yet AlphaFold confidently missed the fold.
9JKB_R ↗	E3 ubiquitin-protein ligase RBX1, N-terminally p	confidently wrong	A close pre-cutoff homolog existed (97% identity to 1U6G_2) yet AlphaFold confidently missed the fold.

see all 204 structures ↓

Zoomed into the red "confidently wrong" box above (pLDDT ≥ 70, TM < 0.5) — the structures AlphaFold got confidently wrong.

The worst offenders ranked, one row per protein (AlphaFold has one model per sequence, so repeat depositions are collapsed — “×N” marks how many structures of that protein exist; the worst is shown). Each row joins what AlphaFold claimed (blue, pLDDT/100) to what the experiment showed (red, TM-score) — the longer the bar, the bigger the miss. Hover a dot to preview its Cα-deviation ribbon; click to open the full entry.

How to read this

Every point is one experimental protein structure. The horizontal axis is AlphaFold's own confidence in its prediction (mean pLDDT, 0–100). The vertical axis is how well that blind prediction actually matches the experiment (TM-score, 0–1; above 0.5 means the same fold, above 0.9 near-identical). Marker size grows with the FRAUD score (confidence-weighted error).

Cutoff: the shaded red box is the "confidently wrong" zone — AlphaFold was confident (mean pLDDT above 70) yet the fold is wrong (TM-score below 0.5). A predictor that had truly solved folding would leave that box empty.

Take-home: 2 of 204 structures (1.0%) are confidently wrong; median TM-score is 0.949.

Read moreShow less — how each metric is calculated

TM-score: how similar the two 3D shapes are overall, 0–1 (a random pair scores ~0.17, an identical fold ~1). Length-normalised so large and small proteins compare fairly. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) — dᵢ is the gap between the i-th aligned Cα atoms after best-fit superposition, and d₀ = 1.24(L−15)^⅓ − 1.8 sets the distance scale for length L. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264; computed with TM-align, doi:10.1093/nar/gki524.

pLDDT: AlphaFold's own confidence in each residue, 0–100 (higher = surer). It is the model predicting its own accuracy before ever seeing the experiment. We plot the per-structure mean. pLDDT = (1/N) Σᵢ pLDDTᵢ, where pLDDTᵢ is the network's confidence output for residue i.

FRAUD score: the headline number — how wrong the prediction was, weighted by how confident AlphaFold was, so a big error it was sure about counts most. FRAUD = (1/N) Σᵢ (pLDDTᵢ/100) · min(Δᵢ,15)/15, where Δᵢ is residue i's Cα distance from the experiment (Å) after superposition, capped at 15 Å. Runs 0 (perfect) to 1.

Novelty: how little AlphaFold had to go on — 100 minus the highest sequence identity between this protein and any structure released before the 2018-04-30 training cutoff. High = genuinely unseen (100% = nothing similar was ever in the training set). novelty = 100 − maxₚ identity(s, p) over pre-cutoff PDB chains p, with identity = 100 × (matching aligned residues)/(alignment length), from an MMseqs2 search.

Homology: the point colour. High novelty (above 70%) flags the sequence as novel (amber) — AlphaFold had no close template; otherwise a pre-cutoff homolog existed (blue) it could have learned the fold from. novel ⇔ novelty > 70%.

What the metrics mean

TM-score (0–1): overall fold match — above 0.5 is the same fold, above 0.9 near-identical. Cα-RMSD (Å): average backbone distance after best-fit superposition — lower is better (under 2 Å is excellent). lDDT (0–1): local accuracy measured without superposition — above 0.8 is good. Each bar counts how many structures fall in that range.

Take-home: median TM-score 0.949 — most predictions match the experimental fold well, with a long tail that do not.

Read moreShow less — how each metric is calculated

TM-score: overall shape match, 0–1 (above 0.5 = same fold, above 0.9 near-identical), length-normalised. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) with dᵢ the aligned-Cα gap after superposition and d₀ = 1.24(L−15)^⅓ − 1.8. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264.

Cα-RMSD: the average straight-line distance between matching backbone Cα atoms once the two structures are best-fit superposed (Å; lower is better, under ~2 Å excellent). RMSD = √( (1/N) Σᵢ |Pᵢ − (R·Qᵢ + t)|² ), with Pᵢ/Qᵢ the experimental/model Cα coordinates and R,t the rotation and translation from Kabsch superposition.

lDDT: local accuracy with no superposition — the fraction of short-range inter-residue distances the model reproduces, so it is not fooled by a single wrongly-placed domain. lDDT = (1/N) Σᵢ ¼ Σ_t 1[ |d_exp − d_model| < t ] over thresholds t ∈ {0.5, 1, 2, 4} Å and all residue pairs within 15 Å.

