Release week 2021-03-31

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124

structures analysed (21 full · 16.9%)

54.0%

confidently wrong

32.4%

novel sequences

10.8%

novel & wrong

0.947

median TM-score

⭐ This week's notable releases

3 novel sequences, 5 confidently wrong. Highlight: Sodium channel modifier 1.

PDB	Protein	Flags	Why it matters
7DVQ_v ↗	Sodium channel modifier 1	novel · 100% confidently wrong	Genuinely unseen sequence (0% identity to anything AlphaFold trained on) — and AlphaFold got the fold wrong despite high confidence.
7DVQ_0 ↗	Cysteine-rich PDZ-binding protein	novel · 100%	Genuinely unseen sequence (0% identity to anything AlphaFold trained on).
7DVQ_y ↗	G-patch domain and KOW motifs-containing protein	novel · 100%	Genuinely unseen sequence (0% identity to anything AlphaFold trained on).
7DVQ_9 ↗	RING-type E3 ubiquitin-protein ligase PPIL2	confidently wrong	A close pre-cutoff homolog existed (100% identity to 1ZKC_1) yet AlphaFold confidently missed the fold.
7DVQ_M ↗	RING finger protein 113A	confidently wrong	A close pre-cutoff homolog existed (43% identity to 5GM6_25) yet AlphaFold confidently missed the fold.
7NE0_C ↗	Repulsive Guidance Molecule B	confidently wrong	A close pre-cutoff homolog existed (97% identity to 4BQ6_2) yet AlphaFold confidently missed the fold.

see all 124 structures ↓

Zoomed into the red "confidently wrong" box above (pLDDT ≥ 70, TM < 0.5) — the structures AlphaFold got confidently wrong.

The worst offenders ranked, one row per protein (AlphaFold has one model per sequence, so repeat depositions are collapsed — “×N” marks how many structures of that protein exist; the worst is shown). Each row joins what AlphaFold claimed (blue, pLDDT/100) to what the experiment showed (red, TM-score) — the longer the bar, the bigger the miss. Hover a dot to preview its Cα-deviation ribbon; click to open the full entry.

How to read this

Every point is one experimental protein structure. The horizontal axis is AlphaFold's own confidence in its prediction (mean pLDDT, 0–100). The vertical axis is how well that blind prediction actually matches the experiment (TM-score, 0–1; above 0.5 means the same fold, above 0.9 near-identical). Marker size grows with the FRAUD score (confidence-weighted error).

Cutoff: the shaded red box is the "confidently wrong" zone — AlphaFold was confident (mean pLDDT above 70) yet the fold is wrong (TM-score below 0.5). A predictor that had truly solved folding would leave that box empty.

Take-home: 5 of 124 structures (4.0%) are confidently wrong; median TM-score is 0.947.

Read moreShow less — how each metric is calculated

TM-score: how similar the two 3D shapes are overall, 0–1 (a random pair scores ~0.17, an identical fold ~1). Length-normalised so large and small proteins compare fairly. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) — dᵢ is the gap between the i-th aligned Cα atoms after best-fit superposition, and d₀ = 1.24(L−15)^⅓ − 1.8 sets the distance scale for length L. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264; computed with TM-align, doi:10.1093/nar/gki524.

pLDDT: AlphaFold's own confidence in each residue, 0–100 (higher = surer). It is the model predicting its own accuracy before ever seeing the experiment. We plot the per-structure mean. pLDDT = (1/N) Σᵢ pLDDTᵢ, where pLDDTᵢ is the network's confidence output for residue i.

FRAUD score: the headline number — how wrong the prediction was, weighted by how confident AlphaFold was, so a big error it was sure about counts most. FRAUD = (1/N) Σᵢ (pLDDTᵢ/100) · min(Δᵢ,15)/15, where Δᵢ is residue i's Cα distance from the experiment (Å) after superposition, capped at 15 Å. Runs 0 (perfect) to 1.

