Release week 2024-09-18
⭐ This week's notable releases
14 novel sequences, 4 confidently wrong. Highlight: Coiled-coil domain-containing protein 12.
| PDB | Protein | Flags | Why it matters |
|---|---|---|---|
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Coiled-coil domain-containing protein 12 | novel · 100% confidently wrong | Genuinely unseen sequence (0% identity to anything AlphaFold trained on) — and AlphaFold got the fold wrong despite high confidence. |
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Tuftelin-interacting protein 11 | novel · 100% | Genuinely unseen sequence (0% identity to anything AlphaFold trained on). |
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Prolyl 3-hydroxylase 1 | novel · 100% | Genuinely unseen sequence (0% identity to anything AlphaFold trained on). |
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Prolyl 3-hydroxylase 1 | novel · 100% | Genuinely unseen sequence (0% identity to anything AlphaFold trained on). |
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Prolyl 3-hydroxylase 1 | novel · 100% | Genuinely unseen sequence (0% identity to anything AlphaFold trained on). |
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Prolyl 3-hydroxylase 1 | novel · 100% | Genuinely unseen sequence (0% identity to anything AlphaFold trained on). |
Zoomed into the red "confidently wrong" box above (pLDDT ≥ 70, TM < 0.5) — the structures AlphaFold got confidently wrong.
The worst offenders ranked, one row per protein (AlphaFold has one model per sequence, so repeat depositions are collapsed — “×N” marks how many structures of that protein exist; the worst is shown). Each row joins what AlphaFold claimed (blue, pLDDT/100) to what the experiment showed (red, TM-score) — the longer the bar, the bigger the miss. Hover a dot to preview its Cα-deviation ribbon; click to open the full entry.
How to read this
Every point is one experimental protein structure. The horizontal axis is AlphaFold's own confidence in its prediction (mean pLDDT, 0–100). The vertical axis is how well that blind prediction actually matches the experiment (TM-score, 0–1; above 0.5 means the same fold, above 0.9 near-identical). Marker size grows with the FRAUD score (confidence-weighted error).
Cutoff: the shaded red box is the "confidently wrong" zone — AlphaFold was confident (mean pLDDT above 70) yet the fold is wrong (TM-score below 0.5). A predictor that had truly solved folding would leave that box empty.
Take-home: 4 of 142 structures (2.8%) are confidently wrong; median TM-score is 0.94.
Read moreShow less — how each metric is calculated
TM-score: how similar the two 3D shapes are overall, 0–1 (a random pair scores ~0.17, an identical fold ~1). Length-normalised so large and small proteins compare fairly. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) — dᵢ is the gap between the i-th aligned Cα atoms after best-fit superposition, and d₀ = 1.24(L−15)^⅓ − 1.8 sets the distance scale for length L. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264; computed with TM-align, doi:10.1093/nar/gki524.
pLDDT: AlphaFold's own confidence in each residue, 0–100 (higher = surer). It is the model predicting its own accuracy before ever seeing the experiment. We plot the per-structure mean. pLDDT = (1/N) Σᵢ pLDDTᵢ, where pLDDTᵢ is the network's confidence output for residue i.
FRAUD score: the headline number — how wrong the prediction was, weighted by how confident AlphaFold was, so a big error it was sure about counts most. FRAUD = (1/N) Σᵢ (pLDDTᵢ/100) · min(Δᵢ,15)/15, where Δᵢ is residue i's Cα distance from the experiment (Å) after superposition, capped at 15 Å. Runs 0 (perfect) to 1.
Novelty: how little AlphaFold had to go on — 100 minus the highest sequence identity between this protein and any structure released before the 2018-04-30 training cutoff. High = genuinely unseen (100% = nothing similar was ever in the training set). novelty = 100 − maxₚ identity(s, p) over pre-cutoff PDB chains p, with identity = 100 × (matching aligned residues)/(alignment length), from an MMseqs2 search.
Homology: the point colour. High novelty (above 70%) flags the sequence as novel (amber) — AlphaFold had no close template; otherwise a pre-cutoff homolog existed (blue) it could have learned the fold from. novel ⇔ novelty > 70%.
What the metrics mean
TM-score (0–1): overall fold match — above 0.5 is the same fold, above 0.9 near-identical. Cα-RMSD (Å): average backbone distance after best-fit superposition — lower is better (under 2 Å is excellent). lDDT (0–1): local accuracy measured without superposition — above 0.8 is good. Each bar counts how many structures fall in that range.
Take-home: median TM-score 0.94 — most predictions match the experimental fold well, with a long tail that do not.
