Release week 2023-10-18

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254

structures analysed (14 full · 5.5%)

00.0%

confidently wrong

00.0%

novel sequences

00.0%

novel & wrong

0.938

median TM-score

⭐ This week's notable releases

No novel or confidently-wrong structures this week — AlphaFold kept up.

Zoomed into the red "confidently wrong" box above (pLDDT ≥ 70, TM < 0.5) — the structures AlphaFold got confidently wrong.

How to read this

Every point is one experimental protein structure. The horizontal axis is AlphaFold's own confidence in its prediction (mean pLDDT, 0–100). The vertical axis is how well that blind prediction actually matches the experiment (TM-score, 0–1; above 0.5 means the same fold, above 0.9 near-identical). Marker size grows with the FRAUD score (confidence-weighted error).

Cutoff: the shaded red box is the "confidently wrong" zone — AlphaFold was confident (mean pLDDT above 70) yet the fold is wrong (TM-score below 0.5). A predictor that had truly solved folding would leave that box empty.

Take-home: 0 of 254 structures (0.0%) are confidently wrong; median TM-score is 0.938.

Read moreShow less — how each metric is calculated

TM-score: how similar the two 3D shapes are overall, 0–1 (a random pair scores ~0.17, an identical fold ~1). Length-normalised so large and small proteins compare fairly. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) — dᵢ is the gap between the i-th aligned Cα atoms after best-fit superposition, and d₀ = 1.24(L−15)^⅓ − 1.8 sets the distance scale for length L. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264; computed with TM-align, doi:10.1093/nar/gki524.

pLDDT: AlphaFold's own confidence in each residue, 0–100 (higher = surer). It is the model predicting its own accuracy before ever seeing the experiment. We plot the per-structure mean. pLDDT = (1/N) Σᵢ pLDDTᵢ, where pLDDTᵢ is the network's confidence output for residue i.

FRAUD score: the headline number — how wrong the prediction was, weighted by how confident AlphaFold was, so a big error it was sure about counts most. FRAUD = (1/N) Σᵢ (pLDDTᵢ/100) · min(Δᵢ,15)/15, where Δᵢ is residue i's Cα distance from the experiment (Å) after superposition, capped at 15 Å. Runs 0 (perfect) to 1.

Novelty: how little AlphaFold had to go on — 100 minus the highest sequence identity between this protein and any structure released before the 2018-04-30 training cutoff. High = genuinely unseen (100% = nothing similar was ever in the training set). novelty = 100 − maxₚ identity(s, p) over pre-cutoff PDB chains p, with identity = 100 × (matching aligned residues)/(alignment length), from an MMseqs2 search.

Homology: the point colour. High novelty (above 70%) flags the sequence as novel (amber) — AlphaFold had no close template; otherwise a pre-cutoff homolog existed (blue) it could have learned the fold from. novel ⇔ novelty > 70%.

What the metrics mean

TM-score (0–1): overall fold match — above 0.5 is the same fold, above 0.9 near-identical. Cα-RMSD (Å): average backbone distance after best-fit superposition — lower is better (under 2 Å is excellent). lDDT (0–1): local accuracy measured without superposition — above 0.8 is good. Each bar counts how many structures fall in that range.

Take-home: median TM-score 0.938 — most predictions match the experimental fold well, with a long tail that do not.

Read moreShow less — how each metric is calculated

TM-score: overall shape match, 0–1 (above 0.5 = same fold, above 0.9 near-identical), length-normalised. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) with dᵢ the aligned-Cα gap after superposition and d₀ = 1.24(L−15)^⅓ − 1.8. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264.

Cα-RMSD: the average straight-line distance between matching backbone Cα atoms once the two structures are best-fit superposed (Å; lower is better, under ~2 Å excellent). RMSD = √( (1/N) Σᵢ |Pᵢ − (R·Qᵢ + t)|² ), with Pᵢ/Qᵢ the experimental/model Cα coordinates and R,t the rotation and translation from Kabsch superposition.

lDDT: local accuracy with no superposition — the fraction of short-range inter-residue distances the model reproduces, so it is not fooled by a single wrongly-placed domain. lDDT = (1/N) Σᵢ ¼ Σ_t 1[ |d_exp − d_model| < t ] over thresholds t ∈ {0.5, 1, 2, 4} Å and all residue pairs within 15 Å.

Trend over time

The blue line is the mean TM-score of the structures by their deposit month; the red bars count how many were confidently wrong. Binning by deposit date (rather than by when we processed them) gives an even timeline, tracking whether AlphaFold's accuracy on newly-deposited structures is holding steady, improving, or slipping as the PDB keeps growing. Months with fewer than 5 structures are omitted so each point is a meaningful average. A dashed trend line is drawn only if the change over time is statistically significant.

Read moreShow less — how each metric is calculated

Mean TM-score: the month's average shape-match score. TM̄ = (1/M) Σ TM over the M structures deposited that month.

Trend line: a monotonic-trend test over the monthly means — Mann-Kendall (Kendall's τ) for significance, with a robust Theil-Sen slope for the line. Rank-based, so it tolerates the skewed TM distribution and noisy low-count months. Shown only when p < 0.05; otherwise a note reports that no significant trend was found.

Confidently wrong: the count that were both confident and wrong. count( mean pLDDT > 70 AND TM < 0.5 ).