Novelty: how little AlphaFold had to go on — 100 minus the highest sequence identity between this protein and any structure released before the 2018-04-30 training cutoff. High = genuinely unseen (100% = nothing similar was ever in the training set). novelty = 100 − maxₚ identity(s, p) over pre-cutoff PDB chains p, with identity = 100 × (matching aligned residues)/(alignment length), from an MMseqs2 search.

Homology: the point colour. High novelty (above 70%) flags the sequence as novel (amber) — AlphaFold had no close template; otherwise a pre-cutoff homolog existed (blue) it could have learned the fold from. novel ⇔ novelty > 70%.

What the metrics mean

TM-score (0–1): overall fold match — above 0.5 is the same fold, above 0.9 near-identical. Cα-RMSD (Å): average backbone distance after best-fit superposition — lower is better (under 2 Å is excellent). lDDT (0–1): local accuracy measured without superposition — above 0.8 is good. Each bar counts how many structures fall in that range.

Take-home: median TM-score 0.947 — most predictions match the experimental fold well, with a long tail that do not.

Read moreShow less — how each metric is calculated

TM-score: overall shape match, 0–1 (above 0.5 = same fold, above 0.9 near-identical), length-normalised. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) with dᵢ the aligned-Cα gap after superposition and d₀ = 1.24(L−15)^⅓ − 1.8. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264.

Cα-RMSD: the average straight-line distance between matching backbone Cα atoms once the two structures are best-fit superposed (Å; lower is better, under ~2 Å excellent). RMSD = √( (1/N) Σᵢ |Pᵢ − (R·Qᵢ + t)|² ), with Pᵢ/Qᵢ the experimental/model Cα coordinates and R,t the rotation and translation from Kabsch superposition.

lDDT: local accuracy with no superposition — the fraction of short-range inter-residue distances the model reproduces, so it is not fooled by a single wrongly-placed domain. lDDT = (1/N) Σᵢ ¼ Σ_t 1[ |d_exp − d_model| < t ] over thresholds t ∈ {0.5, 1, 2, 4} Å and all residue pairs within 15 Å.

Trend over time

The blue line is the mean TM-score of the structures by their deposit month; the red bars count how many were confidently wrong. Binning by deposit date (rather than by when we processed them) gives an even timeline, tracking whether AlphaFold's accuracy on newly-deposited structures is holding steady, improving, or slipping as the PDB keeps growing. Months with fewer than 5 structures are omitted so each point is a meaningful average. A dashed trend line is drawn only if the change over time is statistically significant.

Read moreShow less — how each metric is calculated

Mean TM-score: the month's average shape-match score. TM̄ = (1/M) Σ TM over the M structures deposited that month.

Trend line: a monotonic-trend test over the monthly means — Mann-Kendall (Kendall's τ) for significance, with a robust Theil-Sen slope for the line. Rank-based, so it tolerates the skewed TM distribution and noisy low-count months. Shown only when p < 0.05; otherwise a note reports that no significant trend was found.

Confidently wrong: the count that were both confident and wrong. count( mean pLDDT > 70 AND TM < 0.5 ).

