Release week 2022-08-24
⭐ This week's notable releases
2 novel sequences, 1 confidently wrong. Highlight: Galanin.
| PDB | Protein | Flags | Why it matters |
|---|---|---|---|
|
|
Galanin | novel · 100% | Genuinely unseen sequence (0% identity to anything AlphaFold trained on). |
|
|
Insulin-like growth factor 1 receptor | novel · 100% | Genuinely unseen sequence (0% identity to anything AlphaFold trained on). |
|
|
Neurofibromin | confidently wrong | A close pre-cutoff homolog existed (94% identity to 1NF1_1) yet AlphaFold confidently missed the fold. |
Zoomed into the red "confidently wrong" box above (pLDDT ≥ 70, TM < 0.5) — the structures AlphaFold got confidently wrong.
The worst offenders ranked, one row per protein (AlphaFold has one model per sequence, so repeat depositions are collapsed — “×N” marks how many structures of that protein exist; the worst is shown). Each row joins what AlphaFold claimed (blue, pLDDT/100) to what the experiment showed (red, TM-score) — the longer the bar, the bigger the miss. Hover a dot to preview its Cα-deviation ribbon; click to open the full entry.
How to read this
Every point is one experimental protein structure. The horizontal axis is AlphaFold's own confidence in its prediction (mean pLDDT, 0–100). The vertical axis is how well that blind prediction actually matches the experiment (TM-score, 0–1; above 0.5 means the same fold, above 0.9 near-identical). Marker size grows with the FRAUD score (confidence-weighted error).
Cutoff: the shaded red box is the "confidently wrong" zone — AlphaFold was confident (mean pLDDT above 70) yet the fold is wrong (TM-score below 0.5). A predictor that had truly solved folding would leave that box empty.
Take-home: 1 of 130 structures (0.8%) are confidently wrong; median TM-score is 0.931.
Read moreShow less — how each metric is calculated
TM-score: how similar the two 3D shapes are overall, 0–1 (a random pair scores ~0.17, an identical fold ~1). Length-normalised so large and small proteins compare fairly. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) — dᵢ is the gap between the i-th aligned Cα atoms after best-fit superposition, and d₀ = 1.24(L−15)^⅓ − 1.8 sets the distance scale for length L. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264; computed with TM-align, doi:10.1093/nar/gki524.
pLDDT: AlphaFold's own confidence in each residue, 0–100 (higher = surer). It is the model predicting its own accuracy before ever seeing the experiment. We plot the per-structure mean. pLDDT = (1/N) Σᵢ pLDDTᵢ, where pLDDTᵢ is the network's confidence output for residue i.
FRAUD score: the headline number — how wrong the prediction was, weighted by how confident AlphaFold was, so a big error it was sure about counts most. FRAUD = (1/N) Σᵢ (pLDDTᵢ/100) · min(Δᵢ,15)/15, where Δᵢ is residue i's Cα distance from the experiment (Å) after superposition, capped at 15 Å. Runs 0 (perfect) to 1.
Novelty: how little AlphaFold had to go on — 100 minus the highest sequence identity between this protein and any structure released before the 2018-04-30 training cutoff. High = genuinely unseen (100% = nothing similar was ever in the training set). novelty = 100 − maxₚ identity(s, p) over pre-cutoff PDB chains p, with identity = 100 × (matching aligned residues)/(alignment length), from an MMseqs2 search.
Homology: the point colour. High novelty (above 70%) flags the sequence as novel (amber) — AlphaFold had no close template; otherwise a pre-cutoff homolog existed (blue) it could have learned the fold from. novel ⇔ novelty > 70%.
What the metrics mean
TM-score (0–1): overall fold match — above 0.5 is the same fold, above 0.9 near-identical. Cα-RMSD (Å): average backbone distance after best-fit superposition — lower is better (under 2 Å is excellent). lDDT (0–1): local accuracy measured without superposition — above 0.8 is good. Each bar counts how many structures fall in that range.
Take-home: median TM-score 0.931 — most predictions match the experimental fold well, with a long tail that do not.
Read moreShow less — how each metric is calculated
TM-score: overall shape match, 0–1 (above 0.5 = same fold, above 0.9 near-identical), length-normalised. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) with dᵢ the aligned-Cα gap after superposition and d₀ = 1.24(L−15)^⅓ − 1.8. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264.