Matched structures

PDB	UniProt	Protein	Method	Å	Deposited	Novelty %	pLDDT	TM	lDDT	GDT_TS	RMSD	FRAUD	Flag
7UCS_A	P50120	Retinol-binding protein 2	X-ray	1.92	2022-03-17	4.50	96.79	0.56	0.94	0.56	20.60	0.85	ok
7UCT_A	P50120	Retinol-binding protein 2	X-ray	2.52	2022-03-17	7.20	96.79	0.54	0.95	0.75	20.52	0.85	ok
7UCV_A	P50120	Retinol-binding protein 2	X-ray	2.19	2022-03-17	4.50	96.79	0.55	0.95	0.94	20.55	0.85	ok
7UD3_A	P50120	Retinol-binding protein 2	X-ray	2.37	2022-03-17	4.50	96.79	0.56	0.95	1.13	20.19	0.84	ok
7UCN_A	P50120	Retinol-binding protein 2	X-ray	1.96	2022-03-16	3.00	96.79	0.56	0.93	2.26	17.97	0.79	ok
8QJJ_A	P10636	Isoform Tau-D of Microtubule-associated pr	EM	3.35	2023-09-13	0.00	67.98	0.24	0.44	0.67	24.07	0.65	ok
8A4F_A	P05112	Interleukin-4	NMR	—	2022-06-11	0.80	92.87	0.55	0.60	36.82	6.04	0.31	ok
8ENP_A	Q05086	Isoform III of Ubiquitin-protein ligase E3	NMR	—	2022-09-30	0.00	71.70	0.58	0.70	22.38	9.61	0.31	ok
8OF0_Q	Q15370	Elongin-B	EM	3.05	2023-03-13	—	92.50	0.70	—	—	—	0.28	ok
8PPL_AR	P08708	40S ribosomal protein S17	EM	2.65	2023-07-07	0.00	86.48	0.61	0.89	34.51	6.58	0.26	ok
8OEW_Q	Q15370	Elongin-B	EM	2.80	2023-03-13	—	92.50	0.75	—	—	—	0.23	ok
8OEV_Q	Q15370	Elongin-B	EM	2.86	2023-03-13	—	92.50	0.75	—	—	—	0.23	ok
8ISS_C	Q9BSV6	tRNA-splicing endonuclease subunit Sen34	EM	3.19	2023-03-21	—	83.56	0.73	—	—	—	0.23	ok
8I9L_D	P01024	C3a anaphylatoxin	EM	3.18	2023-02-07	0.00	69.30	0.64	0.62	33.93	7.29	0.22	ok
8I9S_A	P09471	Guanine nucleotide-binding protein G(o) su	EM	3.26	2023-02-07	—	94.50	0.78	—	—	—	0.21	ok
8JZZ_C	P09471	Guanine nucleotide-binding protein G(o) su	EM	3.31	2023-07-06	—	94.50	0.78	—	—	—	0.21	ok
8I95_A	P09471	Guanine nucleotide-binding protein G(o) su	EM	2.88	2023-02-06	—	94.50	0.78	—	—	—	0.21	ok
8J6D_A	P09471	Guanine nucleotide-binding protein G(o) su	EM	3.10	2023-04-25	—	94.50	0.78	—	—	—	0.21	ok
8I9L_A	P09471	Guanine nucleotide-binding protein G(o) su	EM	3.18	2023-02-07	—	94.50	0.78	—	—	—	0.21	ok
7Y59_W	Q9BUN8	Derlin-1	EM	4.51	2022-06-16	—	80.00	0.74	—	—	—	0.21	ok
8I97_A	P09471	Guanine nucleotide-binding protein G(o) su	EM	3.19	2023-02-06	—	94.50	0.78	—	—	—	0.21	ok
8PPK_R	P08708	40S ribosomal protein S17	EM	2.98	2023-07-07	—	86.25	0.76	—	—	—	0.21	ok
8HQC_B	P09471	Guanine nucleotide-binding protein G(o) su	EM	3.89	2022-12-13	—	94.50	0.78	—	—	—	0.21	ok
8IA2_B	P09471	Guanine nucleotide-binding protein G(o) su	EM	3.21	2023-02-07	—	94.50	0.78	—	—	—	0.20	ok
8PPL_Ah	P62945	60S ribosomal protein L41	EM	2.65	2023-07-07	—	94.31	0.79	—	—	—	0.20	ok
8HPT_B	P09471	Guanine nucleotide-binding protein G(o) su	EM	3.39	2022-12-13	—	94.50	0.79	—	—	—	0.20	ok
8PPL_I5	Q9Y262	Eukaryotic translation initiation factor 3	EM	2.65	2023-07-07	—	68.81	0.71	—	—	—	0.20	ok
8IA2_D	P01031	C5a anaphylatoxin	EM	3.21	2023-02-07	—	81.56	0.78	—	—	—	0.18	ok
8PPL_Ae	P62861	Ubiquitin-like FUBI-ribosomal protein eS30	EM	2.65	2023-07-07	—	91.00	0.81	—	—	—	0.18	ok
8JAV_R	P62877	E3 ubiquitin-protein ligase RBX1, N-termin	EM	3.44	2023-05-07	—	79.25	0.78	—	—	—	0.18	ok
8FE2_I	P61925	cAMP-dependent protein kinase inhibitor al	X-ray	2.34	2022-12-05	0.00	68.36	0.37	0.82	40.00	4.37	0.17	ok
8CGF_A	P05112	Interleukin-4	NMR	—	2023-02-04	—	86.75	0.80	—	—	—	0.17	ok
8JAS_R	P62877	E3 ubiquitin-protein ligase RBX1, N-termin	EM	3.54	2023-05-07	—	79.25	0.79	—	—	—	0.17	ok
8OF0_O	Q15369	Elongin-C	EM	3.05	2023-03-13	—	89.81	0.81	—	—	—	0.17	ok