Trend over time

The blue line is the mean TM-score of the structures by their deposit month; the red bars count how many were confidently wrong. Binning by deposit date (rather than by when we processed them) gives an even timeline, tracking whether AlphaFold's accuracy on newly-deposited structures is holding steady, improving, or slipping as the PDB keeps growing. Months with fewer than 5 structures are omitted so each point is a meaningful average. A dashed trend line is drawn only if the change over time is statistically significant.

Read moreShow less — how each metric is calculated

Mean TM-score: the month's average shape-match score. TM̄ = (1/M) Σ TM over the M structures deposited that month.

Trend line: a monotonic-trend test over the monthly means — Mann-Kendall (Kendall's τ) for significance, with a robust Theil-Sen slope for the line. Rank-based, so it tolerates the skewed TM distribution and noisy low-count months. Shown only when p < 0.05; otherwise a note reports that no significant trend was found.

Confidently wrong: the count that were both confident and wrong. count( mean pLDDT > 70 AND TM < 0.5 ).

Matched structures

PDB	UniProt	Protein	Method	Å	Deposited	Novelty %	pLDDT	TM	lDDT	GDT_TS	RMSD	FRAUD	Flag
8XL2_A	Q13085	Acetyl-CoA carboxylase 1	EM	2.73	2023-12-25	55.20	87.25	0.50	0.87	1.31	33.45	0.81	ok
8XL1_A	Q13085	Acetyl-CoA carboxylase 1	EM	2.57	2023-12-25	55.20	87.25	0.50	0.87	1.31	33.46	0.81	ok
9DVG_A	P41212	Transcription factor ETV6,DARPin	X-ray	3.54	2024-10-07	1.30	59.38	0.37	0.42	0.38	39.31	0.57	ok
9G8M_E	Q9Y450	Isoform 2 of HBS1-like protein	EM	3.30	2024-07-23	100.00 novel	45.68	0.29	0.55	3.45	15.38	0.39	ok
9G8M_Sf	P62979	Ubiquitin	EM	3.30	2024-07-23	0.00	90.40	0.42	0.54	24.30	6.79	0.38	wrong
9G8M_LW	P83731	60S ribosomal protein L24	EM	3.30	2024-07-23	0.00	87.40	0.60	0.81	38.51	5.08	0.25	ok
9G8M_M	Q8TF46	DIS3-like exonuclease 1	EM	3.30	2024-07-23	—	84.06	0.71	—	—	—	0.25	ok
9G8M_SR	P08708	40S ribosomal protein S17	EM	3.30	2024-07-23	—	86.25	0.72	—	—	—	0.24	ok
8YHZ_P	Q15858	Sodium channel protein type 9 subunit alph	X-ray	1.62	2024-02-28	—	91.04	0.61	0.63	40.00	3.93	0.23	ok
9G8M_Se	P62861	40S ribosomal protein S30	EM	3.30	2024-07-23	—	91.00	0.75	—	—	—	0.23	ok
9EPQ_A	P63096	Guanine nucleotide-binding protein G(i) su	EM	4.15	2024-03-19	—	93.75	0.76	—	—	—	0.23	ok
9G8M_Sd	P62273	40S ribosomal protein S29	EM	3.30	2024-07-23	—	93.69	0.76	—	—	—	0.23	ok
9G8M_SP	P62841	40S ribosomal protein S15	EM	3.30	2024-07-23	—	86.44	0.74	—	—	—	0.22	ok
9G8M_J	Q9Y3B2	Exosome complex component CSL4	EM	3.30	2024-07-23	0.60	80.36	0.66	0.83	41.17	4.64	0.22	ok
8WU0_B	P01308	Insulin	X-ray	1.95	2023-10-19	0.00	48.25	0.49	0.42	26.67	8.25	0.21	ok
9G8M_SM	P25398	40S ribosomal protein S12	EM	3.30	2024-07-23	0.00	84.27	0.60	0.54	43.44	4.02	0.20	ok
9EPP_A	P63096	Guanine nucleotide-binding protein G(i) su	EM	4.06	2024-03-19	—	93.75	0.79	—	—	—	0.20	ok
