Release week 2021-03-03

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133

structures analysed (17 full · 12.8%)

10.8%

confidently wrong

53.8%

novel sequences

10.8%

novel & wrong

0.961

median TM-score

⭐ This week's notable releases

5 novel sequences, 1 confidently wrong. Highlight: UV radiation resistance-associated gene protein.

PDB	Protein	Flags	Why it matters
7BL1_AAA ↗	UV radiation resistance-associated gene protein	novel · 100% confidently wrong	Genuinely unseen sequence (0% identity to anything AlphaFold trained on) — and AlphaFold got the fold wrong despite high confidence.
6WW9_X ↗	Shieldin complex subunit 3	novel · 100%	Genuinely unseen sequence (0% identity to anything AlphaFold trained on).
6M3I_A ↗	Histone PARylation factor 1	novel · 100%	Genuinely unseen sequence (0% identity to anything AlphaFold trained on) — AlphaFold predicted it correctly (TM 0.99).
6M3G_A ↗	Histone PARylation factor 1	novel · 100%	Genuinely unseen sequence (0% identity to anything AlphaFold trained on) — AlphaFold predicted it correctly (TM 1.00).
7BL1_CCC ↗	Phosphoinositide 3-kinase regulatory subunit 4	novel · 73%	Genuinely unseen sequence (27% identity to anything AlphaFold trained on).

see all 133 structures ↓

Zoomed into the red "confidently wrong" box above (pLDDT ≥ 70, TM < 0.5) — the structures AlphaFold got confidently wrong.

The worst offenders ranked, one row per protein (AlphaFold has one model per sequence, so repeat depositions are collapsed — “×N” marks how many structures of that protein exist; the worst is shown). Each row joins what AlphaFold claimed (blue, pLDDT/100) to what the experiment showed (red, TM-score) — the longer the bar, the bigger the miss. Hover a dot to preview its Cα-deviation ribbon; click to open the full entry.

How to read this

Every point is one experimental protein structure. The horizontal axis is AlphaFold's own confidence in its prediction (mean pLDDT, 0–100). The vertical axis is how well that blind prediction actually matches the experiment (TM-score, 0–1; above 0.5 means the same fold, above 0.9 near-identical). Marker size grows with the FRAUD score (confidence-weighted error).

Cutoff: the shaded red box is the "confidently wrong" zone — AlphaFold was confident (mean pLDDT above 70) yet the fold is wrong (TM-score below 0.5). A predictor that had truly solved folding would leave that box empty.

Take-home: 1 of 133 structures (0.8%) are confidently wrong; median TM-score is 0.961.

Read moreShow less — how each metric is calculated

TM-score: how similar the two 3D shapes are overall, 0–1 (a random pair scores ~0.17, an identical fold ~1). Length-normalised so large and small proteins compare fairly. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) — dᵢ is the gap between the i-th aligned Cα atoms after best-fit superposition, and d₀ = 1.24(L−15)^⅓ − 1.8 sets the distance scale for length L. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264; computed with TM-align, doi:10.1093/nar/gki524.

pLDDT: AlphaFold's own confidence in each residue, 0–100 (higher = surer). It is the model predicting its own accuracy before ever seeing the experiment. We plot the per-structure mean. pLDDT = (1/N) Σᵢ pLDDTᵢ, where pLDDTᵢ is the network's confidence output for residue i.

FRAUD score: the headline number — how wrong the prediction was, weighted by how confident AlphaFold was, so a big error it was sure about counts most. FRAUD = (1/N) Σᵢ (pLDDTᵢ/100) · min(Δᵢ,15)/15, where Δᵢ is residue i's Cα distance from the experiment (Å) after superposition, capped at 15 Å. Runs 0 (perfect) to 1.

Novelty: how little AlphaFold had to go on — 100 minus the highest sequence identity between this protein and any structure released before the 2018-04-30 training cutoff. High = genuinely unseen (100% = nothing similar was ever in the training set). novelty = 100 − maxₚ identity(s, p) over pre-cutoff PDB chains p, with identity = 100 × (matching aligned residues)/(alignment length), from an MMseqs2 search.