8FE5_I	P61925	cAMP-dependent protein kinase inhibitor al	X-ray	2.51	2022-12-05	0.00	68.36	0.33	0.81	42.50	4.21	0.17	ok
8JAQ_R	P62877	E3 ubiquitin-protein ligase RBX1, N-termin	EM	3.26	2023-05-06	—	79.25	0.79	—	—	—	0.17	ok
8OF0_M	Q14241	Elongin-A	EM	3.05	2023-03-13	—	57.03	0.71	—	—	—	0.16	ok
8PPL_Ip	P41567	Eukaryotic translation initiation factor 1	EM	2.65	2023-07-07	—	80.50	0.80	—	—	—	0.16	ok
8OEW_O	Q15369	Elongin-C	EM	2.80	2023-03-13	—	89.81	0.82	—	—	—	0.16	ok
8OEV_O	Q15369	Elongin-C	EM	2.86	2023-03-13	—	89.81	0.82	—	—	—	0.16	ok
8PPL_Ix	O15371	Eukaryotic translation initiation factor 3	EM	2.65	2023-07-07	—	82.69	0.81	—	—	—	0.16	ok
8HQC_D	P01031	C5a anaphylatoxin	EM	3.89	2022-12-13	—	81.56	0.81	—	—	—	0.16	ok
8JZZ_D	P01031	C5a anaphylatoxin	EM	3.31	2023-07-06	—	81.56	0.81	—	—	—	0.16	ok
7Y4W_A	P55072	Transitional endoplasmic reticulum ATPase	EM	3.67	2022-06-16	—	82.56	0.82	—	—	—	0.15	ok
8TZR_A	P56704	Protein Wnt-3a	EM	3.50	2023-08-27	—	88.31	0.83	—	—	—	0.15	ok
8TZP_A	O00755	Protein Wnt-7a	EM	3.23	2023-08-27	—	88.50	0.84	—	—	—	0.14	ok
8PPK_e	P62861	Small ribosomal subunit protein eS30	EM	2.98	2023-07-07	—	91.00	0.84	—	—	—	0.14	ok
7Y53_A	P55072	Transitional endoplasmic reticulum ATPase	EM	3.61	2022-06-16	—	82.56	0.83	—	—	—	0.14	ok
8ISS_D	Q7Z6J9	tRNA-splicing endonuclease subunit Sen54	EM	3.19	2023-03-21	—	72.38	0.81	—	—	—	0.14	ok
8FEC_I	P61925	cAMP-dependent protein kinase inhibitor al	X-ray	2.70	2022-12-06	0.00	68.36	0.35	0.83	48.75	3.51	0.14	ok
8TZO_A	O00755	Protein Wnt-7a	EM	3.10	2023-08-27	—	88.50	0.85	—	—	—	0.14	ok
8JAV_C	Q15370	Elongin-B	EM	3.44	2023-05-07	—	92.50	0.86	—	—	—	0.13	ok
8PPL_Ir	P05198	Eukaryotic translation initiation factor 2	EM	2.65	2023-07-07	—	77.81	0.83	—	—	—	0.13	ok
8PPK_h	P62945	60S ribosomal protein L41	EM	2.98	2023-07-07	—	94.31	0.86	—	—	—	0.13	ok
8PPK_f	P62979	Ubiquitin-40S ribosomal protein S27a	EM	2.98	2023-07-07	—	89.56	0.86	—	—	—	0.13	ok
8OEW_M	Q14241	Elongin-A	EM	2.80	2023-03-13	—	57.03	0.78	—	—	—	0.13	ok
8OEV_M	Q14241	Elongin-A	EM	2.86	2023-03-13	—	57.03	0.78	—	—	—	0.13	ok
8PPL_Iq	P47813	Eukaryotic translation initiation factor 1	EM	2.65	2023-07-07	—	77.94	0.85	—	—	—	0.12	ok
8OYP_C	P0CG47	Polyubiquitin-B	X-ray	2.44	2023-05-05	—	93.44	0.88	—	—	—	0.12	ok
8PPL_I3	Q9UBQ5	Eukaryotic translation initiation factor 3	EM	2.65	2023-07-07	—	87.12	0.87	—	—	—	0.11	ok
7Y59_A	P55072	Transitional endoplasmic reticulum ATPase	EM	4.51	2022-06-16	—	82.56	0.87	—	—	—	0.11	ok
8KH5_B	P63092	Guanine nucleotide-binding protein G(s) su	EM	2.83	2023-08-21	—	91.31	0.88	—	—	—	0.11	ok
8OYK_A	Q15468	Isoform 2 of SCL-interrupting locus protei	X-ray	1.90	2023-05-05	—	53.78	0.80	—	—	—	0.11	ok
8ITL_R	P48546	Gastric inhibitory polypeptide receptor	EM	3.23	2023-03-22	—	78.50	0.86	—	—	—	0.11	ok
8I9S_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.26	2023-02-07	—	89.56	0.88	—	—	—	0.11	ok
8ITM_R	P48546	Gastric inhibitory polypeptide receptor	EM	3.13	2023-03-22	—	78.50	0.86	—	—	—	0.11	ok
8PPL_I6	Q7L2H7	Eukaryotic translation initiation factor 3	EM	2.65	2023-07-07	—	55.28	0.81	—	—	—	0.11	ok
8PPL_AP	P62841	40S ribosomal protein S15	EM	2.65	2023-07-07	—	86.44	0.88	—	—	—	0.11	ok
8JUY_A	Q6PL18	ATPase family AAA domain-containing protei	EM	4.34	2023-06-27	—	61.53	0.83	—	—	—	0.11	ok
8JAQ_C	Q15370	Elongin-B	EM	3.26	2023-05-06	—	92.50	0.89	—	—	—	0.10	ok
8CH7_A	P05112	Interleukin-4	NMR	—	2023-02-07	—	86.75	0.88	—	—	—	0.10	ok
