Release week 2021-08-04
⭐ This week's notable releases
5 novel sequences, 2 confidently wrong. Highlight: Securin.
| PDB | Protein | Flags | Why it matters |
|---|---|---|---|
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Securin | novel · 100% confidently wrong | Genuinely unseen sequence (0% identity to anything AlphaFold trained on) — and AlphaFold got the fold wrong despite high confidence. |
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Apolipoprotein L1 | novel · 100% | Genuinely unseen sequence (0% identity to anything AlphaFold trained on). |
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Apolipoprotein L1 | novel · 100% | Genuinely unseen sequence (0% identity to anything AlphaFold trained on). |
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Nuclear receptor coactivator 2 | novel · 100% | Genuinely unseen sequence (0% identity to anything AlphaFold trained on). |
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Ubiquitin-like modifier-activating enzyme 5 | novel · 100% | Genuinely unseen sequence (0% identity to anything AlphaFold trained on). |
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Bcl-2-binding component 3, isoforms 1/2 | confidently wrong | A close pre-cutoff homolog existed yet AlphaFold confidently missed the fold. |
Zoomed into the red "confidently wrong" box above (pLDDT ≥ 70, TM < 0.5) — the structures AlphaFold got confidently wrong.
The worst offenders ranked, one row per protein (AlphaFold has one model per sequence, so repeat depositions are collapsed — “×N” marks how many structures of that protein exist; the worst is shown). Each row joins what AlphaFold claimed (blue, pLDDT/100) to what the experiment showed (red, TM-score) — the longer the bar, the bigger the miss. Hover a dot to preview its Cα-deviation ribbon; click to open the full entry.
How to read this
Every point is one experimental protein structure. The horizontal axis is AlphaFold's own confidence in its prediction (mean pLDDT, 0–100). The vertical axis is how well that blind prediction actually matches the experiment (TM-score, 0–1; above 0.5 means the same fold, above 0.9 near-identical). Marker size grows with the FRAUD score (confidence-weighted error).
Cutoff: the shaded red box is the "confidently wrong" zone — AlphaFold was confident (mean pLDDT above 70) yet the fold is wrong (TM-score below 0.5). A predictor that had truly solved folding would leave that box empty.
Take-home: 2 of 132 structures (1.5%) are confidently wrong; median TM-score is 0.924.
Read moreShow less — how each metric is calculated
TM-score: how similar the two 3D shapes are overall, 0–1 (a random pair scores ~0.17, an identical fold ~1). Length-normalised so large and small proteins compare fairly. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) — dᵢ is the gap between the i-th aligned Cα atoms after best-fit superposition, and d₀ = 1.24(L−15)^⅓ − 1.8 sets the distance scale for length L. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264; computed with TM-align, doi:10.1093/nar/gki524.
pLDDT: AlphaFold's own confidence in each residue, 0–100 (higher = surer). It is the model predicting its own accuracy before ever seeing the experiment. We plot the per-structure mean. pLDDT = (1/N) Σᵢ pLDDTᵢ, where pLDDTᵢ is the network's confidence output for residue i.
FRAUD score: the headline number — how wrong the prediction was, weighted by how confident AlphaFold was, so a big error it was sure about counts most. FRAUD = (1/N) Σᵢ (pLDDTᵢ/100) · min(Δᵢ,15)/15, where Δᵢ is residue i's Cα distance from the experiment (Å) after superposition, capped at 15 Å. Runs 0 (perfect) to 1.
Novelty: how little AlphaFold had to go on — 100 minus the highest sequence identity between this protein and any structure released before the 2018-04-30 training cutoff. High = genuinely unseen (100% = nothing similar was ever in the training set). novelty = 100 − maxₚ identity(s, p) over pre-cutoff PDB chains p, with identity = 100 × (matching aligned residues)/(alignment length), from an MMseqs2 search.
Homology: the point colour. High novelty (above 70%) flags the sequence as novel (amber) — AlphaFold had no close template; otherwise a pre-cutoff homolog existed (blue) it could have learned the fold from. novel ⇔ novelty > 70%.
What the metrics mean
TM-score (0–1): overall fold match — above 0.5 is the same fold, above 0.9 near-identical. Cα-RMSD (Å): average backbone distance after best-fit superposition — lower is better (under 2 Å is excellent). lDDT (0–1): local accuracy measured without superposition — above 0.8 is good. Each bar counts how many structures fall in that range.
