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New PDB Depositions vs. Their Blind AlphaFold Predictions — A Running Test of “Is Folding Solved?”

Release week 2023-02-08

323
structures analysed (10 full · 3.1%)
00.0%
confidently wrong
00.0%
novel sequences
00.0%
novel & wrong
0.92
median TM-score

Zoomed into the red "confidently wrong" box above (pLDDT ≥ 70, TM < 0.5) — the structures AlphaFold got confidently wrong.

How to read this

Every point is one experimental protein structure. The horizontal axis is AlphaFold's own confidence in its prediction (mean pLDDT, 0–100). The vertical axis is how well that blind prediction actually matches the experiment (TM-score, 0–1; above 0.5 means the same fold, above 0.9 near-identical). Marker size grows with the FRAUD score (confidence-weighted error).

Cutoff: the shaded red box is the "confidently wrong" zone — AlphaFold was confident (mean pLDDT above 70) yet the fold is wrong (TM-score below 0.5). A predictor that had truly solved folding would leave that box empty.

Take-home: 0 of 323 structures (0.0%) are confidently wrong; median TM-score is 0.92.

Read moreShow less — how each metric is calculated

TM-score: how similar the two 3D shapes are overall, 0–1 (a random pair scores ~0.17, an identical fold ~1). Length-normalised so large and small proteins compare fairly. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) — dᵢ is the gap between the i-th aligned Cα atoms after best-fit superposition, and d₀ = 1.24(L−15)^⅓ − 1.8 sets the distance scale for length L. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264; computed with TM-align, doi:10.1093/nar/gki524.

pLDDT: AlphaFold's own confidence in each residue, 0–100 (higher = surer). It is the model predicting its own accuracy before ever seeing the experiment. We plot the per-structure mean. pLDDT = (1/N) Σᵢ pLDDTᵢ, where pLDDTᵢ is the network's confidence output for residue i.

FRAUD score: the headline number — how wrong the prediction was, weighted by how confident AlphaFold was, so a big error it was sure about counts most. FRAUD = (1/N) Σᵢ (pLDDTᵢ/100) · min(Δᵢ,15)/15, where Δᵢ is residue i's Cα distance from the experiment (Å) after superposition, capped at 15 Å. Runs 0 (perfect) to 1.

Novelty: how little AlphaFold had to go on — 100 minus the highest sequence identity between this protein and any structure released before the 2018-04-30 training cutoff. High = genuinely unseen (100% = nothing similar was ever in the training set). novelty = 100 − maxₚ identity(s, p) over pre-cutoff PDB chains p, with identity = 100 × (matching aligned residues)/(alignment length), from an MMseqs2 search.

Homology: the point colour. High novelty (above 70%) flags the sequence as novel (amber) — AlphaFold had no close template; otherwise a pre-cutoff homolog existed (blue) it could have learned the fold from. novel ⇔ novelty > 70%.

What the metrics mean

TM-score (0–1): overall fold match — above 0.5 is the same fold, above 0.9 near-identical. Cα-RMSD (Å): average backbone distance after best-fit superposition — lower is better (under 2 Å is excellent). lDDT (0–1): local accuracy measured without superposition — above 0.8 is good. Each bar counts how many structures fall in that range.

Take-home: median TM-score 0.92 — most predictions match the experimental fold well, with a long tail that do not.

Read moreShow less — how each metric is calculated

TM-score: overall shape match, 0–1 (above 0.5 = same fold, above 0.9 near-identical), length-normalised. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) with dᵢ the aligned-Cα gap after superposition and d₀ = 1.24(L−15)^⅓ − 1.8. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264.

Cα-RMSD: the average straight-line distance between matching backbone Cα atoms once the two structures are best-fit superposed (Å; lower is better, under ~2 Å excellent). RMSD = √( (1/N) Σᵢ |Pᵢ − (R·Qᵢ + t)|² ), with Pᵢ/Qᵢ the experimental/model Cα coordinates and R,t the rotation and translation from Kabsch superposition.

lDDT: local accuracy with no superposition — the fraction of short-range inter-residue distances the model reproduces, so it is not fooled by a single wrongly-placed domain. lDDT = (1/N) Σᵢ ¼ Σ_t 1[ |d_exp − d_model| < t ] over thresholds t ∈ {0.5, 1, 2, 4} Å and all residue pairs within 15 Å.

Trend over time

The blue line is the mean TM-score of the structures by their deposit month; the red bars count how many were confidently wrong. Binning by deposit date (rather than by when we processed them) gives an even timeline, tracking whether AlphaFold's accuracy on newly-deposited structures is holding steady, improving, or slipping as the PDB keeps growing. Months with fewer than 5 structures are omitted so each point is a meaningful average. A dashed trend line is drawn only if the change over time is statistically significant.

Read moreShow less — how each metric is calculated

Mean TM-score: the month's average shape-match score. TM̄ = (1/M) Σ TM over the M structures deposited that month.

Trend line: a monotonic-trend test over the monthly means — Mann-Kendall (Kendall's τ) for significance, with a robust Theil-Sen slope for the line. Rank-based, so it tolerates the skewed TM distribution and noisy low-count months. Shown only when p < 0.05; otherwise a note reports that no significant trend was found.

Confidently wrong: the count that were both confident and wrong. count( mean pLDDT > 70 AND TM < 0.5 ).

