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New PDB Depositions vs. Their Blind AlphaFold Predictions — A Running Test of “Is Folding Solved?”

Release week 2021-03-10

152
structures analysed (41 full · 27.0%)
74.6%
confidently wrong
1811.8%
novel sequences
63.9%
novel & wrong
0.901
median TM-score

Zoomed into the red "confidently wrong" box above (pLDDT ≥ 70, TM < 0.5) — the structures AlphaFold got confidently wrong.

The worst offenders ranked, one row per protein (AlphaFold has one model per sequence, so repeat depositions are collapsed — “×N” marks how many structures of that protein exist; the worst is shown). Each row joins what AlphaFold claimed (blue, pLDDT/100) to what the experiment showed (red, TM-score) — the longer the bar, the bigger the miss. Hover a dot to preview its Cα-deviation ribbon; click to open the full entry.

How to read this

Every point is one experimental protein structure. The horizontal axis is AlphaFold's own confidence in its prediction (mean pLDDT, 0–100). The vertical axis is how well that blind prediction actually matches the experiment (TM-score, 0–1; above 0.5 means the same fold, above 0.9 near-identical). Marker size grows with the FRAUD score (confidence-weighted error).

Cutoff: the shaded red box is the "confidently wrong" zone — AlphaFold was confident (mean pLDDT above 70) yet the fold is wrong (TM-score below 0.5). A predictor that had truly solved folding would leave that box empty.

Take-home: 7 of 152 structures (4.6%) are confidently wrong; median TM-score is 0.901.

Read moreShow less — how each metric is calculated

TM-score: how similar the two 3D shapes are overall, 0–1 (a random pair scores ~0.17, an identical fold ~1). Length-normalised so large and small proteins compare fairly. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) — dᵢ is the gap between the i-th aligned Cα atoms after best-fit superposition, and d₀ = 1.24(L−15)^⅓ − 1.8 sets the distance scale for length L. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264; computed with TM-align, doi:10.1093/nar/gki524.

pLDDT: AlphaFold's own confidence in each residue, 0–100 (higher = surer). It is the model predicting its own accuracy before ever seeing the experiment. We plot the per-structure mean. pLDDT = (1/N) Σᵢ pLDDTᵢ, where pLDDTᵢ is the network's confidence output for residue i.

FRAUD score: the headline number — how wrong the prediction was, weighted by how confident AlphaFold was, so a big error it was sure about counts most. FRAUD = (1/N) Σᵢ (pLDDTᵢ/100) · min(Δᵢ,15)/15, where Δᵢ is residue i's Cα distance from the experiment (Å) after superposition, capped at 15 Å. Runs 0 (perfect) to 1.

Novelty: how little AlphaFold had to go on — 100 minus the highest sequence identity between this protein and any structure released before the 2018-04-30 training cutoff. High = genuinely unseen (100% = nothing similar was ever in the training set). novelty = 100 − maxₚ identity(s, p) over pre-cutoff PDB chains p, with identity = 100 × (matching aligned residues)/(alignment length), from an MMseqs2 search.

Homology: the point colour. High novelty (above 70%) flags the sequence as novel (amber) — AlphaFold had no close template; otherwise a pre-cutoff homolog existed (blue) it could have learned the fold from. novel ⇔ novelty > 70%.

What the metrics mean

TM-score (0–1): overall fold match — above 0.5 is the same fold, above 0.9 near-identical. Cα-RMSD (Å): average backbone distance after best-fit superposition — lower is better (under 2 Å is excellent). lDDT (0–1): local accuracy measured without superposition — above 0.8 is good. Each bar counts how many structures fall in that range.

Take-home: median TM-score 0.901 — most predictions match the experimental fold well, with a long tail that do not.

Read moreShow less — how each metric is calculated

TM-score: overall shape match, 0–1 (above 0.5 = same fold, above 0.9 near-identical), length-normalised. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) with dᵢ the aligned-Cα gap after superposition and d₀ = 1.24(L−15)^⅓ − 1.8. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264.

