Release week 2020-12-09

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179

structures analysed (39 full · 21.8%)

52.8%

confidently wrong

31.7%

novel sequences

00.0%

novel & wrong

0.964

median TM-score

⭐ This week's notable releases

3 novel sequences, 5 confidently wrong. Highlight: Amyloid-beta 17-36 peptide.

PDB	Protein	Flags	Why it matters
7JXN_A ↗	Amyloid-beta 17-36 peptide	novel · 100% disease	Genuinely unseen sequence (0% identity to anything AlphaFold trained on). Disease-linked.
7JXO_A ↗	Amyloid-beta 17-36 peptide	novel · 100% disease	Genuinely unseen sequence (0% identity to anything AlphaFold trained on). Disease-linked.
7JPU_A ↗	Lymphocyte antigen 75	confidently wrong	A close pre-cutoff homolog existed (40% identity to 5AO5_1) yet AlphaFold confidently missed the fold.
7ASY_A ↗	Tumor necrosis factor	confidently wrong disease	A close pre-cutoff homolog existed yet AlphaFold confidently missed the fold. Disease-linked.
7ABH_F ↗	Splicing factor 3A subunit 2	novel · 72%	Genuinely unseen sequence (28% identity to anything AlphaFold trained on).
7AT7_A ↗	Tumor necrosis factor	confidently wrong disease	A close pre-cutoff homolog existed yet AlphaFold confidently missed the fold. Disease-linked.

see all 179 structures ↓

Zoomed into the red "confidently wrong" box above (pLDDT ≥ 70, TM < 0.5) — the structures AlphaFold got confidently wrong.

The worst offenders ranked, one row per protein (AlphaFold has one model per sequence, so repeat depositions are collapsed — “×N” marks how many structures of that protein exist; the worst is shown). Each row joins what AlphaFold claimed (blue, pLDDT/100) to what the experiment showed (red, TM-score) — the longer the bar, the bigger the miss. Hover a dot to preview its Cα-deviation ribbon; click to open the full entry.

How to read this

Every point is one experimental protein structure. The horizontal axis is AlphaFold's own confidence in its prediction (mean pLDDT, 0–100). The vertical axis is how well that blind prediction actually matches the experiment (TM-score, 0–1; above 0.5 means the same fold, above 0.9 near-identical). Marker size grows with the FRAUD score (confidence-weighted error).

Cutoff: the shaded red box is the "confidently wrong" zone — AlphaFold was confident (mean pLDDT above 70) yet the fold is wrong (TM-score below 0.5). A predictor that had truly solved folding would leave that box empty.

Take-home: 5 of 179 structures (2.8%) are confidently wrong; median TM-score is 0.964.

Read moreShow less — how each metric is calculated

TM-score: how similar the two 3D shapes are overall, 0–1 (a random pair scores ~0.17, an identical fold ~1). Length-normalised so large and small proteins compare fairly. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) — dᵢ is the gap between the i-th aligned Cα atoms after best-fit superposition, and d₀ = 1.24(L−15)^⅓ − 1.8 sets the distance scale for length L. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264; computed with TM-align, doi:10.1093/nar/gki524.

pLDDT: AlphaFold's own confidence in each residue, 0–100 (higher = surer). It is the model predicting its own accuracy before ever seeing the experiment. We plot the per-structure mean. pLDDT = (1/N) Σᵢ pLDDTᵢ, where pLDDTᵢ is the network's confidence output for residue i.

FRAUD score: the headline number — how wrong the prediction was, weighted by how confident AlphaFold was, so a big error it was sure about counts most. FRAUD = (1/N) Σᵢ (pLDDTᵢ/100) · min(Δᵢ,15)/15, where Δᵢ is residue i's Cα distance from the experiment (Å) after superposition, capped at 15 Å. Runs 0 (perfect) to 1.

Novelty: how little AlphaFold had to go on — 100 minus the highest sequence identity between this protein and any structure released before the 2018-04-30 training cutoff. High = genuinely unseen (100% = nothing similar was ever in the training set). novelty = 100 − maxₚ identity(s, p) over pre-cutoff PDB chains p, with identity = 100 × (matching aligned residues)/(alignment length), from an MMseqs2 search.

Homology: the point colour. High novelty (above 70%) flags the sequence as novel (amber) — AlphaFold had no close template; otherwise a pre-cutoff homolog existed (blue) it could have learned the fold from. novel ⇔ novelty > 70%.

What the metrics mean

TM-score (0–1): overall fold match — above 0.5 is the same fold, above 0.9 near-identical. Cα-RMSD (Å): average backbone distance after best-fit superposition — lower is better (under 2 Å is excellent). lDDT (0–1): local accuracy measured without superposition — above 0.8 is good. Each bar counts how many structures fall in that range.

