Release week 2023-06-21

Jump to:

150

structures analysed (19 full · 12.7%)

53.3%

confidently wrong

96.0%

novel sequences

32.0%

novel & wrong

0.888

median TM-score

⭐ This week's notable releases

9 novel sequences, 5 confidently wrong. Highlight: Autophagy-related protein 13.

PDB	Protein	Flags	Why it matters
8SQZ_E ↗	Autophagy-related protein 13	novel · 100% confidently wrong	Genuinely unseen sequence (0% identity to anything AlphaFold trained on) — and AlphaFold got the fold wrong despite high confidence.
8SRM_E ↗	Autophagy-related protein 13	novel · 100% confidently wrong	Genuinely unseen sequence (0% identity to anything AlphaFold trained on) — and AlphaFold got the fold wrong despite high confidence.
8SOI_D ↗	Autophagy-related protein 13	novel · 100% confidently wrong	Genuinely unseen sequence (0% identity to anything AlphaFold trained on) — and AlphaFold got the fold wrong despite high confidence.
8CLJ_A ↗	General transcription factor 3C polypeptide 1	novel · 100%	Genuinely unseen sequence (0% identity to anything AlphaFold trained on).
8CLI_A ↗	General transcription factor 3C polypeptide 1	novel · 100%	Genuinely unseen sequence (0% identity to anything AlphaFold trained on).
8P0S_A ↗	Rho-associated protein kinase 1	novel · 100%	Genuinely unseen sequence (0% identity to anything AlphaFold trained on).

see all 150 structures ↓

Zoomed into the red "confidently wrong" box above (pLDDT ≥ 70, TM < 0.5) — the structures AlphaFold got confidently wrong.

The worst offenders ranked, one row per protein (AlphaFold has one model per sequence, so repeat depositions are collapsed — “×N” marks how many structures of that protein exist; the worst is shown). Each row joins what AlphaFold claimed (blue, pLDDT/100) to what the experiment showed (red, TM-score) — the longer the bar, the bigger the miss. Hover a dot to preview its Cα-deviation ribbon; click to open the full entry.

How to read this

Every point is one experimental protein structure. The horizontal axis is AlphaFold's own confidence in its prediction (mean pLDDT, 0–100). The vertical axis is how well that blind prediction actually matches the experiment (TM-score, 0–1; above 0.5 means the same fold, above 0.9 near-identical). Marker size grows with the FRAUD score (confidence-weighted error).

Cutoff: the shaded red box is the "confidently wrong" zone — AlphaFold was confident (mean pLDDT above 70) yet the fold is wrong (TM-score below 0.5). A predictor that had truly solved folding would leave that box empty.

Take-home: 5 of 150 structures (3.3%) are confidently wrong; median TM-score is 0.888.

Read moreShow less — how each metric is calculated

TM-score: how similar the two 3D shapes are overall, 0–1 (a random pair scores ~0.17, an identical fold ~1). Length-normalised so large and small proteins compare fairly. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) — dᵢ is the gap between the i-th aligned Cα atoms after best-fit superposition, and d₀ = 1.24(L−15)^⅓ − 1.8 sets the distance scale for length L. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264; computed with TM-align, doi:10.1093/nar/gki524.

pLDDT: AlphaFold's own confidence in each residue, 0–100 (higher = surer). It is the model predicting its own accuracy before ever seeing the experiment. We plot the per-structure mean. pLDDT = (1/N) Σᵢ pLDDTᵢ, where pLDDTᵢ is the network's confidence output for residue i.

FRAUD score: the headline number — how wrong the prediction was, weighted by how confident AlphaFold was, so a big error it was sure about counts most. FRAUD = (1/N) Σᵢ (pLDDTᵢ/100) · min(Δᵢ,15)/15, where Δᵢ is residue i's Cα distance from the experiment (Å) after superposition, capped at 15 Å. Runs 0 (perfect) to 1.

Novelty: how little AlphaFold had to go on — 100 minus the highest sequence identity between this protein and any structure released before the 2018-04-30 training cutoff. High = genuinely unseen (100% = nothing similar was ever in the training set). novelty = 100 − maxₚ identity(s, p) over pre-cutoff PDB chains p, with identity = 100 × (matching aligned residues)/(alignment length), from an MMseqs2 search.

Homology: the point colour. High novelty (above 70%) flags the sequence as novel (amber) — AlphaFold had no close template; otherwise a pre-cutoff homolog existed (blue) it could have learned the fold from. novel ⇔ novelty > 70%.