Take-home: median TM-score 0.924 — most predictions match the experimental fold well, with a long tail that do not.
Read moreShow less — how each metric is calculated
TM-score: overall shape match, 0–1 (above 0.5 = same fold, above 0.9 near-identical), length-normalised. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) with dᵢ the aligned-Cα gap after superposition and d₀ = 1.24(L−15)^⅓ − 1.8. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264.
Cα-RMSD: the average straight-line distance between matching backbone Cα atoms once the two structures are best-fit superposed (Å; lower is better, under ~2 Å excellent). RMSD = √( (1/N) Σᵢ |Pᵢ − (R·Qᵢ + t)|² ), with Pᵢ/Qᵢ the experimental/model Cα coordinates and R,t the rotation and translation from Kabsch superposition.
lDDT: local accuracy with no superposition — the fraction of short-range inter-residue distances the model reproduces, so it is not fooled by a single wrongly-placed domain. lDDT = (1/N) Σᵢ ¼ Σ_t 1[ |d_exp − d_model| < t ] over thresholds t ∈ {0.5, 1, 2, 4} Å and all residue pairs within 15 Å.
Trend over time
The blue line is the mean TM-score of the structures by their deposit month; the red bars count how many were confidently wrong. Binning by deposit date (rather than by when we processed them) gives an even timeline, tracking whether AlphaFold's accuracy on newly-deposited structures is holding steady, improving, or slipping as the PDB keeps growing. Months with fewer than 5 structures are omitted so each point is a meaningful average. A dashed trend line is drawn only if the change over time is statistically significant.
Read moreShow less — how each metric is calculated
Mean TM-score: the month's average shape-match score. TM̄ = (1/M) Σ TM over the M structures deposited that month.
Trend line: a monotonic-trend test over the monthly means — Mann-Kendall (Kendall's τ) for significance, with a robust Theil-Sen slope for the line. Rank-based, so it tolerates the skewed TM distribution and noisy low-count months. Shown only when p < 0.05; otherwise a note reports that no significant trend was found.
Confidently wrong: the count that were both confident and wrong. count( mean pLDDT > 70 AND TM < 0.5 ).
Matched structures
| PDB | UniProt | Protein | Method | Å | Deposited | Novelty % | pLDDT | TM | lDDT | GDT_TS | RMSD | FRAUD | Flag |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 7NJ1_B | O95997 | Securin | EM | 2.90 | 2021-02-14 | 100.00 novel | 79.90 | 0.24 | 0.79 | 3.12 | 25.83 | 0.74 | wrong |
| 7L6K_A | O14791 | Apolipoprotein L1 | NMR | — | 2020-12-23 | 100.00 novel | 72.41 | 0.68 | 0.54 | 8.33 | 17.26 | 0.56 | ok |
| 7LFB_X | O14791 | Apolipoprotein L1 | X-ray | 1.91 | 2021-01-16 | 100.00 novel | 70.78 | 0.52 | 0.68 | 6.88 | 12.27 | 0.53 | ok |