Take-home: median TM-score 0.964 — most predictions match the experimental fold well, with a long tail that do not.

Read moreShow less — how each metric is calculated

TM-score: overall shape match, 0–1 (above 0.5 = same fold, above 0.9 near-identical), length-normalised. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) with dᵢ the aligned-Cα gap after superposition and d₀ = 1.24(L−15)^⅓ − 1.8. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264.

Cα-RMSD: the average straight-line distance between matching backbone Cα atoms once the two structures are best-fit superposed (Å; lower is better, under ~2 Å excellent). RMSD = √( (1/N) Σᵢ |Pᵢ − (R·Qᵢ + t)|² ), with Pᵢ/Qᵢ the experimental/model Cα coordinates and R,t the rotation and translation from Kabsch superposition.

lDDT: local accuracy with no superposition — the fraction of short-range inter-residue distances the model reproduces, so it is not fooled by a single wrongly-placed domain. lDDT = (1/N) Σᵢ ¼ Σ_t 1[ |d_exp − d_model| < t ] over thresholds t ∈ {0.5, 1, 2, 4} Å and all residue pairs within 15 Å.

Trend over time

The blue line is the mean TM-score of the structures by their deposit month; the red bars count how many were confidently wrong. Binning by deposit date (rather than by when we processed them) gives an even timeline, tracking whether AlphaFold's accuracy on newly-deposited structures is holding steady, improving, or slipping as the PDB keeps growing. Months with fewer than 5 structures are omitted so each point is a meaningful average. A dashed trend line is drawn only if the change over time is statistically significant.

Read moreShow less — how each metric is calculated

Mean TM-score: the month's average shape-match score. TM̄ = (1/M) Σ TM over the M structures deposited that month.

Trend line: a monotonic-trend test over the monthly means — Mann-Kendall (Kendall's τ) for significance, with a robust Theil-Sen slope for the line. Rank-based, so it tolerates the skewed TM distribution and noisy low-count months. Shown only when p < 0.05; otherwise a note reports that no significant trend was found.

Confidently wrong: the count that were both confident and wrong. count( mean pLDDT > 70 AND TM < 0.5 ).