Cα-RMSD: the average straight-line distance between matching backbone Cα atoms once the two structures are best-fit superposed (Å; lower is better, under ~2 Å excellent). RMSD = √( (1/N) Σᵢ |Pᵢ − (R·Qᵢ + t)|² ), with Pᵢ/Qᵢ the experimental/model Cα coordinates and R,t the rotation and translation from Kabsch superposition.
lDDT: local accuracy with no superposition — the fraction of short-range inter-residue distances the model reproduces, so it is not fooled by a single wrongly-placed domain. lDDT = (1/N) Σᵢ ¼ Σ_t 1[ |d_exp − d_model| < t ] over thresholds t ∈ {0.5, 1, 2, 4} Å and all residue pairs within 15 Å.
Trend over time
The blue line is the mean TM-score of the structures by their deposit month; the red bars count how many were confidently wrong. Binning by deposit date (rather than by when we processed them) gives an even timeline, tracking whether AlphaFold's accuracy on newly-deposited structures is holding steady, improving, or slipping as the PDB keeps growing. Months with fewer than 5 structures are omitted so each point is a meaningful average. A dashed trend line is drawn only if the change over time is statistically significant.
Read moreShow less — how each metric is calculated
Mean TM-score: the month's average shape-match score. TM̄ = (1/M) Σ TM over the M structures deposited that month.
Trend line: a monotonic-trend test over the monthly means — Mann-Kendall (Kendall's τ) for significance, with a robust Theil-Sen slope for the line. Rank-based, so it tolerates the skewed TM distribution and noisy low-count months. Shown only when p < 0.05; otherwise a note reports that no significant trend was found.
Confidently wrong: the count that were both confident and wrong. count( mean pLDDT > 70 AND TM < 0.5 ).
Matched structures
| PDB | UniProt | Protein | Method | Å | Deposited | Novelty % | pLDDT | TM | lDDT | GDT_TS | RMSD | FRAUD | Flag |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 7LV3_A | Q13976 | Isoform Beta of cGMP-dependent protein kin | X-ray | 2.41 | 2021-02-23 | 2.20 | 88.57 | 0.54 | 0.90 | 0.33 | 30.71 | 0.86 | ok |
| 7PGP_F | P21359 | Neurofibromin | EM | 3.10 | 2021-08-15 | 6.30 | 85.86 | 0.49 | 0.30 | 3.00 | 23.00 | 0.75 | wrong |
| 8DPE_A | Q86XP3 | ATP-dependent RNA helicase DDX42 | X-ray | 1.53 | 2022-07-15 | 61.10 | 90.51 | 0.61 | 0.89 | 4.93 | 15.87 | 0.74 | ok |
| 7U4T_P | Q9UI12 | V-type proton ATPase subunit H | EM | 3.60 | 2022-03-01 | 68.80 | 93.33 | 0.69 | 0.71 | 16.86 | 10.06 | 0.51 | ok |
| 7XPY_A | Q93009 | Ubiquitin carboxyl-terminal hydrolase 7 | X-ray | 2.35 | 2022-05-06 | 0.00 | 90.41 | 0.61 | 0.95 | 16.15 | 9.47 | 0.50 | ok |