8TM6_e	Q9Y244	Proteasome maturation protein	EM	2.80	2023-07-28	100.00 novel	89.85	0.65	0.85	51.70	4.04	0.20	ok
9G8M_Sc	P62857	40S ribosomal protein S28	EM	3.30	2024-07-23	—	91.00	0.79	—	—	—	0.19	ok
8TM5_e	Q9Y244	Proteasome maturation protein	EM	3.00	2023-07-28	100.00 novel	90.46	0.67	0.87	54.55	3.58	0.18	ok
8TM4_e	Q9Y244	Proteasome maturation protein	EM	3.00	2023-07-28	100.00 novel	90.71	0.68	0.87	56.96	3.44	0.18	ok
9G8M_SS	P62269	40S ribosomal protein S18	EM	3.30	2024-07-23	—	88.69	0.81	—	—	—	0.17	ok
9G8M_SZ	P62851	40S ribosomal protein S25	EM	3.30	2024-07-23	—	73.25	0.78	—	—	—	0.16	ok
8R5L_A	P16581	E-selectin	X-ray	2.20	2023-11-17	—	83.00	0.81	—	—	—	0.16	ok
8TM5_H	Q99436	Proteasome subunit beta type-7	EM	3.00	2023-07-28	—	90.38	0.83	—	—	—	0.15	ok
9G8M_La	P46776	60S ribosomal protein L27a	EM	3.30	2024-07-23	—	93.75	0.84	—	—	—	0.15	ok
8R5M_A	P16581	E-selectin	X-ray	2.49	2023-11-17	—	83.00	0.83	—	—	—	0.14	ok
9G8M_Lj	P61927	60S ribosomal protein L37	EM	3.30	2024-07-23	—	89.50	0.84	—	—	—	0.14	ok
9G8M_LR	P84098	60S ribosomal protein L19	EM	3.30	2024-07-23	—	94.75	0.85	—	—	—	0.14	ok
8QZM_K	Q9Y6K1	DNA (cytosine-5)-methyltransferase 3A	EM	3.10	2023-10-27	0.50	36.40	0.26	0.59	30.21	7.81	0.14	ok
9G8M_SU	P60866	40S ribosomal protein S20	EM	3.30	2024-07-23	—	85.25	0.83	—	—	—	0.14	ok
8WU0_A	P01308	Insulin	X-ray	1.95	2023-10-19	0.00	51.25	0.27	0.53	45.24	4.83	0.14	ok
9G8M_Ll	P62891	60S ribosomal protein L39	EM	3.30	2024-07-23	—	94.00	0.86	—	—	—	0.13	ok
9G8M_SK	P46783	40S ribosomal protein S10	EM	3.30	2024-07-23	—	73.81	0.83	—	—	—	0.12	ok
9G8M_Sb	P42677	40S ribosomal protein S27	EM	3.30	2024-07-23	—	92.44	0.87	—	—	—	0.12	ok
9EPQ_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	4.15	2024-03-19	—	89.56	0.87	—	—	—	0.12	ok
8TM4_H	Q99436	Proteasome subunit beta type-7	EM	3.00	2023-07-28	—	90.38	0.88	—	—	—	0.11	ok
8TM4_c	O95456	Proteasome assembly chaperone 1	EM	3.00	2023-07-28	—	81.75	0.86	—	—	—	0.11	ok
9G8M_Lg	P49207	60S ribosomal protein L34	EM	3.30	2024-07-23	—	90.38	0.88	—	—	—	0.11	ok
9G8M_SQ	P62249	40S ribosomal protein S16	EM	3.30	2024-07-23	—	93.88	0.88	—	—	—	0.11	ok
9EPP_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	4.06	2024-03-19	—	89.56	0.88	—	—	—	0.11	ok
8TM6_c	O95456	Proteasome assembly chaperone 1	EM	2.80	2023-07-28	—	81.75	0.87	—	—	—	0.11	ok
9G8M_SF	P46782	40S ribosomal protein S5	EM	3.30	2024-07-23	—	90.44	0.88	—	—	—	0.11	ok
9G8M_Lh	P42766	60S ribosomal protein L35	EM	3.30	2024-07-23	—	94.56	0.89	—	—	—	0.11	ok
8TM5_c	O95456	Proteasome assembly chaperone 1	EM	3.00	2023-07-28	—	81.75	0.87	—	—	—	0.10	ok
9G8M_Lb	P47914	60S ribosomal protein L29	EM	3.30	2024-07-23	—	81.44	0.87	—	—	—	0.10	ok
9G8M_Lc	P62888	60S ribosomal protein L30	EM	3.30	2024-07-23	—	88.00	0.88	—	—	—	0.10	ok
8QZM_D	P62807	Histone H2B type 1-C/E/F/G/I	EM	3.10	2023-10-27	—	88.12	0.88	—	—	—	0.10	ok