Cα-RMSD: the average straight-line distance between matching backbone Cα atoms once the two structures are best-fit superposed (Å; lower is better, under ~2 Å excellent). RMSD = √( (1/N) Σᵢ |Pᵢ − (R·Qᵢ + t)|² ), with Pᵢ/Qᵢ the experimental/model Cα coordinates and R,t the rotation and translation from Kabsch superposition.

lDDT: local accuracy with no superposition — the fraction of short-range inter-residue distances the model reproduces, so it is not fooled by a single wrongly-placed domain. lDDT = (1/N) Σᵢ ¼ Σ_t 1[ |d_exp − d_model| < t ] over thresholds t ∈ {0.5, 1, 2, 4} Å and all residue pairs within 15 Å.

Trend over time

The blue line is the mean TM-score of the structures by their deposit month; the red bars count how many were confidently wrong. Binning by deposit date (rather than by when we processed them) gives an even timeline, tracking whether AlphaFold's accuracy on newly-deposited structures is holding steady, improving, or slipping as the PDB keeps growing. Months with fewer than 5 structures are omitted so each point is a meaningful average. A dashed trend line is drawn only if the change over time is statistically significant.

Read moreShow less — how each metric is calculated

Mean TM-score: the month's average shape-match score. TM̄ = (1/M) Σ TM over the M structures deposited that month.

Trend line: a monotonic-trend test over the monthly means — Mann-Kendall (Kendall's τ) for significance, with a robust Theil-Sen slope for the line. Rank-based, so it tolerates the skewed TM distribution and noisy low-count months. Shown only when p < 0.05; otherwise a note reports that no significant trend was found.

Confidently wrong: the count that were both confident and wrong. count( mean pLDDT > 70 AND TM < 0.5 ).