| 7U4T_K | O75348 | V-type proton ATPase subunit G 1 | EM | 3.60 | 2022-03-01 | 62.20 | 93.65 | 0.50 | 0.96 | 24.56 | 7.48 | 0.40 | ok |
| 7PYV_C | O15205 | UBD | X-ray | 3.27 | 2021-10-11 | 2.70 | 86.78 | 0.59 | 0.77 | 25.00 | 8.14 | 0.38 | ok |
| 7VIJ_A | Q93009 | Ubiquitin carboxyl-terminal hydrolase 7 | X-ray | 2.30 | 2021-09-27 | 0.00 | 90.41 | 0.69 | 0.96 | 24.62 | 7.09 | 0.38 | ok |
| 8DJ4_A | P22466 | Galanin | NMR | — | 2022-06-30 | 100.00 novel | 60.55 | 0.21 | 0.59 | 27.50 | 6.75 | 0.24 | ok |
| 7Z8B_R | P62877 | E3 ubiquitin-protein ligase RBX1 | EM | 2.80 | 2022-03-17 | — | 79.25 | 0.73 | — | — | — | 0.22 | ok |
| 7U4T_V | O75787 | Renin receptor | EM | 3.60 | 2022-03-01 | 0.00 | 85.34 | 0.64 | 0.88 | 46.43 | 4.86 | 0.21 | ok |
| 8DHZ_A | P22466 | Galanin | NMR | — | 2022-06-28 | — | 53.21 | 0.18 | 0.74 | 28.57 | 6.02 | 0.20 | ok |
| 7PDV_A | P52756 | RNA binding motif protein 5 isoform 1 | X-ray | 3.49 | 2021-08-08 | — | 62.38 | 0.71 | — | — | — | 0.18 | ok |
| 7XA3_A | P63096 | Guanine nucleotide-binding protein G(i) su | EM | 2.90 | 2022-03-17 | — | 93.75 | 0.82 | — | — | — | 0.17 | ok |
| 7X9Y_A | P63096 | Guanine nucleotide-binding protein G(i) su | EM | 3.10 | 2022-03-16 | — | 93.75 | 0.82 | — | — | — | 0.17 | ok |
| 7XA3_L | P13500 | C-C motif chemokine 2 | EM | 2.90 | 2022-03-17 | — | 86.94 | 0.83 | — | — | — | 0.15 | ok |
| 7U4T_T | Q6P5S7 | Ribonuclease kappa | EM | 3.60 | 2022-03-01 | — | 66.38 | 0.79 | — | — | — | 0.14 | ok |
| 7RTI_D | Q96JM7 | Lethal(3)malignant brain tumor-like protei | X-ray | 2.05 | 2021-08-13 | — | 46.01 | 0.28 | 0.59 | 36.54 | 4.48 | 0.14 | ok |
| 7U4T_H | P36543 | V-type proton ATPase subunit E 1 | EM | 3.60 | 2022-03-01 | — | 94.94 | 0.86 | — | — | — | 0.14 | ok |
| 7YP7_A | P63092 | Guanine nucleotide-binding protein G(s) su | EM | 3.10 | 2022-08-02 | — | 91.31 | 0.85 | — | — | — | 0.14 | ok |
| 7RTE_D | Q96JM7 | Lethal(3)malignant brain tumor-like protei | X-ray | 2.06 | 2021-08-13 | — | 45.26 | 0.32 | 0.69 | 39.29 | 4.26 | 0.13 | ok |
| 7XZ6_A | P63092 | Guanine nucleotide-binding protein G(s) su | EM | 2.80 | 2022-06-02 | — | 91.31 | 0.87 | — | — | — | 0.12 | ok |
| 7U4T_O | P21283 | V-type proton ATPase subunit C 1 | EM | 3.60 | 2022-03-01 | — | 91.56 | 0.87 | — | — | — | 0.12 | ok |
| 7XZ5_A | P63092 | Guanine nucleotide-binding protein G(s) su | EM | 3.10 | 2022-06-02 | — | 91.31 | 0.87 | — | — | — | 0.12 | ok |
| 8DPF_D | P59768 | Guanine nucleotide-binding protein G(I)/G( | EM | 2.84 | 2022-07-15 | — | 89.56 | 0.86 | — | — | — | 0.12 | ok |
| 7XW5_R | P16473 | Thyrotropin receptor | EM | 2.96 | 2022-05-26 | — | 74.00 | 0.84 | — | — | — | 0.12 | ok |