What the metrics mean

TM-score (0–1): overall fold match — above 0.5 is the same fold, above 0.9 near-identical. Cα-RMSD (Å): average backbone distance after best-fit superposition — lower is better (under 2 Å is excellent). lDDT (0–1): local accuracy measured without superposition — above 0.8 is good. Each bar counts how many structures fall in that range.

Take-home: median TM-score 0.888 — most predictions match the experimental fold well, with a long tail that do not.

Read moreShow less — how each metric is calculated

TM-score: overall shape match, 0–1 (above 0.5 = same fold, above 0.9 near-identical), length-normalised. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) with dᵢ the aligned-Cα gap after superposition and d₀ = 1.24(L−15)^⅓ − 1.8. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264.

Cα-RMSD: the average straight-line distance between matching backbone Cα atoms once the two structures are best-fit superposed (Å; lower is better, under ~2 Å excellent). RMSD = √( (1/N) Σᵢ |Pᵢ − (R·Qᵢ + t)|² ), with Pᵢ/Qᵢ the experimental/model Cα coordinates and R,t the rotation and translation from Kabsch superposition.

lDDT: local accuracy with no superposition — the fraction of short-range inter-residue distances the model reproduces, so it is not fooled by a single wrongly-placed domain. lDDT = (1/N) Σᵢ ¼ Σ_t 1[ |d_exp − d_model| < t ] over thresholds t ∈ {0.5, 1, 2, 4} Å and all residue pairs within 15 Å.

Trend over time

The blue line is the mean TM-score of the structures by their deposit month; the red bars count how many were confidently wrong. Binning by deposit date (rather than by when we processed them) gives an even timeline, tracking whether AlphaFold's accuracy on newly-deposited structures is holding steady, improving, or slipping as the PDB keeps growing. Months with fewer than 5 structures are omitted so each point is a meaningful average. A dashed trend line is drawn only if the change over time is statistically significant.

Read moreShow less — how each metric is calculated

Mean TM-score: the month's average shape-match score. TM̄ = (1/M) Σ TM over the M structures deposited that month.

Trend line: a monotonic-trend test over the monthly means — Mann-Kendall (Kendall's τ) for significance, with a robust Theil-Sen slope for the line. Rank-based, so it tolerates the skewed TM distribution and noisy low-count months. Shown only when p < 0.05; otherwise a note reports that no significant trend was found.

Confidently wrong: the count that were both confident and wrong. count( mean pLDDT > 70 AND TM < 0.5 ).