Matched structures

PDBUniProtProteinMethodÅDeposited Novelty %pLDDTTMlDDTGDT_TSRMSDFRAUDFlag
8HGP_A P00533 Epidermal growth factor receptor EM 4.53 2022-11-15 0.20 92.03 0.57 0.81 4.23 19.82 0.76 ok
8HGO_A P00533 Epidermal growth factor receptor EM 3.31 2022-11-15 0.20 92.03 0.57 0.84 4.27 19.66 0.76 ok
7QYB_e P60896 26S proteasome complex subunit SEM1 EM 4.10 2022-01-27 69.50 0.26 0.51 ok
7QXW_e P60896 26S proteasome complex subunit SEM1 EM 4.10 2022-01-27 69.50 0.29 0.49 ok
7QXP_e P60896 26S proteasome complex subunit SEM1 EM 3.60 2022-01-26 69.50 0.31 0.48 ok
7QXU_e P60896 26S proteasome complex subunit SEM1 EM 4.30 2022-01-27 69.50 0.31 0.48 ok
7QXN_e P60896 26S proteasome complex subunit SEM1 EM 3.70 2022-01-26 69.50 0.32 0.47 ok
8EQU_C P07602 Saposin-A EM 2.80 2022-10-09 0.00 87.17 0.56 0.80 17.81 9.20 0.47 ok
7QYA_e P60896 26S proteasome complex subunit SEM1 EM 4.80 2022-01-27 69.50 0.33 0.47 ok
7QXX_e P60896 26S proteasome complex subunit SEM1 EM 4.40 2022-01-27 69.50 0.34 0.46 ok
7QY7_e P60896 26S proteasome complex subunit SEM1 EM 4.70 2022-01-27 69.50 0.34 0.46 ok
7W1Y_5 P33992 DNA replication licensing factor MCM5 EM 2.59 2021-11-21 52.90 78.87 0.68 0.80 17.61 10.23 0.41 ok
8A6I_A Q13148 TAR DNA-binding protein 43 NMR 2022-06-17 0.00 46.01 0.25 0.65 6.25 18.36 0.33 ok
7QXX_C P62195 26S proteasome regulatory subunit 8 EM 4.40 2022-01-27 82.12 0.60 0.32 ok
7QXW_C P62195 Isoform 2 of 26S proteasome regulatory sub EM 4.10 2022-01-27 82.12 0.61 0.32 ok
7QXN_C P62195 Isoform 2 of 26S proteasome regulatory sub EM 3.70 2022-01-26 82.12 0.61 0.32 ok
7QYA_C P62195 Isoform 2 of 26S proteasome regulatory sub EM 4.80 2022-01-27 82.12 0.62 0.31 ok
7QXP_C P62195 Isoform 2 of 26S proteasome regulatory sub EM 3.60 2022-01-26 82.12 0.63 0.31 ok
7QXU_C P62195 26S proteasome regulatory subunit 8 EM 4.30 2022-01-27 82.12 0.63 0.31 ok
8EQS_C P02647 Apolipoprotein A-I EM 3.10 2022-10-09 0.00 70.89 0.63 0.83 30.56 6.50 0.27 ok
8B9Q_A P05067 Amyloid-beta A4 protein NMR 2022-10-06 0.00 33.36 0.26 0.23 4.35 13.54 0.25 ok
7QY7_A P35998 26S protease regulatory subunit 7 EM 4.70 2022-01-27 80.56 0.71 0.23 ok
7W1Y_2 P49736 DNA replication licensing factor MCM2 EM 2.59 2021-11-21 76.25 0.71 0.22 ok
7QYB_A P35998 26S protease regulatory subunit 7 EM 4.10 2022-01-27 80.56 0.72 0.22 ok
7QYB_E P62333 26S proteasome regulatory subunit 10B EM 4.10 2022-01-27 86.88 0.75 0.22 ok
7QYB_C P62195 Isoform 2 of 26S proteasome regulatory sub EM 4.10 2022-01-27 82.12 0.74 0.21 ok
7R5X_A Q9H2K2 Poly [ADP-ribose] polymerase tankyrase-2 X-ray 2.05 2022-02-11 83.81 0.75 0.21 ok
7QYB_F P17980 26S protease regulatory subunit 6A EM 4.10 2022-01-27 80.62 0.75 0.20 ok
7QY7_X O00231 26S proteasome non-ATPase regulatory subun EM 4.70 2022-01-27 82.69 0.76 0.20 ok
7QY7_C P62195 PSMC5 isoform 15 EM 4.70 2022-01-27 82.12 0.76 0.19 ok
7QYB_D P43686 26S protease regulatory subunit 6B EM 4.10 2022-01-27 80.12 0.76 0.19 ok
7Z2M_G Q16552 Interleukin-17A X-ray 1.90 2022-02-28 84.31 0.77 0.19 ok
7QXX_D P43686 26S protease regulatory subunit 6B EM 4.40 2022-01-27 80.12 0.76 0.19 ok
7QXN_D P43686 26S protease regulatory subunit 6B EM 3.70 2022-01-26 80.12 0.77 0.19 ok
7QXU_D P43686 26S protease regulatory subunit 6B EM 4.30 2022-01-27 80.12 0.77 0.18 ok
7W1Y_3 P25205 Isoform 2 of DNA replication licensing fac EM 2.59 2021-11-21 74.12 0.75 0.18 ok
7QXP_D P43686 26S protease regulatory subunit 6B EM 3.60 2022-01-26 80.12 0.77 0.18 ok
7QXW_B P62191 26S proteasome regulatory subunit 4 EM 4.10 2022-01-27 77.81 0.77 0.18 ok
7QXP_Z P51665 26S proteasome non-ATPase regulatory subun EM 3.60 2022-01-26 83.12 0.79 0.18 ok
7QY7_D P43686 26S protease regulatory subunit 6B EM 4.70 2022-01-27 80.12 0.78 0.18 ok
7QXN_Z P51665 26S proteasome non-ATPase regulatory subun EM 3.70 2022-01-26 83.12 0.79 0.17 ok
7QXU_V O43242 26S proteasome non-ATPase regulatory subun EM 4.30 2022-01-27 72.56 0.76 0.17 ok
7QXX_Z P51665 26S proteasome non-ATPase regulatory subun EM 4.40 2022-01-27 83.12 0.79 0.17 ok
7QXP_V O43242 26S proteasome non-ATPase regulatory subun EM 3.60 2022-01-26 72.56 0.77 0.17 ok
7QXX_V O43242 26S proteasome non-ATPase regulatory subun EM 4.40 2022-01-27 72.56 0.77 0.17 ok