| 8DPI_D | P59768 | Guanine nucleotide-binding protein G(I)/G( | EM | 3.40 | 2022-07-15 | — | 89.56 | 0.87 | — | — | — | 0.12 | ok |
| 8DPH_D | P59768 | Guanine nucleotide-binding protein G(I)/G( | EM | 3.20 | 2022-07-15 | — | 89.56 | 0.88 | — | — | — | 0.11 | ok |
| 8DPG_D | P59768 | Guanine nucleotide-binding protein G(I)/G( | EM | 3.60 | 2022-07-15 | — | 89.56 | 0.88 | — | — | — | 0.11 | ok |
| 7Z8B_C | Q14999 | Cullin-7 | EM | 2.80 | 2022-03-17 | — | 69.38 | 0.84 | — | — | — | 0.11 | ok |
| 7Z8B_F | Q8N3Y1 | F-box/WD repeat-containing protein 8 | EM | 2.80 | 2022-03-17 | — | 76.81 | 0.86 | — | — | — | 0.10 | ok |
| 7XW5_Y | P01222 | Thyrotropin subunit beta | EM | 2.96 | 2022-05-26 | — | 86.00 | 0.89 | — | — | — | 0.10 | ok |
| 7V7K_C | P15941 | Mucin-1 subunit alpha | X-ray | 2.20 | 2021-08-21 | — | 40.99 | 0.36 | 0.73 | 45.83 | 3.91 | 0.10 | ok |
| 7U4T_S | O15342 | V-type proton ATPase subunit e 1 | EM | 3.60 | 2022-03-01 | — | 92.88 | 0.90 | — | — | — | 0.10 | ok |
| 7XW5_A | P63092 | Guanine nucleotide-binding protein G(s) su | EM | 2.96 | 2022-05-26 | — | 91.31 | 0.89 | — | — | — | 0.10 | ok |
| 7YP7_G | P59768 | Guanine nucleotide-binding protein G(I)/G( | EM | 3.10 | 2022-08-02 | — | 89.56 | 0.89 | — | — | — | 0.10 | ok |
| 7XDT_A | Q8TEQ6 | Gem-associated protein 5 | EM | 3.31 | 2022-03-28 | — | 78.94 | 0.89 | — | — | — | 0.08 | ok |
| 7XGR_A | Q8TEQ6 | Gem-associated protein 5 | EM | 2.60 | 2022-04-06 | — | 78.94 | 0.89 | — | — | — | 0.08 | ok |
| 7XW5_G | P59768 | Guanine nucleotide-binding protein G(I)/G( | EM | 2.96 | 2022-05-26 | — | 89.56 | 0.91 | — | — | — | 0.08 | ok |
| 7X9Y_G | P59768 | Guanine nucleotide-binding protein G(I)/G( | EM | 3.10 | 2022-03-16 | — | 89.56 | 0.91 | — | — | — | 0.08 | ok |
| 7XZ5_G | P59768 | Guanine nucleotide-binding protein G(I)/G( | EM | 3.10 | 2022-06-02 | — | 89.56 | 0.91 | — | — | — | 0.08 | ok |
| 7Z8B_S | P63208 | S-phase kinase-associated protein 1 | EM | 2.80 | 2022-03-17 | — | 90.12 | 0.91 | — | — | — | 0.08 | ok |
| 7X9Y_R | P51677 | C-C chemokine receptor type 3 | EM | 3.10 | 2022-03-16 | — | 83.44 | 0.91 | — | — | — | 0.08 | ok |
| 7XW5_X | P01215 | Glycoprotein hormones alpha chain | EM | 2.96 | 2022-05-26 | — | 91.81 | 0.92 | — | — | — | 0.07 | ok |
| 7XA3_C | P59768 | Guanine nucleotide-binding protein G(I)/G( | EM | 2.90 | 2022-03-17 | — | 89.56 | 0.92 | — | — | — | 0.07 | ok |
| 7RUP_A | Q6Y7W6 | GRB10-interacting GYF protein 2 | X-ray | 1.23 | 2021-08-18 | — | 56.41 | 0.87 | — | — | — | 0.07 | ok |
| 7U4T_R | Q93050 | V-type proton ATPase 116 kDa subunit a iso | EM | 3.60 | 2022-03-01 | — | 84.50 | 0.92 | — | — | — | 0.07 | ok |
| 7XZ6_G | P59768 | Guanine nucleotide-binding protein G(I)/G( | EM | 2.80 | 2022-06-02 | — | 89.56 | 0.93 | — | — | — | 0.06 | ok |