| 7LC1_B | Q9BPZ7 | Target of rapamycin complex 2 subunit MAPK | X-ray | 2.35 | 2021-01-09 | 0.00 | 75.06 | 0.60 | 0.82 | 13.88 | 10.95 | 0.45 | ok |
| 7R7T_A | P55072 | Transitional endoplasmic reticulum ATPase | EM | 4.50 | 2021-06-25 | 0.20 | 86.07 | 0.69 | 0.73 | 24.76 | 8.92 | 0.40 | ok |
| 7KI1_A | P63092 | Guanine nucleotide-binding protein G(s) su | EM | 2.50 | 2020-10-22 | — | 91.31 | 0.72 | — | — | — | 0.26 | ok |
| 7R7S_A | P55072 | Transitional endoplasmic reticulum ATPase | EM | 4.23 | 2021-06-25 | — | 82.56 | 0.70 | — | — | — | 0.24 | ok |
| 7CNF_A | P23193 | Transcription elongation factor A protein | NMR | — | 2020-07-31 | — | 80.06 | 0.71 | — | — | — | 0.23 | ok |
| 7APO_C | Q15596 | Nuclear receptor coactivator 2 | X-ray | 2.40 | 2020-10-19 | — | 47.59 | 0.53 | — | — | — | 0.22 | ok |
| 7L5W_A | P55072 | Transitional endoplasmic reticulum ATPase | EM | 3.34 | 2020-12-23 | — | 82.56 | 0.76 | — | — | — | 0.20 | ok |
| 7R7U_A | P55072 | Transitional endoplasmic reticulum ATPase | EM | 4.30 | 2021-06-25 | — | 82.56 | 0.76 | — | — | — | 0.20 | ok |
| 7L5X_A | P55072 | Transitional endoplasmic reticulum ATPase | EM | 6.10 | 2020-12-23 | — | 82.56 | 0.76 | — | — | — | 0.20 | ok |
| 7BK4_B | Q15596 | Nuclear receptor coactivator 2 | X-ray | 2.80 | 2021-01-15 | 100.00 novel | 62.69 | 0.33 | 0.62 | 38.75 | 4.47 | 0.18 | ok |
| 7EXD_A | P63096 | Guanine nucleotide-binding protein G(i) su | EM | 3.40 | 2021-05-27 | — | 93.75 | 0.81 | — | — | — | 0.18 | ok |
| 7KI0_R | P43220 | Glucagon-like peptide 1 receptor | EM | 2.50 | 2020-10-22 | — | 81.50 | 0.80 | — | — | — | 0.16 | ok |
| 7DVD_E | Q9BXH1 | Bcl-2-binding component 3, isoforms 1/2 | X-ray | 2.59 | 2021-01-13 | — | 95.80 | 0.25 | 0.64 | 56.67 | 2.71 | 0.16 | wrong |
| 7DPA_C | Q92556 | Engulfment and cell motility protein 1 | EM | 3.80 | 2020-12-18 | — | 88.88 | 0.82 | — | — | — | 0.16 | ok |
| 7DTY_R | P48546 | human glucose-dependent insulinotropic pol | EM | 2.98 | 2021-01-06 | — | 78.50 | 0.80 | — | — | — | 0.16 | ok |
| 7ONB_C | O75533 | Splicing factor 3B subunit 1 | EM | 3.10 | 2021-05-25 | — | 74.81 | 0.80 | — | — | — | 0.15 | ok |
| 7LFD_A | O14791 | Apolipoprotein L1 BH3 like peptide | X-ray | 2.16 | 2021-01-16 | — | 62.83 | 0.57 | 0.79 | 48.53 | 4.09 | 0.15 | ok |
| 7B0I_C | O75533 | Splicing factor 3B subunit 1 | X-ray | 3.00 | 2020-11-19 | — | 74.81 | 0.81 | — | — | — | 0.15 | ok |
| 7B9C_C | O75533 | Splicing factor 3B subunit 1 | X-ray | 2.40 | 2020-12-14 | — | 74.81 | 0.81 | — | — | — | 0.15 | ok |
| 7OMF_C | O75533 | Splicing factor 3B subunit 1 | X-ray | 3.00 | 2021-05-21 | — | 74.81 | 0.81 | — | — | — | 0.14 | ok |
| 6ZVE_P | Q9UQC2 | phosphorylated Gab2pT391 peptide | X-ray | 2.51 | 2020-07-24 | — | 46.56 | 0.26 | 0.60 | 42.50 | 5.04 | 0.14 | ok |