Read moreShow less — how each metric is calculated
TM-score: overall shape match, 0–1 (above 0.5 = same fold, above 0.9 near-identical), length-normalised. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) with dᵢ the aligned-Cα gap after superposition and d₀ = 1.24(L−15)^⅓ − 1.8. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264.
Cα-RMSD: the average straight-line distance between matching backbone Cα atoms once the two structures are best-fit superposed (Å; lower is better, under ~2 Å excellent). RMSD = √( (1/N) Σᵢ |Pᵢ − (R·Qᵢ + t)|² ), with Pᵢ/Qᵢ the experimental/model Cα coordinates and R,t the rotation and translation from Kabsch superposition.
lDDT: local accuracy with no superposition — the fraction of short-range inter-residue distances the model reproduces, so it is not fooled by a single wrongly-placed domain. lDDT = (1/N) Σᵢ ¼ Σ_t 1[ |d_exp − d_model| < t ] over thresholds t ∈ {0.5, 1, 2, 4} Å and all residue pairs within 15 Å.
Trend over time
The blue line is the mean TM-score of the structures by their deposit month; the red bars count how many were confidently wrong. Binning by deposit date (rather than by when we processed them) gives an even timeline, tracking whether AlphaFold's accuracy on newly-deposited structures is holding steady, improving, or slipping as the PDB keeps growing. Months with fewer than 5 structures are omitted so each point is a meaningful average. A dashed trend line is drawn only if the change over time is statistically significant.
Read moreShow less — how each metric is calculated
Mean TM-score: the month's average shape-match score. TM̄ = (1/M) Σ TM over the M structures deposited that month.
Trend line: a monotonic-trend test over the monthly means — Mann-Kendall (Kendall's τ) for significance, with a robust Theil-Sen slope for the line. Rank-based, so it tolerates the skewed TM distribution and noisy low-count months. Shown only when p < 0.05; otherwise a note reports that no significant trend was found.
Confidently wrong: the count that were both confident and wrong. count( mean pLDDT > 70 AND TM < 0.5 ).
Matched structures
| PDB | UniProt | Protein | Method | Å | Deposited | Novelty % | pLDDT | TM | lDDT | GDT_TS | RMSD | FRAUD | Flag |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 8QUT_A | P61626 | Lysozyme C | EM | 2.80 | 2023-10-17 | 0.00 | 98.46 | 0.28 | 0.35 | 2.99 | 26.82 | 0.91 | wrong |
| 8RO2_q | Q9UMS4 | Pre-mRNA-processing factor 19 | EM | 3.50 | 2024-01-11 | 0.00 | 91.36 | 0.52 | 0.96 | 0.00 | 19.20 | 0.86 | ok |
| 8RO2_L | Q99459 | Cell division cycle 5-like protein | EM | 3.50 | 2024-01-11 | 0.00 | 82.68 | 0.41 | 0.85 | 0.00 | 59.07 | 0.82 | wrong |
| 8RO2_Z | Q8WUD4 | Coiled-coil domain-containing protein 12 | EM | 3.50 | 2024-01-11 | 100.00 novel | 82.92 | 0.41 | 0.86 | 0.00 | 22.55 | 0.81 | wrong |