| 7U4T_N | Q16864 | V-type proton ATPase subunit F | EM | 3.60 | 2022-03-01 | — | 86.88 | 0.93 | — | — | — | 0.06 | ok |
| 7U4T_G | Q9Y5K8 | V-type proton ATPase subunit D | EM | 3.60 | 2022-03-01 | — | 86.25 | 0.93 | — | — | — | 0.06 | ok |
| 7SSB_A | Q13976 | cGMP-dependent protein kinase 1 | X-ray | 1.40 | 2021-11-10 | — | 86.69 | 0.93 | — | — | — | 0.06 | ok |
| 7XA3_R | P41597 | Isoform B of C-C chemokine receptor type 2 | EM | 2.90 | 2022-03-17 | — | 77.75 | 0.92 | — | — | — | 0.06 | ok |
| 7U4T_W | Q6P9B6 | MTOR-associated protein MEAK7 | EM | 3.60 | 2022-03-01 | — | 86.31 | 0.93 | — | — | — | 0.06 | ok |
| 7PH8_A | P08069 | Insulin-like growth factor 1 receptor | NMR | — | 2021-08-16 | 100.00 novel | 70.23 | 0.68 | 0.85 | 83.87 | 1.53 | 0.06 | ok |
| 7U4T_Q | P61421 | V-type proton ATPase subunit d 1 | EM | 3.60 | 2022-03-01 | — | 85.88 | 0.93 | — | — | — | 0.06 | ok |
| 7RU6_A | Q13530 | Serine incorporator 3 | EM | 4.40 | 2021-08-16 | — | 76.31 | 0.93 | — | — | — | 0.05 | ok |
| 7U4T_U | Q15904 | V-type proton ATPase subunit S1 | EM | 3.60 | 2022-03-01 | — | 78.81 | 0.93 | — | — | — | 0.05 | ok |
| 7U4T_D | P21281 | V-type proton ATPase subunit B, brain isof | EM | 3.60 | 2022-03-01 | — | 86.00 | 0.94 | — | — | — | 0.05 | ok |
| 8DPF_A | P28335 | 5-hydroxytryptamine receptor 2C | EM | 2.84 | 2022-07-15 | — | 73.56 | 0.93 | — | — | — | 0.05 | ok |
| 7T1L_A | P07332 | Tyrosine-protein kinase Fes/Fps | X-ray | 1.35 | 2021-12-02 | — | 89.38 | 0.94 | — | — | — | 0.05 | ok |
| 8DPI_A | P28335 | 5-hydroxytryptamine receptor 2C | EM | 3.40 | 2022-07-15 | — | 73.56 | 0.93 | — | — | — | 0.05 | ok |
| 7RWF_A | P24941 | Cyclin-dependent kinase 2 | X-ray | 1.50 | 2021-08-19 | — | 88.44 | 0.94 | — | — | — | 0.05 | ok |
| 8DPH_A | P28335 | 5-hydroxytryptamine receptor 2C | EM | 3.20 | 2022-07-15 | — | 73.56 | 0.93 | — | — | — | 0.05 | ok |
| 8DPG_A | P28335 | 5-hydroxytryptamine receptor 2C | EM | 3.60 | 2022-07-15 | — | 73.56 | 0.93 | — | — | — | 0.05 | ok |
| 7PG5_B | P27986 | Phosphatidylinositol 3-kinase regulatory s | X-ray | 2.20 | 2021-08-13 | — | 83.19 | 0.94 | — | — | — | 0.05 | ok |
| 7RUQ_A | O75420 | GRB10-interacting GYF protein 1 | X-ray | 1.79 | 2021-08-18 | — | 55.25 | 0.92 | — | — | — | 0.05 | ok |
| 7PG6_B | P27986 | Phosphatidylinositol 3-kinase regulatory s | X-ray | 2.50 | 2021-08-13 | — | 83.19 | 0.95 | — | — | — | 0.04 | ok |
| 7RV7_A | P41182 | Isoform 2 of B-cell lymphoma 6 protein | X-ray | 1.63 | 2021-08-18 | — | 52.06 | 0.93 | — | — | — | 0.04 | ok |
| 7RV6_A | P41182 | Isoform 2 of B-cell lymphoma 6 protein | X-ray | 1.68 | 2021-08-18 | — | 52.06 | 0.93 | — | — | — | 0.04 | ok |
