Release week 2020-10-21
⭐ This week's notable releases
3 novel sequences, 0 confidently wrong. Highlight: Microcephalin.
| PDB | Protein | Flags | Why it matters |
|---|---|---|---|
|
|
Microcephalin | novel · 100% | Genuinely unseen sequence (0% identity to anything AlphaFold trained on). |
|
|
Tubulinyl-Tyr carboxypeptidase 1 | novel · 100% | Genuinely unseen sequence (0% identity to anything AlphaFold trained on) — AlphaFold predicted it correctly (TM 0.95). |
|
|
Small vasohibin-binding protein | novel · 100% | Genuinely unseen sequence (0% identity to anything AlphaFold trained on) — AlphaFold predicted it correctly (TM 0.89). |
Zoomed into the red "confidently wrong" box above (pLDDT ≥ 70, TM < 0.5) — the structures AlphaFold got confidently wrong.
How to read this
Every point is one experimental protein structure. The horizontal axis is AlphaFold's own confidence in its prediction (mean pLDDT, 0–100). The vertical axis is how well that blind prediction actually matches the experiment (TM-score, 0–1; above 0.5 means the same fold, above 0.9 near-identical). Marker size grows with the FRAUD score (confidence-weighted error).
Cutoff: the shaded red box is the "confidently wrong" zone — AlphaFold was confident (mean pLDDT above 70) yet the fold is wrong (TM-score below 0.5). A predictor that had truly solved folding would leave that box empty.
Take-home: 0 of 150 structures (0.0%) are confidently wrong; median TM-score is 0.952.
Read moreShow less — how each metric is calculated
TM-score: how similar the two 3D shapes are overall, 0–1 (a random pair scores ~0.17, an identical fold ~1). Length-normalised so large and small proteins compare fairly. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) — dᵢ is the gap between the i-th aligned Cα atoms after best-fit superposition, and d₀ = 1.24(L−15)^⅓ − 1.8 sets the distance scale for length L. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264; computed with TM-align, doi:10.1093/nar/gki524.
pLDDT: AlphaFold's own confidence in each residue, 0–100 (higher = surer). It is the model predicting its own accuracy before ever seeing the experiment. We plot the per-structure mean. pLDDT = (1/N) Σᵢ pLDDTᵢ, where pLDDTᵢ is the network's confidence output for residue i.
FRAUD score: the headline number — how wrong the prediction was, weighted by how confident AlphaFold was, so a big error it was sure about counts most. FRAUD = (1/N) Σᵢ (pLDDTᵢ/100) · min(Δᵢ,15)/15, where Δᵢ is residue i's Cα distance from the experiment (Å) after superposition, capped at 15 Å. Runs 0 (perfect) to 1.
Novelty: how little AlphaFold had to go on — 100 minus the highest sequence identity between this protein and any structure released before the 2018-04-30 training cutoff. High = genuinely unseen (100% = nothing similar was ever in the training set). novelty = 100 − maxₚ identity(s, p) over pre-cutoff PDB chains p, with identity = 100 × (matching aligned residues)/(alignment length), from an MMseqs2 search.
Homology: the point colour. High novelty (above 70%) flags the sequence as novel (amber) — AlphaFold had no close template; otherwise a pre-cutoff homolog existed (blue) it could have learned the fold from. novel ⇔ novelty > 70%.
What the metrics mean
TM-score (0–1): overall fold match — above 0.5 is the same fold, above 0.9 near-identical. Cα-RMSD (Å): average backbone distance after best-fit superposition — lower is better (under 2 Å is excellent). lDDT (0–1): local accuracy measured without superposition — above 0.8 is good. Each bar counts how many structures fall in that range.
Take-home: median TM-score 0.952 — most predictions match the experimental fold well, with a long tail that do not.
Read moreShow less — how each metric is calculated
TM-score: overall shape match, 0–1 (above 0.5 = same fold, above 0.9 near-identical), length-normalised. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) with dᵢ the aligned-Cα gap after superposition and d₀ = 1.24(L−15)^⅓ − 1.8. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264.