| 8RO2_TF | Q9UBB9 | Tuftelin-interacting protein 11 | EM | 3.50 | 2024-01-11 | 100.00 novel | 85.89 | 0.55 | 0.89 | 2.01 | 42.03 | 0.80 | ok |
| 9DE2_A | O75081 | GATAD2A-MPPL motif and ETO2 NHR4 domain fu | NMR | — | 2024-08-28 | 21.10 | 84.98 | 0.56 | 0.56 | 3.41 | 16.60 | 0.72 | ok |
| 8K0M_A | Q32P28 | Prolyl 3-hydroxylase 1 | EM | 3.17 | 2023-07-09 | 100.00 novel | 90.79 | 0.62 | 0.85 | 5.21 | 14.38 | 0.72 | ok |
| 8K0F_A | Q32P28 | Prolyl 3-hydroxylase 1 | EM | 3.37 | 2023-07-08 | 100.00 novel | 90.80 | 0.63 | 0.85 | 5.20 | 14.33 | 0.72 | ok |
| 8KC9_A | Q32P28 | Prolyl 3-hydroxylase 1 | EM | 3.75 | 2023-08-06 | 100.00 novel | 90.49 | 0.62 | 0.82 | 5.14 | 14.86 | 0.72 | ok |
| 8K0E_A | Q32P28 | Prolyl 3-hydroxylase 1 | EM | 3.65 | 2023-07-08 | 100.00 novel | 90.33 | 0.62 | 0.81 | 5.07 | 15.03 | 0.72 | ok |
| 8K17_A | Q32P28 | Prolyl 3-hydroxylase 1 | EM | 3.18 | 2023-07-10 | 100.00 novel | 90.33 | 0.62 | 0.84 | 5.11 | 15.00 | 0.72 | ok |
| 8RO2_P | Q9P013 | Spliceosome-associated protein CWC15 homol | EM | 3.50 | 2024-01-11 | 0.00 | 78.82 | 0.61 | 0.73 | 2.90 | 19.44 | 0.67 | ok |
| 8IRJ_A | Q6PRD1 | Probable G-protein coupled receptor 179 | EM | 3.49 | 2023-03-17 | 100.00 novel | 79.74 | 0.55 | 0.80 | 4.19 | 16.74 | 0.63 | ok |
| 8RO2_I | Q9HCS7 | Pre-mRNA-splicing factor SYF1 | EM | 3.50 | 2024-01-11 | 0.00 | 77.39 | 0.61 | 0.88 | 16.67 | 18.93 | 0.47 | ok |
| 8U5X_A | Q7Z3F1 | Integral membrane protein GPR155 | EM | 2.79 | 2023-09-13 | 71.70 novel | 85.20 | 0.67 | 0.90 | 15.33 | 8.68 | 0.45 | ok |
| 8U5N_A | Q7Z3F1 | Integral membrane protein GPR155 | EM | 3.00 | 2023-09-12 | 71.70 novel | 84.81 | 0.67 | 0.90 | 16.25 | 8.68 | 0.45 | ok |
| 8RO2_M | O95926 | Pre-mRNA-splicing factor SYF2 | EM | 3.50 | 2024-01-11 | 0.00 | 89.05 | 0.49 | 0.90 | 20.48 | 7.38 | 0.41 | wrong |
| 8U5C_E | Q7Z3F1 | Integral membrane protein GPR155 | EM | 2.68 | 2023-09-12 | 71.70 novel | 84.91 | 0.67 | 0.88 | 21.00 | 7.42 | 0.39 | ok |
| 8U58_A | Q7Z3F1 | Integral membrane protein GPR155 | EM | 2.45 | 2023-09-12 | 71.70 novel | 85.37 | 0.69 | 0.88 | 21.19 | 7.26 | 0.39 | ok |
| 8U54_A | Q7Z3F1 | Integral membrane protein GPR155 | EM | 2.65 | 2023-09-12 | 71.70 novel | 83.72 | 0.67 | 0.87 | 21.35 | 7.46 | 0.38 | ok |
| 8XOR_A | P63096 | G subunit q (Gi1-Gq chimeric) | EM | 3.00 | 2024-01-02 | — | 93.75 | 0.75 | — | — | — | 0.23 | ok |
| 9A40_D | P62877 | RBX1_HUMAN | Integrative | — | 2023-12-18 | — | 79.25 | 0.72 | — | — | — | 0.22 | ok |
| 8WDK_R | P62877 | E3 ubiquitin-protein ligase RBX1, N-termin | EM | 3.64 | 2023-09-15 | — | 79.25 | 0.72 | — | — | — | 0.22 | ok |
| 8U5V_A | Q7Z3F1 | Integral membrane protein GPR155 | EM | 2.77 | 2023-09-13 | — | 73.25 | 0.70 | — | — | — | 0.22 | ok |
| 8U56_A | Q7Z3F1 | Integral membrane protein GPR155 | EM | 2.75 | 2023-09-12 | — | 73.25 | 0.71 | — | — | — | 0.21 | ok |
| 8RO2_PX | Q9Y5B6 | PAX3- and PAX7-binding protein 1 | EM | 3.50 | 2024-01-11 | — | 71.75 | 0.70 | — | — | — | 0.21 | ok |