| 7RV5_A | P41182 | Isoform 2 of B-cell lymphoma 6 protein | X-ray | 2.21 | 2021-08-18 | — | 52.06 | 0.93 | — | — | — | 0.04 | ok |
| 7T1U_A | P12931 | Proto-oncogene tyrosine-protein kinase Src | X-ray | 2.65 | 2021-12-02 | — | 83.44 | 0.96 | — | — | — | 0.04 | ok |
| 7RV3_A | P41182 | Isoform 2 of B-cell lymphoma 6 protein | X-ray | 1.35 | 2021-08-18 | — | 52.06 | 0.93 | — | — | — | 0.04 | ok |
| 7RV8_A | P41182 | Isoform 2 of B-cell lymphoma 6 protein | X-ray | 1.25 | 2021-08-18 | — | 52.06 | 0.93 | — | — | — | 0.04 | ok |
| 7RV4_A | P41182 | Isoform 2 of B-cell lymphoma 6 protein | X-ray | 1.25 | 2021-08-18 | — | 52.06 | 0.93 | — | — | — | 0.04 | ok |
| 7RV9_A | P41182 | Isoform 2 of B-cell lymphoma 6 protein | X-ray | 1.50 | 2021-08-18 | — | 52.06 | 0.93 | — | — | — | 0.04 | ok |
| 7YEG_E | Q9BYF1 | Angiotensin-converting enzyme 2 | EM | 3.73 | 2022-07-05 | — | 90.69 | 0.97 | — | — | — | 0.03 | ok |
| 7T1K_A | P07332 | Tyrosine-protein kinase Fes/Fps | X-ray | 1.25 | 2021-12-02 | — | 89.38 | 0.96 | — | — | — | 0.03 | ok |
| 7UUU_A | Q58F21 | Bromodomain testis-specific protein | X-ray | 1.52 | 2022-04-29 | — | 62.44 | 0.95 | — | — | — | 0.03 | ok |
| 7WSL_D | Q15116 | Programmed cell death protein 1 | X-ray | 1.53 | 2022-01-30 | — | 74.12 | 0.96 | — | — | — | 0.03 | ok |
| 7MU5_A | Q9H773 | dCTP pyrophosphatase 1 | X-ray | 2.20 | 2021-05-14 | — | 83.62 | 0.97 | — | — | — | 0.03 | ok |
| 7RUG_A | Q13530 | Serine incorporator 3 | EM | 4.70 | 2021-08-17 | — | 76.31 | 0.96 | — | — | — | 0.03 | ok |
| 7RWE_A | P24941 | Cyclin-dependent kinase 2 | X-ray | 1.59 | 2021-08-19 | — | 88.44 | 0.97 | — | — | — | 0.02 | ok |
| 7U4T_1 | P27449 | V-type proton ATPase 16 kDa proteolipid su | EM | 3.60 | 2022-03-01 | — | 88.50 | 0.97 | — | — | — | 0.02 | ok |
| 7W54_C | P0CG47 | Polyubiquitin-B | X-ray | 2.64 | 2021-11-29 | — | 93.44 | 0.98 | — | — | — | 0.02 | ok |
| 7LIU_A | O00571 | ATP-dependent RNA helicase DDX3X | X-ray | 3.00 | 2021-01-27 | — | 72.19 | 0.97 | — | — | — | 0.02 | ok |
| 7UYR_A | P29597 | Non-receptor tyrosine-protein kinase TYK2 | X-ray | 2.15 | 2022-05-07 | — | 81.75 | 0.97 | — | — | — | 0.02 | ok |
| 7UYT_A | P29597 | Non-receptor tyrosine-protein kinase TYK2 | X-ray | 2.14 | 2022-05-07 | — | 81.75 | 0.97 | — | — | — | 0.02 | ok |
| 7Z21_A | O75531 | Barrier-to-autointegration factor, N-termi | X-ray | 1.63 | 2022-02-25 | — | 96.75 | 0.98 | — | — | — | 0.02 | ok |
| 7UYS_A | P29597 | Non-receptor tyrosine-protein kinase TYK2 | X-ray | 2.15 | 2022-05-07 | — | 81.75 | 0.98 | — | — | — | 0.02 | ok |
| 7U4T_0 | Q99437 | V-type proton ATPase 21 kDa proteolipid su | EM | 3.60 | 2022-03-01 | — | 92.69 | 0.98 | — | — | — | 0.02 | ok |