7QXP_B P62191 26S protease regulatory subunit 4 EM 3.60 2022-01-26 77.81 0.78 0.17 ok
7QY7_Z P51665 26S proteasome non-ATPase regulatory subun EM 4.70 2022-01-27 83.12 0.80 0.17 ok
7QXU_B P62191 26S proteasome regulatory subunit 4 EM 4.30 2022-01-27 77.81 0.78 0.17 ok
7QXN_V O43242 26S proteasome non-ATPase regulatory subun EM 3.70 2022-01-26 72.56 0.77 0.17 ok
7QXU_Z P51665 26S proteasome non-ATPase regulatory subun EM 4.30 2022-01-27 83.12 0.80 0.17 ok
7QXX_B P62191 26S proteasome regulatory subunit 4 EM 4.40 2022-01-27 77.81 0.79 0.17 ok
7QXN_B P62191 26S protease regulatory subunit 4 EM 3.70 2022-01-26 77.81 0.79 0.17 ok
7QXW_V O43242 26S proteasome non-ATPase regulatory subun EM 4.10 2022-01-27 72.56 0.77 0.17 ok
7QYB_V O43242 26S proteasome non-ATPase regulatory subun EM 4.10 2022-01-27 72.56 0.77 0.16 ok
7QYA_D P43686 26S protease regulatory subunit 6B EM 4.80 2022-01-27 80.12 0.80 0.16 ok
7QXW_D P43686 26S protease regulatory subunit 6B EM 4.10 2022-01-27 80.12 0.80 0.16 ok
7UXA_A Q9BSV6 tRNA-splicing endonuclease subunit Sen34 EM 3.28 2022-05-05 83.56 0.81 0.16 ok
7QY7_V O43242 26S proteasome non-ATPase regulatory subun EM 4.70 2022-01-27 72.56 0.78 0.16 ok
7QXW_Z P51665 26S proteasome non-ATPase regulatory subun EM 4.10 2022-01-27 83.12 0.82 0.15 ok
8E3E_A O95365 Zinc finger and BTB domain-containing prot X-ray 2.99 2022-08-17 55.78 0.73 0.15 ok
7QYA_V O43242 26S proteasome non-ATPase regulatory subun EM 4.80 2022-01-27 72.56 0.79 0.15 ok
7QYA_W O00232 26S proteasome non-ATPase regulatory subun EM 4.80 2022-01-27 78.94 0.81 0.15 ok
7QXN_X O00231 26S proteasome non-ATPase regulatory subun EM 3.70 2022-01-26 82.69 0.82 0.15 ok
7QYA_X O00231 26S proteasome non-ATPase regulatory subun EM 4.80 2022-01-27 82.69 0.82 0.15 ok
7W1Y_6 Q14566 DNA replication licensing factor MCM6 EM 2.59 2021-11-21 76.44 0.81 0.15 ok
7QYB_W O00232 26S proteasome non-ATPase regulatory subun EM 4.10 2022-01-27 78.94 0.82 0.14 ok
7QYA_Z P51665 26S proteasome non-ATPase regulatory subun EM 4.80 2022-01-27 83.12 0.83 0.14 ok
8E3D_A O95365 Zinc finger and BTB domain-containing prot X-ray 2.62 2022-08-17 55.78 0.74 0.14 ok
7QXU_d P48556 26S proteasome non-ATPase regulatory subun EM 4.30 2022-01-27 64.88 0.78 0.14 ok
7QXW_A P35998 26S protease regulatory subunit 7 EM 4.10 2022-01-27 80.56 0.82 0.14 ok
7QXX_d P48556 26S proteasome non-ATPase regulatory subun EM 4.40 2022-01-27 64.88 0.78 0.14 ok
7QXN_d P48556 26S proteasome non-ATPase regulatory subun EM 3.70 2022-01-26 64.88 0.78 0.14 ok
7QXW_d P48556 26S proteasome non-ATPase regulatory subun EM 4.10 2022-01-27 64.88 0.78 0.14 ok
7QXP_d P48556 26S proteasome non-ATPase regulatory subun EM 3.60 2022-01-26 64.88 0.78 0.14 ok
7QY7_W O00232 26S proteasome non-ATPase regulatory subun EM 4.70 2022-01-27 78.94 0.82 0.14 ok
8H8J_A Q14344 Guanine nucleotide-binding protein subunit EM 3.20 2022-10-23 91.44 0.85 0.14 ok
7QYB_X O00231 26S proteasome non-ATPase regulatory subun EM 4.10 2022-01-27 82.69 0.83 0.14 ok
7QXP_X O00231 26S proteasome non-ATPase regulatory subun EM 3.60 2022-01-26 82.69 0.84 0.13 ok
7QYA_c O00487 26S proteasome non-ATPase regulatory subun EM 4.80 2022-01-27 81.44 0.84 0.13 ok
7QYA_d P48556 26S proteasome non-ATPase regulatory subun EM 4.80 2022-01-27 64.88 0.80 0.13 ok
8HGO_C P01133 Epidermal growth factor EM 3.31 2022-11-15 70.31 0.81 0.13 ok
7PRW_A P04150 Glucocorticoid receptor X-ray 2.50 2021-09-22 59.59 0.78 0.13 ok
7QXU_X O00231 26S proteasome non-ATPase regulatory subun EM 4.30 2022-01-27 82.69 0.84 0.13 ok
7PRV_A P04150 Glucocorticoid receptor X-ray 2.70 2021-09-22 59.59 0.78 0.13 ok
7Q33_A Q14498 RNA-binding protein 39 NMR 2021-10-26 66.81 0.81 0.13 ok
7QXX_X O00231 26S proteasome non-ATPase regulatory subun EM 4.40 2022-01-27 82.69 0.84 0.13 ok
7QY7_d P48556 26S proteasome non-ATPase regulatory subun EM 4.70 2022-01-27 64.88 0.80 0.13 ok
8HGP_C O14944 Proepiregulin EM 4.53 2022-11-15 68.69 0.81 0.13 ok
7QYA_B P62191 26S protease regulatory subunit 4 EM 4.80 2022-01-27 77.81 0.84 0.13 ok
7QYB_c O00487 26S proteasome non-ATPase regulatory subun EM 4.10 2022-01-27 81.44 0.85 0.12 ok