Homology: the point colour. High novelty (above 70%) flags the sequence as novel (amber) — AlphaFold had no close template; otherwise a pre-cutoff homolog existed (blue) it could have learned the fold from. novel ⇔ novelty > 70%.

What the metrics mean

TM-score (0–1): overall fold match — above 0.5 is the same fold, above 0.9 near-identical. Cα-RMSD (Å): average backbone distance after best-fit superposition — lower is better (under 2 Å is excellent). lDDT (0–1): local accuracy measured without superposition — above 0.8 is good. Each bar counts how many structures fall in that range.

Take-home: median TM-score 0.961 — most predictions match the experimental fold well, with a long tail that do not.

Read moreShow less — how each metric is calculated

TM-score: overall shape match, 0–1 (above 0.5 = same fold, above 0.9 near-identical), length-normalised. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) with dᵢ the aligned-Cα gap after superposition and d₀ = 1.24(L−15)^⅓ − 1.8. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264.

Cα-RMSD: the average straight-line distance between matching backbone Cα atoms once the two structures are best-fit superposed (Å; lower is better, under ~2 Å excellent). RMSD = √( (1/N) Σᵢ |Pᵢ − (R·Qᵢ + t)|² ), with Pᵢ/Qᵢ the experimental/model Cα coordinates and R,t the rotation and translation from Kabsch superposition.

lDDT: local accuracy with no superposition — the fraction of short-range inter-residue distances the model reproduces, so it is not fooled by a single wrongly-placed domain. lDDT = (1/N) Σᵢ ¼ Σ_t 1[ |d_exp − d_model| < t ] over thresholds t ∈ {0.5, 1, 2, 4} Å and all residue pairs within 15 Å.

Trend over time

The blue line is the mean TM-score of the structures by their deposit month; the red bars count how many were confidently wrong. Binning by deposit date (rather than by when we processed them) gives an even timeline, tracking whether AlphaFold's accuracy on newly-deposited structures is holding steady, improving, or slipping as the PDB keeps growing. Months with fewer than 5 structures are omitted so each point is a meaningful average. A dashed trend line is drawn only if the change over time is statistically significant.

Read moreShow less — how each metric is calculated

Mean TM-score: the month's average shape-match score. TM̄ = (1/M) Σ TM over the M structures deposited that month.

Trend line: a monotonic-trend test over the monthly means — Mann-Kendall (Kendall's τ) for significance, with a robust Theil-Sen slope for the line. Rank-based, so it tolerates the skewed TM distribution and noisy low-count months. Shown only when p < 0.05; otherwise a note reports that no significant trend was found.

Confidently wrong: the count that were both confident and wrong. count( mean pLDDT > 70 AND TM < 0.5 ).