8PPL_Af	P62979	Ubiquitin-40S ribosomal protein S27a	EM	2.65	2023-07-07	—	89.56	0.89	—	—	—	0.10	ok
8H43_A	O43189	PHD finger protein 1	X-ray	2.30	2022-10-10	—	71.00	0.86	—	—	—	0.10	ok
8JAS_C	Q15370	Elongin-B	EM	3.54	2023-05-07	—	92.50	0.90	—	—	—	0.10	ok
8IA2_A	P21730	C5a anaphylatoxin chemotactic receptor 1	EM	3.21	2023-02-07	—	85.75	0.89	—	—	—	0.10	ok
8IA2_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.21	2023-02-07	—	89.56	0.90	—	—	—	0.09	ok
8FYJ_Y	P01730	T-cell surface glycoprotein CD4	EM	4.00	2023-01-26	—	85.25	0.89	—	—	—	0.09	ok
7UD1_A	P50120	Retinol-binding protein 2	X-ray	1.32	2022-03-17	—	96.50	0.90	—	—	—	0.09	ok
8PPL_Ac	P62857	40S ribosomal protein S28	EM	2.65	2023-07-07	—	91.00	0.90	—	—	—	0.09	ok
8PPK_c	P62857	40S ribosomal protein S28	EM	2.98	2023-07-07	—	91.00	0.90	—	—	—	0.09	ok
8B82_A	Q14160	Protein scribble homolog	X-ray	2.80	2022-10-04	—	62.53	0.86	—	—	—	0.09	ok
8B8O_A	Q14160	Protein scribble homolog	X-ray	2.90	2022-10-04	—	62.53	0.86	—	—	—	0.09	ok
8JZZ_A	P21730	C5a anaphylatoxin chemotactic receptor 1	EM	3.31	2023-07-06	—	85.75	0.90	—	—	—	0.09	ok
8HPT_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.39	2022-12-13	—	89.56	0.90	—	—	—	0.09	ok
8H3H_A	Q6PL18	ATPase family AAA domain-containing protei	EM	3.15	2022-10-08	—	61.53	0.86	—	—	—	0.08	ok
8PPK_L	P62280	40S ribosomal protein S11	EM	2.98	2023-07-07	—	88.06	0.91	—	—	—	0.08	ok
8JAU_C	Q15370	Elongin-B	EM	3.22	2023-05-07	—	92.50	0.91	—	—	—	0.08	ok
8JAU_D	Q15369	Elongin-C	EM	3.22	2023-05-07	—	89.81	0.91	—	—	—	0.08	ok
8TZR_B	Q5T9L3	Protein wntless homolog	EM	3.50	2023-08-27	—	82.56	0.91	—	—	—	0.08	ok
8TZP_B	Q5T9L3	Protein wntless homolog	EM	3.23	2023-08-27	—	82.56	0.91	—	—	—	0.08	ok
8TZO_B	Q5T9L3	Protein wntless homolog	EM	3.10	2023-08-27	—	82.56	0.91	—	—	—	0.08	ok
8JAL_D	Q15369	Elongin-C	EM	3.30	2023-05-06	—	89.81	0.91	—	—	—	0.08	ok
8JAR_D	Q15369	Elongin-C	EM	3.30	2023-05-07	—	89.81	0.92	—	—	—	0.08	ok
8JAL_C	Q15370	Elongin-B	EM	3.30	2023-05-06	—	92.50	0.92	—	—	—	0.08	ok
8JUZ_A	Q6PL18	ATPase family AAA domain-containing protei	EM	4.29	2023-06-27	—	61.53	0.88	—	—	—	0.07	ok
8JUW_A	Q6PL18	ATPase family AAA domain-containing protei	EM	3.79	2023-06-27	—	61.53	0.88	—	—	—	0.07	ok
8JAV_D	Q15369	Elongin-C	EM	3.44	2023-05-07	—	89.81	0.92	—	—	—	0.07	ok
7UCZ_A	P50120	Retinol-binding protein 2	X-ray	1.08	2022-03-17	—	96.50	0.92	—	—	—	0.07	ok
8EME_A	P00533	Epidermal growth factor receptor	X-ray	3.32	2022-09-27	—	75.94	0.91	—	—	—	0.07	ok
8J6D_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.10	2023-04-25	—	89.56	0.92	—	—	—	0.07	ok
8PPL_Ad	P62273	40S ribosomal protein S29	EM	2.65	2023-07-07	—	93.69	0.93	—	—	—	0.07	ok
8JAR_C	Q15370	Elongin-B	EM	3.30	2023-05-07	—	92.50	0.93	—	—	—	0.07	ok
8PPL_AG	P62753	40S ribosomal protein S6	EM	2.65	2023-07-07	—	94.19	0.93	—	—	—	0.07	ok
8PPK_d	P62273	40S ribosomal protein S29	EM	2.98	2023-07-07	—	93.69	0.93	—	—	—	0.07	ok
7Y53_W	Q9BUN8	Derlin-1	EM	3.61	2022-06-16	—	80.00	0.91	—	—	—	0.07	ok
8TZP_C	O95980	Reversion-inducing cysteine-rich protein w	EM	3.23	2023-08-27	—	81.06	0.92	—	—	—	0.07	ok
8OYL_A	Q15468	SCL-interrupting locus protein	X-ray	1.92	2023-05-05	3.40	81.47	0.65	0.93	78.91	1.75	0.07	ok
8PPK_P	P62841	40S ribosomal protein S15	EM	2.98	2023-07-07	—	86.44	0.92	—	—	—	0.07	ok
8I9A_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.57	2023-02-06	—	89.56	0.93	—	—	—	0.06	ok