7QYB_d P48556 26S proteasome non-ATPase regulatory subun EM 4.10 2022-01-27 64.88 0.81 0.12 ok
7QXW_v O76080 AN1-type zinc finger protein 5 EM 4.10 2022-01-27 71.38 0.82 0.12 ok
7QY7_E P62333 26S proteasome regulatory subunit 10B EM 4.70 2022-01-27 86.88 0.86 0.12 ok
7QXW_X O00231 26S proteasome non-ATPase regulatory subun EM 4.10 2022-01-27 82.69 0.85 0.12 ok
7QY7_c O00487 26S proteasome non-ATPase regulatory subun EM 4.70 2022-01-27 81.44 0.85 0.12 ok
7QY7_F P17980 26S protease regulatory subunit 6A EM 4.70 2022-01-27 80.62 0.86 0.12 ok
7QYB_Z P51665 26S proteasome non-ATPase regulatory subun EM 4.10 2022-01-27 83.12 0.86 0.12 ok
7QYA_A P35998 26S protease regulatory subunit 7 EM 4.80 2022-01-27 80.56 0.86 0.11 ok
7QXW_Y Q15008 26S proteasome non-ATPase regulatory subun EM 4.10 2022-01-27 82.38 0.87 0.11 ok
7QYB_B P62191 26S protease regulatory subunit 4 EM 4.10 2022-01-27 77.81 0.86 0.11 ok
7QXN_W O00232 26S proteasome non-ATPase regulatory subun EM 3.70 2022-01-26 78.94 0.87 0.11 ok
7UXA_D Q7Z6J9 tRNA-splicing endonuclease subunit Sen54 EM 3.28 2022-05-05 72.38 0.85 0.11 ok
8H8J_G P59768 Guanine nucleotide-binding protein G(I)/G( EM 3.20 2022-10-23 89.56 0.88 0.10 ok
7QXX_F P17980 26S protease regulatory subunit 6A EM 4.40 2022-01-27 80.62 0.88 0.10 ok
7QXU_W O00232 26S proteasome non-ATPase regulatory subun EM 4.30 2022-01-27 78.94 0.88 0.10 ok
7QXU_F P17980 26S protease regulatory subunit 6A EM 4.30 2022-01-27 80.62 0.88 0.10 ok
7QXP_W O00232 26S proteasome non-ATPase regulatory subun EM 3.60 2022-01-26 78.94 0.88 0.10 ok
7QXP_F P17980 26S protease regulatory subunit 6A EM 3.60 2022-01-26 80.62 0.88 0.10 ok
7QXU_A P35998 26S protease regulatory subunit 7 EM 4.30 2022-01-27 80.56 0.88 0.10 ok
7QXP_A P35998 26S protease regulatory subunit 7 EM 3.60 2022-01-26 80.56 0.88 0.10 ok
7QY7_a Q9UNM6 26S proteasome non-ATPase regulatory subun EM 4.70 2022-01-27 70.75 0.86 0.10 ok
7QXX_A P35998 26S protease regulatory subunit 7 EM 4.40 2022-01-27 80.56 0.88 0.10 ok
7QYA_Y Q15008 26S proteasome non-ATPase regulatory subun EM 4.80 2022-01-27 82.38 0.88 0.10 ok
7QXU_Y Q15008 26S proteasome non-ATPase regulatory subun EM 4.30 2022-01-27 82.38 0.88 0.10 ok
7QXW_W O00232 26S proteasome non-ATPase regulatory subun EM 4.10 2022-01-27 78.94 0.88 0.09 ok
8FHD_C Q07699 Sodium channel subunit beta-1 EM 3.10 2022-12-14 87.06 0.89 0.09 ok
7QXX_Y Q15008 26S proteasome non-ATPase regulatory subun EM 4.40 2022-01-27 82.38 0.89 0.09 ok
7QXN_A P35998 26S protease regulatory subunit 7 EM 3.70 2022-01-26 80.56 0.89 0.09 ok
7QXN_F P17980 26S protease regulatory subunit 6A EM 3.70 2022-01-26 80.62 0.89 0.09 ok
7QXN_Y Q15008 26S proteasome non-ATPase regulatory subun EM 3.70 2022-01-26 82.38 0.89 0.09 ok
7QXP_Y Q15008 26S proteasome non-ATPase regulatory subun EM 3.60 2022-01-26 82.38 0.89 0.09 ok
7QY7_B P62191 26S protease regulatory subunit 4 EM 4.70 2022-01-27 77.81 0.89 0.09 ok
7QY7_Y Q15008 26S proteasome non-ATPase regulatory subun EM 4.70 2022-01-27 82.38 0.89 0.09 ok
7QYA_a Q9UNM6 26S proteasome non-ATPase regulatory subun EM 4.80 2022-01-27 70.75 0.88 0.09 ok
7QXN_c O00487 26S proteasome non-ATPase regulatory subun EM 3.70 2022-01-26 81.44 0.89 0.09 ok
7W1Y_4 P33991 DNA replication licensing factor MCM4 EM 2.59 2021-11-21 73.56 0.88 0.09 ok
7QXX_c O00487 26S proteasome non-ATPase regulatory subun EM 4.40 2022-01-27 81.44 0.90 0.08 ok
8FWK_A Q9NP58 ATP-binding cassette sub-family B member 6 EM 3.50 2023-01-22 83.06 0.90 0.08 ok
7QY7_b P55036 26S proteasome non-ATPase regulatory subun EM 4.70 2022-01-27 72.06 0.89 0.08 ok
7QXW_f Q13200 26S proteasome non-ATPase regulatory subun EM 4.10 2022-01-27 65.06 0.87 0.08 ok
7QXW_a Q9UNM6 26S proteasome non-ATPase regulatory subun EM 4.10 2022-01-27 70.75 0.88 0.08 ok
7QXP_c O00487 26S proteasome non-ATPase regulatory subun EM 3.60 2022-01-26 81.44 0.90 0.08 ok
7QXU_c O00487 26S proteasome non-ATPase regulatory subun EM 4.30 2022-01-27 81.44 0.90 0.08 ok
7QYB_a Q9UNM6 26S proteasome non-ATPase regulatory subun EM 4.10 2022-01-27 70.75 0.89 0.08 ok
7QYB_Y Q15008 26S proteasome non-ATPase regulatory subun EM 4.10 2022-01-27 82.38 0.90 0.08 ok