Matched structures

PDB	UniProt	Protein	Method	Å	Deposited	Novelty %	pLDDT	TM	lDDT	GDT_TS	RMSD	FRAUD	Flag
7BL1_AAA	Q9P2Y5	UV radiation resistance-associated gene pr	EM	9.80	2021-01-17	100.00 novel	88.01	0.40	0.58	1.45	18.40	0.78	wrong
7BL1_BBB	Q8NEB9	Phosphatidylinositol 3-kinase catalytic su	EM	9.80	2021-01-17	0.00	87.57	0.66	0.62	2.80	24.97	0.72	ok
7BL1_CCC	Q99570	Phosphoinositide 3-kinase regulatory subun	EM	9.80	2021-01-17	73.30 novel	83.24	0.58	0.49	6.14	18.04	0.65	ok
7JMY_A	Q15059	Bromodomain-containing protein 3	NMR	—	2020-08-03	0.00	73.84	0.66	0.73	9.90	13.12	0.44	ok
7BL1_EEE	Q14457	Beclin-1	EM	9.80	2021-01-17	—	76.56	0.71	—	—	—	0.22	ok
6WLH_A	P19544	Wilms tumor protein	NMR	—	2020-04-20	0.00	86.93	0.63	0.85	43.43	4.30	0.22	ok
7KLO_A	P29375	Lysine-specific demethylase 5A	NMR	—	2020-10-30	0.00	79.21	0.61	0.65	45.34	5.63	0.20	ok
7KLR_B	P68431	Histone H3.1	NMR	—	2020-10-31	—	62.57	0.51	0.48	30.00	4.23	0.17	ok
7LKZ_A	P78363	Retinal-specific phospholipid-transporting	EM	3.27	2021-02-03	—	75.69	0.78	—	—	—	0.17	ok
7LSZ_A	P07900	Heat shock protein HSP 90-alpha	X-ray	1.70	2021-02-18	—	85.19	0.82	—	—	—	0.16	ok
7CKY_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.20	2020-07-20	—	89.56	0.83	—	—	—	0.16	ok
7LT0_A	P07900	Heat shock protein HSP 90-alpha	X-ray	1.70	2021-02-18	—	85.19	0.82	—	—	—	0.16	ok
7KLR_A	P29375	Lysine-specific demethylase 5A	NMR	—	2020-10-31	0.00	79.21	0.62	0.67	56.36	4.13	0.15	ok
7CKZ_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.10	2020-07-20	—	89.56	0.83	—	—	—	0.15	ok
7CKW_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.22	2020-07-20	—	89.56	0.83	—	—	—	0.15	ok
7LJD_A	P63092	Engineered Gs protein alpha subunit	EM	3.20	2021-01-28	—	91.31	0.85	—	—	—	0.13	ok
7CKZ_A	P63092	Guanine nucleotide-binding protein G(s) su	EM	3.10	2020-07-20	—	91.31	0.86	—	—	—	0.13	ok
7CKY_A	P63092	Guanine nucleotide-binding protein G(s) su	EM	3.20	2020-07-20	—	91.31	0.86	—	—	—	0.13	ok
7LJC_A	P63092	Engineered human Gs alpha subunit	EM	3.00	2021-01-28	—	91.31	0.86	—	—	—	0.13	ok
7CKW_A	P63092	Guanine nucleotide-binding protein G(s) su	EM	3.22	2020-07-20	—	91.31	0.86	—	—	—	0.13	ok
7CRH_A	P63092	Guanine nucleotide-binding protein G(s) su	EM	3.30	2020-08-13	—	91.31	0.86	—	—	—	0.12	ok
6YEK_A	Q9Y6K9	Inhibitor of kappa light polypeptide gene	X-ray	3.20	2020-03-25	—	82.00	0.85	—	—	—	0.12	ok
6M3I_B	P09874	Poly [ADP-ribose] polymerase 1	X-ray	1.98	2020-03-03	0.00	93.41	0.98	0.90	74.03	4.76	0.12	ok
7CKX_A	P63092	Guanine nucleotide-binding protein G(s) su	EM	3.54	2020-07-20	—	91.31	0.87	—	—	—	0.12	ok
7CRH_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.30	2020-08-13	—	89.56	0.87	—	—	—	0.12	ok