Matched structures

PDB	UniProt	Protein	Method	Å	Deposited	Novelty %	pLDDT	TM	lDDT	GDT_TS	RMSD	FRAUD	Flag
7ABF_v	Q13573	SNW domain-containing protein 1	EM	3.90	2020-09-07	0.00	93.87	0.56	0.82	0.00	22.33	0.94	ok
7JPU_A	O60449	Lymphocyte antigen 75	EM	5.00	2020-08-09	60.00	80.35	0.41	0.67	1.47	24.55	0.73	wrong
7JTQ_A	P00751	Complement factor B	X-ray	3.50	2020-08-18	0.20	90.00	0.60	0.86	7.50	14.50	0.68	ok
7JTN_A	P00751	Complement factor B	X-ray	3.10	2020-08-18	0.20	90.02	0.60	0.86	7.48	14.45	0.68	ok
7JPT_A	O60449	Lymphocyte antigen 75	EM	3.20	2020-08-09	60.00	78.40	0.59	0.71	4.20	28.00	0.64	ok
7ASY_A	P01375	Tumor necrosis factor	NMR	—	2020-10-28	—	84.56	0.43	—	—	—	0.48	wrong
7AT7_A	P01375	Tumor necrosis factor	NMR	—	2020-10-29	—	84.56	0.49	—	—	—	0.43	wrong
7ATB_A	P01375	Tumor necrosis factor	NMR	—	2020-10-29	—	84.56	0.55	—	—	—	0.38	ok
7ABH_F	Q15428	Splicing factor 3A subunit 2	EM	4.50	2020-09-07	71.90 novel	87.60	0.61	0.71	26.67	6.96	0.37	ok
7AAV_v	Q13573	SNW domain-containing protein 1	EM	4.20	2020-09-04	0.00	89.48	0.67	0.84	30.34	6.53	0.33	ok
7JXN_A	P05067	Amyloid-beta 17-36 peptide	X-ray	2.00	2020-08-27	100.00 novel	47.71	0.31	0.36	16.67	9.94	0.29	ok
7JXO_A	P05067	Amyloid-beta 17-36 peptide	X-ray	2.81	2020-08-27	100.00 novel	47.71	0.30	0.37	17.86	9.73	0.28	ok
7D43_K	P05198	Eukaryotic translation initiation factor 2	EM	4.30	2020-09-22	1.40	80.86	0.69	0.68	36.92	5.81	0.26	ok
6VEC_a	P13796	LCP1	EM	3.90	2019-12-31	—	89.62	0.72	—	—	—	0.25	ok
7ABF_A	Q6P2Q9	Pre-mRNA-processing-splicing factor 8	EM	3.90	2020-09-07	—	84.94	0.71	—	—	—	0.25	ok
7AAV_A	Q6P2Q9	Pre-mRNA-processing-splicing factor 8	EM	4.20	2020-09-04	—	84.94	0.72	—	—	—	0.24	ok
7ABH_z	Q9Y3B4	Splicing factor 3B subunit 6	EM	4.50	2020-09-07	—	90.12	0.74	—	—	—	0.23	ok
7ABH_4	Q12874	Splicing factor 3A subunit 3	EM	4.50	2020-09-07	—	86.25	0.75	—	—	—	0.22	ok
7AAV_K	P55081	Microfibrillar-associated protein 1	EM	4.20	2020-09-04	0.00	83.72	0.63	0.77	43.90	4.08	0.21	ok
7ABF_K	P55081	Microfibrillar-associated protein 1	EM	3.90	2020-09-07	0.00	83.72	0.63	0.76	44.72	4.08	0.21	ok
7ABF_N	Q96NC0	Zinc finger matrin-type protein 2	EM	3.90	2020-09-07	—	71.75	0.72	—	—	—	0.20	ok
7ABH_x	Q9BWJ5	Splicing factor 3B subunit 5	EM	4.50	2020-09-07	—	91.62	0.78	—	—	—	0.20	ok
7D43_P	P41091	Eukaryotic translation initiation factor 2	EM	4.30	2020-09-22	—	85.12	0.78	—	—	—	0.18	ok
6PJX_A	P34947	G protein-coupled receptor kinase 5	X-ray	1.96	2019-06-28	0.00	94.23	0.89	0.95	57.93	3.04	0.17	ok
7ABH_T	Q13435	Splicing factor 3B subunit 2	EM	4.50	2020-09-07	—	65.69	0.76	—	—	—	0.16	ok
7ABF_A4	O14776	Transcription elongation regulator 1	EM	3.90	2020-09-07	—	67.88	0.78	—	—	—	0.15	ok
7ABF_Q	P41223	Protein BUD31 homolog	EM	3.90	2020-09-07	—	90.75	0.84	—	—	—	0.15	ok
6YHP_A	P05067	Amyloid-beta precursor protein V44M mutant	NMR	—	2020-03-30	3.40	72.92	0.56	0.88	54.17	3.31	0.14	ok
7D43_M	P20042	Eukaryotic translation initiation factor 2	EM	4.30	2020-09-22	56.00	87.36	0.45	0.79	57.81	2.77	0.14	wrong