7QXW_F P17980 26S protease regulatory subunit 6A EM 4.10 2022-01-27 80.62 0.90 0.08 ok
7QXP_f Q13200 26S proteasome non-ATPase regulatory subun EM 3.60 2022-01-26 65.06 0.88 0.08 ok
7QYA_F P17980 26S protease regulatory subunit 6A EM 4.80 2022-01-27 80.62 0.90 0.08 ok
7QXN_a Q9UNM6 26S proteasome non-ATPase regulatory subun EM 3.70 2022-01-26 70.75 0.89 0.08 ok
7QXU_f Q13200 26S proteasome non-ATPase regulatory subun EM 4.30 2022-01-27 65.06 0.88 0.08 ok
7QXN_f Q13200 26S proteasome non-ATPase regulatory subun EM 3.70 2022-01-26 65.06 0.88 0.08 ok
7QXX_a Q9UNM6 26S proteasome non-ATPase regulatory subun EM 4.40 2022-01-27 70.75 0.89 0.08 ok
7QXX_f Q13200 26S proteasome non-ATPase regulatory subun EM 4.40 2022-01-27 65.06 0.88 0.08 ok
7QXU_a Q9UNM6 26S proteasome non-ATPase regulatory subun EM 4.30 2022-01-27 70.75 0.89 0.08 ok
7W1Y_7 P33993 DNA replication licensing factor MCM7 EM 2.59 2021-11-21 80.44 0.90 0.08 ok
7QYB_f Q13200 26S proteasome non-ATPase regulatory subun EM 4.10 2022-01-27 65.06 0.88 0.08 ok
7QXP_a Q9UNM6 26S proteasome non-ATPase regulatory subun EM 3.60 2022-01-26 70.75 0.89 0.08 ok
8H8J_C Q9HC97 G-protein coupled receptor 35 EM 3.20 2022-10-23 84.38 0.91 0.07 ok
7QXX_W O00232 26S proteasome non-ATPase regulatory subun EM 4.40 2022-01-27 78.94 0.91 0.07 ok
7PRX_B Q9UBK2 Peroxisome proliferator-activated receptor X-ray 2.20 2021-09-22 0.00 53.09 0.39 0.81 65.79 2.66 0.07 ok
7QXN_E P62333 26S proteasome regulatory subunit 10B EM 3.70 2022-01-26 86.88 0.92 0.07 ok
7QXX_E P62333 26S proteasome regulatory subunit 10B EM 4.40 2022-01-27 86.88 0.92 0.07 ok
7QXU_E P62333 26S proteasome regulatory subunit 10B EM 4.30 2022-01-27 86.88 0.92 0.07 ok
7QYA_f Q13200 26S proteasome non-ATPase regulatory subun EM 4.80 2022-01-27 65.06 0.89 0.07 ok
7QY7_f Q13200 26S proteasome non-ATPase regulatory subun EM 4.70 2022-01-27 65.06 0.89 0.07 ok
7QXP_E P62333 26S proteasome regulatory subunit 10B EM 3.60 2022-01-26 86.88 0.92 0.07 ok
7QXX_b P55036 26S proteasome non-ATPase regulatory subun EM 4.40 2022-01-27 72.06 0.90 0.07 ok
7QXU_b P55036 26S proteasome non-ATPase regulatory subun EM 4.30 2022-01-27 72.06 0.91 0.07 ok
7R5X_AAA Q9H2K2 Poly [ADP-ribose] polymerase tankyrase-2 X-ray 2.05 2022-02-11 83.81 0.92 0.07 ok
7QY7_H P25787 Proteasome subunit alpha type-2 EM 4.70 2022-01-27 94.75 0.94 0.06 ok
7QXP_b P55036 26S proteasome non-ATPase regulatory subun EM 3.60 2022-01-26 72.06 0.92 0.06 ok
7QXU_J O14818 Proteasome subunit alpha type-7 EM 4.30 2022-01-27 94.38 0.94 0.06 ok
7QXN_b P55036 26S proteasome non-ATPase regulatory subun EM 3.70 2022-01-26 72.06 0.92 0.06 ok
7QXW_c O00487 26S proteasome non-ATPase regulatory subun EM 4.10 2022-01-27 81.44 0.93 0.06 ok
7QYA_b P55036 26S proteasome non-ATPase regulatory subun EM 4.80 2022-01-27 72.06 0.92 0.06 ok
7QXW_J O14818 Proteasome subunit alpha type-7 EM 4.10 2022-01-27 94.38 0.94 0.06 ok
7QXW_H P25787 Proteasome subunit alpha type-2 EM 4.10 2022-01-27 94.75 0.94 0.06 ok
7QXN_J O14818 Proteasome subunit alpha type-7 EM 3.70 2022-01-26 94.38 0.94 0.06 ok
7QY7_J O14818 Proteasome subunit alpha type-7 EM 4.70 2022-01-27 94.38 0.94 0.06 ok
7QYB_U Q99460 26S proteasome non-ATPase regulatory subun EM 4.10 2022-01-27 79.25 0.93 0.05 ok
7QXP_J O14818 Proteasome subunit alpha type-7 EM 3.60 2022-01-26 94.38 0.94 0.05 ok
7QXX_J O14818 Proteasome subunit alpha type-7 EM 4.40 2022-01-27 94.38 0.94 0.05 ok
7QXW_b P55036 26S proteasome non-ATPase regulatory subun EM 4.10 2022-01-27 72.06 0.93 0.05 ok
7QYA_J O14818 Proteasome subunit alpha type-7 EM 4.80 2022-01-27 94.38 0.95 0.05 ok
7QYB_J O14818 Proteasome subunit alpha type-7 EM 4.10 2022-01-27 94.38 0.95 0.05 ok
7QYA_H P25787 Proteasome subunit alpha type-2 EM 4.80 2022-01-27 94.75 0.95 0.05 ok
7QXW_I P25789 Proteasome subunit alpha type-4 EM 4.10 2022-01-27 93.50 0.95 0.05 ok
7QXX_H P25787 Proteasome subunit alpha type-2 EM 4.40 2022-01-27 94.75 0.95 0.05 ok
7QXN_H P25787 Proteasome subunit alpha type-2 EM 3.70 2022-01-26 94.75 0.95 0.05 ok
7QXU_H P25787 Proteasome subunit alpha type-2 EM 4.30 2022-01-27 94.75 0.95 0.05 ok
7QXW_U Q99460 26S proteasome non-ATPase regulatory subun EM 4.10 2022-01-27 79.25 0.94 0.05 ok