Cα-RMSD: the average straight-line distance between matching backbone Cα atoms once the two structures are best-fit superposed (Å; lower is better, under ~2 Å excellent). RMSD = √( (1/N) Σᵢ |Pᵢ − (R·Qᵢ + t)|² ), with Pᵢ/Qᵢ the experimental/model Cα coordinates and R,t the rotation and translation from Kabsch superposition.
lDDT: local accuracy with no superposition — the fraction of short-range inter-residue distances the model reproduces, so it is not fooled by a single wrongly-placed domain. lDDT = (1/N) Σᵢ ¼ Σ_t 1[ |d_exp − d_model| < t ] over thresholds t ∈ {0.5, 1, 2, 4} Å and all residue pairs within 15 Å.
Trend over time
The blue line is the mean TM-score of the structures by their deposit month; the red bars count how many were confidently wrong. Binning by deposit date (rather than by when we processed them) gives an even timeline, tracking whether AlphaFold's accuracy on newly-deposited structures is holding steady, improving, or slipping as the PDB keeps growing. Months with fewer than 5 structures are omitted so each point is a meaningful average. A dashed trend line is drawn only if the change over time is statistically significant.
Read moreShow less — how each metric is calculated
Mean TM-score: the month's average shape-match score. TM̄ = (1/M) Σ TM over the M structures deposited that month.
Trend line: a monotonic-trend test over the monthly means — Mann-Kendall (Kendall's τ) for significance, with a robust Theil-Sen slope for the line. Rank-based, so it tolerates the skewed TM distribution and noisy low-count months. Shown only when p < 0.05; otherwise a note reports that no significant trend was found.
Confidently wrong: the count that were both confident and wrong. count( mean pLDDT > 70 AND TM < 0.5 ).
Matched structures
| PDB | UniProt | Protein | Method | Å | Deposited | Novelty % | pLDDT | TM | lDDT | GDT_TS | RMSD | FRAUD | Flag |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 7K2V_A | Q9Y2I7 | 1-phosphatidylinositol 3-phosphate 5-kinas | EM | 6.60 | 2020-09-09 | 67.80 | 70.26 | 0.59 | 0.44 | 4.28 | 26.85 | 0.52 | ok |
| 6TL0_B | Q96NW4 | Ankyrin repeat domain-containing protein 2 | NMR | — | 2019-11-29 | 0.00 | 57.82 | 0.36 | 0.62 | 10.66 | 14.48 | 0.42 | ok |
| 6ZSA_t1 | P52815 | 39S ribosomal protein L12, mitochondrial | EM | 4.00 | 2020-07-15 | 9.50 | 85.32 | 0.58 | 0.82 | 24.46 | 9.25 | 0.37 | ok |
| 6ZSA_m | Q7Z7F7 | 39S ribosomal protein L55, mitochondrial | EM | 4.00 | 2020-07-15 | 0.00 | 92.36 | 0.65 | 0.84 | 30.42 | 7.21 | 0.36 | ok |
| 6L4K_A | P02768 | Serum albumin | X-ray | 2.09 | 2019-10-17 | 0.00 | 95.06 | 0.84 | 0.91 | 44.15 | 4.43 | 0.25 | ok |
| 6ZHE_C | P13010 | X-ray repair cross-complementing protein 5 | EM | 7.24 | 2020-06-23 | — | 83.12 | 0.72 | — | — | — | 0.23 | ok |
| 6ZSA_XH | Q9BYD2 | 39S ribosomal protein L9, mitochondrial | EM | 4.00 | 2020-07-15 | — | 81.69 | 0.72 | — | — | — | 0.23 | ok |
| 6ZSA_8 | Q9NQ50 | 39S ribosomal protein L40, mitochondrial | EM | 4.00 | 2020-07-15 | — | 78.75 | 0.72 | — | — | — | 0.22 | ok |