7ABF_R	Q9P013	Spliceosome-associated protein CWC15 homol	EM	3.90	2020-09-07	—	74.88	0.82	—	—	—	0.14	ok
7ABH_0	Q8TAD8	Smad nuclear-interacting protein 1	EM	4.50	2020-09-07	—	66.06	0.80	—	—	—	0.14	ok
7ABF_X	Q9Y2W2	WW domain-binding protein 11	EM	3.90	2020-09-07	—	62.59	0.80	—	—	—	0.13	ok
6YHF_A	P05067	Amyloid-beta precursor protein	NMR	—	2020-03-29	0.00	72.92	0.51	0.80	55.83	3.03	0.13	ok
6YHI_A	P05067	Amyloid-beta precursor protein G38L mutant	NMR	—	2020-03-30	3.40	72.92	0.54	0.82	56.67	3.10	0.12	ok
7CCS_B	Q9UPY5	Consensus mutated Anionic Amino Acid Trans	EM	6.20	2020-06-17	—	85.56	0.87	—	—	—	0.11	ok
7D45_K	P05198	Eukaryotic translation initiation factor 2	EM	3.80	2020-09-22	—	77.81	0.86	—	—	—	0.11	ok
7AAV_R	Q9P013	Spliceosome-associated protein CWC15 homol	EM	4.20	2020-09-04	0.00	85.75	0.68	0.80	73.86	2.54	0.11	ok
7AAV_N	Q96NC0	Zinc finger matrin-type protein 2	EM	4.20	2020-09-04	0.00	78.28	0.69	0.78	66.96	2.34	0.10	ok
7B44_A	P08581	Hepatocyte growth factor receptor	X-ray	1.76	2020-12-02	—	79.25	0.87	—	—	—	0.10	ok
7B3Q_A	P08581	Hepatocyte growth factor receptor	X-ray	1.75	2020-12-01	—	79.25	0.88	—	—	—	0.10	ok
7B42_A	P08581	Hepatocyte growth factor receptor	X-ray	1.80	2020-12-02	—	79.25	0.88	—	—	—	0.09	ok
7B40_A	P08581	Hepatocyte growth factor receptor	X-ray	1.76	2020-12-01	—	79.25	0.88	—	—	—	0.09	ok
7AFV_A	P61769	Beta-2-microglobulin	X-ray	2.40	2020-09-20	—	94.06	0.90	—	—	—	0.09	ok
7ABH_u	O75533	Splicing factor 3B subunit 1	EM	4.50	2020-09-07	—	74.81	0.88	—	—	—	0.09	ok
7B41_A	P08581	Hepatocyte growth factor receptor	X-ray	1.97	2020-12-02	—	79.25	0.88	—	—	—	0.09	ok
7B3Z_A	P08581	Hepatocyte growth factor receptor	X-ray	1.80	2020-12-01	—	79.25	0.89	—	—	—	0.09	ok
6YHO_A	P05067	Amyloid-beta precursor protein G38P mutant	NMR	—	2020-03-30	3.40	72.92	0.45	0.85	68.33	2.05	0.09	wrong
7B43_A	P08581	Hepatocyte growth factor receptor	X-ray	1.87	2020-12-02	—	79.25	0.89	—	—	—	0.09	ok
7AAV_8	O60508	Pre-mRNA-processing factor 17	EM	4.20	2020-09-04	0.00	93.89	0.51	0.90	77.78	1.49	0.09	ok
7JL3_A	O95786	Antiviral innate immune response receptor	EM	4.20	2020-07-29	—	85.19	0.90	—	—	—	0.09	ok
7ABF_q	Q9BZL1	Ubiquitin-like protein 5	EM	3.90	2020-09-07	—	91.69	0.91	—	—	—	0.09	ok
7ABH_7	O60870	DNA/RNA-binding protein KIN17	EM	4.50	2020-09-07	—	77.75	0.89	—	—	—	0.09	ok
7D44_K	P05198	Eukaryotic translation initiation factor 2	EM	4.00	2020-09-22	—	77.81	0.89	—	—	—	0.08	ok
7JL1_A	O95786	Antiviral innate immune response receptor	EM	3.90	2020-07-29	—	85.19	0.90	—	—	—	0.08	ok
7ABH_w	Q15427	Splicing factor 3B subunit 4	EM	4.50	2020-09-07	—	73.19	0.89	—	—	—	0.08	ok
7AAV_L	Q99459	Cell division cycle 5-like protein	EM	4.20	2020-09-04	—	74.31	0.89	—	—	—	0.08	ok
7AAV_q	Q9BZL1	Ubiquitin-like protein 5	EM	4.20	2020-09-04	—	91.69	0.91	—	—	—	0.08	ok
7B3V_A	P08581	Hepatocyte growth factor receptor	X-ray	1.93	2020-12-01	—	79.25	0.90	—	—	—	0.08	ok
7K81_G	P43629	KIR3DL1	X-ray	2.00	2020-09-24	—	75.62	0.90	—	—	—	0.08	ok
7ABH_L	Q99459	Cell division cycle 5-like protein	EM	4.50	2020-09-07	—	74.31	0.90	—	—	—	0.08	ok