| 7RUH_A | O60885 | Bromodomain-containing protein 4 | X-ray | 1.70 | 2021-08-17 | — | 55.31 | 0.96 | — | — | — | 0.02 | ok |
| 7UYV_A | P52333 | Tyrosine-protein kinase JAK3 | X-ray | 2.15 | 2022-05-07 | — | 85.69 | 0.98 | — | — | — | 0.02 | ok |
| 7YDI_A | Q9BYF1 | Processed angiotensin-converting enzyme 2 | EM | 3.98 | 2022-07-04 | — | 90.69 | 0.98 | — | — | — | 0.02 | ok |
| 7UYU_A | P29597 | Non-receptor tyrosine-protein kinase TYK2 | X-ray | 2.05 | 2022-05-07 | — | 81.75 | 0.98 | — | — | — | 0.02 | ok |
| 7U4T_A | P38606 | V-type proton ATPase catalytic subunit A | EM | 3.60 | 2022-03-01 | — | 90.81 | 0.98 | — | — | — | 0.02 | ok |
| 7UYW_A | O60674 | Tyrosine-protein kinase JAK2 | X-ray | 2.51 | 2022-05-07 | — | 86.88 | 0.98 | — | — | — | 0.02 | ok |
| 7R6T_C | Q9Y2C4 | Nuclease EXOG, mitochondrial | X-ray | 2.90 | 2021-06-23 | — | 88.00 | 0.98 | — | — | — | 0.02 | ok |
| 7Z21_E | P02545 | Lamin-A/C | X-ray | 1.63 | 2022-02-25 | — | 76.38 | 0.98 | — | — | — | 0.02 | ok |
| 8ABX_A | P14902 | Indoleamine 2,3-dioxygenase 1 | X-ray | 1.65 | 2022-07-05 | — | 93.06 | 0.98 | — | — | — | 0.02 | ok |
| 7UTY_A | O60885 | Bromodomain-containing protein 4 | X-ray | 1.55 | 2022-04-28 | — | 55.31 | 0.97 | — | — | — | 0.01 | ok |
| 8DPI_C | P62873 | Guanine nucleotide-binding protein G(I)/G( | EM | 3.40 | 2022-07-15 | — | 97.06 | 0.99 | — | — | — | 0.01 | ok |
| 8DPG_C | P62873 | Guanine nucleotide-binding protein G(I)/G( | EM | 3.60 | 2022-07-15 | — | 97.06 | 0.99 | — | — | — | 0.01 | ok |
| 8DPF_C | P62873 | Guanine nucleotide-binding protein G(I)/G( | EM | 2.84 | 2022-07-15 | — | 97.06 | 0.99 | — | — | — | 0.01 | ok |
| 8DPH_C | P62873 | Guanine nucleotide-binding protein G(I)/G( | EM | 3.20 | 2022-07-15 | — | 97.06 | 0.99 | — | — | — | 0.01 | ok |
| 7RUI_A | O60885 | Bromodomain-containing protein 4 | X-ray | 1.35 | 2021-08-17 | — | 55.31 | 0.98 | — | — | — | 0.01 | ok |
| 7R6V_D | Q9Y2C4 | Nuclease EXOG, mitochondrial | X-ray | 2.16 | 2021-06-23 | — | 88.00 | 0.99 | — | — | — | 0.01 | ok |
| 7PG5_A | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-ki | X-ray | 2.20 | 2021-08-13 | — | 92.38 | 0.99 | — | — | — | 0.01 | ok |
| 7OIH_A | P05164 | Myeloperoxidase | X-ray | 2.60 | 2021-05-11 | — | 89.00 | 0.99 | — | — | — | 0.01 | ok |
| 7X9Y_B | P62873 | Guanine nucleotide-binding protein G(I)/G( | EM | 3.10 | 2022-03-16 | — | 97.06 | 0.99 | — | — | — | 0.01 | ok |
| 7PG6_A | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-ki | X-ray | 2.50 | 2021-08-13 | — | 92.38 | 0.99 | — | — | — | 0.01 | ok |
| 7YP7_B | P62873 | Guanine nucleotide-binding protein G(I)/G( | EM | 3.10 | 2022-08-02 | — | 97.06 | 0.99 | — | — | — | 0.01 | ok |