| 9F33_A | P09471 | Guanine nucleotide-binding protein G(o) su | EM | 3.05 | 2024-04-24 | — | 94.50 | 0.78 | — | — | — | 0.21 | ok |
| 9F34_A | P09471 | Guanine nucleotide-binding protein G(o) su | EM | 3.09 | 2024-04-24 | — | 94.50 | 0.78 | — | — | — | 0.21 | ok |
| 9A40_A | Q13619 | CUL4A_HUMAN | Integrative | — | 2023-12-18 | — | 88.56 | 0.78 | — | — | — | 0.19 | ok |
| 8U5Q_A | Q7Z3F1 | Integral membrane protein GPR155 | EM | 2.40 | 2023-09-12 | — | 73.25 | 0.74 | — | — | — | 0.19 | ok |
| 8RO2_J | Q9BZJ0 | Crooked neck-like protein 1 | EM | 3.50 | 2024-01-11 | — | 74.44 | 0.76 | — | — | — | 0.18 | ok |
| 9A40_C | Q16531 | DDB1_HUMAN | Integrative | — | 2023-12-18 | — | 92.00 | 0.81 | — | — | — | 0.17 | ok |
| 8RO2_b | P14678 | Small nuclear ribonucleoprotein-associated | EM | 3.50 | 2024-01-11 | — | 69.50 | 0.76 | — | — | — | 0.17 | ok |
| 8YW3_R | P43220 | Glucagon-like peptide 1 receptor | EM | 2.68 | 2024-03-29 | — | 81.50 | 0.80 | — | — | — | 0.16 | ok |
| 8RO2_D | Q9ULR0 | Pre-mRNA-splicing factor ISY1 homolog | EM | 3.50 | 2024-01-11 | — | 80.19 | 0.80 | — | — | — | 0.16 | ok |
| 8XOS_A | P63096 | Guanine nucleotide-binding protein G(i) su | EM | 3.20 | 2024-01-02 | — | 93.75 | 0.83 | — | — | — | 0.16 | ok |
| 8Z9X_A | P28288 | ATP-binding cassette sub-family D member 3 | EM | 2.96 | 2024-04-23 | — | 82.88 | 0.81 | — | — | — | 0.16 | ok |
| 8WZO_A | O60260 | E3 ubiquitin-protein ligase parkin | X-ray | 2.25 | 2023-11-02 | — | 78.06 | 0.81 | — | — | — | 0.15 | ok |
| 8RO2_R | Q13573 | SNW domain-containing protein 1 | EM | 3.50 | 2024-01-11 | — | 78.50 | 0.82 | — | — | — | 0.14 | ok |
| 8WZN_A | O60260 | E3 ubiquitin-protein ligase parkin | X-ray | 1.80 | 2023-11-02 | — | 78.06 | 0.82 | — | — | — | 0.14 | ok |
| 8RO2_K | O75934 | Pre-mRNA-splicing factor SPF27 | EM | 3.50 | 2024-01-11 | — | 88.88 | 0.85 | — | — | — | 0.13 | ok |
| 9B1L_A | Q96S37 | Solute carrier family 22 member 12 | EM | 3.10 | 2024-03-13 | — | 86.56 | 0.86 | — | — | — | 0.12 | ok |
| 8YW4_A | P63092 | Mini-Gs | EM | 3.26 | 2024-03-29 | — | 91.31 | 0.87 | — | — | — | 0.11 | ok |
| 8YW3_A | P63092 | Guanine nucleotide-binding protein G(s) su | EM | 2.68 | 2024-03-29 | — | 91.31 | 0.88 | — | — | — | 0.11 | ok |
| 8RO2_d | P62316 | Small nuclear ribonucleoprotein Sm D2 | EM | 3.50 | 2024-01-11 | — | 90.62 | 0.88 | — | — | — | 0.11 | ok |
| 8RO2_T | O43660 | Pleiotropic regulator 1 | EM | 3.50 | 2024-01-11 | — | 77.38 | 0.87 | — | — | — | 0.10 | ok |
| 8RO2_A | Q6P2Q9 | Pre-mRNA-processing-splicing factor 8 | EM | 3.50 | 2024-01-11 | — | 84.94 | 0.89 | — | — | — | 0.10 | ok |
| 8YW4_R | P48546 | Gastric inhibitory polypeptide receptor | EM | 3.26 | 2024-03-29 | — | 78.50 | 0.88 | — | — | — | 0.09 | ok |
| 8RO2_W | O60508 | Pre-mRNA-processing factor 17 | EM | 3.50 | 2024-01-11 | — | 85.81 | 0.89 | — | — | — | 0.09 | ok |