7L9P_G	Q9UI95	Mitotic spindle assembly checkpoint protei	EM	3.60	2021-01-04	—	90.38	0.88	—	—	—	0.11	ok
7CKX_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.54	2020-07-20	—	89.56	0.88	—	—	—	0.10	ok
6YTU_A	Q7LC44	Activity-regulated cytoskeleton-associated	X-ray	0.95	2020-04-24	—	65.06	0.85	—	—	—	0.10	ok
7LJD_R	P21728	D(1A) dopamine receptor	EM	3.20	2021-01-28	—	72.44	0.89	—	—	—	0.08	ok
7L9P_A	Q15645	Pachytene checkpoint protein 2 homolog	EM	3.60	2021-01-04	—	86.69	0.91	—	—	—	0.08	ok
7CKW_R	P21728	D(1A) dopamine receptor	EM	3.22	2020-07-20	—	72.44	0.89	—	—	—	0.08	ok
7CKZ_R	P21728	D(1A) dopamine receptor	EM	3.10	2020-07-20	—	72.44	0.89	—	—	—	0.08	ok
7CRH_R	P21728	D(1A) dopamine receptor	EM	3.30	2020-08-13	—	72.44	0.89	—	—	—	0.08	ok
7CKY_R	P21728	D(1A) dopamine receptor	EM	3.20	2020-07-20	—	72.44	0.89	—	—	—	0.08	ok
7CKX_R	P21728	D(1A) dopamine receptor	EM	3.54	2020-07-20	—	72.44	0.90	—	—	—	0.08	ok
7LJC_R	P21728	D(1A) dopamine receptor	EM	3.00	2021-01-28	—	72.44	0.90	—	—	—	0.07	ok
7AVY_A	Q12866	Tyrosine-protein kinase Mer	X-ray	2.31	2020-11-06	—	72.25	0.90	—	—	—	0.07	ok
6ZUJ_AAA	Q9GZT4	Serine racemase	X-ray	1.80	2020-07-23	—	93.94	0.93	—	—	—	0.07	ok
7NBC_AAA	Q9GZT4	Serine racemase	X-ray	1.71	2021-01-26	—	93.94	0.93	—	—	—	0.07	ok
7NBF_AAA	Q9GZT4	Serine racemase	X-ray	1.60	2021-01-26	—	93.94	0.93	—	—	—	0.07	ok
7NBH_AAA	Q9GZT4	Serine racemase	X-ray	1.77	2021-01-26	—	93.94	0.93	—	—	—	0.07	ok
7NBG_AAA	Q9GZT4	Serine racemase	X-ray	1.53	2021-01-26	—	93.94	0.93	—	—	—	0.06	ok
7LUP_F	P50991	T-complex protein 1 subunit delta	EM	6.20	2021-02-22	—	89.69	0.93	—	—	—	0.06	ok
7NBD_AAA	Q9GZT4	Serine racemase	X-ray	1.86	2021-01-26	—	93.94	0.93	—	—	—	0.06	ok
7LUM_F	P50991	T-complex protein 1 subunit delta	EM	4.50	2021-02-22	—	89.69	0.93	—	—	—	0.06	ok
7BLO_A	Q96QK1	Vacuolar protein sorting-associated protei	EM	9.50	2021-01-18	—	91.25	0.93	—	—	—	0.06	ok
7LLA_A	P53396	ATP-citrate synthase	EM	2.97	2021-02-03	—	92.25	0.94	—	—	—	0.06	ok
7AW4_A	Q12866	Tyrosine-protein kinase Mer	X-ray	1.98	2020-11-06	—	72.25	0.92	—	—	—	0.06	ok
6Z1X_A	P51659	Peroxisomal multifunctional enzyme type 2	X-ray	2.09	2020-05-14	—	89.00	0.94	—	—	—	0.06	ok
6Z1W_A	P51659	Peroxisomal multifunctional enzyme type 2	X-ray	2.48	2020-05-14	—	89.00	0.94	—	—	—	0.05	ok
7AVX_A	Q12866	Tyrosine-protein kinase Mer	X-ray	2.44	2020-11-06	—	72.25	0.93	—	—	—	0.05	ok
7AW2_A	Q12866	Tyrosine-protein kinase Mer	X-ray	2.10	2020-11-06	—	72.25	0.93	—	—	—	0.05	ok
7AW3_A	Q12866	Tyrosine-protein kinase Mer	X-ray	1.99	2020-11-06	—	72.25	0.93	—	—	—	0.05	ok
6WTG_D	P0CG48	Ubiquitin	X-ray	2.63	2020-05-02	—	88.62	0.95	—	—	—	0.05	ok