Matched structures

PDB	UniProt	Protein	Method	Å	Deposited	Novelty %	pLDDT	TM	lDDT	GDT_TS	RMSD	FRAUD	Flag
8CLJ_A	Q12789	General transcription factor 3C polypeptid	EM	3.20	2023-02-16	100.00 novel	81.12	0.59	0.85	1.34	17.68	0.69	ok
8CLI_A	Q12789	General transcription factor 3C polypeptid	EM	3.20	2023-02-16	100.00 novel	81.12	0.59	0.85	1.34	17.66	0.69	ok
8P0S_A	Q13464	Rho-associated protein kinase 1	X-ray	2.20	2023-05-10	100.00 novel	69.25	0.67	0.82	0.38	33.71	0.67	ok
8FXV_A	P61812	Transforming growth factor beta-2 proprote	X-ray	2.20	2023-01-25	53.90	85.05	0.70	0.75	6.68	19.35	0.59	ok
8FCQ_G	Q9BZV1	UBX domain-containing protein 6	EM	3.93	2022-12-01	63.50	82.33	0.64	0.90	28.59	10.92	0.37	ok
8FCT_G	Q9BZV1	UBX domain-containing protein 6	EM	3.42	2022-12-01	64.80	74.76	0.51	0.91	25.64	6.53	0.30	ok
8SQZ_C	O75385	Serine/threonine-protein kinase ULK1	EM	5.85	2023-05-04	100.00 novel	81.86	0.67	0.55	37.68	6.16	0.24	ok
8JD6_C	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.40	2023-05-12	0.00	97.97	0.32	0.65	43.42	3.89	0.23	wrong
8FXS_A	P61812	Transforming growth factor beta-2 proprote	X-ray	3.15	2023-01-25	—	80.12	0.73	—	—	—	0.22	ok
8FCT_A	P55072	Transitional endoplasmic reticulum ATPase	EM	3.42	2022-12-01	—	82.56	0.74	—	—	—	0.21	ok
8AFZ_C	P11717	Cation-independent mannose-6-phosphate rec	EM	10.00	2022-07-18	100.00 novel	25.86	0.34	0.39	0.00	12.91	0.21	ok
8SQZ_E	O75143	Autophagy-related protein 13	EM	5.85	2023-05-04	100.00 novel	77.54	0.42	0.76	44.44	4.75	0.19	wrong
8FCP_A	P55072	Transitional endoplasmic reticulum ATPase	EM	3.52	2022-12-01	—	82.56	0.77	—	—	—	0.19	ok
8FCR_G	Q9BZV1	UBX domain-containing protein 6	EM	4.12	2022-12-01	—	76.00	0.75	—	—	—	0.19	ok
8FCR_A	P55072	Transitional endoplasmic reticulum ATPase	EM	4.12	2022-12-01	—	82.56	0.77	—	—	—	0.19	ok
8JD3_C	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.30	2023-05-12	0.00	96.11	0.59	0.72	56.94	3.50	0.19	ok
8FCM_G	Q9BZV1	UBX domain-containing protein 6	EM	3.27	2022-12-01	—	76.00	0.75	—	—	—	0.19	ok
8JD3_A	P63096	Guanine nucleotide-binding protein G(i) su	EM	3.30	2023-05-12	—	93.75	0.81	—	—	—	0.18	ok
8ASC_J	Q9BUH6	Protein PAXX	X-ray	2.95	2022-08-19	0.00	71.71	0.26	0.71	42.86	3.98	0.18	wrong
8CLK_E	Q9Y5Q8	General transcription factor 3C polypeptid	EM	3.50	2023-02-16	—	77.44	0.77	—	—	—	0.18	ok
8FCM_A	P55072	Transitional endoplasmic reticulum ATPase	EM	3.27	2022-12-01	—	82.56	0.79	—	—	—	0.17	ok
8FCN_A	P55072	Transitional endoplasmic reticulum ATPase	EM	2.95	2022-12-01	—	82.56	0.79	—	—	—	0.17	ok
8JD5_2	Q14416	Metabotropic glutamate receptor 2	EM	3.60	2023-05-12	—	85.69	0.80	—	—	—	0.17	ok
7QAC_B	P01308	Insulin B chain	X-ray	2.29	2021-11-16	0.00	48.25	0.29	0.48	31.67	6.01	0.17	ok
8J19_A	P63096	Guanine nucleotide-binding protein G(i) su	EM	3.23	2023-04-12	—	93.75	0.82	—	—	—	0.17	ok
8FCL_A	P55072	Transitional endoplasmic reticulum ATPase	EM	3.51	2022-12-01	—	82.56	0.80	—	—	—	0.16	ok
8HMP_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	2.77	2022-12-05	19.80	95.66	0.64	0.91	58.77	2.90	0.16	ok