9G8M_K	Q06265	Exosome complex component RRP45	EM	3.30	2024-07-23	—	77.00	0.87	—	—	—	0.10	ok
9G8M_Lk	P63173	60S ribosomal protein L38	EM	3.30	2024-07-23	—	95.38	0.90	—	—	—	0.10	ok
9G8M_SY	P62847	40S ribosomal protein S24	EM	3.30	2024-07-23	—	88.69	0.89	—	—	—	0.10	ok
9G8M_A	Q15477	Helicase SKI2W	EM	3.30	2024-07-23	—	80.69	0.88	—	—	—	0.10	ok
9G8M_ST	P39019	40S ribosomal protein S19	EM	3.30	2024-07-23	—	92.00	0.90	—	—	—	0.09	ok
9JKB_R	P62877	E3 ubiquitin-protein ligase RBX1, N-termin	EM	3.93	2024-09-15	3.20	85.29	0.27	0.91	73.44	1.82	0.09	wrong
9G8M_Sa	P62854	40S ribosomal protein S26	EM	3.30	2024-07-23	—	85.81	0.89	—	—	—	0.09	ok
9G8M_Lm	P62987	Ubiquitin-60S ribosomal protein L40	EM	3.30	2024-07-23	—	93.50	0.90	—	—	—	0.09	ok
9G8M_SL	P62280	40S ribosomal protein S11	EM	3.30	2024-07-23	—	88.06	0.90	—	—	—	0.09	ok
9G8M_I	Q13868	Exosome complex component RRP4	EM	3.30	2024-07-23	—	81.25	0.89	—	—	—	0.09	ok
9G8M_Lp	P61513	60S ribosomal protein L37a	EM	3.30	2024-07-23	—	96.31	0.91	—	—	—	0.09	ok
8TM6_H	Q99436	Proteasome subunit beta type-7	EM	2.80	2023-07-28	—	90.38	0.90	—	—	—	0.09	ok
9G8M_SG	P62753	40S ribosomal protein S6	EM	3.30	2024-07-23	—	94.19	0.91	—	—	—	0.09	ok
9G8M_LU	P35268	60S ribosomal protein L22	EM	3.30	2024-07-23	—	83.94	0.90	—	—	—	0.08	ok
9G8M_SD	P23396	40S ribosomal protein S3	EM	3.30	2024-07-23	—	91.06	0.91	—	—	—	0.08	ok
9G8M_LL	P26373	60S ribosomal protein L13	EM	3.30	2024-07-23	—	95.38	0.92	—	—	—	0.08	ok
9G8M_G	Q5RKV6	Exosome complex component MTR3	EM	3.30	2024-07-23	—	80.44	0.90	—	—	—	0.08	ok
9G8M_Li	Q9Y3U8	60S ribosomal protein L36	EM	3.30	2024-07-23	—	93.12	0.92	—	—	—	0.08	ok
9G8M_LE	Q02878	Large ribosomal subunit protein eL6	EM	3.30	2024-07-23	—	82.81	0.91	—	—	—	0.08	ok
9G8M_Sg	P63244	Receptor of activated protein C kinase 1	EM	3.30	2024-07-23	—	92.44	0.92	—	—	—	0.07	ok
8WTA_A	O00206	Toll-like receptor 4	EM	2.90	2023-10-18	—	89.19	0.92	—	—	—	0.07	ok
9GWT_P	Q8TD46	Isoform 1 of Cell surface glycoprotein CD2	X-ray	2.89	2024-09-27	—	74.56	0.91	—	—	—	0.07	ok
9JKB_C	Q9UKT5	F-box only protein 4	EM	3.93	2024-09-15	—	78.38	0.91	—	—	—	0.07	ok
8UOH_A	P27448	MAP/microtubule affinity-regulating kinase	X-ray	2.15	2023-10-19	—	68.25	0.90	—	—	—	0.07	ok
9JKB_B	P63208	S-phase kinase-associated protein 1	EM	3.93	2024-09-15	—	90.12	0.92	—	—	—	0.07	ok
9G8M_LX	P62750	60S ribosomal protein L23a	EM	3.30	2024-07-23	—	89.31	0.92	—	—	—	0.07	ok
9G8M_LJ	P62913	60S ribosomal protein L11	EM	3.30	2024-07-23	—	91.56	0.93	—	—	—	0.07	ok
9G8M_SH	P62081	40S ribosomal protein S7	EM	3.30	2024-07-23	—	86.88	0.92	—	—	—	0.07	ok
9G8M_SI	P62241	40S ribosomal protein S8	EM	3.30	2024-07-23	—	93.00	0.93	—	—	—	0.07	ok
9G8M_LT	P46778	60S ribosomal protein L21	EM	3.30	2024-07-23	—	94.06	0.93	—	—	—	0.07	ok
8QZM_C	P0C0S8	Histone H2A type 1	EM	3.10	2023-10-27	—	91.12	0.93	—	—	—	0.06	ok
8WUB_A	Q9NPG2	Neuroglobin	X-ray	1.50	2023-10-20	—	95.19	0.94	—	—	—	0.06	ok
9G8M_SO	P62263	40S ribosomal protein S14	EM	3.30	2024-07-23	—	90.12	0.93	—	—	—	0.06	ok