8PPL_Is	P20042	Eukaryotic translation initiation factor 2	EM	2.65	2023-07-07	—	64.94	0.90	—	—	—	0.06	ok
7Y4W_W	Q9BUN8	Derlin-1	EM	3.67	2022-06-16	—	80.00	0.92	—	—	—	0.06	ok
8PPL_Iy	Q99613	Eukaryotic translation initiation factor 3	EM	2.65	2023-07-07	—	71.25	0.91	—	—	—	0.06	ok
8PPL_AL	P62280	40S ribosomal protein S11	EM	2.65	2023-07-07	—	88.06	0.93	—	—	—	0.06	ok
8HQC_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.89	2022-12-13	—	89.56	0.93	—	—	—	0.06	ok
8IM2_A	P32754	4-hydroxyphenylpyruvate dioxygenase	X-ray	2.81	2023-03-05	—	95.69	0.94	—	—	—	0.06	ok
8KH5_A	Q9BXC1	Probable G-protein coupled receptor 174	EM	2.83	2023-08-21	—	84.12	0.93	—	—	—	0.06	ok
8PPL_Ab	P42677	40S ribosomal protein S27	EM	2.65	2023-07-07	—	92.44	0.94	—	—	—	0.06	ok
8PPK_b	P42677	40S ribosomal protein S27	EM	2.98	2023-07-07	—	92.44	0.94	—	—	—	0.06	ok
8I95_C	Q16581	C3a anaphylatoxin chemotactic receptor	EM	2.88	2023-02-06	—	68.81	0.92	—	—	—	0.06	ok
8IM3_A	P32754	4-hydroxyphenylpyruvate dioxygenase	X-ray	2.78	2023-03-05	—	95.69	0.94	—	—	—	0.06	ok
8I9S_C	Q16581	C3a anaphylatoxin chemotactic receptor	EM	3.26	2023-02-07	—	68.81	0.92	—	—	—	0.06	ok
8I9A_C	Q16581	C3a anaphylatoxin chemotactic receptor	EM	3.57	2023-02-06	—	68.81	0.92	—	—	—	0.06	ok
8JZZ_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.31	2023-07-06	—	89.56	0.94	—	—	—	0.06	ok
8I97_C	Q16581	C3a anaphylatoxin chemotactic receptor	EM	3.19	2023-02-06	—	68.81	0.92	—	—	—	0.06	ok
8I9L_C	Q16581	C3a anaphylatoxin chemotactic receptor	EM	3.18	2023-02-07	—	68.81	0.92	—	—	—	0.05	ok
8PPK_G	P62753	40S ribosomal protein S6	EM	2.98	2023-07-07	—	94.19	0.94	—	—	—	0.05	ok
8KB5_C	P04908	Histone H2A type 1-B/E	EM	2.26	2023-08-03	—	90.75	0.94	—	—	—	0.05	ok
8KH5_D	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	2.83	2023-08-21	—	89.56	0.94	—	—	—	0.05	ok
8PPK_B	P61247	40S ribosomal protein S3a	EM	2.98	2023-07-07	—	82.94	0.94	—	—	—	0.05	ok
8PPL_Iv	P60228	Eukaryotic translation initiation factor 3	EM	2.65	2023-07-07	—	64.88	0.92	—	—	—	0.05	ok
8J6D_C	Q16581	C3a anaphylatoxin chemotactic receptor	EM	3.10	2023-04-25	—	68.81	0.93	—	—	—	0.05	ok
8PPK_S	P62269	Small ribosomal subunit protein uS13	EM	2.98	2023-07-07	—	88.69	0.94	—	—	—	0.05	ok
8PPK_U	P60866	40S ribosomal protein S20	EM	2.98	2023-07-07	—	85.25	0.94	—	—	—	0.05	ok
8PPK_p	P41567	Eukaryotic translation initiation factor 1	EM	2.98	2023-07-07	—	80.50	0.94	—	—	—	0.05	ok
8PPL_AS	P62269	Small ribosomal subunit protein uS13	EM	2.65	2023-07-07	—	88.69	0.95	—	—	—	0.05	ok
8JAS_D	Q15369	Elongin-C	EM	3.54	2023-05-07	—	89.81	0.95	—	—	—	0.05	ok
8PPL_AU	P60866	40S ribosomal protein S20	EM	2.65	2023-07-07	—	85.25	0.94	—	—	—	0.05	ok
8PPL_AB	P61247	40S ribosomal protein S3a	EM	2.65	2023-07-07	—	82.94	0.94	—	—	—	0.05	ok
8ERD_A	P24941	Cyclin-dependent kinase 2	X-ray	1.33	2022-10-11	—	88.44	0.95	—	—	—	0.05	ok
8OXX_A	Q08188	Protein-glutamine gamma-glutamyltransferas	X-ray	2.50	2023-05-02	—	95.88	0.95	—	—	—	0.05	ok
8I97_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.19	2023-02-06	—	89.56	0.95	—	—	—	0.05	ok
8B87_A	Q14160	Protein scribble homolog	X-ray	2.00	2022-10-04	—	62.53	0.93	—	—	—	0.05	ok
8PPL_I8	O15372	Eukaryotic translation initiation factor 3	EM	2.65	2023-07-07	—	72.69	0.94	—	—	—	0.04	ok
8JAQ_D	Q15369	Elongin-C	EM	3.26	2023-05-06	—	89.81	0.95	—	—	—	0.04	ok
8PPL_AY	P62847	40S ribosomal protein S24	EM	2.65	2023-07-07	—	88.69	0.95	—	—	—	0.04	ok