8JD6_A	P08754	Guanine nucleotide-binding protein G(i) su	EM	3.40	2023-05-12	—	93.81	0.83	—	—	—	0.16	ok
8OUY_B	O43502	DNA repair protein RAD51 homolog 3	EM	3.40	2023-04-25	—	84.38	0.81	—	—	—	0.16	ok
8J1A_A	P63096	Guanine nucleotide-binding protein G(i) su	EM	3.24	2023-04-12	—	93.75	0.83	—	—	—	0.16	ok
8SQZ_A	Q8TDY2	RB1-inducible coiled-coil protein 1	EM	5.85	2023-05-04	—	72.50	0.78	—	—	—	0.16	ok
8OUZ_B	O43502	DNA repair protein RAD51 homolog 3	EM	2.20	2023-04-25	—	84.38	0.81	—	—	—	0.16	ok
8JD5_A	P63096	Guanine nucleotide-binding protein G(i) su	EM	3.60	2023-05-12	—	93.75	0.83	—	—	—	0.16	ok
8SRM_E	O75143	Autophagy-related protein 13	EM	4.46	2023-05-05	100.00 novel	77.54	0.44	0.85	50.56	4.09	0.16	wrong
8SOI_D	O75143	Autophagy-related protein 13	EM	4.20	2023-04-28	100.00 novel	77.19	0.49	0.88	51.09	3.94	0.16	wrong
8FCO_G	Q9BZV1	UBX domain-containing protein 6	EM	3.31	2022-12-01	—	76.00	0.80	—	—	—	0.16	ok
8JD5_C	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.60	2023-05-12	—	89.56	0.83	—	—	—	0.15	ok
8AFZ_B	Q9Y5X3	Sorting nexin-5	EM	10.00	2022-07-18	—	87.00	0.82	—	—	—	0.15	ok
8CLK_A	Q12789	General transcription factor 3C polypeptid	EM	3.50	2023-02-16	—	64.88	0.76	—	—	—	0.15	ok
8FCP_G	Q9BZV1	UBX domain-containing protein 6	EM	3.52	2022-12-01	—	76.00	0.80	—	—	—	0.15	ok
8FCL_G	Q9BZV1	UBX domain-containing protein 6	EM	3.51	2022-12-01	—	76.00	0.80	—	—	—	0.15	ok
8JD6_R	Q14833	Metabotropic glutamate receptor 4	EM	3.40	2023-05-12	—	83.69	0.82	—	—	—	0.15	ok
8E1D_B	O75030	Microphthalmia-associated transcription fa	NMR	—	2022-08-10	100.00 novel	62.94	0.39	0.73	43.38	4.03	0.15	ok
8FAZ_B	O15315	DNA repair protein RAD51 homolog 2	EM	2.30	2022-11-29	—	78.88	0.81	—	—	—	0.15	ok
8DC0_B	P61812	Transforming growth factor beta-2	X-ray	1.93	2022-06-15	—	80.12	0.82	—	—	—	0.15	ok
8FCQ_A	P55072	Transitional endoplasmic reticulum ATPase	EM	3.93	2022-12-01	—	82.56	0.82	—	—	—	0.15	ok
8CLL_A	Q12789	General transcription factor 3C polypeptid	EM	3.40	2023-02-16	—	64.88	0.78	—	—	—	0.14	ok
8H4I_C	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.06	2022-10-10	—	89.56	0.84	—	—	—	0.14	ok
8J18_A	P63096	Guanine nucleotide-binding protein G(i) su	EM	2.89	2023-04-12	—	93.75	0.85	—	—	—	0.14	ok
8FAZ_C	O43502	DNA repair protein RAD51 homolog 3	EM	2.30	2022-11-29	—	84.38	0.83	—	—	—	0.14	ok
8OUY_A	O15315	DNA repair protein RAD51 homolog 2	EM	3.40	2023-04-25	—	78.88	0.82	—	—	—	0.14	ok
8GBJ_B	O15315	DNA repair protein RAD51 homolog 2	EM	3.11	2023-02-26	—	78.88	0.82	—	—	—	0.14	ok
8GBJ_C	O43502	DNA repair protein RAD51 homolog 3	EM	3.11	2023-02-26	—	84.38	0.84	—	—	—	0.14	ok
8FCO_A	P55072	Transitional endoplasmic reticulum ATPase	EM	3.31	2022-12-01	—	82.56	0.83	—	—	—	0.14	ok
8H4L_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.07	2022-10-10	—	89.56	0.85	—	—	—	0.14	ok
8H4K_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.10	2022-10-10	—	89.56	0.85	—	—	—	0.13	ok
8HMP_A	P63092	Guanine nucleotide-binding protein G(s) su	EM	2.77	2022-12-05	—	91.31	0.86	—	—	—	0.13	ok