9G8M_SV	P63220	40S ribosomal protein S21	EM	3.30	2024-07-23	—	95.50	0.94	—	—	—	0.06	ok
8TM3_D	P28066	Proteasome subunit alpha type-5	EM	3.00	2023-07-28	—	94.12	0.94	—	—	—	0.06	ok
8TM4_J	P49721	Proteasome subunit beta type-2	EM	3.00	2023-07-28	—	96.69	0.94	—	—	—	0.06	ok
9G8M_LM	P50914	60S ribosomal protein L14	EM	3.30	2024-07-23	—	76.56	0.93	—	—	—	0.06	ok
9G8M_LC	P36578	60S ribosomal protein L4	EM	3.30	2024-07-23	—	87.12	0.94	—	—	—	0.05	ok
9G8M_Lo	P83881	60S ribosomal protein L36a	EM	3.30	2024-07-23	—	94.31	0.94	—	—	—	0.05	ok
8UOL_A	P27448	MAP/microtubule affinity-regulating kinase	X-ray	1.90	2023-10-19	—	68.25	0.92	—	—	—	0.05	ok
8TM3_j	Q5JS54	Proteasome assembly chaperone 4	EM	3.00	2023-07-28	—	87.00	0.94	—	—	—	0.05	ok
8TM3_c	O95456	Proteasome assembly chaperone 1	EM	3.00	2023-07-28	—	81.75	0.94	—	—	—	0.05	ok
9G8M_SX	P62266	40S ribosomal protein S23	EM	3.30	2024-07-23	—	94.88	0.95	—	—	—	0.05	ok
8QT2_A	Q8IXJ6	NAD-dependent protein deacetylase sirtuin-	X-ray	1.65	2023-10-12	—	81.69	0.94	—	—	—	0.05	ok
9G8M_LF	P18124	Large ribosomal subunit protein uL30	EM	3.30	2024-07-23	—	93.94	0.95	—	—	—	0.05	ok
8QT1_A	Q8IXJ6	NAD-dependent protein deacetylase sirtuin-	X-ray	1.55	2023-10-12	—	81.69	0.94	—	—	—	0.05	ok
8TM4_D	P28066	Proteasome subunit alpha type-5	EM	3.00	2023-07-28	—	94.12	0.95	—	—	—	0.05	ok
9G8M_Le	P62910	60S ribosomal protein L32	EM	3.30	2024-07-23	—	92.38	0.95	—	—	—	0.05	ok
9G8M_LD	P46777	60S ribosomal protein L5	EM	3.30	2024-07-23	—	94.50	0.95	—	—	—	0.05	ok
8WSR_A	Q9BYF1	Angiotensin-converting enzyme 2	EM	2.99	2023-10-17	—	90.69	0.95	—	—	—	0.05	ok
9G8M_LG	P62424	60S ribosomal protein L7a	EM	3.30	2024-07-23	—	90.62	0.95	—	—	—	0.05	ok
8TM3_B	P25789	Proteasome subunit alpha type-4	EM	3.00	2023-07-28	—	93.50	0.95	—	—	—	0.05	ok
8UMG_A	O14646	Chromodomain-helicase-DNA-binding protein	X-ray	3.10	2023-10-17	—	62.09	0.93	—	—	—	0.05	ok
8TM3_i	Q9BT73	Proteasome assembly chaperone 3	EM	3.00	2023-07-28	—	92.94	0.95	—	—	—	0.05	ok
9G8M_Ld	P62899	60S ribosomal protein L31	EM	3.30	2024-07-23	—	87.94	0.95	—	—	—	0.04	ok
8WTA_C	Q9Y6Y9	Lymphocyte antigen 96	EM	2.90	2023-10-18	—	87.69	0.95	—	—	—	0.04	ok
8QT8_A	Q8IXJ6	NAD-dependent protein deacetylase sirtuin-	X-ray	1.65	2023-10-12	—	81.69	0.95	—	—	—	0.04	ok
8TM3_A	P25787	Proteasome subunit alpha type-2	EM	3.00	2023-07-28	—	94.75	0.95	—	—	—	0.04	ok
9G8M_F	Q15024	Exosome complex component RRP42	EM	3.30	2024-07-23	—	84.25	0.95	—	—	—	0.04	ok
8TM4_G	P60900	Proteasome subunit alpha type-6	EM	3.00	2023-07-28	—	96.06	0.95	—	—	—	0.04	ok
9G8M_SJ	P46781	40S ribosomal protein S9	EM	3.30	2024-07-23	—	88.12	0.95	—	—	—	0.04	ok
8TM5_D	P28066	Proteasome subunit alpha type-5	EM	3.00	2023-07-28	—	94.12	0.95	—	—	—	0.04	ok
9G8M_LI	Q96L21	Ribosomal protein uL16-like	EM	3.30	2024-07-23	—	94.75	0.95	—	—	—	0.04	ok
8TM5_G	P60900	Proteasome subunit alpha type-6	EM	3.00	2023-07-28	—	96.06	0.96	—	—	—	0.04	ok