| 6ZVC_P | Q9UQC2 | phosphorylated Gab2pT391 peptide | X-ray | 2.51 | 2020-07-24 | — | 46.56 | 0.29 | 0.57 | 40.00 | 5.05 | 0.14 | ok |
| 6ZVB_P | Q9UQC2 | phosphorylated Gab2pT391 peptide | X-ray | 2.51 | 2020-07-24 | — | 46.56 | 0.32 | 0.60 | 37.50 | 5.01 | 0.14 | ok |
| 7DPA_A | Q9H7D0 | Dedicator of cytokinesis protein 5 | EM | 3.80 | 2020-12-18 | — | 78.94 | 0.82 | — | — | — | 0.14 | ok |
| 6ZVD_P | Q9UQC2 | phosphorylated Gab2pT391 peptide | X-ray | 2.50 | 2020-07-24 | — | 46.56 | 0.29 | 0.56 | 40.00 | 5.02 | 0.14 | ok |
| 7B92_C | O75533 | Splicing factor 3B subunit 1 | X-ray | 3.00 | 2020-12-14 | — | 74.81 | 0.81 | — | — | — | 0.14 | ok |
| 7OPI_C | O75533 | Splicing factor 3B subunit 1 | X-ray | 3.10 | 2021-05-31 | — | 74.81 | 0.81 | — | — | — | 0.14 | ok |
| 7B91_C | O75533 | Splicing factor 3B subunit 1 | X-ray | 3.00 | 2020-12-13 | — | 74.81 | 0.81 | — | — | — | 0.14 | ok |
| 7AOS_C | Q15788 | Nuclear receptor coactivator 1 | X-ray | 2.55 | 2020-10-15 | — | 46.72 | 0.71 | — | — | — | 0.14 | ok |
| 7LFA_A | O14791 | Apolipoprotein L1 | X-ray | 1.86 | 2021-01-15 | — | 51.91 | 0.74 | — | — | — | 0.13 | ok |
| 7KI1_R | P43220 | Glucagon-like peptide 1 receptor | EM | 2.50 | 2020-10-22 | — | 81.50 | 0.84 | — | — | — | 0.13 | ok |
| 7KI0_A | P63092 | Guanine nucleotide-binding protein G(s) su | EM | 2.50 | 2020-10-22 | — | 91.31 | 0.86 | — | — | — | 0.13 | ok |
| 6ZVA_A | P52179 | Myomesin-1 | X-ray | 2.68 | 2020-07-24 | — | 68.94 | 0.82 | — | — | — | 0.12 | ok |
| 7OVC_A | Q9Y3C8 | Ubiquitin-fold modifier-conjugating enzyme | NMR | — | 2021-06-14 | — | 93.44 | 0.87 | — | — | — | 0.12 | ok |
| 7DPA_B | P63000 | Ras-related C3 botulinum toxin substrate 1 | EM | 3.80 | 2020-12-18 | — | 93.81 | 0.87 | — | — | — | 0.12 | ok |
| 7DTY_P | P09681 | Gastric inhibitory polypeptide | EM | 2.98 | 2021-01-06 | — | 69.19 | 0.83 | — | — | — | 0.11 | ok |
| 7DH5_A | P63092 | Guanine nucleotide-binding protein G(s) su | EM | 3.16 | 2020-11-12 | — | 91.31 | 0.88 | — | — | — | 0.11 | ok |
| 7OMF_D | Q7RTV0 | PHD finger-like domain-containing protein | X-ray | 3.00 | 2021-05-21 | — | 89.88 | 0.88 | — | — | — | 0.11 | ok |
| 7LF7_K | O14791 | Apolipoprotein L1 | X-ray | 2.03 | 2021-01-15 | — | 51.91 | 0.79 | — | — | — | 0.11 | ok |
| 7B0I_D | Q7RTV0 | PHD finger-like domain-containing protein | X-ray | 3.00 | 2020-11-19 | — | 89.88 | 0.88 | — | — | — | 0.10 | ok |
| 7B9C_B | Q9BWJ5 | Splicing factor 3B subunit 5 | X-ray | 2.40 | 2020-12-14 | — | 91.62 | 0.89 | — | — | — | 0.10 | ok |
| 7OPI_D | Q7RTV0 | PHD finger-like domain-containing protein | X-ray | 3.10 | 2021-05-31 | — | 89.88 | 0.89 | — | — | — | 0.10 | ok |
| 7B92_D | Q7RTV0 | PHD finger-like domain-containing protein | X-ray | 3.00 | 2020-12-14 | — | 89.88 | 0.89 | — | — | — | 0.10 | ok |