8OUZ_A	O15315	DNA repair protein RAD51 homolog 2	EM	2.20	2023-04-25	—	78.88	0.83	—	—	—	0.13	ok
8JD3_2	Q14416	Metabotropic glutamate receptor 2	EM	3.30	2023-05-12	—	85.69	0.85	—	—	—	0.13	ok
7QAC_A	P01308	Insulin A chain	X-ray	2.29	2021-11-16	0.00	51.25	0.21	0.51	47.62	4.51	0.13	ok
8OUY_C	O75771	DNA repair protein RAD51 homolog 4	EM	3.40	2023-04-25	—	88.06	0.87	—	—	—	0.12	ok
8OUZ_C	O75771	DNA repair protein RAD51 homolog 4	EM	2.20	2023-04-25	—	88.06	0.87	—	—	—	0.12	ok
8E1D_A	Q09472	Histone acetyltransferase p300	NMR	—	2022-08-10	—	53.25	0.78	—	—	—	0.12	ok
8SRM_A	Q8TDY2	RB1-inducible coiled-coil protein 1	EM	4.46	2023-05-05	—	72.50	0.84	—	—	—	0.11	ok
8AFZ_A	Q13596	Sorting nexin-1	EM	10.00	2022-07-18	—	74.50	0.85	—	—	—	0.11	ok
8CLK_F	Q969F1	General transcription factor 3C polypeptid	EM	3.50	2023-02-16	—	66.25	0.83	—	—	—	0.11	ok
8BTB_A	Q8NF17	FLJ00385 protein (Fragment)	EM	14.00	2022-11-28	—	72.25	0.85	—	—	—	0.11	ok
8HBW_A	P25874	Mitochondrial brown fat uncoupling protein	EM	2.57	2022-10-31	—	76.12	0.86	—	—	—	0.10	ok
8GBJ_D	O75771	DNA repair protein RAD51 homolog 4	EM	3.11	2023-02-26	—	88.06	0.89	—	—	—	0.10	ok
8FAZ_D	O75771	DNA repair protein RAD51 homolog 4	EM	2.30	2022-11-29	—	88.06	0.89	—	—	—	0.10	ok
8ABQ_A	Q13596	Sorting nexin-1	X-ray	2.81	2022-07-04	—	74.50	0.87	—	—	—	0.09	ok
8CLK_D	Q9Y5Q9	General transcription factor 3C polypeptid	EM	3.50	2023-02-16	—	80.25	0.89	—	—	—	0.09	ok
8SOI_A	Q8TDY2	RB1-inducible coiled-coil protein 1	EM	4.20	2023-04-28	—	72.50	0.87	—	—	—	0.09	ok
8SRM_C	O75385	Serine/threonine-protein kinase ULK1	EM	4.46	2023-05-05	—	59.41	0.85	—	—	—	0.09	ok
8BTB_B	Q8NF17	FLJ00385 protein (Fragment)	EM	14.00	2022-11-28	—	72.25	0.88	—	—	—	0.09	ok
8J1N_A	P25874	Mitochondrial brown fat uncoupling protein	EM	2.51	2023-04-13	—	76.12	0.89	—	—	—	0.08	ok
8HBV_A	P25874	Mitochondrial brown fat uncoupling protein	EM	2.51	2022-10-31	—	76.12	0.89	—	—	—	0.08	ok
8J1A_R	Q9NQS5	G-protein coupled receptor 84	EM	3.24	2023-04-12	—	80.69	0.90	—	—	—	0.08	ok
8J18_R	Q9NQS5	G-protein coupled receptor 84	EM	2.89	2023-04-12	—	80.69	0.90	—	—	—	0.08	ok
8IRR_R	P21728	D(1A) dopamine receptor	EM	3.20	2023-03-19	—	72.44	0.89	—	—	—	0.08	ok
8SOI_C	O75385	Serine/threonine-protein kinase ULK1	EM	4.20	2023-04-28	—	59.41	0.87	—	—	—	0.08	ok
8H4K_R	Q5NUL3	Free fatty acid receptor 4	EM	3.10	2022-10-10	—	79.31	0.90	—	—	—	0.08	ok
8J19_R	Q9NQS5	G-protein coupled receptor 84	EM	3.23	2023-04-12	—	80.69	0.91	—	—	—	0.07	ok
8IYS_A	P50148	Guanine nucleotide-binding protein G(q) su	EM	2.95	2023-04-06	—	93.00	0.92	—	—	—	0.07	ok
8JD3_3	Q14832	Metabotropic glutamate receptor 3	EM	3.30	2023-05-12	—	85.31	0.92	—	—	—	0.07	ok
8J18_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	2.89	2023-04-12	—	89.56	0.92	—	—	—	0.07	ok
8H4L_R	Q5NUL3	Free fatty acid receptor 4	EM	3.07	2022-10-10	—	79.31	0.91	—	—	—	0.07	ok
8IYS_R	Q5NUL3	Free fatty acid receptor 4	EM	2.95	2023-04-06	—	79.31	0.91	—	—	—	0.07	ok
8IYS_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	2.95	2023-04-06	—	89.56	0.93	—	—	—	0.07	ok
8HMP_R	Q9Y2T5	G-protein coupled receptor 52	EM	2.77	2022-12-05	—	81.75	0.92	—	—	—	0.07	ok