Matched structures

PDBUniProtProteinMethodÅDeposited Novelty %pLDDTTMlDDTGDT_TSRMSDFRAUDFlag
7KZS_E Q9HB96 Fanconi anemia group E protein EM 4.20 2020-12-10 0.40 86.70 0.58 0.85 0.18 52.72 0.86 ok
7KZR_E Q9HB96 Fanconi anemia group E protein EM 4.40 2020-12-10 0.40 86.70 0.57 0.85 0.18 53.09 0.86 ok
7KZQ_E Q9HB96 Fanconi anemia group E protein EM 4.30 2020-12-10 0.40 86.70 0.57 0.87 0.24 52.83 0.86 ok
7KZT_E Q9HB96 Fanconi anemia group E protein EM 4.20 2020-12-10 0.40 86.70 0.58 0.85 0.18 52.74 0.86 ok
7KZV_E Q9HB96 Fanconi anemia group E protein EM 4.20 2020-12-10 0.40 86.70 0.56 0.85 0.24 53.00 0.86 ok
7KZS_A O15360 Fanconi anemia group A protein EM 4.20 2020-12-10 100.00 novel 78.51 0.60 0.80 1.08 35.08 0.75 ok
7KZT_A O15360 Fanconi anemia group A protein EM 4.20 2020-12-10 100.00 novel 78.51 0.60 0.79 1.08 35.06 0.75 ok
7KZP_A O15360 Fanconi anemia group A protein EM 3.10 2020-12-10 100.00 novel 78.51 0.60 0.79 1.14 34.31 0.75 ok
7KZV_A O15360 Fanconi anemia group A protein EM 4.20 2020-12-10 100.00 novel 78.51 0.60 0.79 1.12 35.07 0.75 ok
7KZQ_A O15360 Fanconi anemia group A protein EM 4.30 2020-12-10 100.00 novel 78.51 0.60 0.79 1.10 34.78 0.75 ok
7KZR_A O15360 Fanconi anemia group A protein EM 4.40 2020-12-10 100.00 novel 78.51 0.61 0.78 1.18 34.53 0.75 ok
7KZV_B Q8NB91 Fanconi anemia group B protein EM 4.20 2020-12-10 100.00 novel 78.02 0.47 0.81 1.18 31.78 0.74 wrong
7KZT_B Q8NB91 Fanconi anemia group B protein EM 4.20 2020-12-10 100.00 novel 78.02 0.47 0.81 1.21 31.73 0.74 wrong
7KZS_B Q8NB91 Fanconi anemia group B protein EM 4.20 2020-12-10 100.00 novel 78.02 0.47 0.81 1.18 31.73 0.74 wrong
7KZP_B Q8NB91 Fanconi anemia group B protein EM 3.10 2020-12-10 100.00 novel 78.02 0.47 0.82 1.21 31.65 0.74 wrong
7KZQ_B Q8NB91 Fanconi anemia group B protein EM 4.30 2020-12-10 100.00 novel 78.02 0.47 0.81 1.21 31.81 0.74 wrong
7KZR_B Q8NB91 Fanconi anemia group B protein EM 4.40 2020-12-10 100.00 novel 78.02 0.47 0.79 1.28 31.84 0.74 wrong
7LBF_D P16234 Isoform 3 of Platelet-derived growth facto EM 2.80 2021-01-07 68.30 82.72 0.63 0.87 6.84 13.90 0.62 ok
7KZR_L Q9NW38 E3 ubiquitin-protein ligase FANCL EM 4.40 2020-12-10 0.00 91.94 0.58 0.85 10.74 13.64 0.60 ok
7KZT_L Q9NW38 E3 ubiquitin-protein ligase FANCL EM 4.20 2020-12-10 0.00 91.94 0.58 0.86 11.15 13.64 0.59 ok
7KZS_L Q9NW38 E3 ubiquitin-protein ligase FANCL EM 4.20 2020-12-10 0.00 91.94 0.58 0.87 10.95 13.63 0.59 ok
7KZV_L Q9NW38 E3 ubiquitin-protein ligase FANCL EM 4.20 2020-12-10 0.00 91.94 0.58 0.87 11.22 13.60 0.59 ok
7KZQ_L Q9NW38 E3 ubiquitin-protein ligase FANCL EM 4.30 2020-12-10 0.00 91.94 0.58 0.88 11.01 13.56 0.59 ok
7KZP_L Q9NW38 E3 ubiquitin-protein ligase FANCL EM 3.10 2020-12-10 0.00 91.94 0.58 0.88 11.28 13.52 0.59 ok
7DM4_A Q4LE39 AT-rich interactive domain-containing prot NMR 2020-12-02 19.70 77.35 0.43 0.71 6.46 15.57 0.56 wrong