| 8RO2_z | Q6IQ49 | Splicing regulator SDE2 | EM | 3.50 | 2024-01-11 | 100.00 novel | 90.90 | 0.59 | 0.95 | 78.00 | 1.55 | 0.08 | ok |
| 8RO2_N | P41223 | Protein BUD31 homolog | EM | 3.50 | 2024-01-11 | — | 90.75 | 0.91 | — | — | — | 0.08 | ok |
| 9A40_B | Q9Y4B6 | DCAF1_HUMAN | Integrative | — | 2023-12-18 | — | 74.94 | 0.90 | — | — | — | 0.08 | ok |
| 9F33_C | P59768 | Guanine nucleotide-binding protein G(I)/G( | EM | 3.05 | 2024-04-24 | — | 89.56 | 0.92 | — | — | — | 0.07 | ok |
| 8RO2_g | P62308 | Small nuclear ribonucleoprotein G | EM | 3.50 | 2024-01-11 | — | 93.25 | 0.93 | — | — | — | 0.07 | ok |
| 9BD2_A | P43357 | Melanoma-associated antigen 3 | X-ray | 2.24 | 2024-04-10 | — | 71.44 | 0.90 | — | — | — | 0.07 | ok |
| 8K0I_A | Q32P28 | Prolyl 3-hydroxylase 1 | EM | 3.62 | 2023-07-09 | — | 85.75 | 0.92 | — | — | — | 0.07 | ok |
| 9F34_C | P59768 | Guanine nucleotide-binding protein G(I)/G( | EM | 3.09 | 2024-04-24 | — | 89.56 | 0.93 | — | — | — | 0.07 | ok |
| 8K0E_B | O75718 | Cartilage-associated protein | EM | 3.65 | 2023-07-08 | — | 88.31 | 0.93 | — | — | — | 0.07 | ok |
| 8K0I_B | O75718 | Cartilage-associated protein | EM | 3.62 | 2023-07-09 | — | 88.31 | 0.93 | — | — | — | 0.06 | ok |
| 8X8A_B | O95210 | Starch-binding domain-containing protein 1 | X-ray | 1.53 | 2023-11-27 | — | 44.35 | 0.30 | 0.86 | 61.54 | 2.33 | 0.06 | ok |
| 8RO2_e | P62304 | Small nuclear ribonucleoprotein E | EM | 3.50 | 2024-01-11 | — | 90.75 | 0.93 | — | — | — | 0.06 | ok |
| 8YW4_G | P59768 | Guanine nucleotide-binding protein G(I)/G( | EM | 3.26 | 2024-03-29 | — | 89.56 | 0.93 | — | — | — | 0.06 | ok |
| 9B1K_A | Q96S37 | Solute carrier family 22 member 12 | EM | 3.30 | 2024-03-13 | — | 86.56 | 0.93 | — | — | — | 0.06 | ok |
| 8KC9_B | O75718 | Cartilage-associated protein | EM | 3.75 | 2023-08-06 | — | 88.31 | 0.93 | — | — | — | 0.06 | ok |
| 8WZN_B | Q15843 | NEDD8 | X-ray | 1.80 | 2023-11-02 | — | 89.94 | 0.94 | — | — | — | 0.06 | ok |
| 8RO2_L2 | Q2TBE0 | CWF19-like protein 2 | EM | 3.50 | 2024-01-11 | — | 66.31 | 0.91 | — | — | — | 0.06 | ok |
| 8RO2_3 | Q96DF8 | Splicing factor ESS-2 homolog | EM | 3.50 | 2024-01-11 | — | 67.25 | 0.92 | — | — | — | 0.06 | ok |
| 8WDK_C | Q15369 | Elongin-C | EM | 3.64 | 2023-09-15 | — | 89.81 | 0.94 | — | — | — | 0.05 | ok |
| 8K0F_B | O75718 | Cartilage-associated protein | EM | 3.37 | 2023-07-08 | — | 88.31 | 0.94 | — | — | — | 0.05 | ok |
| 8WZO_B | Q15843 | NEDD8 | X-ray | 2.25 | 2023-11-02 | — | 89.94 | 0.94 | — | — | — | 0.05 | ok |
| 8WDK_A | Q13617 | Cullin-2 | EM | 3.64 | 2023-09-15 | — | 85.75 | 0.94 | — | — | — | 0.05 | ok |
| 8K0M_B | O75718 | Cartilage-associated protein | EM | 3.17 | 2023-07-09 | — | 88.31 | 0.94 | — | — | — | 0.05 | ok |
| 8YW3_G | P59768 | Guanine nucleotide-binding protein G(I)/G( | EM | 2.68 | 2024-03-29 | — | 89.56 | 0.94 | — | — | — | 0.05 | ok |