8PPL_Iu	Q14152	Eukaryotic translation initiation factor 3	EM	2.65	2023-07-07	—	63.94	0.93	—	—	—	0.04	ok
8PPK_Y	P62847	40S ribosomal protein S24	EM	2.98	2023-07-07	—	88.69	0.95	—	—	—	0.04	ok
8GYC_A	P08758	Annexin A5	X-ray	1.80	2022-09-22	—	96.12	0.96	—	—	—	0.04	ok
8PPL_Io	O75821	Eukaryotic translation initiation factor 3	EM	2.65	2023-07-07	—	70.19	0.94	—	—	—	0.04	ok
8I95_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	2.88	2023-02-06	—	89.56	0.96	—	—	—	0.04	ok
8KB5_B	P62805	Histone H4	EM	2.26	2023-08-03	—	89.81	0.96	—	—	—	0.04	ok
8I9L_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.18	2023-02-07	—	89.56	0.96	—	—	—	0.04	ok
8PPL_AI	P62241	40S ribosomal protein S8	EM	2.65	2023-07-07	—	93.00	0.96	—	—	—	0.04	ok
8PPK_I	P62241	40S ribosomal protein S8	EM	2.98	2023-07-07	—	93.00	0.96	—	—	—	0.03	ok
8ERN_A	P24941	Cyclin-dependent kinase 2	X-ray	1.64	2022-10-12	—	88.44	0.96	—	—	—	0.03	ok
8B9T_A	Q14160	Protein scribble homolog	X-ray	2.50	2022-10-07	—	62.53	0.95	—	—	—	0.03	ok
8ISS_A	Q8WW01	tRNA-splicing endonuclease subunit Sen15	EM	3.19	2023-03-21	—	77.06	0.96	—	—	—	0.03	ok
8PPL_AA	P08865	40S ribosomal protein SA	EM	2.65	2023-07-07	—	79.25	0.96	—	—	—	0.03	ok
8PPL_AH	P62081	40S ribosomal protein S7	EM	2.65	2023-07-07	—	86.88	0.96	—	—	—	0.03	ok
8PPK_H	P62081	40S ribosomal protein S7	EM	2.98	2023-07-07	—	86.88	0.96	—	—	—	0.03	ok
8PPK_M	P25398	40S ribosomal protein S12	EM	2.98	2023-07-07	—	80.38	0.96	—	—	—	0.03	ok
8TZS_A	Q5T9L3	Protein wntless homolog	EM	3.84	2023-08-27	—	82.56	0.96	—	—	—	0.03	ok
8JAV_E	Q13617	Cullin-2	EM	3.44	2023-05-07	—	85.75	0.96	—	—	—	0.03	ok
8PPL_AM	P25398	40S ribosomal protein S12	EM	2.65	2023-07-07	—	80.38	0.96	—	—	—	0.03	ok
8FYI_Z	P01730	T-cell surface glycoprotein CD4	EM	3.40	2023-01-26	—	85.25	0.97	—	—	—	0.03	ok
8PPL_Aa	P62854	40S ribosomal protein S26	EM	2.65	2023-07-07	—	85.81	0.97	—	—	—	0.03	ok
8SC4_A	O15245	Solute carrier family 22 member 1	EM	3.46	2023-04-04	—	84.25	0.97	—	—	—	0.03	ok
8PPK_a	P62854	40S ribosomal protein S26	EM	2.98	2023-07-07	—	85.81	0.97	—	—	—	0.03	ok
8PPK_Z	P62851	40S ribosomal protein S25	EM	2.98	2023-07-07	—	73.25	0.96	—	—	—	0.03	ok
8ENJ_A	P53779	Mitogen-activated protein kinase 10	X-ray	2.81	2022-09-30	—	79.31	0.97	—	—	—	0.03	ok
8ISS_B	Q8NCE0	tRNA-splicing endonuclease subunit Sen2	EM	3.19	2023-03-21	—	72.06	0.96	—	—	—	0.03	ok
8SC1_A	O15245	Solute carrier family 22 member 1	EM	2.92	2023-04-04	—	84.25	0.97	—	—	—	0.03	ok
8SC2_A	O15245	Solute carrier family 22 member 1	EM	3.36	2023-04-04	—	84.25	0.97	—	—	—	0.02	ok
8PPK_X	P62266	40S ribosomal protein S23	EM	2.98	2023-07-07	—	94.88	0.97	—	—	—	0.02	ok
8JAS_E	Q13617	Cullin-2	EM	3.54	2023-05-07	—	85.75	0.97	—	—	—	0.02	ok
8TB6_A	P29597	Non-receptor tyrosine-protein kinase TYK2	X-ray	1.96	2023-06-28	—	81.75	0.97	—	—	—	0.02	ok
8PPL_AX	A0A4W2DI10	40S ribosomal protein S23	EM	2.65	2023-07-07	—	92.94	0.97	—	—	—	0.02	ok
8PPL_I4	O00303	Eukaryotic translation initiation factor 3	EM	2.65	2023-07-07	—	73.88	0.97	—	—	—	0.02	ok
8JAQ_E	Q13617	Cullin-2	EM	3.26	2023-05-06	—	85.75	0.97	—	—	—	0.02	ok
8PPK_D	P23396	40S ribosomal protein S3	EM	2.98	2023-07-07	—	91.06	0.97	—	—	—	0.02	ok
8PPL_AZ	P62851	40S ribosomal protein S25	EM	2.65	2023-07-07	—	73.25	0.97	—	—	—	0.02	ok
8QKT_HHH	P06899	Histone H2B type 1-J	X-ray	3.26	2023-09-17	—	85.50	0.97	—	—	—	0.02	ok