7KZS_P Q0VG06 Fanconi anemia core complex-associated pro EM 4.20 2020-12-10 100.00 novel 79.81 0.60 0.79 14.37 15.50 0.52 ok
7KZT_P Q0VG06 Fanconi anemia core complex-associated pro EM 4.20 2020-12-10 100.00 novel 79.81 0.60 0.78 14.54 15.41 0.52 ok
7KZP_P Q0VG06 Fanconi anemia core complex-associated pro EM 3.10 2020-12-10 100.00 novel 79.81 0.60 0.80 14.94 15.39 0.52 ok
7KZV_P Q0VG06 Fanconi anemia core complex-associated pro EM 4.20 2020-12-10 100.00 novel 79.81 0.60 0.78 15.04 15.43 0.52 ok
7KZQ_P Q0VG06 Fanconi anemia core complex-associated pro EM 4.30 2020-12-10 100.00 novel 79.81 0.60 0.79 15.11 15.42 0.52 ok
7KZR_P Q0VG06 Fanconi anemia core complex-associated pro EM 4.40 2020-12-10 100.00 novel 79.81 0.60 0.77 14.71 15.38 0.51 ok
7KZR_F Q9NPI8 Fanconi anemia group F protein EM 4.40 2020-12-10 0.00 82.27 0.66 0.81 32.72 5.89 0.27 ok
7KZS_F Q9NPI8 Fanconi anemia group F protein EM 4.20 2020-12-10 0.00 82.27 0.67 0.81 33.01 5.87 0.27 ok
7KZV_F Q9NPI8 Fanconi anemia group F protein EM 4.20 2020-12-10 0.00 82.27 0.66 0.81 33.90 5.87 0.27 ok
7KZT_F Q9NPI8 Fanconi anemia group F protein EM 4.20 2020-12-10 0.00 82.27 0.67 0.82 33.53 5.87 0.27 ok
7KZP_F Q9NPI8 Fanconi anemia group F protein EM 3.10 2020-12-10 0.00 82.27 0.67 0.83 33.53 5.87 0.27 ok
7KZQ_F Q9NPI8 Fanconi anemia group F protein EM 4.30 2020-12-10 0.00 82.27 0.67 0.83 33.90 5.82 0.27 ok
7NMU_AAA Q9HCN6 Platelet glycoprotein VI X-ray 2.50 2021-02-23 76.06 0.71 0.22 ok
7K36_A P30153 Serine/threonine-protein phosphatase 2A 65 EM 3.30 2020-09-10 94.94 0.77 0.22 ok
7KZV_V Q9BXW9 Fanconi anemia group D2 protein EM 4.20 2020-12-10 76.75 0.76 0.19 ok
7KZP_E Q9HB96 Fanconi anemia group E protein EM 3.10 2020-12-10 76.00 0.77 0.18 ok
7KZS_V Q9BXW9 Fanconi anemia group D2 protein EM 4.20 2020-12-10 76.75 0.77 0.17 ok
7CMU_A P63096 Guanine nucleotide-binding protein G(i) su EM 3.00 2020-07-29 93.75 0.82 0.17 ok
7CMV_A P63096 Guanine nucleotide-binding protein G(i) su EM 2.70 2020-07-29 93.75 0.82 0.16 ok
7KZT_V Q9BXW9 Fanconi anemia group D2 protein EM 4.20 2020-12-10 76.75 0.80 0.15 ok
7LWB_D Q969X0 RILP-like protein 2 X-ray 1.90 2021-02-28 77.19 0.81 0.15 ok
7DTV_A P41180 Extracellular calcium-sensing receptor EM 3.50 2021-01-06 75.69 0.82 0.14 ok
7DTT_A P41180 Extracellular calcium-sensing receptor EM 3.80 2021-01-06 75.69 0.82 0.14 ok
7KZQ_V Q9BXW9 Fanconi anemia group D2 protein EM 4.30 2020-12-10 76.75 0.82 0.13 ok
7KZR_V Q9BXW9 Fanconi anemia group D2 protein EM 4.40 2020-12-10 76.75 0.83 0.13 ok
6W2G_A P54725 UV excision repair protein RAD23 homolog A X-ray 1.10 2020-03-05 69.38 0.82 0.13 ok
6W2I_A P54725 UV excision repair protein RAD23 homolog A X-ray 1.45 2020-03-05 69.38 0.82 0.13 ok
7JXU_A Q8NB16 Mixed lineage kinase domain-like protein X-ray 2.44 2020-08-28 83.12 0.85 0.12 ok
6W2H_A P54725 UV excision repair protein RAD23 homolog A X-ray 1.60 2020-03-05 69.38 0.83 0.12 ok