| 8K17_B | O75718 | Cartilage-associated protein | EM | 3.18 | 2023-07-10 | — | 88.31 | 0.94 | — | — | — | 0.05 | ok |
| 8Z7N_C | P01730 | T-cell surface glycoprotein CD4 | EM | 3.58 | 2024-04-20 | — | 85.25 | 0.95 | — | — | — | 0.05 | ok |
| 8WDK_B | Q15370 | Elongin-B | EM | 3.64 | 2023-09-15 | — | 92.50 | 0.95 | — | — | — | 0.05 | ok |
| 8RO2_f | P62306 | Small nuclear ribonucleoprotein F | EM | 3.50 | 2024-01-11 | — | 90.50 | 0.95 | — | — | — | 0.04 | ok |
| 8KC9_C | P23284 | Peptidyl-prolyl cis-trans isomerase B | EM | 3.75 | 2023-08-06 | — | 91.81 | 0.95 | — | — | — | 0.04 | ok |
| 8XOR_R | P25116 | Proteinase-activated receptor 1 LgBiT | EM | 3.00 | 2024-01-02 | — | 74.56 | 0.94 | — | — | — | 0.04 | ok |
| 8RO2_c | P62314 | Small nuclear ribonucleoprotein Sm D1 | EM | 3.50 | 2024-01-11 | — | 82.81 | 0.95 | — | — | — | 0.04 | ok |
| 8K17_C | P23284 | Peptidyl-prolyl cis-trans isomerase B | EM | 3.18 | 2023-07-10 | — | 91.81 | 0.96 | — | — | — | 0.04 | ok |
| 8WDK_W | P30291 | Wee1-like protein kinase | EM | 3.64 | 2023-09-15 | — | 65.31 | 0.94 | — | — | — | 0.04 | ok |
| 8K0I_C | P23284 | Peptidyl-prolyl cis-trans isomerase B | EM | 3.62 | 2023-07-09 | — | 91.81 | 0.96 | — | — | — | 0.04 | ok |
| 8RO2_a | P62318 | Small nuclear ribonucleoprotein Sm D3 | EM | 3.50 | 2024-01-11 | — | 82.81 | 0.96 | — | — | — | 0.03 | ok |
| 8XOS_R | P25116 | Proteinase-activated receptor 1 LgBiT | EM | 3.20 | 2024-01-02 | — | 74.56 | 0.95 | — | — | — | 0.03 | ok |
| 8WDK_V | P40337 | von Hippel-Lindau disease tumor suppressor | EM | 3.64 | 2023-09-15 | — | 84.44 | 0.96 | — | — | — | 0.03 | ok |
| 8RO2_O | Q9NW64 | Pre-mRNA-splicing factor RBM22 | EM | 3.50 | 2024-01-11 | — | 76.12 | 0.96 | — | — | — | 0.03 | ok |
| 8K0F_C | P23284 | Peptidyl-prolyl cis-trans isomerase B | EM | 3.37 | 2023-07-08 | — | 91.81 | 0.97 | — | — | — | 0.03 | ok |
| 8ZBQ_D | Q9BYF1 | Angiotensin-converting enzyme 2 | EM | 3.03 | 2024-04-27 | — | 90.69 | 0.97 | — | — | — | 0.03 | ok |
| 8K0M_C | P23284 | Peptidyl-prolyl cis-trans isomerase B | EM | 3.17 | 2023-07-09 | — | 91.81 | 0.97 | — | — | — | 0.03 | ok |
| 9EQG_A | P14867 | Gamma-aminobutyric acid receptor subunit a | EM | 2.40 | 2024-03-21 | — | 81.69 | 0.97 | — | — | — | 0.02 | ok |
| 8RO2_S | Q9Y3C6 | Peptidyl-prolyl cis-trans isomerase-like 1 | EM | 3.50 | 2024-01-11 | — | 94.75 | 0.97 | — | — | — | 0.02 | ok |
| 8QHG_A | P00918 | Carbonic anhydrase 2 | X-ray | 1.91 | 2023-09-08 | — | 97.38 | 0.98 | — | — | — | 0.02 | ok |
| 8Z0F_A | P28288 | ATP-binding cassette sub-family D member 3 | EM | 3.27 | 2024-04-09 | — | 82.88 | 0.97 | — | — | — | 0.02 | ok |
| 9B1I_A | Q96S37 | Solute carrier family 22 member 12 | EM | 3.70 | 2024-03-13 | — | 86.56 | 0.97 | — | — | — | 0.02 | ok |
| 8ZYQ_A | Q12809 | Potassium voltage-gated channel subfamily | EM | 3.18 | 2024-06-18 | — | 62.75 | 0.96 | — | — | — | 0.02 | ok |