7AAV_Q	P41223	Protein BUD31 homolog	EM	4.20	2020-09-04	—	90.75	0.92	—	—	—	0.07	ok
7B3T_A	P08581	Hepatocyte growth factor receptor	X-ray	2.23	2020-12-01	—	79.25	0.91	—	—	—	0.07	ok
6KZB_A	P21980	Protein-glutamine gamma-glutamyltransferas	X-ray	3.55	2019-09-23	0.00	93.11	0.98	0.88	85.28	1.53	0.07	ok
6YHX_A	P05067	Amyloid-beta precursor protein I45T mutant	NMR	—	2020-03-31	3.40	72.92	0.67	0.89	76.67	1.83	0.07	ok
7ABF_G	O43660	Pleiotropic regulator 1	EM	3.90	2020-09-07	—	77.38	0.91	—	—	—	0.07	ok
7ABH_1	Q9Y388	RNA-binding motif protein, X-linked 2	EM	4.50	2020-09-07	—	63.66	0.90	—	—	—	0.07	ok
7D43_E	Q9NR50	Translation initiation factor eIF-2B subun	EM	4.30	2020-09-22	—	72.56	0.91	—	—	—	0.07	ok
7ABH_y	Q7RTV0	PHD finger-like domain-containing protein	EM	4.50	2020-09-07	—	89.88	0.93	—	—	—	0.06	ok
7KSL_A	P36776	Lon protease homolog, mitochondrial	EM	3.50	2020-11-23	—	76.69	0.92	—	—	—	0.06	ok
6UGH_A	O14744	Protein arginine N-methyltransferase 5	EM	3.40	2019-09-26	0.00	94.99	0.98	0.93	89.86	1.14	0.06	ok
7D46_E	Q9NR50	Translation initiation factor eIF-2B subun	EM	4.00	2020-09-22	—	72.56	0.92	—	—	—	0.06	ok
7D44_E	Q9NR50	Translation initiation factor eIF-2B subun	EM	4.00	2020-09-22	—	72.56	0.92	—	—	—	0.06	ok
7CCS_A	P08195	4F2 cell-surface antigen heavy chain	EM	6.20	2020-06-17	—	78.69	0.94	—	—	—	0.05	ok
7D45_E	Q9NR50	Translation initiation factor eIF-2B subun	EM	3.80	2020-09-22	—	72.56	0.93	—	—	—	0.05	ok
7AT8_A	Q15910	Isoform 2 of Histone-lysine N-methyltransf	EM	4.40	2020-10-29	—	76.25	0.93	—	—	—	0.05	ok
7D3E_A	Q9NRD9	Dual oxidase 1	EM	2.80	2020-09-19	—	85.62	0.94	—	—	—	0.05	ok
6XY2_A	P16410	Cytotoxic T-lymphocyte protein 4	X-ray	3.05	2020-01-29	—	80.12	0.94	—	—	—	0.05	ok
6V6M_A	P61586	Transforming protein RhoA	X-ray	1.39	2019-12-05	—	93.56	0.95	—	—	—	0.04	ok
7KP4_A	O14493	Claudin-4	X-ray	3.37	2020-11-10	—	84.56	0.95	—	—	—	0.04	ok
7KNB_D	Q9BYF1	Angiotensin-converting enzyme 2	EM	3.93	2020-11-04	—	90.69	0.95	—	—	—	0.04	ok
7AT8_C	Q15022	Polycomb protein SUZ12	EM	4.40	2020-10-29	—	71.00	0.94	—	—	—	0.04	ok
7AAV_I	Q8NAV1	Pre-mRNA-splicing factor 38A	EM	4.20	2020-09-04	—	71.31	0.94	—	—	—	0.04	ok
7K80_G	P43629	Killer cell immunoglobulin-like receptor 3	X-ray	2.40	2020-09-24	—	75.62	0.94	—	—	—	0.04	ok
7B3W_A	P08581	Hepatocyte growth factor receptor	X-ray	2.02	2020-12-01	—	79.25	0.95	—	—	—	0.04	ok
7ABF_I	Q8NAV1	Pre-mRNA-splicing factor 38A	EM	3.90	2020-09-07	—	71.31	0.94	—	—	—	0.04	ok
7AAV_r	Q15029	116 kDa U5 small nuclear ribonucleoprotein	EM	4.20	2020-09-04	—	89.94	0.96	—	—	—	0.04	ok
7AAV_P	Q9NW64	Pre-mRNA-splicing factor RBM22	EM	4.20	2020-09-04	—	76.12	0.95	—	—	—	0.04	ok
6S6K_A	O60885	Bromodomain-containing protein 4	X-ray	1.40	2019-07-03	0.00	94.30	0.97	0.95	96.26	0.80	0.04	ok
6RWJ_A	O60885	Bromodomain-containing protein 4	X-ray	1.40	2019-06-05	0.00	94.30	0.97	0.95	95.87	0.91	0.04	ok
7ABH_Y	Q8IYB3	Serine/arginine repetitive matrix protein	EM	4.50	2020-09-07	—	51.62	0.93	—	—	—	0.04	ok