6X6A_C Q9C000 NACHT, LRR and PYD domains-containing prot EM 3.60 2020-05-27 68.25 0.83 0.12 ok
7KZP_G O15287 Fanconi anemia group G protein EM 3.10 2020-12-10 83.12 0.87 0.11 ok
7KZS_G O15287 Fanconi anemia group G protein EM 4.20 2020-12-10 83.12 0.87 0.11 ok
7KZT_G O15287 Fanconi anemia group G protein EM 4.20 2020-12-10 83.12 0.87 0.11 ok
7KZR_G O15287 Fanconi anemia group G protein EM 4.40 2020-12-10 83.12 0.87 0.11 ok
7KZV_G O15287 Fanconi anemia group G protein EM 4.20 2020-12-10 83.12 0.87 0.11 ok
7KZQ_G O15287 Fanconi anemia group G protein EM 4.30 2020-12-10 83.12 0.87 0.11 ok
7DSQ_B Q01650 Large neutral amino acids transporter smal EM 3.40 2020-12-31 85.88 0.88 0.10 ok
7KZQ_C Q00597 Fanconi anemia group C protein EM 4.30 2020-12-10 82.06 0.88 0.10 ok
7KZR_C Q00597 Fanconi anemia group C protein EM 4.40 2020-12-10 82.06 0.88 0.10 ok
7KZS_C Q00597 Fanconi anemia group C protein EM 4.20 2020-12-10 82.06 0.88 0.10 ok
7KZV_C Q00597 Fanconi anemia group C protein EM 4.20 2020-12-10 82.06 0.88 0.10 ok
7KZT_C Q00597 Fanconi anemia group C protein EM 4.20 2020-12-10 82.06 0.88 0.10 ok
7KZP_C Q00597 Fanconi anemia group C protein EM 3.10 2020-12-10 82.06 0.88 0.10 ok
7DTW_A P41180 Extracellular calcium-sensing receptor EM 4.50 2021-01-06 75.69 0.88 0.09 ok
7LFT_A P29973 cGMP-gated cation channel alpha-1 EM 2.60 2021-01-18 76.25 0.88 0.09 ok
7DSN_B Q01650 Large neutral amino acids transporter smal EM 3.10 2020-12-31 85.88 0.90 0.09 ok
7CMU_C P59768 Guanine nucleotide-binding protein G(I)/G( EM 3.00 2020-07-29 89.56 0.90 0.09 ok
7DSK_B Q01650 Large neutral amino acids transporter smal EM 2.90 2020-12-31 85.88 0.90 0.08 ok
7DTU_A P41180 Extracellular calcium-sensing receptor EM 4.40 2021-01-06 75.69 0.89 0.08 ok
6X6C_E Q9C000 NACHT, LRR and PYD domains-containing prot EM 2.90 2020-05-27 68.25 0.88 0.08 ok
7DSL_B Q01650 Large neutral amino acids transporter smal EM 2.90 2020-12-31 85.88 0.90 0.08 ok
6X6A_B Q9C000 NACHT, LRR and PYD domains-containing prot EM 3.60 2020-05-27 68.25 0.88 0.08 ok
7KXY_B P12259 Coagulation factor Va EM 4.40 2020-12-05 61.91 0.87 0.08 ok
6XOG_C P63165 Small ubiquitin-related modifier 1 X-ray 1.98 2020-07-07 78.31 0.90 0.08 ok
7CMV_C P59768 Guanine nucleotide-binding protein G(I)/G( EM 2.70 2020-07-29 89.56 0.93 0.07 ok
7LG1_A P29973 cGMP-gated cation channel alpha-1 EM 2.70 2021-01-19 76.25 0.92 0.06 ok
7LFY_A P29973 cGMP-gated cation channel alpha-1 EM 3.60 2021-01-19 76.25 0.92 0.06 ok
7LFX_A P29973 cGMP-gated cation channel alpha-1 EM 3.10 2021-01-19 76.25 0.92 0.06 ok
7LFW_A P29973 cGMP-gated cation channel alpha-1 EM 2.90 2021-01-18 76.25 0.92 0.06 ok
6M4I_A Q02224 Centromere-associated protein E X-ray 1.90 2020-03-07 1.80 86.21 0.95 0.89 90.11 2.43 0.06 ok
6M4R_A P02768 Serum albumin X-ray 2.49 2020-03-09 0.00 95.12 0.98 0.94 91.62 1.19 0.06 ok
7KXY_A P12259 Coagulation factor Va EM 4.40 2020-12-05 61.91 0.91 0.05 ok