Matched structures

PDB	UniProt	Protein	Method	Å	Deposited	Novelty %	pLDDT	TM	lDDT	GDT_TS	RMSD	FRAUD	Flag
7M4R_A	Q8N3R9	MAGUK p55 subfamily member 5	EM	3.65	2021-03-22	0.30	91.73	0.59	0.79	2.85	20.78	0.81	ok
7DVQ_v	Q9BWG6	Sodium channel modifier 1	EM	2.89	2021-01-14	100.00 novel	83.52	0.46	0.85	1.89	25.05	0.78	wrong
7K02_A	Q16611	Bcl-2 homologous antagonist/killer	X-ray	3.40	2020-09-02	0.00	86.57	0.53	0.81	5.71	19.34	0.71	ok
7DVQ_9	Q13356	RING-type E3 ubiquitin-protein ligase PPIL	EM	2.89	2021-01-14	0.00	86.91	0.49	0.91	3.36	15.05	0.71	wrong
7DVQ_V	Q9HCG8	Pre-mRNA-splicing factor CWC22 homolog	EM	2.89	2021-01-14	0.00	89.74	0.61	0.96	8.33	11.17	0.59	ok
7DVQ_J	Q9BZJ0	Crooked neck-like protein 1	EM	2.89	2021-01-14	0.00	88.30	0.67	0.56	14.89	12.64	0.54	ok
7DVQ_M	O15541	RING finger protein 113A	EM	2.89	2021-01-14	57.20	81.86	0.48	0.84	16.62	10.26	0.47	wrong
7DVQ_R	Q13573	SNW domain-containing protein 1	EM	2.89	2021-01-14	0.00	83.33	0.62	0.87	16.29	9.73	0.44	ok
7BRJ_L	P01160	Urodilatin	X-ray	2.70	2020-03-29	0.00	60.16	0.20	0.51	27.27	6.79	0.24	ok
7BRH_L	P01160	Natriuretic peptides A	X-ray	2.45	2020-03-29	0.00	59.68	0.17	0.49	30.00	6.98	0.24	ok
6Y9H_L	P00734	Prothrombin	X-ray	1.48	2020-03-09	—	83.94	0.72	—	—	—	0.24	ok
6YB6_L	P00734	Prothrombin	X-ray	1.33	2020-03-16	—	83.94	0.72	—	—	—	0.23	ok
7DVQ_A	Q6P2Q9	Pre-mRNA-processing-splicing factor 8	EM	2.89	2021-01-14	—	84.94	0.74	—	—	—	0.22	ok
7DVQ_5	Q9Y3B4	Splicing factor 3B subunit 6	EM	2.89	2021-01-14	—	90.12	0.75	—	—	—	0.22	ok
7DVQ_P	Q9P013	Spliceosome-associated protein CWC15 homol	EM	2.89	2021-01-14	—	74.88	0.71	—	—	—	0.22	ok
7BRK_L	P01160	Natriuretic peptides A	X-ray	2.85	2020-03-29	0.00	60.26	0.14	0.52	34.78	5.95	0.21	ok
7DVQ_0	Q9P021	Cysteine-rich PDZ-binding protein	EM	2.89	2021-01-14	100.00 novel	78.67	0.66	0.70	42.00	5.24	0.21	ok
7DVQ_2	Q13435	Splicing factor 3B subunit 2	EM	2.89	2021-01-14	—	65.69	0.70	—	—	—	0.20	ok
7BP9_A	P55072	Transitional endoplasmic reticulum ATPase	EM	3.60	2020-03-21	—	82.56	0.79	—	—	—	0.18	ok
7BPA_A	P55072	Transitional endoplasmic reticulum ATPase	EM	3.30	2020-03-21	—	82.56	0.79	—	—	—	0.17	ok
7BP8_A	P55072	Transitional endoplasmic reticulum ATPase	EM	3.90	2020-03-21	—	82.56	0.79	—	—	—	0.17	ok
7DVQ_7	Q9BWJ5	Splicing factor 3B subunit 5	EM	2.89	2021-01-14	—	91.62	0.82	—	—	—	0.17	ok
7BPB_A	P55072	Transitional endoplasmic reticulum ATPase	EM	4.30	2020-03-22	—	82.56	0.80	—	—	—	0.17	ok
7DVQ_Z	Q9BRD0	BUD13 homolog	EM	2.89	2021-01-14	—	59.94	0.74	—	—	—	0.16	ok