8J1A_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.24	2023-04-12	—	89.56	0.93	—	—	—	0.06	ok
8JD3_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.30	2023-05-12	—	97.06	0.94	—	—	—	0.06	ok
8IRR_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.20	2023-03-19	—	89.56	0.93	—	—	—	0.06	ok
8J19_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.23	2023-04-12	—	89.56	0.94	—	—	—	0.06	ok
7Y69_A	Q8NBJ9	SID1 transmembrane family member 2	EM	3.21	2022-06-18	—	80.25	0.93	—	—	—	0.05	ok
7Y68_A	Q8NBJ9	SID1 transmembrane family member 2	EM	2.87	2022-06-18	—	80.25	0.93	—	—	—	0.05	ok
7Y63_A	Q8NBJ9	SID1 transmembrane family member 2	EM	3.16	2022-06-18	—	80.25	0.93	—	—	—	0.05	ok
8H4I_R	Q5NUL3	Free fatty acid receptor 4	EM	3.06	2022-10-10	—	79.31	0.93	—	—	—	0.05	ok
8IRU_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.20	2023-03-19	—	89.56	0.94	—	—	—	0.05	ok
8JD5_4	Q14833	Metabotropic glutamate receptor 4	EM	3.60	2023-05-12	—	83.69	0.94	—	—	—	0.05	ok
8OWI_A	Q02224	Centromere-associated protein E	X-ray	2.14	2023-04-28	—	54.44	0.91	—	—	—	0.05	ok
8AZZ_A	P01116	GTPase KRas	X-ray	1.02	2022-09-06	—	91.50	0.95	—	—	—	0.05	ok
8ABQ_C	Q9Y5X3	Sorting nexin-5	X-ray	2.81	2022-07-04	—	87.00	0.95	—	—	—	0.05	ok
8AHC_A	Q9H8M2	Bromodomain-containing protein 9	X-ray	1.50	2022-07-21	—	62.97	0.93	—	—	—	0.05	ok
7TEU_A	O60674	Tyrosine-protein kinase JAK2	X-ray	1.45	2022-01-05	—	86.88	0.95	—	—	—	0.04	ok
8OUY_D	O43543	DNA repair protein XRCC2	EM	3.40	2023-04-25	—	87.12	0.96	—	—	—	0.03	ok
8FCN_G	Q9BZV1	UBX domain-containing protein 6	EM	2.95	2022-12-01	63.50	78.30	0.66	0.98	96.25	0.71	0.03	ok
8OUZ_D	O43543	DNA repair protein XRCC2	EM	2.20	2023-04-25	—	87.12	0.97	—	—	—	0.03	ok
7Y4D_A	Q9Y6W6	Dual specificity protein phosphatase 10	X-ray	2.18	2022-06-14	—	69.19	0.96	—	—	—	0.03	ok
7XTK_A	P41440	Reduced folate transporter	EM	2.89	2022-05-17	—	72.06	0.97	—	—	—	0.02	ok
8FZB_A	Q96G04	Protein-lysine N-methyltransferase EEF2KMT	X-ray	3.35	2023-01-28	—	92.25	0.97	—	—	—	0.02	ok
8FAZ_X	O43543	DNA repair protein XRCC2	EM	2.30	2022-11-29	—	87.12	0.97	—	—	—	0.02	ok
8GBJ_X	O43543	DNA repair protein XRCC2	EM	3.11	2023-02-26	—	87.12	0.98	—	—	—	0.02	ok
8JD5_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.60	2023-05-12	—	97.06	0.98	—	—	—	0.02	ok
8SX4_A	P06730	Eukaryotic translation initiation factor 4	X-ray	1.99	2023-05-19	—	90.94	0.98	—	—	—	0.02	ok
8JD6_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.40	2023-05-12	—	97.06	0.98	—	—	—	0.02	ok
8SLU_A	P54829	Tyrosine-protein phosphatase non-receptor	X-ray	1.84	2023-04-24	—	72.06	0.97	—	—	—	0.02	ok
8G6Z_A	O60674	Tyrosine-protein kinase JAK2	X-ray	2.45	2023-02-16	—	86.88	0.98	—	—	—	0.02	ok
8SLS_A	P54829	Tyrosine-protein phosphatase non-receptor	X-ray	1.71	2023-04-24	—	72.06	0.97	—	—	—	0.02	ok
8SLT_A	P54829	Tyrosine-protein phosphatase non-receptor	X-ray	1.96	2023-04-24	—	72.06	0.98	—	—	—	0.02	ok
8DQT_A	O15530	3-phosphoinositide-dependent protein kinas	X-ray	1.31	2022-07-19	—	78.75	0.98	—	—	—	0.02	ok