7AW0_A	Q12866	Tyrosine-protein kinase Mer	X-ray	1.89	2020-11-06	—	72.25	0.94	—	—	—	0.05	ok
7AW1_A	Q12866	Tyrosine-protein kinase Mer	X-ray	1.98	2020-11-06	—	72.25	0.94	—	—	—	0.04	ok
6LER_C	P04908	Histone H2A type 1-B/E	X-ray	3.00	2019-11-26	0.00	97.22	0.96	0.99	95.00	0.89	0.04	ok
7LUP_D	P48643	T-complex protein 1 subunit epsilon	EM	6.20	2021-02-22	—	89.38	0.95	—	—	—	0.04	ok
7AVZ_A	Q12866	Tyrosine-protein kinase Mer	X-ray	2.04	2020-11-06	—	72.25	0.94	—	—	—	0.04	ok
7LUM_D	P48643	T-complex protein 1 subunit epsilon	EM	4.50	2021-02-22	—	89.38	0.95	—	—	—	0.04	ok
7BE6_A	Q08345	Epithelial discoidin domain-containing rec	X-ray	1.87	2020-12-22	—	76.19	0.95	—	—	—	0.04	ok
6WW9_X	Q6ZNX1	Shieldin complex subunit 3	X-ray	2.70	2020-05-08	100.00 novel	90.89	0.63	0.96	97.83	0.68	0.04	ok
7LUP_H	P49368	T-complex protein 1 subunit gamma	EM	6.20	2021-02-22	—	89.06	0.96	—	—	—	0.03	ok
7KHD_C	Q9Y5U5	Tumor necrosis factor receptor superfamily	X-ray	2.96	2020-10-21	—	74.38	0.95	—	—	—	0.03	ok
7LUM_H	P49368	T-complex protein 1 subunit gamma	EM	4.50	2021-02-22	—	89.06	0.96	—	—	—	0.03	ok
7KSJ_A	P53779	Mitogen-activated protein kinase 10	X-ray	2.06	2020-11-23	—	79.31	0.96	—	—	—	0.03	ok
7KHD_A	Q9UNG2	Tumor necrosis factor ligand superfamily m	X-ray	2.96	2020-10-21	—	86.75	0.96	—	—	—	0.03	ok
7KSI_A	P53779	Mitogen-activated protein kinase 10	X-ray	1.73	2020-11-23	—	79.31	0.96	—	—	—	0.03	ok
7BBO_AAA	Q8WWQ0	PH-interacting protein	X-ray	1.32	2020-12-18	—	66.06	0.95	—	—	—	0.03	ok
7LUP_C	Q99832	T-complex protein 1 subunit eta	EM	6.20	2021-02-22	—	88.88	0.96	—	—	—	0.03	ok
7LKP_A	P78363	Retinal-specific phospholipid-transporting	EM	3.27	2021-02-02	—	75.69	0.96	—	—	—	0.03	ok
7DSB_C	P58546	Myotrophin	X-ray	2.44	2020-12-30	—	88.25	0.96	—	—	—	0.03	ok
7KSK_A	P53779	Mitogen-activated protein kinase 10	X-ray	1.84	2020-11-23	—	79.31	0.96	—	—	—	0.03	ok
7C3G_A	Q04771	Activin receptor type-1	X-ray	1.80	2020-05-12	—	83.12	0.96	—	—	—	0.03	ok
7LUM_C	Q99832	T-complex protein 1 subunit eta	EM	4.50	2021-02-22	—	88.88	0.97	—	—	—	0.03	ok
7LUP_B	P50990	T-complex protein 1 subunit theta	EM	6.20	2021-02-22	—	87.69	0.97	—	—	—	0.03	ok
7DSA_C	P58546	Myotrophin	X-ray	2.80	2020-12-30	—	88.25	0.97	—	—	—	0.03	ok
6LER_B	P62805	Histone H4	X-ray	3.00	2019-11-26	0.00	95.95	0.97	0.97	98.42	0.96	0.03	ok
7LUM_B	P50990	T-complex protein 1 subunit theta	EM	4.50	2021-02-22	—	87.69	0.97	—	—	—	0.03	ok
7LL9_A	P15692	Isoform L-VEGF189 of Vascular endothelial	X-ray	2.90	2021-02-03	—	63.91	0.96	—	—	—	0.03	ok
6M3I_A	Q9NWY4	Histone PARylation factor 1	X-ray	1.98	2020-03-03	100.00 novel	95.71	0.99	0.98	97.71	0.85	0.03	ok
7BCM_A	Q08345	Epithelial discoidin domain-containing rec	X-ray	2.30	2020-12-20	—	76.19	0.97	—	—	—	0.03	ok