7NE0_C	Q6NW40	Repulsive Guidance Molecule B	X-ray	3.25	2021-02-02	3.00	89.47	0.40	0.81	71.67	3.95	0.13	wrong
7NDG_M	Q6NW40	RGM domain family member B	EM	5.98	2021-02-01	2.50	89.47	0.40	0.81	71.67	3.95	0.13	wrong
7DVQ_1	O75533	Splicing factor 3B subunit 1	EM	2.89	2021-01-14	—	74.81	0.84	—	—	—	0.12	ok
7DVQ_K	Q9H6L4	Armadillo repeat-containing protein 7	EM	2.89	2021-01-14	—	88.56	0.87	—	—	—	0.12	ok
7DVQ_4	Q15427	Splicing factor 3B subunit 4	EM	2.89	2021-01-14	—	73.19	0.86	—	—	—	0.10	ok
7DVQ_b	P14678	Small nuclear ribonucleoprotein-associated	EM	2.89	2021-01-14	—	69.50	0.86	—	—	—	0.10	ok
6WA2_A	P00533	Epidermal growth factor receptor	X-ray	2.40	2020-03-24	—	75.94	0.88	—	—	—	0.09	ok
7DVQ_y	Q92917	G-patch domain and KOW motifs-containing p	EM	2.89	2021-01-14	100.00 novel	56.09	0.34	0.77	53.85	2.56	0.09	ok
7KFZ_A	P01116	GTPase KRas	EM	3.47	2020-10-15	—	91.50	0.90	—	—	—	0.09	ok
6W5M_D	Q9UBL3	Set1/Ash2 histone methyltransferase comple	EM	4.60	2020-03-13	—	75.25	0.88	—	—	—	0.09	ok
6W5I_D	Q9UBL3	Set1/Ash2 histone methyltransferase comple	EM	6.90	2020-03-13	—	75.25	0.88	—	—	—	0.09	ok
6WAK_A	P00533	Epidermal growth factor receptor	X-ray	2.40	2020-03-25	—	75.94	0.89	—	—	—	0.09	ok
7D0E_B	Q9ULG6	Cell cycle progression protein 1 FIR2	X-ray	1.40	2020-09-09	—	51.62	0.29	0.68	56.82	2.82	0.09	ok
6W5N_D	Q9UBL3	Set1/Ash2 histone methyltransferase comple	EM	6.00	2020-03-13	—	75.25	0.89	—	—	—	0.09	ok
7KFK_A	Q8NHL6	Isoform 2 of Leukocyte immunoglobulin-like	X-ray	2.63	2020-10-14	—	73.38	0.89	—	—	—	0.08	ok
7DVQ_Y	Q9Y388	RNA-binding motif protein, X-linked 2	EM	2.89	2021-01-14	—	63.66	0.87	—	—	—	0.08	ok
7DVQ_d	P62316	Small nuclear ribonucleoprotein Sm D2	EM	2.89	2021-01-14	—	90.62	0.91	—	—	—	0.08	ok
7DVQ_U	Q9UQ35	Serine/arginine repetitive matrix protein	EM	2.89	2021-01-14	0.00	81.26	0.52	0.83	78.85	2.07	0.08	ok
7DVQ_8	Q8IYB3	Serine/arginine repetitive matrix protein	EM	2.89	2021-01-14	—	51.62	0.87	—	—	—	0.07	ok
7NE0_A	O95631	Netrin-1	X-ray	3.25	2021-02-02	—	88.50	0.93	—	—	—	0.06	ok
6YB6_H	P00734	Prothrombin	X-ray	1.33	2020-03-16	—	83.94	0.92	—	—	—	0.06	ok
6Y9H_H	P00734	Prothrombin	X-ray	1.48	2020-03-09	—	83.94	0.92	—	—	—	0.06	ok
7DFL_R	P35367	Histamine H1 receptor	EM	3.30	2020-11-09	—	69.94	0.91	—	—	—	0.06	ok
7DVQ_x	O60231	Pre-mRNA-splicing factor ATP-dependent RNA	EM	2.89	2021-01-14	—	77.69	0.93	—	—	—	0.06	ok
6Y7J_A	Q9H8M2	Bromodomain-containing protein 9	X-ray	1.60	2020-03-01	—	62.97	0.91	—	—	—	0.06	ok