8TM5_J	P49721	Proteasome subunit beta type-2	EM	3.00	2023-07-28	—	96.69	0.96	—	—	—	0.04	ok
9G8M_LS	Q02543	60S ribosomal protein L18a	EM	3.30	2024-07-23	—	96.31	0.96	—	—	—	0.04	ok
9G8M_LZ	P61353	60S ribosomal protein L27	EM	3.30	2024-07-23	—	94.31	0.96	—	—	—	0.04	ok
8TM6_D	P28066	Proteasome subunit alpha type-5	EM	2.80	2023-07-28	—	94.12	0.96	—	—	—	0.04	ok
8TM3_d	Q969U7	Proteasome assembly chaperone 2	EM	3.00	2023-07-28	—	92.50	0.96	—	—	—	0.04	ok
9G8M_LQ	Q07020	60S ribosomal protein L18	EM	3.30	2024-07-23	—	95.50	0.96	—	—	—	0.04	ok
9G8M_L	Q9NPD3	Exosome complex component RRP41	EM	3.30	2024-07-23	—	90.19	0.96	—	—	—	0.04	ok
9DUV_A	P68133	Actin, alpha skeletal muscle	EM	3.30	2024-10-04	—	95.12	0.96	—	—	—	0.04	ok
9G8M_LO	P40429	60S ribosomal protein L13a	EM	3.30	2024-07-23	—	95.75	0.96	—	—	—	0.04	ok
9G8M_SB	P61247	40S ribosomal protein S3a	EM	3.30	2024-07-23	—	82.94	0.95	—	—	—	0.04	ok
9DUU_A	P68133	Actin, alpha skeletal muscle	EM	3.40	2024-10-04	—	95.12	0.96	—	—	—	0.04	ok
9G8M_LH	P32969	60S ribosomal protein L9	EM	3.30	2024-07-23	—	94.12	0.96	—	—	—	0.04	ok
8TM6_G	P60900	Proteasome subunit alpha type-6	EM	2.80	2023-07-28	—	96.06	0.96	—	—	—	0.04	ok
9G8M_SN	P62277	40S ribosomal protein S13	EM	3.30	2024-07-23	—	94.06	0.96	—	—	—	0.04	ok
8TM4_I	P49720	Proteasome subunit beta type-3	EM	3.00	2023-07-28	—	97.31	0.96	—	—	—	0.04	ok
9G8M_SA	P08865	40S ribosomal protein SA	EM	3.30	2024-07-23	—	79.25	0.95	—	—	—	0.04	ok
8QT0_A	Q8IXJ6	NAD-dependent protein deacetylase sirtuin-	X-ray	1.85	2023-10-12	—	81.69	0.95	—	—	—	0.04	ok
9G8M_LV	P62829	60S ribosomal protein L23	EM	3.30	2024-07-23	—	92.62	0.96	—	—	—	0.04	ok
8XL0_A	Q13085	Acetyl-CoA carboxylase 1	EM	4.14	2023-12-25	—	82.81	0.96	—	—	—	0.04	ok
8XKZ_C	Q13085	Acetyl-CoA carboxylase 1	EM	2.55	2023-12-25	—	82.81	0.96	—	—	—	0.04	ok
8TM4_d	Q969U7	Proteasome assembly chaperone 2	EM	3.00	2023-07-28	—	92.50	0.96	—	—	—	0.04	ok
9G8M_Ln	P62945	60S ribosomal protein L41	EM	3.30	2024-07-23	4.00	94.64	0.69	0.93	97.92	0.63	0.04	ok
9DU7_A	Q14145	Kelch-like ECH-associated protein 1	X-ray	1.87	2024-10-02	—	90.06	0.96	—	—	—	0.04	ok
8TM6_d	Q969U7	Proteasome assembly chaperone 2	EM	2.80	2023-07-28	—	92.50	0.96	—	—	—	0.04	ok
9G8M_SC	P15880	40S ribosomal protein S2	EM	3.30	2024-07-23	—	80.94	0.96	—	—	—	0.03	ok
9G8M_LY	P61254	60S ribosomal protein L26	EM	3.30	2024-07-23	—	92.88	0.96	—	—	—	0.03	ok
8TM5_d	Q969U7	Proteasome assembly chaperone 2	EM	3.00	2023-07-28	—	92.50	0.97	—	—	—	0.03	ok
9G8M_SW	P62244	40S ribosomal protein S15a	EM	3.30	2024-07-23	—	93.06	0.97	—	—	—	0.03	ok
9G8M_SE	P62701	40S ribosomal protein S4, X isoform	EM	3.30	2024-07-23	—	95.56	0.97	—	—	—	0.03	ok
8TM3_C	O14818	Proteasome subunit alpha type-7	EM	3.00	2023-07-28	—	94.38	0.97	—	—	—	0.03	ok
8TM4_A	P25787	Proteasome subunit alpha type-2	EM	3.00	2023-07-28	—	94.75	0.97	—	—	—	0.03	ok
9G8M_Lr	P46779	60S ribosomal protein L28	EM	3.30	2024-07-23	—	92.69	0.97	—	—	—	0.03	ok