| 6W8P_A | Q9BSA9 | Endosomal/lysosomal potassium channel TMEM | EM | 3.60 | 2020-03-21 | — | 81.75 | 0.88 | — | — | — | 0.10 | ok |
| 6W8O_A | Q9BSA9 | Endosomal/lysosomal potassium channel TMEM | EM | 3.40 | 2020-03-20 | — | 81.75 | 0.88 | — | — | — | 0.10 | ok |
| 7B9C_D | Q7RTV0 | PHD finger-like domain-containing protein | X-ray | 2.40 | 2020-12-14 | — | 89.88 | 0.89 | — | — | — | 0.10 | ok |
| 6W8N_A | Q9BSA9 | Endosomal/lysosomal potassium channel TMEM | EM | 3.20 | 2020-03-20 | — | 81.75 | 0.88 | — | — | — | 0.10 | ok |
| 7ONB_N | Q12874 | Splicing factor 3A subunit 3 | EM | 3.10 | 2021-05-25 | — | 86.25 | 0.89 | — | — | — | 0.10 | ok |
| 7B91_D | Q7RTV0 | PHD finger-like domain-containing protein | X-ray | 3.00 | 2020-12-13 | — | 89.88 | 0.90 | — | — | — | 0.09 | ok |
| 7NJ0_B | P06493 | Cyclin-dependent kinase 1 | EM | 3.60 | 2021-02-14 | — | 89.31 | 0.91 | — | — | — | 0.08 | ok |
| 7ONB_I | Q13435 | Splicing factor 3B subunit 2 | EM | 3.10 | 2021-05-25 | — | 65.69 | 0.88 | — | — | — | 0.08 | ok |
| 7OVC_B | Q9GZZ9 | Ubiquitin-like modifier-activating enzyme | NMR | — | 2021-06-14 | 100.00 novel | 56.88 | 0.43 | 0.77 | 61.54 | 2.67 | 0.08 | ok |
| 7M2G_A | P60568 | Interleukin-2 | X-ray | 1.79 | 2021-03-16 | — | 84.12 | 0.91 | — | — | — | 0.08 | ok |
| 7NJ1_A | Q14674 | Separin | EM | 2.90 | 2021-02-14 | — | 75.31 | 0.90 | — | — | — | 0.08 | ok |
| 7EXD_G | P59768 | Guanine nucleotide-binding protein G(I)/G( | EM | 3.40 | 2021-05-27 | — | 89.56 | 0.92 | — | — | — | 0.07 | ok |
| 7B0I_B | Q9BWJ5 | Splicing factor 3B subunit 5 | X-ray | 3.00 | 2020-11-19 | — | 91.62 | 0.92 | — | — | — | 0.07 | ok |
| 7B7S_A | P24941 | Cyclin-dependent kinase 2 | X-ray | 2.54 | 2020-12-11 | — | 88.44 | 0.92 | — | — | — | 0.07 | ok |
| 7B91_B | Q9BWJ5 | Splicing factor 3B subunit 5 | X-ray | 3.00 | 2020-12-13 | — | 91.62 | 0.92 | — | — | — | 0.07 | ok |
| 7ONB_B | Q9BWJ5 | Splicing factor 3B subunit 5 | EM | 3.10 | 2021-05-25 | — | 91.62 | 0.92 | — | — | — | 0.07 | ok |
| 7B92_B | Q9BWJ5 | Splicing factor 3B subunit 5 | X-ray | 3.00 | 2020-12-14 | — | 91.62 | 0.92 | — | — | — | 0.07 | ok |
| 7OMF_B | Q9BWJ5 | Splicing factor 3B subunit 5 | X-ray | 3.00 | 2021-05-21 | — | 91.62 | 0.92 | — | — | — | 0.07 | ok |
| 7OPI_B | Q9BWJ5 | Splicing factor 3B subunit 5 | X-ray | 3.10 | 2021-05-31 | — | 91.62 | 0.93 | — | — | — | 0.07 | ok |
| 7ONB_K | Q15427 | Splicing factor 3B subunit 4 | EM | 3.10 | 2021-05-25 | — | 73.19 | 0.91 | — | — | — | 0.07 | ok |
| 6QFA_A | P28472 | Gamma-aminobutyric acid receptor subunit b | EM | 2.49 | 2019-01-09 | 0.30 | 93.48 | 0.98 | 0.95 | 89.26 | 2.04 | 0.07 | ok |
| 7OOX_A | P11309 | Serine/threonine-protein kinase pim-1 | X-ray | 1.97 | 2021-05-28 | — | 89.44 | 0.93 | — | — | — | 0.06 | ok |