8G8O_A	O60674	Tyrosine-protein kinase JAK2	X-ray	2.20	2023-02-18	—	86.88	0.98	—	—	—	0.02	ok
8CLI_B	Q9UKN8	General transcription factor 3C polypeptid	EM	3.20	2023-02-16	—	81.94	0.98	—	—	—	0.02	ok
8CLL_B	Q9UKN8	General transcription factor 3C polypeptid	EM	3.40	2023-02-16	—	81.94	0.98	—	—	—	0.02	ok
8CLJ_B	Q9UKN8	General transcription factor 3C polypeptid	EM	3.20	2023-02-16	—	81.94	0.98	—	—	—	0.02	ok
8ASC_B	P13010	X-ray repair cross-complementing protein 5	X-ray	2.95	2022-08-19	—	83.12	0.98	—	—	—	0.02	ok
8H4I_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.06	2022-10-10	—	97.06	0.99	—	—	—	0.01	ok
8FDU_B	P43034	Platelet-activating factor acetylhydrolase	EM	3.30	2022-12-04	—	90.25	0.98	—	—	—	0.01	ok
8FDT_B	P43034	Platelet-activating factor acetylhydrolase	EM	3.20	2022-12-04	—	90.25	0.98	—	—	—	0.01	ok
8H4L_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.07	2022-10-10	—	97.06	0.99	—	—	—	0.01	ok
8H4K_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.10	2022-10-10	—	97.06	0.99	—	—	—	0.01	ok
8G8X_A	O60674	Tyrosine-protein kinase JAK2	X-ray	1.97	2023-02-20	—	86.88	0.99	—	—	—	0.01	ok
8ASC_A	P12956	X-ray repair cross-complementing protein 6	X-ray	2.95	2022-08-19	—	84.44	0.99	—	—	—	0.01	ok
7Y4B_A	Q9Y6W6	Dual specificity protein phosphatase 10	X-ray	1.86	2022-06-14	—	69.19	0.99	—	—	—	0.01	ok
8IYS_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	2.95	2023-04-06	—	97.06	0.99	—	—	—	0.01	ok
8HMP_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	2.77	2022-12-05	—	97.06	0.99	—	—	—	0.01	ok
8CLL_C	Q8WUA4	General transcription factor 3C polypeptid	EM	3.40	2023-02-16	—	72.44	0.99	—	—	—	0.01	ok
8IRR_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.20	2023-03-19	—	97.06	0.99	—	—	—	0.01	ok
7Y4E_A	Q9Y6W6	Dual specificity protein phosphatase 10	X-ray	1.93	2022-06-14	—	69.19	0.99	—	—	—	0.01	ok
8AEN_A	P22303	Acetylcholinesterase	X-ray	3.01	2022-07-13	—	92.94	0.99	—	—	—	0.01	ok
8CLJ_C	Q8WUA4	General transcription factor 3C polypeptid	EM	3.20	2023-02-16	—	72.44	0.99	—	—	—	0.01	ok
8CLI_C	Q8WUA4	General transcription factor 3C polypeptid	EM	3.20	2023-02-16	—	72.44	0.99	—	—	—	0.01	ok
7Y4C_A	Q9Y6W6	Dual specificity protein phosphatase 10	X-ray	1.87	2022-06-14	—	69.19	0.99	—	—	—	0.01	ok
8IRU_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.20	2023-03-19	—	97.06	0.99	—	—	—	0.01	ok
8J18_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	2.89	2023-04-12	—	97.06	0.99	—	—	—	0.01	ok
8J1A_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.24	2023-04-12	—	97.06	0.99	—	—	—	0.01	ok
8J19_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.23	2023-04-12	—	97.06	1.00	—	—	—	0.00	ok
8P06_A	P68400	Casein kinase II subunit alpha	X-ray	2.40	2023-05-09	—	88.94	1.00	—	—	—	0.00	ok
8CR0_X	P00918	Carbonic anhydrase 2	X-ray	1.22	2023-03-07	—	97.38	1.00	—	—	—	0.00	ok
8GCL_A	P41181	Aquaporin-2	EM	2.89	2023-03-02	—	91.75	1.00	—	—	—	0.00	ok

Click a column header to sort. FRAUD = confidence-weighted error; a structure is flagged confidently wrong when mean pLDDT > 70 yet TM-score < 0.5.