8QKT_BBB	A0A8C1JQV0	Histone H4	X-ray	3.26	2023-09-17	—	92.94	0.98	—	—	—	0.02	ok
8QKT_DDD	P06899	Histone H2B type 1-J	X-ray	3.26	2023-09-17	—	85.50	0.97	—	—	—	0.02	ok
8PPL_AD	P23396	40S ribosomal protein S3	EM	2.65	2023-07-07	—	91.06	0.98	—	—	—	0.02	ok
8SC6_A	O15245	Solute carrier family 22 member 1	EM	3.13	2023-04-04	—	84.25	0.97	—	—	—	0.02	ok
8JMX_A	O14965	Aurora kinase A	X-ray	2.95	2023-06-05	—	75.06	0.97	—	—	—	0.02	ok
8PPL_AJ	P46781	40S ribosomal protein S9	EM	2.65	2023-07-07	—	88.12	0.98	—	—	—	0.02	ok
8PPK_A	P08865	40S ribosomal protein SA	EM	2.98	2023-07-07	—	79.25	0.97	—	—	—	0.02	ok
8PPK_V	P63220	40S ribosomal protein S21	EM	2.98	2023-07-07	—	95.50	0.98	—	—	—	0.02	ok
8OF0_S	Q7KZ85	Transcription elongation factor SPT6	EM	3.05	2023-03-13	—	73.06	0.97	—	—	—	0.02	ok
8PPK_J	P46781	40S ribosomal protein S9	EM	2.98	2023-07-07	—	88.12	0.98	—	—	—	0.02	ok
8PPL_AV	P63220	40S ribosomal protein S21	EM	2.65	2023-07-07	—	95.50	0.98	—	—	—	0.02	ok
8JAQ_A	Q92624	Amyloid protein-binding protein 2	EM	3.26	2023-05-06	—	93.38	0.98	—	—	—	0.02	ok
8PPK_F	P46782	40S ribosomal protein S5	EM	2.98	2023-07-07	—	90.44	0.98	—	—	—	0.02	ok
8QKT_CCC	H2QSF5	Histone H2A	X-ray	3.26	2023-09-17	—	89.94	0.98	—	—	—	0.02	ok
8PPL_AQ	P62249	40S ribosomal protein S16	EM	2.65	2023-07-07	—	93.88	0.98	—	—	—	0.02	ok
8PPK_Q	P62249	40S ribosomal protein S16	EM	2.98	2023-07-07	—	93.88	0.98	—	—	—	0.02	ok
8JAS_A	Q92624	Amyloid protein-binding protein 2	EM	3.54	2023-05-07	—	93.38	0.98	—	—	—	0.02	ok
8PPL_AF	P46782	40S ribosomal protein S5	EM	2.65	2023-07-07	—	90.44	0.98	—	—	—	0.02	ok
8SC3_A	O15245	Solute carrier family 22 member 1	EM	3.24	2023-04-04	—	84.25	0.98	—	—	—	0.02	ok
8JAL_A	Q92624	Amyloid protein-binding protein 2	EM	3.30	2023-05-06	—	93.38	0.98	—	—	—	0.02	ok
8PPK_K	P46783	40S ribosomal protein S10	EM	2.98	2023-07-07	—	73.81	0.98	—	—	—	0.02	ok
8JAR_A	Q92624	Amyloid protein-binding protein 2	EM	3.30	2023-05-07	—	93.38	0.98	—	—	—	0.02	ok
8KB5_A	P84243	Histone H3.8	EM	2.26	2023-08-03	—	85.94	0.98	—	—	—	0.02	ok
8JAV_A	Q92624	Amyloid protein-binding protein 2	EM	3.44	2023-05-07	—	93.38	0.98	—	—	—	0.02	ok
8PPK_N	P62277	40S ribosomal protein S13	EM	2.98	2023-07-07	—	94.06	0.98	—	—	—	0.02	ok
8PPL_AN	P62277	40S ribosomal protein S13	EM	2.65	2023-07-07	—	94.06	0.98	—	—	—	0.02	ok
8JAR_E	Q13617	Cullin-2	EM	3.30	2023-05-07	—	85.75	0.98	—	—	—	0.02	ok
8E8P_A	O43708	Maleylacetoacetate isomerase	X-ray	2.28	2022-08-25	—	97.25	0.98	—	—	—	0.02	ok
8PPK_O	P62263	40S ribosomal protein S14	EM	2.98	2023-07-07	—	90.12	0.98	—	—	—	0.02	ok
8JAU_A	Q92624	Amyloid protein-binding protein 2	EM	3.22	2023-05-07	—	93.38	0.98	—	—	—	0.01	ok
8JAU_E	Q13617	Cullin-2	EM	3.22	2023-05-07	—	85.75	0.98	—	—	—	0.01	ok
8PPK_g	P63244	Receptor of activated protein C kinase 1	EM	2.98	2023-07-07	—	92.44	0.98	—	—	—	0.01	ok
8PPK_T	P39019	Small ribosomal subunit protein eS19	EM	2.98	2023-07-07	—	92.00	0.99	—	—	—	0.01	ok
8PPL_AO	P62263	40S ribosomal protein S14	EM	2.65	2023-07-07	—	90.12	0.98	—	—	—	0.01	ok
8JAL_E	Q13617	Cullin-2	EM	3.30	2023-05-06	—	85.75	0.98	—	—	—	0.01	ok
8PXA_AAA	O60885	Bromodomain-containing protein 4	X-ray	1.30	2023-07-22	—	55.31	0.98	—	—	—	0.01	ok
8PPL_Ag	P63244	Receptor of activated protein C kinase 1	EM	2.65	2023-07-07	—	92.44	0.99	—	—	—	0.01	ok
8OEU_S	Q7KZ85	Transcription elongation factor SPT6	EM	3.04	2023-03-13	—	73.06	0.98	—	—	—	0.01	ok
8TZR_C	P27797	Calreticulin	EM	3.50	2023-08-27	—	89.12	0.99	—	—	—	0.01	ok