7QXP_H P25787 Proteasome subunit alpha type-2 EM 3.60 2022-01-26 94.75 0.95 0.05 ok
7QY7_I P25789 Proteasome subunit alpha type-4 EM 4.70 2022-01-27 93.50 0.95 0.05 ok
7QYA_I P25789 Proteasome subunit alpha type-4 EM 4.80 2022-01-27 93.50 0.95 0.05 ok
7QXX_I P25789 Proteasome subunit alpha type-4 EM 4.40 2022-01-27 93.50 0.95 0.05 ok
7QXN_I P25789 Proteasome subunit alpha type-4 EM 3.70 2022-01-26 93.50 0.95 0.05 ok
7QXU_I P25789 Proteasome subunit alpha type-4 EM 4.30 2022-01-27 93.50 0.95 0.04 ok
7QYA_K P28066 Proteasome subunit alpha type-5 EM 4.80 2022-01-27 94.12 0.95 0.04 ok
7QY7_U Q99460 26S proteasome non-ATPase regulatory subun EM 4.70 2022-01-27 79.25 0.95 0.04 ok
7QXP_I P25789 Proteasome subunit alpha type-4 EM 3.60 2022-01-26 93.50 0.95 0.04 ok
7QY7_K P28066 Proteasome subunit alpha type-5 EM 4.70 2022-01-27 94.12 0.96 0.04 ok
7QYA_E P62333 26S proteasome regulatory subunit 10B EM 4.80 2022-01-27 86.88 0.95 0.04 ok
7QY7_M P25788 Proteasome subunit alpha type-3 EM 4.70 2022-01-27 94.50 0.96 0.04 ok
7QYA_U Q99460 26S proteasome non-ATPase regulatory subun EM 4.80 2022-01-27 79.25 0.95 0.04 ok
7QYA_M P25788 Proteasome subunit alpha type-3 EM 4.80 2022-01-27 94.50 0.96 0.04 ok
7QYB_K P28066 Proteasome subunit alpha type-5 EM 4.10 2022-01-27 94.12 0.96 0.04 ok
7QYB_I P25789 Proteasome subunit alpha type-4 EM 4.10 2022-01-27 93.50 0.96 0.04 ok
7QYB_M P25788 Proteasome subunit alpha type-3 EM 4.10 2022-01-27 94.50 0.96 0.04 ok
7UXA_B Q8WW01 tRNA-splicing endonuclease subunit Sen15 EM 3.28 2022-05-05 77.06 0.95 0.04 ok
7QYB_H P25787 Proteasome subunit alpha type-2 EM 4.10 2022-01-27 94.75 0.96 0.04 ok
7QXW_E P62333 26S proteasome regulatory subunit 10B EM 4.10 2022-01-27 86.88 0.96 0.04 ok
7QYB_b P55036 26S proteasome non-ATPase regulatory subun EM 4.10 2022-01-27 72.06 0.95 0.04 ok
7QXW_M P25788 Proteasome subunit alpha type-3 EM 4.10 2022-01-27 94.50 0.96 0.04 ok
7QXW_K P28066 Proteasome subunit alpha type-5 EM 4.10 2022-01-27 94.12 0.96 0.03 ok
8HGP_B P04626 Receptor tyrosine-protein kinase erbB-2 EM 4.53 2022-11-15 74.00 0.95 0.03 ok
7QXU_U Q99460 26S proteasome non-ATPase regulatory subun EM 4.30 2022-01-27 79.25 0.96 0.03 ok
7QXX_U Q99460 26S proteasome non-ATPase regulatory subun EM 4.40 2022-01-27 79.25 0.96 0.03 ok
7XLQ_A Q15878 Voltage-dependent R-type calcium channel s EM 3.10 2022-04-22 59.94 0.94 0.03 ok
7QYA_Q P49721 Proteasome subunit beta type-2 EM 4.80 2022-01-27 96.69 0.97 0.03 ok
7QXN_K P28066 Proteasome subunit alpha type-5 EM 3.70 2022-01-26 94.12 0.97 0.03 ok
8HGO_B P04626 Receptor tyrosine-protein kinase erbB-2 EM 3.31 2022-11-15 74.00 0.96 0.03 ok
7QXP_U Q99460 26S proteasome non-ATPase regulatory subun EM 3.60 2022-01-26 79.25 0.96 0.03 ok
7QXN_U Q99460 26S proteasome non-ATPase regulatory subun EM 3.70 2022-01-26 79.25 0.96 0.03 ok
7QXX_K P28066 Proteasome subunit alpha type-5 EM 4.40 2022-01-27 94.12 0.97 0.03 ok
7QYA_G P60900 Proteasome subunit alpha type-6 EM 4.80 2022-01-27 96.06 0.97 0.03 ok
7QXU_K P28066 Proteasome subunit alpha type-5 EM 4.30 2022-01-27 94.12 0.97 0.03 ok
7QXP_K P28066 Proteasome subunit alpha type-5 EM 3.60 2022-01-26 94.12 0.97 0.03 ok
7QYA_O Q99436 Proteasome subunit beta type-7 EM 4.80 2022-01-27 90.38 0.97 0.03 ok
7QYB_O Q99436 Proteasome subunit beta type-7 EM 4.10 2022-01-27 90.38 0.97 0.03 ok
7QYB_G P60900 Proteasome subunit alpha type-6 EM 4.10 2022-01-27 96.06 0.97 0.03 ok
7QY7_Q P49721 Proteasome subunit beta type-2 EM 4.70 2022-01-27 96.69 0.97 0.03 ok
8E78_A Q16798 NADP-dependent malic enzyme, mitochondrial EM 2.77 2022-08-23 91.69 0.97 0.03 ok
7UXA_C Q8NCE0 tRNA-splicing endonuclease subunit Sen2 EM 3.28 2022-05-05 72.06 0.96 0.03 ok
8C7W_A Q04771 Activin receptor type I X-ray 2.26 2023-01-17 83.12 0.96 0.03 ok
7QXN_M P25788 Proteasome subunit alpha type-3 EM 3.70 2022-01-26 94.50 0.97 0.03 ok
7QY7_O Q99436 Proteasome subunit beta type-7 EM 4.70 2022-01-27 90.38 0.97 0.03 ok
8EYN_A Q16798 NADP-dependent malic enzyme, mitochondrial X-ray 1.94 2022-10-28 91.69 0.97 0.03 ok
7QXU_M P25788 Proteasome subunit alpha type-3 EM 4.30 2022-01-27 94.50 0.97 0.03 ok