6SAH_A	O60885	Bromodomain-containing protein 4	X-ray	1.50	2019-07-16	0.00	94.30	0.97	0.95	96.26	0.79	0.04	ok
6SA2_A	O60885	Bromodomain-containing protein 4	X-ray	1.50	2019-07-16	0.00	94.30	0.97	0.95	96.26	0.78	0.04	ok
7K4C_A	Q9H1D0	Transient receptor potential cation channe	EM	3.78	2020-09-15	—	80.56	0.96	—	—	—	0.04	ok
6LG8_A	O60885	Bromodomain-containing protein 4	X-ray	1.58	2019-12-04	0.00	94.61	0.97	0.96	96.37	0.79	0.04	ok
6S4B_A	O60885	Bromodomain-containing protein 4	X-ray	1.60	2019-06-27	0.00	94.30	0.98	0.96	96.85	0.74	0.03	ok
6LG6_A	O60885	Bromodomain-containing protein 4	X-ray	1.98	2019-12-04	0.00	94.61	0.97	0.95	96.98	0.78	0.03	ok
6LG9_A	O60885	Bromodomain-containing protein 4	X-ray	1.81	2019-12-04	0.00	94.61	0.97	0.95	97.18	0.77	0.03	ok
6LG7_A	O60885	Bromodomain-containing protein 4	X-ray	1.83	2019-12-04	0.00	94.61	0.98	0.96	97.38	0.76	0.03	ok
6LG5_A	O60885	Bromodomain-containing protein 4	X-ray	1.83	2019-12-04	0.00	94.61	0.97	0.96	97.18	0.78	0.03	ok
6LG4_A	O60885	Bromodomain-containing protein 4	X-ray	1.85	2019-12-04	0.00	94.61	0.97	0.96	96.77	0.78	0.03	ok
6UGH_B	Q9BQA1	Methylosome protein 50	EM	3.40	2019-09-26	1.40	95.96	0.99	0.95	98.34	0.64	0.03	ok
6SA3_A	O60885	Bromodomain-containing protein 4	X-ray	1.80	2019-07-16	0.00	96.30	0.98	0.97	98.17	0.83	0.03	ok
7JL4_A	Q6PJ69	Tripartite motif-containing protein 65	X-ray	1.92	2020-07-29	—	84.00	0.96	—	—	—	0.03	ok
7KMZ_D	Q9BYF1	Angiotensin-converting enzyme 2	EM	3.62	2020-11-03	—	90.69	0.96	—	—	—	0.03	ok
6Z80_K	P30047	GTP cyclohydrolase 1 feedback regulatory p	EM	3.00	2020-06-02	—	97.94	0.97	—	—	—	0.03	ok
6SB8_A	O60885	Bromodomain-containing protein 4	X-ray	1.50	2019-07-19	0.00	94.30	0.98	0.96	97.44	0.70	0.03	ok
6UZ4_A	P00747	Plasminogen	NMR	—	2019-11-14	—	82.81	0.96	—	—	—	0.03	ok
7D46_A	Q14232	Translation initiation factor eIF-2B subun	EM	4.00	2020-09-22	—	91.81	0.97	—	—	—	0.03	ok
7JRA_A	P01375	Tumor necrosis factor	X-ray	2.10	2020-08-11	—	84.56	0.97	—	—	—	0.03	ok
6LH4_A	Q9BQ69	ADP-ribose glycohydrolase MACROD1	X-ray	2.00	2019-12-06	0.00	95.93	0.98	0.97	97.77	1.12	0.03	ok
6UZ5_A	P00747	Plasminogen	NMR	—	2019-11-14	—	82.81	0.97	—	—	—	0.03	ok
7JL2_A	Q9BYX4	Interferon-induced helicase C domain-conta	EM	4.30	2020-07-29	—	79.44	0.96	—	—	—	0.03	ok
7D43_C	P49770	Translation initiation factor eIF-2B subun	EM	4.30	2020-09-22	—	86.56	0.97	—	—	—	0.03	ok
7JL3_B	Q8IUD6	E3 ubiquitin-protein ligase RNF135	EM	4.20	2020-07-29	—	76.12	0.96	—	—	—	0.03	ok
7JL0_A	Q9BYX4	Interferon-induced helicase C domain-conta	EM	4.30	2020-07-29	—	79.44	0.97	—	—	—	0.03	ok
7AAV_G	O43660	Pleiotropic regulator 1	EM	4.20	2020-09-04	—	77.38	0.97	—	—	—	0.03	ok
7ACC_A	P30047	GTP cyclohydrolase 1 feedback regulatory p	X-ray	2.04	2020-09-10	—	97.94	0.97	—	—	—	0.03	ok
7K4E_A	Q9H1D0	Transient receptor potential cation channe	EM	4.34	2020-09-15	—	80.56	0.97	—	—	—	0.03	ok
7JL0_B	Q6PJ69	Tripartite motif-containing protein 65	EM	4.30	2020-07-29	—	84.00	0.97	—	—	—	0.03	ok