6Y7K_A	Q9H8M2	Bromodomain-containing protein 9	X-ray	1.20	2020-03-01	—	62.97	0.91	—	—	—	0.06	ok
7KFZ_B	Q07889	Son of sevenless homolog 1	EM	3.47	2020-10-15	—	76.38	0.93	—	—	—	0.06	ok
7NDG_A	O95631	Netrin-1	EM	5.98	2021-02-01	—	88.50	0.94	—	—	—	0.05	ok
6WQU_D	Q9UM47	Neurogenic locus notch homolog protein 3	X-ray	2.41	2020-04-29	—	25.46	0.24	0.74	50.00	3.15	0.05	ok
6Y7I_A	Q9H8M2	Bromodomain-containing protein 9	X-ray	1.60	2020-03-01	—	62.97	0.92	—	—	—	0.05	ok
7NE0_D	Q6NW40	Repulsive Guidance Molecule B C-terminal r	X-ray	3.25	2021-02-02	—	79.44	0.94	—	—	—	0.05	ok
6Y7H_A	Q9H8M2	Bromodomain-containing protein 9	X-ray	1.80	2020-03-01	—	62.97	0.92	—	—	—	0.05	ok
7DWX_B	Q9BYF1	Angiotensin-converting enzyme 2	EM	8.30	2021-01-18	—	90.69	0.95	—	—	—	0.05	ok
6Y7L_A	Q9H8M2	Bromodomain-containing protein 9	X-ray	1.80	2020-03-01	—	62.97	0.92	—	—	—	0.05	ok
7JUP_A	O75762	Transient receptor potential cation channe	EM	3.05	2020-08-20	—	81.94	0.95	—	—	—	0.04	ok
7D0E_A	Q8TDY2	RB1-inducible coiled-coil protein 1	X-ray	1.40	2020-09-09	—	72.50	0.94	—	—	—	0.04	ok
6Y7T_A	P31947	14-3-3 protein sigma	X-ray	2.50	2020-03-02	—	92.88	0.95	—	—	—	0.04	ok
6L71_A	Q8IXJ6	NAD-dependent protein deacetylase sirtuin-	X-ray	2.11	2019-10-30	0.00	92.82	0.98	0.96	95.27	1.00	0.04	ok
7DX9_D	Q9BYF1	Angiotensin-converting enzyme 2	EM	3.60	2021-01-18	—	90.69	0.95	—	—	—	0.04	ok
7DX8_D	Q9BYF1	Angiotensin-converting enzyme 2	EM	2.90	2021-01-18	—	90.69	0.95	—	—	—	0.04	ok
7DX7_D	Q9BYF1	Angiotensin-converting enzyme 2	EM	3.40	2021-01-18	—	90.69	0.95	—	—	—	0.04	ok
7DX6_D	Q9BYF1	Angiotensin-converting enzyme 2	EM	3.00	2021-01-18	—	90.69	0.95	—	—	—	0.04	ok
7DX5_D	Q9BYF1	Angiotensin-converting enzyme 2	EM	3.30	2021-01-18	—	90.69	0.95	—	—	—	0.04	ok
7DVQ_g	P62308	Small nuclear ribonucleoprotein G	EM	2.89	2021-01-14	—	93.25	0.95	—	—	—	0.04	ok
7LO4_A	Q9BYF1	Processed angiotensin-converting enzyme 2	X-ray	2.46	2021-02-09	—	90.69	0.95	—	—	—	0.04	ok
7DVQ_X	Q8TAD8	Smad nuclear-interacting protein 1	EM	2.89	2021-01-14	—	66.06	0.94	—	—	—	0.04	ok
7DVQ_L	Q99459	Cell division cycle 5-like protein	EM	2.89	2021-01-14	—	74.31	0.94	—	—	—	0.04	ok
7DFL_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.30	2020-11-09	—	89.56	0.96	—	—	—	0.04	ok
6L72_A	Q8IXJ6	NAD-dependent protein deacetylase sirtuin-	X-ray	2.50	2019-10-30	0.00	93.02	0.98	0.96	95.66	0.87	0.04	ok
7DVQ_I	Q5RL73	RNA-binding protein 48	EM	2.89	2021-01-14	—	67.75	0.95	—	—	—	0.04	ok