7K3I_A P50120 Retinol-binding protein 2 X-ray 1.20 2020-09-11 96.50 0.95 0.05 ok
6XFP_A P15056 Serine/threonine-protein kinase B-raf X-ray 2.00 2020-06-16 66.38 0.93 0.05 ok
6M1K_A Q93009 Ubiquitin carboxyl-terminal hydrolase 7 X-ray 2.25 2020-02-26 0.00 91.95 0.97 0.92 91.72 1.32 0.05 ok
7KVE_B P12259 Coagulation factor V EM 3.30 2020-11-27 61.91 0.92 0.05 ok
7NDL_A Q06210 Isoform 2 of Glutamine-fructose-6-phosphat X-ray 2.22 2021-02-02 92.88 0.95 0.05 ok
7K36_H Q9Y3A3 MOB-like protein phocein EM 3.30 2020-09-10 90.81 0.95 0.04 ok
7LD0_A Q6SZW1 NAD(+) hydrolase SARM1 EM 3.10 2021-01-12 85.69 0.95 0.04 ok
6UGK_A Q9H6P5 Threonine aspartase 1,Threonine aspartase X-ray 2.15 2019-09-26 0.00 95.77 0.54 0.94 95.31 2.19 0.04 ok
7LMT_A O96028 Histone-lysine N-methyltransferase NSD2 X-ray 2.27 2021-02-05 65.62 0.94 0.04 ok
7KZR_X Q9NPD8 Ubiquitin-conjugating enzyme E2 T EM 4.40 2020-12-10 86.25 0.96 0.04 ok
7K36_I Q5VSL9 Striatin-interacting protein 1 EM 3.30 2020-09-10 80.88 0.95 0.04 ok
7JW7_A Q8NB16 Mixed lineage kinase domain-like protein X-ray 2.63 2020-08-25 83.12 0.96 0.04 ok
7KZV_X Q9NPD8 Ubiquitin-conjugating enzyme E2 T EM 4.20 2020-12-10 86.25 0.96 0.04 ok
7KZT_X Q9NPD8 Ubiquitin-conjugating enzyme E2 T EM 4.20 2020-12-10 86.25 0.96 0.03 ok
7KZS_X Q9NPD8 Ubiquitin-conjugating enzyme E2 T EM 4.20 2020-12-10 86.25 0.96 0.03 ok
7B51_B P62826 GTP-binding nuclear protein Ran X-ray 2.58 2020-12-03 88.62 0.97 0.03 ok
7JWR_A P50120 Retinol-binding protein 2 X-ray 1.30 2020-08-26 96.50 0.97 0.03 ok
7AD6_A P01031 Complement C5 X-ray 2.75 2020-09-14 81.56 0.97 0.03 ok
7JX2_A P50120 Retinol-binding protein 2 X-ray 1.80 2020-08-26 96.50 0.97 0.03 ok
6YF2_A P62942 Peptidyl-prolyl cis-trans isomerase FKBP1A X-ray 1.03 2020-03-25 96.25 0.97 0.03 ok
6YF3_A P62942 Peptidyl-prolyl cis-trans isomerase FKBP1A X-ray 1.00 2020-03-25 96.25 0.97 0.03 ok
7DUO_B P28907 ADP-ribosyl cyclase/cyclic ADP-ribose hydr X-ray 2.81 2021-01-10 90.88 0.97 0.03 ok
7JWD_A P50120 Retinol-binding protein 2 X-ray 1.35 2020-08-25 96.50 0.97 0.03 ok
7LWB_A P61006 Ras-related protein Rab-8A X-ray 1.90 2021-02-28 85.44 0.97 0.02 ok
7BEQ_A Q99836 Myeloid differentiation primary response p EM 3.00 2020-12-24 80.56 0.97 0.02 ok
7DSN_A P08195 4F2 cell-surface antigen heavy chain EM 3.10 2020-12-31 78.69 0.97 0.02 ok
7DSQ_A P08195 4F2 cell-surface antigen heavy chain EM 3.40 2020-12-31 78.69 0.97 0.02 ok
7DSL_A P08195 4F2 cell-surface antigen heavy chain EM 2.90 2020-12-31 78.69 0.98 0.02 ok
7JVG_A P50120 Retinol-binding protein 2 X-ray 1.40 2020-08-21 96.50 0.98 0.02 ok
7DSK_A P08195 4F2 cell-surface antigen heavy chain EM 2.90 2020-12-31 78.69 0.98 0.02 ok
7AEL_AAA P01009 Alpha-1-antitrypsin X-ray 1.76 2020-09-17 88.62 0.98 0.02 ok
7L6W_A Q99836 Myeloid differentiation primary response p X-ray 2.30 2020-12-24 80.56 0.98 0.02 ok
7JZ5_A P50120 Retinol-binding protein 2 X-ray 1.57 2020-09-01 96.50 0.98 0.02 ok