7AK1_A	Q9UDY8	Mucosa-associated lymphoid tissue lymphoma	X-ray	2.51	2020-09-29	—	79.44	0.97	—	—	—	0.02	ok
7D46_C	P49770	Translation initiation factor eIF-2B subun	EM	4.00	2020-09-22	—	86.56	0.97	—	—	—	0.02	ok
7JL2_B	Q6PJ69	Tripartite motif-containing protein 65	EM	4.30	2020-07-29	—	84.00	0.97	—	—	—	0.02	ok
7D44_C	P49770	Translation initiation factor eIF-2B subun	EM	4.00	2020-09-22	—	86.56	0.97	—	—	—	0.02	ok
7CIO_A	P27986	Phosphatidylinositol 3-kinase regulatory s	X-ray	1.10	2020-07-08	—	83.19	0.97	—	—	—	0.02	ok
7D45_C	P49770	Translation initiation factor eIF-2B subun	EM	3.80	2020-09-22	—	86.56	0.97	—	—	—	0.02	ok
7K4F_A	Q9H1D0	Transient receptor potential cation channe	EM	3.75	2020-09-15	—	80.56	0.97	—	—	—	0.02	ok
6Z89_A	P30793	GTP cyclohydrolase 1	X-ray	2.37	2020-06-02	—	86.50	0.97	—	—	—	0.02	ok
7K4D_A	Q9H1D0	Transient receptor potential cation channe	EM	3.66	2020-09-15	—	80.56	0.97	—	—	—	0.02	ok
6Z85_A	P30793	GTP cyclohydrolase 1	EM	2.90	2020-06-02	—	86.50	0.97	—	—	—	0.02	ok
7K80_B	P61769	Beta-2-microglobulin	X-ray	2.40	2020-09-24	—	94.06	0.98	—	—	—	0.02	ok
7D43_I	Q13144	Translation initiation factor eIF-2B subun	EM	4.30	2020-09-22	—	78.75	0.97	—	—	—	0.02	ok
7D43_G	Q9UI10	Translation initiation factor eIF-2B subun	EM	4.30	2020-09-22	—	76.50	0.97	—	—	—	0.02	ok
7D43_A	Q14232	Translation initiation factor eIF-2B subun	EM	4.30	2020-09-22	—	91.81	0.98	—	—	—	0.02	ok
7D44_A	Q14232	Translation initiation factor eIF-2B subun	EM	4.00	2020-09-22	—	91.81	0.98	—	—	—	0.02	ok
7D44_G	Q9UI10	Translation initiation factor eIF-2B subun	EM	4.00	2020-09-22	—	76.50	0.97	—	—	—	0.02	ok
7AK0_A	Q9UDY8	Mucosa-associated lymphoid tissue lymphoma	X-ray	2.32	2020-09-29	—	79.44	0.97	—	—	—	0.02	ok
7ABF_r	Q15029	116 kDa U5 small nuclear ribonucleoprotein	EM	3.90	2020-09-07	—	89.94	0.98	—	—	—	0.02	ok
6Z87_A	P30793	GTP cyclohydrolase 1	X-ray	2.56	2020-06-02	—	86.50	0.98	—	—	—	0.02	ok
6WMI_A	Q86VK4	Zinc finger protein 410	X-ray	2.75	2020-04-21	—	48.34	0.96	—	—	—	0.02	ok
7D44_I	Q13144	Translation initiation factor eIF-2B subun	EM	4.00	2020-09-22	—	78.75	0.97	—	—	—	0.02	ok
7D45_A	Q14232	Translation initiation factor eIF-2B subun	EM	3.80	2020-09-22	—	91.81	0.98	—	—	—	0.02	ok
7KMS_D	Q9BYF1	Angiotensin-converting enzyme 2	EM	3.64	2020-11-03	—	90.69	0.98	—	—	—	0.02	ok
6W3E_A	O75460	Serine/threonine-protein kinase/endoribonu	X-ray	2.74	2020-03-09	—	72.69	0.97	—	—	—	0.02	ok
7D46_G	Q9UI10	Translation initiation factor eIF-2B subun	EM	4.00	2020-09-22	—	76.50	0.98	—	—	—	0.02	ok
7D45_G	Q9UI10	Translation initiation factor eIF-2B subun	EM	3.80	2020-09-22	—	76.50	0.98	—	—	—	0.02	ok
7K4A_A	Q9H1D0	Transient receptor potential cation channe	EM	3.26	2020-09-15	—	80.56	0.98	—	—	—	0.02	ok
7JL1_B	Q8IUD6	E3 ubiquitin-protein ligase RNF135	EM	3.90	2020-07-29	—	76.12	0.98	—	—	—	0.02	ok
7D46_I	Q13144	Translation initiation factor eIF-2B subun	EM	4.00	2020-09-22	—	78.75	0.98	—	—	—	0.02	ok
6Z85_K	P30047	GTP cyclohydrolase 1 feedback regulatory p	EM	2.90	2020-06-02	—	97.94	0.98	—	—	—	0.02	ok