7NDG_C	Q6NW40	Repulsive Guidance Molecule B (C-terminal	EM	5.98	2021-02-01	—	79.44	0.96	—	—	—	0.04	ok
6L23_A	P68400	Casein kinase II subunit alpha	X-ray	1.97	2019-10-02	0.30	97.00	0.99	0.96	96.11	0.91	0.03	ok
7DVQ_a	P62318	Small nuclear ribonucleoprotein Sm D3	EM	2.89	2021-01-14	—	82.81	0.96	—	—	—	0.03	ok
6YDZ_A	Q86WV6	Stimulator of interferon protein	X-ray	2.90	2020-03-23	—	83.75	0.96	—	—	—	0.03	ok
6YE9_A	P31947	14-3-3 protein sigma	X-ray	1.80	2020-03-24	—	92.88	0.97	—	—	—	0.03	ok
7BEV_A	Q07617	Sperm-associated antigen 1	NMR	—	2020-12-29	—	73.69	0.96	—	—	—	0.03	ok
6YDB_A	Q86WV6	Stimulator of interferon protein	X-ray	2.80	2020-03-20	—	83.75	0.97	—	—	—	0.03	ok
6Y99_A	Q86WV6	Stimulator of interferon genes protein	X-ray	2.98	2020-03-06	—	83.75	0.97	—	—	—	0.03	ok
7CZM_A	Q8TDY2	RB1-inducible coiled-coil protein 1	X-ray	2.00	2020-09-09	—	72.50	0.96	—	—	—	0.03	ok
7CZG_A	Q8TDY2	RB1-inducible coiled-coil protein 1	X-ray	1.80	2020-09-08	—	72.50	0.96	—	—	—	0.03	ok
6Y7G_A	Q96E17	Ras-related protein Rab-3C	X-ray	2.30	2020-02-29	—	82.62	0.97	—	—	—	0.03	ok
6YEA_A	Q86WV6	Stimulator of interferon protein	X-ray	2.81	2020-03-24	—	83.75	0.97	—	—	—	0.03	ok
7DVQ_e	P62304	Small nuclear ribonucleoprotein E	EM	2.89	2021-01-14	—	90.75	0.97	—	—	—	0.02	ok
6Y6R_A	Q8N5J2	Ubiquitin carboxyl-terminal hydrolase MIND	X-ray	3.32	2020-02-27	—	72.69	0.97	—	—	—	0.02	ok
7DVQ_f	P62306	Small nuclear ribonucleoprotein F	EM	2.89	2021-01-14	—	90.50	0.98	—	—	—	0.02	ok
7BPH_A	P63092	Guanine nucleotide-binding protein G(s) su	X-ray	1.57	2020-03-22	—	91.31	0.98	—	—	—	0.02	ok
7DWX_A	Q695T7	Sodium-dependent neutral amino acid transp	EM	8.30	2021-01-18	—	90.00	0.98	—	—	—	0.02	ok
7DVQ_C	Q15029	116 kDa U5 small nuclear ribonucleoprotein	EM	2.89	2021-01-14	—	89.94	0.98	—	—	—	0.02	ok
7NE1_A	O95631	Netrin-1	X-ray	3.15	2021-02-02	—	88.50	0.98	—	—	—	0.02	ok
7D2V_A	P56817	Beta-secretase 1	X-ray	2.10	2020-09-17	—	87.50	0.98	—	—	—	0.02	ok
6Y8P_A	E5BBQ0	O6-alkylguanine-DNA alkyltransferase mutan	X-ray	2.30	2020-03-05	—	90.50	0.98	—	—	—	0.02	ok
7DVQ_c	P62314	Small nuclear ribonucleoprotein Sm D1	EM	2.89	2021-01-14	—	82.81	0.98	—	—	—	0.02	ok
7DVQ_3	Q15393	Splicing factor 3B subunit 3	EM	2.89	2021-01-14	—	92.25	0.98	—	—	—	0.02	ok
6W5I_A	Q15291	Retinoblastoma-binding protein 5	EM	6.90	2020-03-13	—	77.75	0.98	—	—	—	0.02	ok
7DVQ_6	Q7RTV0	PHD finger-like domain-containing protein	EM	2.89	2021-01-14	—	89.88	0.98	—	—	—	0.02	ok