8EJX_A	P30405	Peptidyl-prolyl cis-trans isomerase F, mit	X-ray	1.65	2022-09-19	—	88.31	0.99	—	—	—	0.01	ok
8OEV_S	Q7KZ85	Transcription elongation factor SPT6	EM	2.86	2023-03-13	—	73.06	0.98	—	—	—	0.01	ok
8QKT_AAA	P68431	Histone H3.1	X-ray	3.26	2023-09-17	—	86.06	0.99	—	—	—	0.01	ok
8IA2_C	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.21	2023-02-07	—	97.06	0.99	—	—	—	0.01	ok
8PPL_AK	P46783	40S ribosomal protein S10	EM	2.65	2023-07-07	—	73.81	0.98	—	—	—	0.01	ok
8PX2_A	P25440	Bromodomain-containing protein 2	X-ray	1.62	2023-07-22	—	64.06	0.98	—	—	—	0.01	ok
8OXY_A	Q08188	Protein-glutamine gamma-glutamyltransferas	X-ray	2.00	2023-05-02	—	95.88	0.99	—	—	—	0.01	ok
8PPL_AT	P39019	Small ribosomal subunit protein eS19	EM	2.65	2023-07-07	—	92.00	0.99	—	—	—	0.01	ok
8PPK_C	P15880	40S ribosomal protein S2	EM	2.98	2023-07-07	—	80.94	0.99	—	—	—	0.01	ok
8TB5_A	P29597	Non-receptor tyrosine-protein kinase TYK2	X-ray	2.32	2023-06-28	—	81.75	0.99	—	—	—	0.01	ok
8PPL_AW	P62244	40S ribosomal protein S15a	EM	2.65	2023-07-07	—	93.06	0.99	—	—	—	0.01	ok
8PPK_W	P62244	40S ribosomal protein S15a	EM	2.98	2023-07-07	—	93.06	0.99	—	—	—	0.01	ok
8J6D_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.10	2023-04-25	—	97.06	0.99	—	—	—	0.01	ok
8I9S_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.26	2023-02-07	—	97.06	0.99	—	—	—	0.01	ok
8QKT_GGG	A0A2Y9FT95	Histone H2A	X-ray	3.26	2023-09-17	—	89.88	0.99	—	—	—	0.01	ok
8I9L_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.18	2023-02-07	—	97.06	0.99	—	—	—	0.01	ok
8G0M_A	P08195	4F2 cell-surface antigen heavy chain	X-ray	2.25	2023-01-31	—	78.69	0.99	—	—	—	0.01	ok
8TZO_C	P27797	Calreticulin	EM	3.10	2023-08-27	—	89.12	0.99	—	—	—	0.01	ok
8HQC_C	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.89	2022-12-13	—	97.06	0.99	—	—	—	0.01	ok
8PPL_AC	P15880	40S ribosomal protein S2	EM	2.65	2023-07-07	—	80.94	0.99	—	—	—	0.01	ok
8JZZ_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.31	2023-07-06	—	97.06	0.99	—	—	—	0.01	ok
8I97_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.19	2023-02-06	—	97.06	0.99	—	—	—	0.01	ok
8I9A_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.57	2023-02-06	—	97.06	0.99	—	—	—	0.01	ok
8HPT_C	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.39	2022-12-13	—	97.06	0.99	—	—	—	0.01	ok
8KB5_D	P06899	Histone H2B type 1-J	EM	2.26	2023-08-03	—	85.50	0.99	—	—	—	0.01	ok
8PX8_A	P25440	Bromodomain-containing protein 2	X-ray	1.60	2023-07-22	—	64.06	0.99	—	—	—	0.01	ok
8I95_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	2.88	2023-02-06	—	97.06	0.99	—	—	—	0.01	ok
8KH5_C	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	2.83	2023-08-21	—	97.06	1.00	—	—	—	0.00	ok
8PPK_E	P62701	40S ribosomal protein S4, X isoform	EM	2.98	2023-07-07	—	95.56	1.00	—	—	—	0.00	ok
8PPL_AE	P62701	40S ribosomal protein S4, X isoform	EM	2.65	2023-07-07	—	95.56	1.00	—	—	—	0.00	ok
8PPL_It	P41091	Eukaryotic translation initiation factor 2	EM	2.65	2023-07-07	—	85.12	1.00	—	—	—	0.00	ok
8OXV_A	Q08188	Protein-glutamine gamma-glutamyltransferas	X-ray	1.80	2023-05-02	—	95.88	1.00	—	—	—	0.00	ok
8OXW_A	Q08188	Protein-glutamine gamma-glutamyltransferas	X-ray	1.70	2023-05-02	—	95.88	1.00	—	—	—	0.00	ok

Click a column header to sort. FRAUD = confidence-weighted error; a structure is flagged confidently wrong when mean pLDDT > 70 yet TM-score < 0.5.