| 9FJ3_A | P0CG48 | Polyubiquitin-C | X-ray | 1.40 | 2024-05-30 | — | 88.62 | 0.97 | — | — | — | 0.02 | ok |
| 9B1G_A | Q96S37 | Solute carrier family 22 member 12 | EM | 2.70 | 2024-03-13 | — | 86.56 | 0.97 | — | — | — | 0.02 | ok |
| 8ZYO_A | Q12809 | Potassium voltage-gated channel subfamily | EM | 3.29 | 2024-06-18 | — | 62.75 | 0.96 | — | — | — | 0.02 | ok |
| 8X8A_A | Q9H0R8 | Gamma-aminobutyric acid receptor-associate | X-ray | 1.53 | 2023-11-27 | — | 95.00 | 0.98 | — | — | — | 0.02 | ok |
| 8X8K_A | O95210 | Starch-binding domain-containing protein 1 | X-ray | 2.10 | 2023-11-27 | — | 57.12 | 0.97 | — | — | — | 0.02 | ok |
| 9FJ4_A | P0CG48 | Polyubiquitin-C | X-ray | 1.54 | 2024-05-30 | — | 88.62 | 0.98 | — | — | — | 0.02 | ok |
| 8RO2_C | Q15029 | 116 kDa U5 small nuclear ribonucleoprotein | EM | 3.50 | 2024-01-11 | — | 89.94 | 0.98 | — | — | — | 0.02 | ok |
| 8ZYP_A | Q12809 | Potassium voltage-gated channel subfamily | EM | 3.19 | 2024-06-18 | — | 62.75 | 0.97 | — | — | — | 0.02 | ok |
| 8ZYN_A | Q12809 | Potassium voltage-gated channel subfamily | EM | 3.27 | 2024-06-18 | — | 62.75 | 0.97 | — | — | — | 0.02 | ok |
| 9B1J_A | Q96S37 | Solute carrier family 22 member 12 | EM | 3.00 | 2024-03-13 | — | 86.56 | 0.98 | — | — | — | 0.02 | ok |
| 8QW1_A | Q13232 | Nucleoside diphosphate kinase 3 | X-ray | 2.10 | 2023-10-18 | — | 92.31 | 0.98 | — | — | — | 0.02 | ok |
| 8QW2_A | Q13232 | Nucleoside diphosphate kinase 3 | X-ray | 1.87 | 2023-10-18 | — | 92.31 | 0.98 | — | — | — | 0.02 | ok |
| 8QVZ_A | Q13232 | Nucleoside diphosphate kinase 3 | X-ray | 1.77 | 2023-10-18 | — | 92.31 | 0.98 | — | — | — | 0.02 | ok |
| 8QVY_A | Q13232 | Nucleoside diphosphate kinase 3 | X-ray | 2.64 | 2023-10-18 | — | 92.31 | 0.98 | — | — | — | 0.01 | ok |
| 8QW3_A | Q13232 | Nucleoside diphosphate kinase 3 | X-ray | 1.25 | 2023-10-18 | — | 92.31 | 0.98 | — | — | — | 0.01 | ok |
| 8QW0_A | Q13232 | Nucleoside diphosphate kinase 3 | X-ray | 2.17 | 2023-10-18 | — | 92.31 | 0.98 | — | — | — | 0.01 | ok |
| 8YW4_B | P62873 | Guanine nucleotide-binding protein G(I)/G( | EM | 3.26 | 2024-03-29 | — | 97.06 | 0.99 | — | — | — | 0.01 | ok |
| 9CE4_A | O14757 | Serine/threonine-protein kinase Chk1 | X-ray | 1.31 | 2024-06-26 | — | 76.12 | 0.98 | — | — | — | 0.01 | ok |
| 8RO2_L1 | Q69YN2 | CWF19-like protein 1 | EM | 3.50 | 2024-01-11 | — | 83.38 | 0.98 | — | — | — | 0.01 | ok |
| 9B1M_A | Q96S37 | Solute carrier family 22 member 12 | EM | 3.00 | 2024-03-13 | — | 86.56 | 0.99 | — | — | — | 0.01 | ok |
| 9B1O_A | Q96S37 | Solute carrier family 22 member 12 | EM | 3.10 | 2024-03-13 | — | 86.56 | 0.99 | — | — | — | 0.01 | ok |
| 9B1N_A | Q96S37 | Solute carrier family 22 member 12 | EM | 3.10 | 2024-03-13 | — | 86.56 | 0.99 | — | — | — | 0.01 | ok |
| 9B1F_A | Q96S37 | Solute carrier family 22 member 12 | EM | 2.90 | 2024-03-13 | — | 86.56 | 0.99 | — | — | — | 0.01 | ok |