| 7V5U_A | P05413 | Fatty acid-binding protein, heart | X-ray | 0.92 | 2021-08-18 | — | 96.19 | 0.99 | — | — | — | 0.01 | ok |
| 7XZ6_B | P62873 | Guanine nucleotide-binding protein G(I)/G( | EM | 2.80 | 2022-06-02 | — | 97.06 | 0.99 | — | — | — | 0.01 | ok |
| 7THC_A | P30405 | Peptidyl-prolyl cis-trans isomerase F, mit | X-ray | 1.57 | 2022-01-10 | — | 88.31 | 0.99 | — | — | — | 0.01 | ok |
| 7THF_A | P30405 | Peptidyl-prolyl cis-trans isomerase F, mit | X-ray | 1.10 | 2022-01-10 | — | 88.31 | 0.99 | — | — | — | 0.01 | ok |
| 7THD_A | P30405 | Peptidyl-prolyl cis-trans isomerase F, mit | X-ray | 1.16 | 2022-01-10 | — | 88.31 | 0.99 | — | — | — | 0.01 | ok |
| 7RRD_A | P14902 | Indoleamine 2,3-dioxygenase 1 | X-ray | 2.76 | 2021-08-09 | — | 93.06 | 0.99 | — | — | — | 0.01 | ok |
| 7TH7_A | P30405 | Peptidyl-prolyl cis-trans isomerase F, mit | X-ray | 1.30 | 2022-01-10 | — | 88.31 | 0.99 | — | — | — | 0.01 | ok |
| 7TH1_X | P30405 | Peptidyl-prolyl cis-trans isomerase F, mit | X-ray | 1.52 | 2022-01-10 | — | 88.31 | 0.99 | — | — | — | 0.01 | ok |
| 7RRE_A | P00918 | Carbonic anhydrase 2 | X-ray | 1.44 | 2021-08-09 | — | 97.38 | 0.99 | — | — | — | 0.01 | ok |
| 7LU7_AAA | P48775 | Tryptophan 2,3-dioxygenase | X-ray | 2.30 | 2021-02-21 | — | 90.06 | 0.99 | — | — | — | 0.01 | ok |
| 7XW5_B | P62873 | Guanine nucleotide-binding protein G(I)/G( | EM | 2.96 | 2022-05-26 | — | 97.06 | 0.99 | — | — | — | 0.01 | ok |
| 7XA3_B | P62873 | Guanine nucleotide-binding protein G(I)/G( | EM | 2.90 | 2022-03-17 | — | 97.06 | 0.99 | — | — | — | 0.01 | ok |
| 7TGS_X | P30405 | Peptidyl-prolyl cis-trans isomerase F, mit | X-ray | 1.75 | 2022-01-09 | — | 88.31 | 0.99 | — | — | — | 0.01 | ok |
| 7TH6_A | P30405 | Peptidyl-prolyl cis-trans isomerase F, mit | X-ray | 0.97 | 2022-01-10 | — | 88.31 | 0.99 | — | — | — | 0.01 | ok |
| 7XZ5_B | P62873 | Guanine nucleotide-binding protein G(I)/G( | EM | 3.10 | 2022-06-02 | — | 97.06 | 1.00 | — | — | — | 0.00 | ok |
| 7TGT_X | P30405 | Peptidyl-prolyl cis-trans isomerase F, mit | X-ray | 1.06 | 2022-01-09 | — | 88.31 | 0.99 | — | — | — | 0.00 | ok |
| 7TGV_X | P30405 | Peptidyl-prolyl cis-trans isomerase F, mit | X-ray | 1.46 | 2022-01-09 | — | 88.31 | 1.00 | — | — | — | 0.00 | ok |
| 7TGU_X | P30405 | Peptidyl-prolyl cis-trans isomerase F, mit | X-ray | 1.21 | 2022-01-09 | — | 88.31 | 1.00 | — | — | — | 0.00 | ok |
| 7RRF_A | P00918 | Carbonic anhydrase 2 | X-ray | 1.45 | 2021-08-09 | — | 97.38 | 1.00 | — | — | — | 0.00 | ok |
Click a column header to sort. FRAUD = confidence-weighted error; a structure is flagged confidently wrong when mean pLDDT > 70 yet TM-score < 0.5.