| 7EU7_B | Q12879 | Glutamate receptor ionotropic, NMDA 2A | EM | 3.50 | 2021-05-16 | — | 60.84 | 0.90 | — | — | — | 0.06 | ok |
| 7ONB_M | Q15428 | Splicing factor 3A subunit 2 | EM | 3.10 | 2021-05-25 | — | 64.06 | 0.92 | — | — | — | 0.05 | ok |
| 7NJ0_D | P61024 | Cyclin-dependent kinases regulatory subuni | EM | 3.60 | 2021-02-14 | — | 92.06 | 0.95 | — | — | — | 0.05 | ok |
| 7KI1_G | P59768 | Guanine nucleotide-binding protein G(I)/G( | EM | 2.50 | 2020-10-22 | — | 89.56 | 0.94 | — | — | — | 0.05 | ok |
| 7JU8_A | P45452 | Collagenase 3 | X-ray | 2.00 | 2020-08-19 | — | 88.62 | 0.95 | — | — | — | 0.04 | ok |
| 7AH8_A | P25208 | Nuclear transcription factor Y subunit bet | X-ray | 2.70 | 2020-09-24 | — | 69.56 | 0.94 | — | — | — | 0.04 | ok |
| 7KI0_G | P59768 | Guanine nucleotide-binding protein G(I)/G( | EM | 2.50 | 2020-10-22 | — | 89.56 | 0.96 | — | — | — | 0.04 | ok |
| 7EU7_A | Q05586 | Glutamate receptor ionotropic, NMDA 1 | EM | 3.50 | 2021-05-16 | — | 82.88 | 0.96 | — | — | — | 0.03 | ok |
| 7LF8_A | Q9BQE5 | Apolipoprotein L2 | X-ray | 2.15 | 2021-01-15 | — | 52.50 | 0.94 | — | — | — | 0.03 | ok |
| 6ZVE_A | P31947 | 14-3-3 protein sigma | X-ray | 2.51 | 2020-07-24 | — | 92.88 | 0.97 | — | — | — | 0.03 | ok |
| 6ZVB_A | P31947 | 14-3-3 protein sigma | X-ray | 2.51 | 2020-07-24 | — | 92.88 | 0.97 | — | — | — | 0.03 | ok |
| 6ZVD_A | P31947 | 14-3-3 protein sigma | X-ray | 2.50 | 2020-07-24 | — | 92.88 | 0.97 | — | — | — | 0.03 | ok |
| 6ZVC_A | P31947 | 14-3-3 protein sigma | X-ray | 2.51 | 2020-07-24 | — | 92.88 | 0.97 | — | — | — | 0.03 | ok |
| 7EAS_A | Q15119 | [Pyruvate dehydrogenase (acetyl-transferri | X-ray | 1.97 | 2021-03-08 | — | 90.75 | 0.97 | — | — | — | 0.03 | ok |
| 7EBH_A | Q15119 | [Pyruvate dehydrogenase (acetyl-transferri | X-ray | 1.96 | 2021-03-09 | — | 90.75 | 0.97 | — | — | — | 0.03 | ok |
| 7EA0_A | Q15119 | [Pyruvate dehydrogenase (acetyl-transferri | X-ray | 2.34 | 2021-03-05 | — | 90.75 | 0.97 | — | — | — | 0.02 | ok |
| 7ONB_A | Q15393 | Splicing factor 3B subunit 3 | EM | 3.10 | 2021-05-25 | — | 92.25 | 0.98 | — | — | — | 0.02 | ok |
| 7ONB_D | Q7RTV0 | PHD finger-like domain-containing protein | EM | 3.10 | 2021-05-25 | — | 89.88 | 0.98 | — | — | — | 0.02 | ok |
| 7A7H_A | P37231 | Peroxisome proliferator-activated receptor | X-ray | 2.40 | 2020-08-28 | — | 76.12 | 0.98 | — | — | — | 0.02 | ok |
| 7AH8_B | Q13952 | Isoform 6 of Nuclear transcription factor | X-ray | 2.70 | 2020-09-24 | — | 49.47 | 0.97 | — | — | — | 0.02 | ok |
| 7JXV_B | P0CG48 | Ubiquitin | X-ray | 2.35 | 2020-08-28 | — | 88.62 | 0.98 | — | — | — | 0.02 | ok |
| 7K7O_A | P29597 | Non-receptor tyrosine-protein kinase TYK2 | X-ray | 2.82 | 2020-09-23 | — | 81.75 | 0.98 | — | — | — | 0.02 | ok |