| 9B1H_A | Q96S37 | Solute carrier family 22 member 12 | EM | 2.90 | 2024-03-13 | — | 86.56 | 0.99 | — | — | — | 0.01 | ok |
| 8RO2_Q | O60306 | Intron-binding protein aquarius | EM | 3.50 | 2024-01-11 | — | 83.94 | 0.99 | — | — | — | 0.01 | ok |
| 9GBE_A | Q9UM73 | ALK tyrosine kinase receptor | X-ray | 1.58 | 2024-07-31 | — | 68.19 | 0.98 | — | — | — | 0.01 | ok |
| 9FB8_A | Q9H611 | ATP-dependent DNA helicase PIF1 | X-ray | 1.73 | 2024-05-12 | — | 78.00 | 0.99 | — | — | — | 0.01 | ok |
| 8VDH_F | P17947 | Transcription factor PU.1 | X-ray | 1.64 | 2023-12-15 | — | 65.50 | 0.98 | — | — | — | 0.01 | ok |
| 8VDI_F | P17947 | Transcription factor PU.1 | X-ray | 1.93 | 2023-12-15 | — | 65.50 | 0.98 | — | — | — | 0.01 | ok |
| 9EQG_B | P28472 | Gamma-aminobutyric acid receptor subunit b | EM | 2.40 | 2024-03-21 | — | 80.06 | 0.99 | — | — | — | 0.01 | ok |
| 8YW3_B | P62873 | Guanine nucleotide-binding protein G(I)/G( | EM | 2.68 | 2024-03-29 | — | 97.06 | 0.99 | — | — | — | 0.01 | ok |
| 8RO2_DX | O43143 | ATP-dependent RNA helicase DHX15 | EM | 3.50 | 2024-01-11 | — | 85.88 | 0.99 | — | — | — | 0.01 | ok |
| 9CHW_A | Q9Y253 | DNA polymerase eta | X-ray | 2.16 | 2024-07-02 | — | 76.88 | 0.99 | — | — | — | 0.01 | ok |
| 9EQG_C | P18507 | Gamma-aminobutyric acid receptor subunit g | EM | 2.40 | 2024-03-21 | — | 77.19 | 0.99 | — | — | — | 0.01 | ok |
| 9CJ9_A | Q9Y253 | DNA polymerase eta | X-ray | 2.98 | 2024-07-05 | — | 76.88 | 0.99 | — | — | — | 0.01 | ok |
| 8QHO_AAA | P00918 | Carbonic anhydrase 2 | X-ray | 1.43 | 2023-09-08 | — | 97.38 | 0.99 | — | — | — | 0.01 | ok |
| 8RO2_E | Q96DI7 | U5 small nuclear ribonucleoprotein 40 kDa | EM | 3.50 | 2024-01-11 | — | 85.25 | 0.99 | — | — | — | 0.01 | ok |
| 8QH8_A | P00918 | Carbonic anhydrase 2 | X-ray | 1.04 | 2023-09-06 | — | 97.38 | 0.99 | — | — | — | 0.01 | ok |
| 8WEP_A | P00918 | Carbonic anhydrase 2 | X-ray | 1.20 | 2023-09-18 | — | 97.38 | 1.00 | — | — | — | 0.00 | ok |
| 9GLE_A | O75164 | Lysine-specific demethylase 4A | X-ray | 1.88 | 2024-08-27 | — | 71.81 | 0.99 | — | — | — | 0.00 | ok |
| 8QHJ_A | P00918 | Carbonic anhydrase 2 | X-ray | 1.62 | 2023-09-08 | — | 97.38 | 1.00 | — | — | — | 0.00 | ok |
| 8WES_A | P00918 | Carbonic anhydrase 2 | X-ray | 1.45 | 2023-09-18 | — | 97.38 | 1.00 | — | — | — | 0.00 | ok |
| 8WER_A | P00918 | Carbonic anhydrase 2 | X-ray | 1.42 | 2023-09-18 | — | 97.38 | 1.00 | — | — | — | 0.00 | ok |
| 9CIQ_A | Q9Y253 | DNA polymerase eta | X-ray | 2.80 | 2024-07-04 | — | 76.88 | 1.00 | — | — | — | 0.00 | ok |
| 9CI9_A | Q9Y253 | DNA polymerase eta | X-ray | 2.09 | 2024-07-02 | — | 76.88 | 1.00 | — | — | — | 0.00 | ok |
| 9CIH_A | Q9Y253 | DNA polymerase eta | X-ray | 2.15 | 2024-07-03 | — | 76.88 | 1.00 | — | — | — | 0.00 | ok |
Click a column header to sort. FRAUD = confidence-weighted error; a structure is flagged confidently wrong when mean pLDDT > 70 yet TM-score < 0.5.