7QY7_G P60900 Proteasome subunit alpha type-6 EM 4.70 2022-01-27 96.06 0.97 0.03 ok
7QXX_M P25788 Proteasome subunit alpha type-3 EM 4.40 2022-01-27 94.50 0.97 0.03 ok
8FZK_A P52292 Importin subunit alpha-1 X-ray 2.10 2023-01-29 86.50 0.97 0.03 ok
7QXP_M P25788 Proteasome subunit alpha type-3 EM 3.60 2022-01-26 94.50 0.97 0.03 ok
7QXU_O Q99436 Proteasome subunit beta type-7 EM 4.30 2022-01-27 90.38 0.97 0.03 ok
7QXX_O Q99436 Proteasome subunit beta type-7 EM 4.40 2022-01-27 90.38 0.97 0.03 ok
7QXW_O Q99436 Proteasome subunit beta type-7 EM 4.10 2022-01-27 90.38 0.97 0.03 ok
7QXN_O Q99436 Proteasome subunit beta type-7 EM 3.70 2022-01-26 90.38 0.97 0.03 ok
7QXP_O Q99436 Proteasome subunit beta type-7 EM 3.60 2022-01-26 90.38 0.97 0.02 ok
8EYO_A Q16798 NADP-dependent malic enzyme, mitochondrial X-ray 2.49 2022-10-28 91.69 0.97 0.02 ok
7PRV_F Q9UBK2 Peroxisome proliferator-activated receptor X-ray 2.70 2021-09-22 0.00 60.77 0.70 0.94 95.83 0.75 0.02 ok
7QXW_G P60900 Proteasome subunit alpha type-6 EM 4.10 2022-01-27 96.06 0.98 0.02 ok
7QXW_Q P49721 Proteasome subunit beta type-2 EM 4.10 2022-01-27 96.69 0.98 0.02 ok
7QYB_Q P49721 Proteasome subunit beta type-2 EM 4.10 2022-01-27 96.69 0.98 0.02 ok
7QXX_Q P49721 Proteasome subunit beta type-2 EM 4.40 2022-01-27 96.69 0.98 0.02 ok
8E76_A Q16798 NADP-dependent malic enzyme, mitochondrial EM 2.51 2022-08-23 91.69 0.98 0.02 ok
8DM6_D Q9BYF1 Processed angiotensin-converting enzyme 2 EM 2.77 2022-07-08 90.69 0.98 0.02 ok
7QYA_N P28072 Proteasome subunit beta type-6 EM 4.80 2022-01-27 88.69 0.98 0.02 ok
8DM5_D Q9BYF1 Processed angiotensin-converting enzyme 2 EM 2.51 2022-07-08 90.69 0.98 0.02 ok
7QY7_P P49720 Proteasome subunit beta type-3 EM 4.70 2022-01-27 97.31 0.98 0.02 ok
7QYA_L P25786 Isoform Long of Proteasome subunit alpha t EM 4.80 2022-01-27 91.88 0.98 0.02 ok
7QXU_G P60900 Proteasome subunit alpha type-6 EM 4.30 2022-01-27 96.06 0.98 0.02 ok
7XLQ_B Q02641 Voltage-dependent L-type calcium channel s EM 3.10 2022-04-22 69.00 0.97 0.02 ok
7QXN_Q P49721 Proteasome subunit beta type-2 EM 3.70 2022-01-26 96.69 0.98 0.02 ok
7QY7_L P25786 Isoform Long of Proteasome subunit alpha t EM 4.70 2022-01-27 91.88 0.98 0.02 ok
7QXX_G P60900 Proteasome subunit alpha type-6 EM 4.40 2022-01-27 96.06 0.98 0.02 ok
7QY7_N P28072 Proteasome subunit beta type-6 EM 4.70 2022-01-27 88.69 0.98 0.02 ok
7QXU_Q P49721 Proteasome subunit beta type-2 EM 4.30 2022-01-27 96.69 0.98 0.02 ok
7QXN_G P60900 Proteasome subunit alpha type-6 EM 3.70 2022-01-26 96.06 0.98 0.02 ok
7QYA_P P49720 Proteasome subunit beta type-3 EM 4.80 2022-01-27 97.31 0.98 0.02 ok
7QXP_Q P49721 Proteasome subunit beta type-2 EM 3.60 2022-01-26 96.69 0.98 0.02 ok
8F7V_A P00747 Plasminogen X-ray 1.65 2022-11-20 82.81 0.98 0.02 ok
7PRW_F Q9UBK2 Peroxisome proliferator-activated receptor X-ray 2.50 2021-09-22 0.00 63.03 0.62 0.98 100.00 0.50 0.02 ok
7QXP_G P60900 Proteasome subunit alpha type-6 EM 3.60 2022-01-26 96.06 0.98 0.02 ok
7QYB_L P25786 Isoform Long of Proteasome subunit alpha t EM 4.10 2022-01-27 91.88 0.98 0.02 ok
7QXW_L P25786 Isoform Long of Proteasome subunit alpha t EM 4.10 2022-01-27 91.88 0.98 0.02 ok
7QXU_L P25786 Isoform Long of Proteasome subunit alpha t EM 4.30 2022-01-27 91.88 0.98 0.02 ok
7QXW_P P49720 Proteasome subunit beta type-3 EM 4.10 2022-01-27 97.31 0.98 0.02 ok
7QXX_N P28072 Proteasome subunit beta type-6 EM 4.40 2022-01-27 88.69 0.98 0.02 ok
7QXX_L P25786 Isoform Long of Proteasome subunit alpha t EM 4.40 2022-01-27 91.88 0.98 0.02 ok
7QXX_P P49720 Proteasome subunit beta type-3 EM 4.40 2022-01-27 97.31 0.98 0.02 ok
7QXN_L P25786 Isoform Long of Proteasome subunit alpha t EM 3.70 2022-01-26 91.88 0.98 0.02 ok
7QYB_N P28072 Proteasome subunit beta type-6 EM 4.10 2022-01-27 88.69 0.98 0.02 ok
7QXN_P P49720 Proteasome subunit beta type-3 EM 3.70 2022-01-26 97.31 0.98 0.02 ok
7QXP_L P25786 Isoform Long of Proteasome subunit alpha t EM 3.60 2022-01-26 91.88 0.98 0.01 ok
7QYB_P P49720 Proteasome subunit beta type-3 EM 4.10 2022-01-27 97.31 0.98 0.01 ok
7QXP_P P49720 Proteasome subunit beta type-3 EM 3.60 2022-01-26 97.31 0.98 0.01 ok