7BLO_F	O75436	Vacuolar protein sorting-associated protei	EM	9.50	2021-01-18	—	87.69	0.97	—	—	—	0.03	ok
7DHZ_A	P04637	Cellular tumor antigen p53	X-ray	1.74	2020-11-18	—	75.06	0.97	—	—	—	0.03	ok
6VXU_A	Q99986	Serine/threonine-protein kinase VRK1	X-ray	2.00	2020-02-24	—	85.00	0.97	—	—	—	0.02	ok
7CKZ_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.10	2020-07-20	—	97.06	0.98	—	—	—	0.02	ok
6WW9_A	Q9UI95	Mitotic spindle assembly checkpoint protei	X-ray	2.70	2020-05-08	—	90.38	0.98	—	—	—	0.02	ok
6XAR_A	P22681	E3 ubiquitin-protein ligase CBL	X-ray	2.50	2020-06-04	—	62.84	0.97	—	—	—	0.02	ok
6WWA_A	Q9UI95	Mitotic spindle assembly checkpoint protei	X-ray	3.80	2020-05-08	—	90.38	0.98	—	—	—	0.02	ok
6LER_D	P06899	Histone H2B type 1-J	X-ray	3.00	2019-11-26	0.00	95.81	0.98	0.98	98.44	0.49	0.02	ok
7CKY_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.20	2020-07-20	—	97.06	0.98	—	—	—	0.02	ok
6M3G_A	Q9NWY4	Histone PARylation factor 1	X-ray	1.57	2020-03-03	100.00 novel	96.67	1.00	0.99	99.26	0.41	0.02	ok
6LER_A	P68431	Histone H3.1	X-ray	3.00	2019-11-26	0.00	95.94	0.98	0.99	98.72	0.61	0.02	ok
7LUP_G	P17987	T-complex protein 1 subunit alpha	EM	6.20	2021-02-22	—	89.00	0.98	—	—	—	0.02	ok
7LUP_E	P78371	T-complex protein 1 subunit beta	EM	6.20	2021-02-22	—	89.81	0.98	—	—	—	0.02	ok
7CKW_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.22	2020-07-20	—	97.06	0.98	—	—	—	0.02	ok
7LUM_G	P17987	T-complex protein 1 subunit alpha	EM	4.50	2021-02-22	—	89.00	0.98	—	—	—	0.02	ok
7B7R_A	Q02750	Dual specificity mitogen-activated protein	X-ray	1.70	2020-12-11	—	83.25	0.98	—	—	—	0.02	ok
7LUM_E	P78371	T-complex protein 1 subunit beta	EM	4.50	2021-02-22	—	89.81	0.98	—	—	—	0.02	ok
6M2B_A	Q02127	Dihydroorotate dehydrogenase (quinone), mi	X-ray	1.76	2020-02-27	0.00	97.72	1.00	0.99	99.32	0.66	0.02	ok
7CKX_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.54	2020-07-20	—	97.06	0.98	—	—	—	0.02	ok
7B3M_A	Q02750	Dual specificity mitogen-activated protein	X-ray	2.30	2020-12-01	—	83.25	0.98	—	—	—	0.02	ok
7LUP_A	P40227	T-complex protein 1 subunit zeta	EM	6.20	2021-02-22	—	89.88	0.98	—	—	—	0.02	ok
7B94_A	Q02750	Dual specificity mitogen-activated protein	X-ray	2.00	2020-12-14	—	83.25	0.98	—	—	—	0.02	ok
7B9L_A	Q02750	Dual specificity mitogen-activated protein	X-ray	1.70	2020-12-14	—	83.25	0.98	—	—	—	0.01	ok
7LUM_A	P40227	T-complex protein 1 subunit zeta	EM	4.50	2021-02-22	—	89.88	0.99	—	—	—	0.01	ok
7BBP_AAA	Q8WWQ0	PH-interacting protein	X-ray	1.99	2020-12-18	—	66.06	0.98	—	—	—	0.01	ok
7CRH_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.30	2020-08-13	—	97.06	0.99	—	—	—	0.01	ok