6W5N_A	Q15291	Retinoblastoma-binding protein 5	EM	6.00	2020-03-13	—	77.75	0.98	—	—	—	0.01	ok
6XIY_A	Q8IUN9	C-type lectin domain family 10 member A	X-ray	2.31	2020-06-22	—	80.44	0.98	—	—	—	0.01	ok
7DFL_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.30	2020-11-09	—	97.06	0.99	—	—	—	0.01	ok
7DVQ_D	O75643	U5 small nuclear ribonucleoprotein 200 kDa	EM	2.89	2021-01-14	—	82.75	0.98	—	—	—	0.01	ok
7D2X_A	P56817	Beta-secretase 1	X-ray	2.45	2020-09-17	—	87.50	0.99	—	—	—	0.01	ok
6W5M_A	Q15291	Retinoblastoma-binding protein 5	EM	4.60	2020-03-13	—	77.75	0.99	—	—	—	0.01	ok
7D5U_A	Q9Y5Z0	Beta-secretase 2	X-ray	2.04	2020-09-28	—	82.69	0.99	—	—	—	0.01	ok
7D5A_A	P56817	Beta-secretase 1	X-ray	2.20	2020-09-25	—	87.50	0.99	—	—	—	0.01	ok
7LJ9_A	P53396	ATP-citrate synthase	EM	3.00	2021-01-28	—	92.25	0.99	—	—	—	0.01	ok
7DVQ_z	Q6UX04	Peptidyl-prolyl cis-trans isomerase CWC27	EM	2.89	2021-01-14	—	73.56	0.99	—	—	—	0.01	ok
7E4T_A	Q9UL62	Short transient receptor potential channel	EM	3.00	2021-02-15	—	73.19	0.99	—	—	—	0.01	ok
7D4Q_A	Q9UL62	Short transient receptor potential channel	EM	2.74	2020-09-24	—	73.19	0.99	—	—	—	0.01	ok
7D4P_A	Q9UL62	Short transient receptor potential channel	EM	2.70	2020-09-24	—	73.19	0.99	—	—	—	0.01	ok
7JG0_A	P22102	Trifunctional purine biosynthetic protein	X-ray	1.98	2020-07-18	—	92.75	0.99	—	—	—	0.01	ok
6W5N_B	P61964	WD repeat-containing protein 5	EM	6.00	2020-03-13	—	93.31	0.99	—	—	—	0.01	ok
6W5I_B	P61964	WD repeat-containing protein 5	EM	6.90	2020-03-13	—	93.31	0.99	—	—	—	0.01	ok
6W5M_B	P61964	WD repeat-containing protein 5	EM	4.60	2020-03-13	—	93.31	0.99	—	—	—	0.01	ok
7JG3_A	P22102	Trifunctional purine biosynthetic protein	X-ray	2.09	2020-07-18	—	92.75	0.99	—	—	—	0.01	ok
7D5B_A	Q9Y5Z0	Beta-secretase 2	X-ray	1.31	2020-09-25	—	82.69	0.99	—	—	—	0.01	ok
7JG4_A	P22102	Trifunctional purine biosynthetic protein	X-ray	2.46	2020-07-18	—	92.75	0.99	—	—	—	0.01	ok
7DVQ_E	Q96DI7	U5 small nuclear ribonucleoprotein 40 kDa	EM	2.89	2021-01-14	—	85.25	0.99	—	—	—	0.01	ok
7EA9_A	Q15046	Lysine--tRNA ligase	X-ray	2.50	2021-03-06	—	90.50	0.99	—	—	—	0.01	ok
7DVQ_T	O43660	Pleiotropic regulator 1	EM	2.89	2021-01-14	—	77.38	0.99	—	—	—	0.00	ok
6YRI_A	P00918	Carbonic anhydrase 2	X-ray	1.60	2020-04-20	—	97.38	1.00	—	—	—	0.00	ok
6WVO_A	P22303	Acetylcholinesterase	X-ray	2.19	2020-05-06	—	92.94	1.00	—	—	—	0.00	ok

Click a column header to sort. FRAUD = confidence-weighted error; a structure is flagged confidently wrong when mean pLDDT > 70 yet TM-score < 0.5.