7KPL_A P54762 Ephrin type-B receptor 1 X-ray 2.71 2020-11-11 83.62 0.98 0.02 ok
7BER_A Q99836 Myeloid differentiation primary response p X-ray 2.30 2020-12-24 80.56 0.98 0.02 ok
6W12_A Q8IUN9 C-type lectin domain family 10 member A X-ray 2.00 2020-03-03 80.44 0.98 0.02 ok
6YF1_A P62942 Peptidyl-prolyl cis-trans isomerase FKBP1A X-ray 1.12 2020-03-25 96.25 0.98 0.02 ok
7JVY_A P50120 Retinol-binding protein 2 X-ray 1.30 2020-08-24 96.50 0.98 0.02 ok
7LBG_D Q03167 Transforming growth factor beta receptor t EM 2.60 2021-01-07 71.00 0.98 0.02 ok
6XOG_B Q9UBT2 SUMO-activating enzyme subunit 2 X-ray 1.98 2020-07-07 85.25 0.98 0.02 ok
7DCZ_A P56817 Beta-secretase 1 X-ray 2.30 2020-10-27 87.50 0.98 0.02 ok
7KPM_A P54762 Ephrin type-B receptor 1 X-ray 1.61 2020-11-11 83.62 0.98 0.02 ok
7K36_B Q13033 Striatin-3 EM 3.30 2020-09-10 67.50 0.98 0.02 ok
6WPE_A P14902 Indoleamine 2,3-dioxygenase 1 X-ray 2.43 2020-04-27 93.06 0.98 0.01 ok
6XOG_A Q9UBE0 SUMO-activating enzyme subunit 1 X-ray 1.98 2020-07-07 91.44 0.99 0.01 ok
6YF0_A P62942 Peptidyl-prolyl cis-trans isomerase FKBP1A X-ray 1.55 2020-03-25 96.25 0.99 0.01 ok
7K36_C P67775 Serine/threonine-protein phosphatase 2A ca EM 3.30 2020-09-10 95.06 0.99 0.01 ok
7AD7_A P01031 Complement C5 X-ray 2.30 2020-09-14 81.56 0.99 0.01 ok
6WHE_A P61006 Ras-related protein Rab-8A X-ray 1.73 2020-04-08 85.44 0.99 0.01 ok
6X6C_A Q86TI2 Dipeptidyl peptidase 9 EM 2.90 2020-05-27 92.50 0.99 0.01 ok
7CMU_B P62873 Guanine nucleotide-binding protein G(I)/G( EM 3.00 2020-07-29 97.06 0.99 0.01 ok
6X6A_A Q86TI2 Dipeptidyl peptidase 9 EM 3.60 2020-05-27 92.50 0.99 0.01 ok
7CMV_B P62873 Guanine nucleotide-binding protein G(I)/G( EM 2.70 2020-07-29 97.06 0.99 0.01 ok
7B51_A O14980 Exportin-1 X-ray 2.58 2020-12-03 91.44 0.99 0.01 ok
7KJ0_A P32119 Peroxiredoxin-2 X-ray 2.29 2020-10-25 97.75 1.00 0.00 ok
7KJ1_A P32119 Peroxiredoxin-2 X-ray 2.15 2020-10-25 97.75 1.00 0.00 ok
7KIZ_A P32119 Peroxiredoxin-2 X-ray 1.70 2020-10-25 97.75 1.00 0.00 ok
6ZYF_A Q6P988 Palmitoleoyl-protein carboxylesterase NOTU X-ray 2.19 2020-07-31 83.94 1.00 0.00 ok
7KEN_A P18031 Tyrosine-protein phosphatase non-receptor X-ray 1.80 2020-10-11 81.25 1.00 0.00 ok
7KG0_A Q86W56 Poly(ADP-ribose) glycohydrolase X-ray 1.66 2020-10-15 68.25 1.00 0.00 ok
7KG8_A Q86W56 Poly(ADP-ribose) glycohydrolase X-ray 1.43 2020-10-16 68.25 1.00 0.00 ok
7KG1_A Q86W56 Poly(ADP-ribose) glycohydrolase X-ray 1.65 2020-10-15 68.25 1.00 0.00 ok
7KG6_A Q86W56 Poly(ADP-ribose) glycohydrolase X-ray 1.96 2020-10-16 68.25 1.00 0.00 ok
7KFP_A Q86W56 Poly(ADP-ribose) glycohydrolase X-ray 1.90 2020-10-14 68.25 1.00 0.00 ok
7KG7_A Q86W56 Poly(ADP-ribose) glycohydrolase X-ray 1.85 2020-10-16 68.25 1.00 0.00 ok

Click a column header to sort. FRAUD = confidence-weighted error; a structure is flagged confidently wrong when mean pLDDT > 70 yet TM-score < 0.5.