6VZO_A	P37231	Peroxisome proliferator-activated receptor	X-ray	2.27	2020-02-28	—	76.12	0.99	—	—	—	0.01	ok
7AQ1_A	Q16820	Meprin B subunit beta	X-ray	2.41	2020-10-20	—	89.81	0.99	—	—	—	0.01	ok
7BL1_DDD	P20339	Ras-related protein Rab-5A	EM	9.80	2021-01-17	—	84.88	0.99	—	—	—	0.01	ok
7NCF_A	Q9H2X6	Homeodomain-interacting protein kinase 2	X-ray	2.72	2021-01-28	—	52.41	0.98	—	—	—	0.01	ok
6VZL_A	P37231	Peroxisome proliferator-activated receptor	X-ray	2.07	2020-02-28	—	76.12	0.99	—	—	—	0.01	ok
6VZN_A	P37231	Peroxisome proliferator-activated receptor	X-ray	2.30	2020-02-28	—	76.12	0.99	—	—	—	0.01	ok
7DHY_A	P04637	Cellular tumor antigen p53	X-ray	2.15	2020-11-18	—	75.06	0.99	—	—	—	0.01	ok
7JQG_A	P37231	Peroxisome proliferator-activated receptor	X-ray	2.15	2020-08-10	—	76.12	0.99	—	—	—	0.01	ok
6WOA_A	O95989	Diphosphoinositol polyphosphate phosphohyd	X-ray	1.50	2020-04-24	—	86.75	0.99	—	—	—	0.01	ok
6WOH_A	O95989	Diphosphoinositol polyphosphate phosphohyd	X-ray	1.70	2020-04-24	—	86.75	0.99	—	—	—	0.01	ok
6VZM_A	P37231	Peroxisome proliferator-activated receptor	X-ray	2.40	2020-02-28	—	76.12	0.99	—	—	—	0.01	ok
6ZSP_AAA	Q9GZT4	Serine racemase	X-ray	1.60	2020-07-16	—	93.94	0.99	—	—	—	0.01	ok
6WOG_A	O95989	Diphosphoinositol polyphosphate phosphohyd	X-ray	1.50	2020-04-24	—	86.75	0.99	—	—	—	0.01	ok
6WO9_A	O95989	Diphosphoinositol polyphosphate phosphohyd	X-ray	2.00	2020-04-24	—	86.75	0.99	—	—	—	0.00	ok
6WO8_A	O95989	Diphosphoinositol polyphosphate phosphohyd	X-ray	1.70	2020-04-24	—	86.75	0.99	—	—	—	0.00	ok
7KWO_A	P00451	Coagulation factor FVIII-Fc-XTEN	EM	2.90	2020-12-01	—	60.75	0.99	—	—	—	0.00	ok
6WOB_A	O95989	Diphosphoinositol polyphosphate phosphohyd	X-ray	1.45	2020-04-24	—	86.75	0.99	—	—	—	0.00	ok
6WOI_A	O95989	Diphosphoinositol polyphosphate phosphohyd	X-ray	1.50	2020-04-24	—	86.75	0.99	—	—	—	0.00	ok
6WOF_A	O95989	Diphosphoinositol polyphosphate phosphohyd	X-ray	1.60	2020-04-24	—	86.75	0.99	—	—	—	0.00	ok
6WO7_A	O95989	Diphosphoinositol polyphosphate phosphohyd	X-ray	1.40	2020-04-24	—	86.75	0.99	—	—	—	0.00	ok
6VBA_A	P13051	Uracil-DNA glycosylase	X-ray	1.80	2019-12-18	—	85.31	0.99	—	—	—	0.00	ok
6WOC_A	O95989	Diphosphoinositol polyphosphate phosphohyd	X-ray	1.35	2020-04-24	—	86.75	1.00	—	—	—	0.00	ok
6WOE_A	O95989	Diphosphoinositol polyphosphate phosphohyd	X-ray	1.40	2020-04-24	—	86.75	1.00	—	—	—	0.00	ok
6WOD_A	O95989	Diphosphoinositol polyphosphate phosphohyd	X-ray	1.35	2020-04-24	—	86.75	1.00	—	—	—	0.00	ok
7BJ1_A	Q9H7B4	Histone-lysine N-methyltransferase SMYD3	X-ray	1.61	2021-01-13	—	97.31	1.00	—	—	—	0.00	ok

Click a column header to sort. FRAUD = confidence-weighted error; a structure is flagged confidently wrong when mean pLDDT > 70 yet TM-score < 0.5.