9G8M_N	Q96B26	Exosome complex component RRP43	EM	3.30	2024-07-23	—	85.88	0.96	—	—	—	0.03	ok
9G8M_LA	P62917	60S ribosomal protein L8	EM	3.30	2024-07-23	—	95.31	0.97	—	—	—	0.03	ok
9IZN_B	O15393	Transmembrane protease serine 2	X-ray	2.40	2024-08-01	—	79.38	0.96	—	—	—	0.03	ok
9G8M_LB	P39023	60S ribosomal protein L3	EM	3.30	2024-07-23	—	96.38	0.97	—	—	—	0.03	ok
8TM5_C	O14818	Proteasome subunit alpha type-7	EM	3.00	2023-07-28	—	94.38	0.97	—	—	—	0.03	ok
8TM4_C	O14818	Proteasome subunit alpha type-7	EM	3.00	2023-07-28	—	94.38	0.97	—	—	—	0.03	ok
8GCG_A	Q00987	E3 ubiquitin-protein ligase Mdm2	X-ray	1.47	2023-03-01	—	62.59	0.95	—	—	—	0.03	ok
9G8M_Lf	P18077	60S ribosomal protein L35a	EM	3.30	2024-07-23	—	95.56	0.97	—	—	—	0.03	ok
9G8M_LN	P61313	60S ribosomal protein L15	EM	3.30	2024-07-23	—	96.19	0.97	—	—	—	0.03	ok
8TM3_G	P60900	Proteasome subunit alpha type-6	EM	3.00	2023-07-28	—	96.06	0.97	—	—	—	0.03	ok
9G8M_O	Q9NQT4	Exosome complex component RRP46	EM	3.30	2024-07-23	—	84.44	0.97	—	—	—	0.03	ok
8TM4_B	P25789	Proteasome subunit alpha type-4	EM	3.00	2023-07-28	—	93.50	0.97	—	—	—	0.03	ok
8TM6_N	P28072	Proteasome subunit beta type-6	EM	2.80	2023-07-28	—	88.69	0.97	—	—	—	0.03	ok
8TM5_I	P49720	Proteasome subunit beta type-3	EM	3.00	2023-07-28	—	97.31	0.97	—	—	—	0.03	ok
8TM5_A	P25787	Proteasome subunit alpha type-2	EM	3.00	2023-07-28	—	94.75	0.97	—	—	—	0.03	ok
8TM6_C	O14818	Proteasome subunit alpha type-7	EM	2.80	2023-07-28	—	94.38	0.97	—	—	—	0.03	ok
8XEE_B	Q9UJW3	DNA (cytosine-5)-methyltransferase 3-like	X-ray	3.03	2023-12-11	—	86.44	0.97	—	—	—	0.02	ok
9G8M_LP	P18621	60S ribosomal protein L17	EM	3.30	2024-07-23	—	91.88	0.97	—	—	—	0.02	ok
9JKB_A	Q13616	Cullin-1	EM	3.93	2024-09-15	—	88.75	0.97	—	—	—	0.02	ok
8TM4_E	P25786	Proteasome subunit alpha type-1	EM	3.00	2023-07-28	—	91.88	0.97	—	—	—	0.02	ok
8TM3_E	P25786	Proteasome subunit alpha type-1	EM	3.00	2023-07-28	—	91.88	0.97	—	—	—	0.02	ok
8TM4_F	P25788	Proteasome subunit alpha type-3	EM	3.00	2023-07-28	—	94.50	0.98	—	—	—	0.02	ok
8I7T_A	P00519	Tyrosine-protein kinase ABL1	X-ray	2.80	2023-02-02	—	63.38	0.96	—	—	—	0.02	ok
8TM6_A	P25787	Proteasome subunit alpha type-2	EM	2.80	2023-07-28	—	94.75	0.98	—	—	—	0.02	ok
8TM5_B	P25789	Proteasome subunit alpha type-4	EM	3.00	2023-07-28	—	93.50	0.98	—	—	—	0.02	ok
9AVR_A	P60842	Eukaryotic initiation factor 4A-I	X-ray	1.91	2024-03-04	—	87.06	0.98	—	—	—	0.02	ok
8QSW_A	Q5T280	Putative methyltransferase C9orf114	X-ray	2.50	2023-10-11	—	88.38	0.98	—	—	—	0.02	ok
8TM5_F	P25788	Proteasome subunit alpha type-3	EM	3.00	2023-07-28	—	94.50	0.98	—	—	—	0.02	ok
8I7Z_A	P00519	Tyrosine-protein kinase ABL1	X-ray	2.25	2023-02-02	—	63.38	0.97	—	—	—	0.02	ok
8TM6_B	P25789	Proteasome subunit alpha type-4	EM	2.80	2023-07-28	—	93.50	0.98	—	—	—	0.02	ok
8QSV_A	Q5T280	Putative methyltransferase C9orf114	X-ray	2.62	2023-10-11	—	88.38	0.98	—	—	—	0.02	ok