7D45_I	Q13144	Translation initiation factor eIF-2B subun	EM	3.80	2020-09-22	—	78.75	0.98	—	—	—	0.02	ok
7K81_B	P61769	Beta-2-microglobulin	X-ray	2.00	2020-09-24	—	94.06	0.98	—	—	—	0.02	ok
7JX7_A	P25440	Bromodomain-containing protein 2	X-ray	1.75	2020-08-26	—	64.06	0.97	—	—	—	0.02	ok
6W3A_A	O75460	Serine/threonine-protein kinase/endoribonu	X-ray	2.61	2020-03-09	—	72.69	0.98	—	—	—	0.02	ok
6Z88_A	P30793	GTP cyclohydrolase 1	X-ray	2.69	2020-06-02	—	86.50	0.98	—	—	—	0.02	ok
7K4B_A	Q9H1D0	Transient receptor potential cation channe	EM	3.10	2020-09-15	—	80.56	0.98	—	—	—	0.02	ok
7K81_A	A0A5H2UYS3	MHC class I antigen	X-ray	2.00	2020-09-24	—	85.25	0.98	—	—	—	0.02	ok
7KMB_F	Q9BYF1	Angiotensin-converting enzyme 2	EM	3.39	2020-11-02	—	90.69	0.98	—	—	—	0.01	ok
6V7K_A	P15692	Vascular endothelial growth factor A	X-ray	2.50	2019-12-08	—	63.91	0.98	—	—	—	0.01	ok
6W39_A	O75460	Serine/threonine-protein kinase/endoribonu	X-ray	1.74	2020-03-09	—	72.69	0.98	—	—	—	0.01	ok
6ZJ5_AAA	Q5SRI9	Glycoprotein endo-alpha-1,2-mannosidase	X-ray	2.27	2020-06-27	—	86.44	0.99	—	—	—	0.01	ok
7K80_A	A0A5H2UYS3	MHC class I antigen	X-ray	2.40	2020-09-24	—	85.25	0.99	—	—	—	0.01	ok
6Z80_A	P30793	GTP cyclohydrolase 1	EM	3.00	2020-06-02	—	86.50	0.99	—	—	—	0.01	ok
6W3B_A	O75460	Serine/threonine-protein kinase/endoribonu	X-ray	2.57	2020-03-09	—	72.69	0.99	—	—	—	0.01	ok
7A49_A	P68400	Casein kinase II subunit alpha	X-ray	2.03	2020-08-19	—	88.94	0.99	—	—	—	0.01	ok
7D3F_A	Q9NRD9	Dual oxidase 1	EM	2.60	2020-09-19	—	85.62	0.99	—	—	—	0.01	ok
7A4B_A	P68400	Casein kinase II subunit alpha	X-ray	2.06	2020-08-19	—	88.94	0.99	—	—	—	0.01	ok
6W3K_A	O75460	Serine/threonine-protein kinase/endoribonu	X-ray	2.08	2020-03-09	—	72.69	0.99	—	—	—	0.01	ok
6W3C_A	O75460	Serine/threonine-protein kinase/endoribonu	X-ray	2.30	2020-03-09	—	72.69	0.99	—	—	—	0.01	ok
7ABH_E	Q15393	Splicing factor 3B subunit 3	EM	4.50	2020-09-07	—	92.25	0.99	—	—	—	0.01	ok
7A1Z_A	P19784	Casein kinase II subunit alpha'	X-ray	1.02	2020-08-14	—	94.12	0.99	—	—	—	0.01	ok
7A22_A	P19784	Casein kinase II subunit alpha'	X-ray	1.01	2020-08-15	—	94.12	0.99	—	—	—	0.01	ok
7A1B_A	P19784	Casein kinase II subunit alpha'	X-ray	1.29	2020-08-12	—	94.12	0.99	—	—	—	0.01	ok
7A2H_A	P19784	Casein kinase II subunit alpha'	X-ray	1.01	2020-08-18	—	94.12	0.99	—	—	—	0.01	ok
6UX9_A	P48426	Phosphatidylinositol 5-phosphate 4-kinase	X-ray	1.71	2019-11-07	—	85.69	1.00	—	—	—	0.00	ok
7A4C_A	P68400	Casein kinase II subunit alpha	X-ray	2.50	2020-08-19	—	88.94	1.00	—	—	—	0.00	ok
7D3E_B	Q1HG43	Isoform 2 of Dual oxidase maturation facto	EM	2.80	2020-09-19	—	82.44	1.00	—	—	—	0.00	ok
7D3F_B	Q1HG43	Isoform 2 of Dual oxidase maturation facto	EM	2.60	2020-09-19	—	82.44	1.00	—	—	—	0.00	ok
6V5K_A	Q9Y253	DNA polymerase eta	X-ray	2.69	2019-12-04	—	76.88	1.00	—	—	—	0.00	ok
6Z86_A	P30793	GTP cyclohydrolase 1	X-ray	2.21	2020-06-02	—	86.50	1.00	—	—	—	0.00	ok

Click a column header to sort. FRAUD = confidence-weighted error; a structure is flagged confidently wrong when mean pLDDT > 70 yet TM-score < 0.5.