| 7BK4_A | P19793 | Retinoic acid receptor RXR-alpha | X-ray | 2.80 | 2021-01-15 | — | 75.38 | 0.98 | — | — | — | 0.02 | ok |
| 7AOS_B | P10276 | Retinoic acid receptor alpha | X-ray | 2.55 | 2020-10-15 | — | 78.12 | 0.98 | — | — | — | 0.02 | ok |
| 7JVX_A | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3 | X-ray | 3.20 | 2020-08-24 | — | 83.00 | 0.98 | — | — | — | 0.02 | ok |
| 7DF8_A | Q9UHC9 | NPC1-like intracellular cholesterol transp | EM | 3.03 | 2020-11-06 | — | 84.19 | 0.98 | — | — | — | 0.01 | ok |
| 7AT9_A | P19784 | Casein kinase II subunit alpha' | X-ray | 1.05 | 2020-10-29 | — | 94.12 | 0.98 | — | — | — | 0.01 | ok |
| 7AT5_A | P68400 | Casein kinase II subunit alpha | X-ray | 1.77 | 2020-10-29 | — | 88.94 | 0.99 | — | — | — | 0.01 | ok |
| 7KPR_A | Q9ULR3 | Protein phosphatase 1H | X-ray | 3.09 | 2020-11-12 | — | 83.94 | 0.99 | — | — | — | 0.01 | ok |
| 7K7Q_A | P29597 | Non-receptor tyrosine-protein kinase TYK2 | X-ray | 2.27 | 2020-09-23 | — | 81.75 | 0.98 | — | — | — | 0.01 | ok |
| 7ATV_A | P19784 | Casein kinase II subunit alpha' | X-ray | 0.98 | 2020-10-31 | — | 94.12 | 0.99 | — | — | — | 0.01 | ok |
| 7L4I_A | Q9ULR3 | Protein phosphatase 1H | X-ray | 2.58 | 2020-12-19 | — | 83.94 | 0.99 | — | — | — | 0.01 | ok |
| 7L4J_A | Q9ULR3 | Protein phosphatase 1H | X-ray | 2.45 | 2020-12-19 | — | 83.94 | 0.99 | — | — | — | 0.01 | ok |
| 7DVD_A | P04637 | Cellular tumor antigen p53 | X-ray | 2.59 | 2021-01-13 | — | 75.06 | 0.99 | — | — | — | 0.01 | ok |
| 7EBG_A | Q16654 | [Pyruvate dehydrogenase (acetyl-transferri | X-ray | 1.95 | 2021-03-09 | — | 89.06 | 0.99 | — | — | — | 0.01 | ok |
| 7N0Z_A | Q9ULR3 | Protein phosphatase 1H | X-ray | 2.19 | 2021-05-26 | — | 83.94 | 0.99 | — | — | — | 0.01 | ok |
| 7B2V_A | Q6P988 | Palmitoleoyl-protein carboxylesterase NOTU | X-ray | 1.24 | 2020-11-28 | — | 83.94 | 0.99 | — | — | — | 0.01 | ok |
| 7B2Y_A | Q6P988 | Palmitoleoyl-protein carboxylesterase NOTU | X-ray | 1.23 | 2020-11-28 | — | 83.94 | 0.99 | — | — | — | 0.01 | ok |
| 7EAT_A | Q16654 | [Pyruvate dehydrogenase (acetyl-transferri | X-ray | 2.10 | 2021-03-08 | — | 89.06 | 0.99 | — | — | — | 0.01 | ok |
| 7B3F_A | Q6P988 | Palmitoleoyl-protein carboxylesterase NOTU | X-ray | 1.39 | 2020-11-30 | — | 83.94 | 0.99 | — | — | — | 0.01 | ok |
| 7LPG_B | P27695 | DNA-(apurinic or apyrimidinic site) lyase | X-ray | 2.08 | 2021-02-11 | — | 90.44 | 0.99 | — | — | — | 0.01 | ok |
| 7NJ0_C | P14635 | G2/mitotic-specific cyclin-B1,G2/mitotic-s | EM | 3.60 | 2021-02-14 | — | 76.56 | 0.99 | — | — | — | 0.01 | ok |
| 7OMF_A | Q15393 | Splicing factor 3B subunit 3 | X-ray | 3.00 | 2021-05-21 | — | 92.25 | 0.99 | — | — | — | 0.01 | ok |
| 7B9C_A | Q15393 | Splicing factor 3B subunit 3 | X-ray | 2.40 | 2020-12-14 | — | 92.25 | 0.99 | — | — | — | 0.01 | ok |