8TM3_F	P25788	Proteasome subunit alpha type-3	EM	3.00	2023-07-28	—	94.50	0.98	—	—	—	0.02	ok
8QT3_A	Q8IXJ6	NAD-dependent protein deacetylase sirtuin-	X-ray	1.55	2023-10-12	—	81.69	0.98	—	—	—	0.02	ok
8QT4_A	Q8IXJ6	NAD-dependent protein deacetylase sirtuin-	X-ray	1.55	2023-10-12	—	81.69	0.98	—	—	—	0.02	ok
8QTU_A	Q8IXJ6	NAD-dependent protein deacetylase sirtuin-	X-ray	1.80	2023-10-13	—	81.69	0.98	—	—	—	0.02	ok
9DZM_C	P09086	POU domain, class 2, transcription factor	X-ray	2.54	2024-10-16	—	58.84	0.97	—	—	—	0.02	ok
8TM6_F	P25788	Proteasome subunit alpha type-3	EM	2.80	2023-07-28	—	94.50	0.98	—	—	—	0.01	ok
8QZM_B	P62805	Histone H4	EM	3.10	2023-10-27	—	89.81	0.98	—	—	—	0.01	ok
8TM5_E	P25786	Proteasome subunit alpha type-1	EM	3.00	2023-07-28	—	91.88	0.98	—	—	—	0.01	ok
9EPQ_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	4.15	2024-03-19	—	97.06	0.99	—	—	—	0.01	ok
8W4A_A	Q68CP4	Heparan-alpha-glucosaminide N-acetyltransf	EM	2.69	2023-08-23	—	79.88	0.98	—	—	—	0.01	ok
8QZM_A	A0A7K7T3V7	Histone H3 (Fragment)	EM	3.10	2023-10-27	—	86.69	0.99	—	—	—	0.01	ok
8QSU_A	Q5T280	Putative methyltransferase C9orf114	X-ray	2.38	2023-10-11	—	88.38	0.99	—	—	—	0.01	ok
9EPP_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	4.06	2024-03-19	—	97.06	0.99	—	—	—	0.01	ok
8WUZ_A	Q16740	ATP-dependent Clp protease proteolytic sub	X-ray	2.90	2023-10-22	—	82.31	0.99	—	—	—	0.01	ok
8UOK_A	P27448	MAP/microtubule affinity-regulating kinase	X-ray	1.85	2023-10-19	—	68.25	0.99	—	—	—	0.01	ok
8TM6_K	P28074	Proteasome subunit beta type-5	EM	2.80	2023-07-28	—	82.38	0.99	—	—	—	0.01	ok
8UOI_A	P27448	MAP/microtubule affinity-regulating kinase	X-ray	1.80	2023-10-19	—	68.25	0.99	—	—	—	0.01	ok
8TM6_E	P25786	Proteasome subunit alpha type-1	EM	2.80	2023-07-28	—	91.88	0.99	—	—	—	0.01	ok
8TM6_I	P49720	Proteasome subunit beta type-3	EM	2.80	2023-07-28	—	97.31	0.99	—	—	—	0.01	ok
8QUN_AAA	P00915	Carbonic anhydrase 1	X-ray	1.61	2023-10-16	—	96.81	0.99	—	—	—	0.01	ok
8UM5_A	Q92835	Phosphatidylinositol 3,4,5-trisphosphate 5	X-ray	1.86	2023-10-17	—	71.25	0.99	—	—	—	0.01	ok
8QUF_AAA	P00918	Carbonic anhydrase 2	X-ray	1.14	2023-10-16	—	97.38	0.99	—	—	—	0.01	ok
8PHM_A	P00918	Carbonic anhydrase 2	X-ray	1.45	2023-06-20	—	97.38	0.99	—	—	—	0.01	ok
8XEE_A	Q9UBC3	DNA (cytosine-5)-methyltransferase 3B	X-ray	3.03	2023-12-11	—	72.56	0.99	—	—	—	0.01	ok
8TM6_M	P28070	Proteasome subunit beta type-4	EM	2.80	2023-07-28	—	87.44	0.99	—	—	—	0.00	ok
8TM6_J	P49721	Proteasome subunit beta type-2	EM	2.80	2023-07-28	—	96.69	1.00	—	—	—	0.00	ok
8TM6_L	P20618	Proteasome subunit beta type-1	EM	2.80	2023-07-28	—	91.38	1.00	—	—	—	0.00	ok
8QTW_A	P06276	Cholinesterase	X-ray	2.24	2023-10-13	—	93.38	1.00	—	—	—	0.00	ok
8QTX_A	P06276	Cholinesterase	X-ray	2.12	2023-10-13	—	93.38	1.00	—	—	—	0.00	ok

Click a column header to sort. FRAUD = confidence-weighted error; a structure is flagged confidently wrong when mean pLDDT > 70 yet TM-score < 0.5.