8FHD_A Q9UQD0 Sodium channel protein type 8 subunit alph EM 3.10 2022-12-14 68.38 0.98 0.01 ok
7QXU_P P49720 Proteasome subunit beta type-3 EM 4.30 2022-01-27 97.31 0.99 0.01 ok
8DKG_A P32322 Isoform 3 of Pyrroline-5-carboxylate reduc X-ray 1.85 2022-07-05 89.81 0.98 0.01 ok
7QY7_R P28074 Proteasome subunit beta type-5 EM 4.70 2022-01-27 82.38 0.98 0.01 ok
7QXU_N P28072 Proteasome subunit beta type-6 EM 4.30 2022-01-27 88.69 0.98 0.01 ok
7QYA_R P28074 Proteasome subunit beta type-5 EM 4.80 2022-01-27 82.38 0.98 0.01 ok
7QXW_N P28072 Proteasome subunit beta type-6 EM 4.10 2022-01-27 88.69 0.98 0.01 ok
7QXN_N P28072 Proteasome subunit beta type-6 EM 3.70 2022-01-26 88.69 0.98 0.01 ok
7QXX_R P28074 Proteasome subunit beta type-5 EM 4.40 2022-01-27 82.38 0.98 0.01 ok
7QXN_R P28074 Proteasome subunit beta type-5 EM 3.70 2022-01-26 82.38 0.98 0.01 ok
7QYB_R P28074 Proteasome subunit beta type-5 EM 4.10 2022-01-27 82.38 0.98 0.01 ok
7QXP_N P28072 Proteasome subunit beta type-6 EM 3.60 2022-01-26 88.69 0.98 0.01 ok
8F7U_A P00747 Activation peptide X-ray 1.47 2022-11-20 82.81 0.98 0.01 ok
7QYA_S P20618 Proteasome subunit beta type-1 EM 4.80 2022-01-27 91.38 0.99 0.01 ok
7QXP_R P28074 Proteasome subunit beta type-5 EM 3.60 2022-01-26 82.38 0.98 0.01 ok
7QXW_R P28074 Proteasome subunit beta type-5 EM 4.10 2022-01-27 82.38 0.98 0.01 ok
7QXU_R P28074 Proteasome subunit beta type-5 EM 4.30 2022-01-27 82.38 0.98 0.01 ok
7R5B_A O60885 Bromodomain-containing protein 4 X-ray 1.77 2022-02-10 55.31 0.98 0.01 ok
7XF3_B P61769 Beta-2-microglobulin X-ray 1.91 2022-03-31 94.06 0.99 0.01 ok
7QXX_S P20618 Proteasome subunit beta type-1 EM 4.40 2022-01-27 91.38 0.99 0.01 ok
7YGI_A P04637 Cellular tumor antigen p53 X-ray 2.10 2022-07-11 75.06 0.98 0.01 ok
7QY7_S P20618 Proteasome subunit beta type-1 EM 4.70 2022-01-27 91.38 0.99 0.01 ok
8E8O_A Q16798 NADP-dependent malic enzyme, mitochondrial EM 2.77 2022-08-25 91.69 0.99 0.01 ok
8H1P_A P43351 DNA repair protein RAD52 homolog EM 3.48 2022-10-03 69.62 0.99 0.01 ok
7QXU_S P20618 Proteasome subunit beta type-1 EM 4.30 2022-01-27 91.38 0.99 0.01 ok
8A5N_AAA P02794 Ferritin heavy chain X-ray 1.52 2022-06-15 95.31 0.99 0.01 ok
7QYA_T P28070 Proteasome subunit beta type-4 EM 4.80 2022-01-27 87.44 0.99 0.01 ok
7QY7_T P28070 Proteasome subunit beta type-4 EM 4.70 2022-01-27 87.44 0.99 0.01 ok
7QXX_T P28070 Proteasome subunit beta type-4 EM 4.40 2022-01-27 87.44 0.99 0.01 ok
7QXN_S P20618 Proteasome subunit beta type-1 EM 3.70 2022-01-26 91.38 0.99 0.01 ok
8H8J_B P62873 Guanine nucleotide-binding protein G(I)/G( EM 3.20 2022-10-23 97.06 0.99 0.01 ok
7QXW_S P20618 Proteasome subunit beta type-1 EM 4.10 2022-01-27 91.38 0.99 0.01 ok
7PRX_A P04150 Glucocorticoid receptor X-ray 2.20 2021-09-22 59.59 0.98 0.01 ok
7QXP_S P20618 Proteasome subunit beta type-1 EM 3.60 2022-01-26 91.38 0.99 0.01 ok
7QXW_T P28070 Proteasome subunit beta type-4 EM 4.10 2022-01-27 87.44 0.99 0.01 ok
7QYB_S P20618 Proteasome subunit beta type-1 EM 4.10 2022-01-27 91.38 0.99 0.01 ok
7QXU_T P28070 Proteasome subunit beta type-4 EM 4.30 2022-01-27 87.44 0.99 0.01 ok
7QXN_T P28070 Proteasome subunit beta type-4 EM 3.70 2022-01-26 87.44 0.99 0.01 ok
7QXP_T P28070 Proteasome subunit beta type-4 EM 3.60 2022-01-26 87.44 0.99 0.01 ok
7QYB_T P28070 Proteasome subunit beta type-4 EM 4.10 2022-01-27 87.44 0.99 0.01 ok
7Z4T_I P01584 Interleukin-1 beta X-ray 3.30 2022-03-04 76.25 0.99 0.01 ok
8FZM_A O00629 Importin subunit alpha-3 X-ray 3.00 2023-01-29 86.06 0.99 0.01 ok
7TSW_A P00387 NADH-cytochrome b5 reductase 3 X-ray 2.40 2022-01-31 93.88 0.99 0.01 ok
7XF3_A D9J307 MHC class I antigen X-ray 1.91 2022-03-31 86.31 0.99 0.01 ok
7XLQ_D P54289 Voltage-dependent calcium channel subunit EM 3.10 2022-04-22 86.56 0.99 0.01 ok
8A2L_AAA P02794 Ferritin heavy chain X-ray 2.30 2022-06-03 95.31 1.00 0.00 ok
8DI4_A Q9Y233 cAMP and cAMP-inhibited cGMP 3',5'-cyclic X-ray 2.02 2022-06-28 69.38 0.99 0.00 ok
8A2M_AAA P02794 Ferritin heavy chain, N-terminally process X-ray 1.57 2022-06-03 95.31 1.00 0.00 ok

Click a column header to sort. FRAUD = confidence-weighted error; a structure is flagged confidently wrong when mean pLDDT > 70 yet TM-score < 0.5.