| 7B92_A | Q15393 | Splicing factor 3B subunit 3 | X-ray | 3.00 | 2020-12-14 | — | 92.25 | 0.99 | — | — | — | 0.01 | ok |
| 7B0I_A | Q15393 | Splicing factor 3B subunit 3,Splicing fact | X-ray | 3.00 | 2020-11-19 | — | 92.25 | 0.99 | — | — | — | 0.01 | ok |
| 7APO_A | P10276 | Retinoic acid receptor alpha | X-ray | 2.40 | 2020-10-19 | — | 78.12 | 0.99 | — | — | — | 0.01 | ok |
| 7EBB_A | Q16654 | [Pyruvate dehydrogenase (acetyl-transferri | X-ray | 1.90 | 2021-03-09 | — | 89.06 | 0.99 | — | — | — | 0.01 | ok |
| 7B91_A | Q15393 | Splicing factor 3B subunit 3 | X-ray | 3.00 | 2020-12-13 | — | 92.25 | 0.99 | — | — | — | 0.01 | ok |
| 7EXD_B | P62873 | Guanine nucleotide-binding protein G(I)/G( | EM | 3.40 | 2021-05-27 | — | 97.06 | 0.99 | — | — | — | 0.01 | ok |
| 7LC1_A | P01116 | Isoform 2B of GTPase KRas | X-ray | 2.35 | 2021-01-09 | — | 91.50 | 0.99 | — | — | — | 0.01 | ok |
| 7ABS_A | Q96SD1 | Protein artemis | X-ray | 1.97 | 2020-09-08 | — | 69.44 | 0.99 | — | — | — | 0.01 | ok |
| 7B37_A | Q6P988 | Palmitoleoyl-protein carboxylesterase NOTU | X-ray | 1.34 | 2020-11-28 | — | 83.94 | 0.99 | — | — | — | 0.01 | ok |
| 7ARG_A | Q6P988 | Palmitoleoyl-protein carboxylesterase NOTU | X-ray | 1.24 | 2020-10-24 | — | 83.94 | 0.99 | — | — | — | 0.01 | ok |
| 7OOW_A | P11309 | Serine/threonine-protein kinase pim-1 | X-ray | 1.95 | 2021-05-28 | — | 89.44 | 0.99 | — | — | — | 0.00 | ok |
| 7B2Z_A | Q6P988 | Palmitoleoyl-protein carboxylesterase NOTU | X-ray | 1.24 | 2020-11-28 | — | 83.94 | 0.99 | — | — | — | 0.00 | ok |
| 7KI1_B | P62873 | Guanine nucleotide-binding protein G(I)/G( | EM | 2.50 | 2020-10-22 | — | 97.06 | 1.00 | — | — | — | 0.00 | ok |
| 7LPJ_B | P27695 | DNA-(apurinic or apyrimidinic site) lyase | X-ray | 2.56 | 2021-02-11 | — | 90.44 | 1.00 | — | — | — | 0.00 | ok |
| 7KI0_B | P62873 | Guanine nucleotide-binding protein G(I)/G( | EM | 2.50 | 2020-10-22 | — | 97.06 | 1.00 | — | — | — | 0.00 | ok |
| 7OOV_A | P11309 | Serine/threonine-protein kinase pim-1 | X-ray | 1.96 | 2021-05-28 | — | 89.44 | 1.00 | — | — | — | 0.00 | ok |
| 7LPI_B | P27695 | DNA-(apurinic or apyrimidinic site) lyase | X-ray | 2.05 | 2021-02-11 | — | 90.44 | 1.00 | — | — | — | 0.00 | ok |
| 7LPH_B | P27695 | DNA-(apurinic or apyrimidinic site) lyase | X-ray | 1.99 | 2021-02-11 | — | 90.44 | 1.00 | — | — | — | 0.00 | ok |
| 7B7S_B | P20248 | Cyclin-A2 | X-ray | 2.54 | 2020-12-11 | — | 73.06 | 1.00 | — | — | — | 0.00 | ok |
| 7A7G_A | P34913 | Bifunctional epoxide hydrolase 2 | X-ray | 2.40 | 2020-08-28 | — | 93.31 | 1.00 | — | — | — | 0.00 | ok |
Click a column header to sort. FRAUD = confidence-weighted error; a structure is flagged confidently wrong when mean pLDDT > 70 yet TM-score < 0.5.