| 6ZHE_B | P12956 | X-ray repair cross-complementing protein 6 | EM | 7.24 | 2020-06-23 | — | 84.44 | 0.75 | — | — | — | 0.21 | ok |
| 6ZHA_B | P12956 | X-ray repair cross-complementing protein 6 | EM | 3.91 | 2020-06-21 | — | 84.44 | 0.76 | — | — | — | 0.20 | ok |
| 7D7N_A | Q9NP58 | ATP-binding cassette sub-family B member 6 | EM | 5.20 | 2020-10-05 | — | 83.06 | 0.76 | — | — | — | 0.20 | ok |
| 6ZSA_AZ | Q9Y291 | 28S ribosomal protein S33, mitochondrial | EM | 4.00 | 2020-07-15 | — | 91.19 | 0.80 | — | — | — | 0.18 | ok |
| 6ZSA_A0 | P82930 | 28S ribosomal protein S34, mitochondrial | EM | 4.00 | 2020-07-15 | — | 81.88 | 0.78 | — | — | — | 0.18 | ok |
| 6ZSA_p | Q14197 | Peptidyl-tRNA hydrolase ICT1, mitochondria | EM | 4.00 | 2020-07-15 | — | 84.44 | 0.80 | — | — | — | 0.17 | ok |
| 6ZH6_B | P13010 | X-ray repair cross-complementing protein 5 | EM | 3.93 | 2020-06-21 | 0.00 | 37.65 | 0.58 | 0.23 | 25.00 | 7.17 | 0.16 | ok |
| 6ZSA_a | Q9Y6G3 | 39S ribosomal protein L42, mitochondrial | EM | 4.00 | 2020-07-15 | — | 74.88 | 0.79 | — | — | — | 0.16 | ok |
| 7C5D_C | Q8NEM0 | Microcephalin | X-ray | 2.15 | 2020-05-19 | 100.00 novel | 33.17 | 0.35 | 0.34 | 21.88 | 6.74 | 0.14 | ok |
| 6ZSA_XI | Q7Z7H8 | 39S ribosomal protein L10, mitochondrial | EM | 4.00 | 2020-07-15 | — | 82.81 | 0.83 | — | — | — | 0.14 | ok |
| 6ZSA_l | Q6P161 | 39S ribosomal protein L54, mitochondrial | EM | 4.00 | 2020-07-15 | 0.00 | 89.01 | 0.69 | 0.83 | 61.25 | 2.67 | 0.14 | ok |
| 6LF0_A | Q96JP0 | Protein fem-1 homolog C | X-ray | 2.11 | 2019-11-27 | 64.10 | 95.10 | 0.93 | 0.93 | 68.43 | 5.20 | 0.14 | ok |
| 6ZSA_AU | Q9BYN8 | 28S ribosomal protein S26, mitochondrial | EM | 4.00 | 2020-07-15 | — | 89.06 | 0.85 | — | — | — | 0.13 | ok |
| 7K1W_F | Q92562 | Fig4 Sac homology model | EM | 5.10 | 2020-09-08 | — | 79.94 | 0.84 | — | — | — | 0.13 | ok |
| 6LPG_A | Q7L8A9 | Tubulinyl-Tyr carboxypeptidase 1 | X-ray | 2.30 | 2020-01-10 | 100.00 novel | 95.56 | 0.95 | 0.94 | 70.68 | 6.18 | 0.13 | ok |
| 6LBF_A | Q9UK73 | Protein fem-1 homolog B | X-ray | 3.25 | 2019-11-14 | 60.50 | 96.08 | 0.92 | 0.90 | 73.47 | 4.83 | 0.12 | ok |
| 6ZSA_XM | Q9P015 | 39S ribosomal protein L15, mitochondrial | EM | 4.00 | 2020-07-15 | — | 91.00 | 0.87 | — | — | — | 0.12 | ok |
| 6ZSA_XT | Q9NWU5 | 39S ribosomal protein L22, mitochondrial | EM | 4.00 | 2020-07-15 | — | 85.31 | 0.86 | — | — | — | 0.12 | ok |
| 6ZSA_6 | Q96DV4 | 39S ribosomal protein L38, mitochondrial | EM | 4.00 | 2020-07-15 | — | 82.81 | 0.86 | — | — | — | 0.12 | ok |
| 6ZSA_q | Q8TAE8 | Growth arrest and DNA damage-inducible pro | EM | 4.00 | 2020-07-15 | — | 86.56 | 0.87 | — | — | — | 0.11 | ok |
| 6LE6_A | Q96JP0 | Protein fem-1 homolog C,10-mer peptide | X-ray | 2.33 | 2019-11-24 | 64.10 | 95.47 | 0.95 | 0.89 | 77.23 | 5.32 | 0.11 | ok |
| 7K2V_P | Q9Y2I7 | 1-phosphatidylinositol 3-phosphate 5-kinas | EM | 6.60 | 2020-09-09 | — | 63.19 | 0.83 | — | — | — | 0.11 | ok |
| 6ZSA_AY | Q92665 | 28S ribosomal protein S31, mitochondrial | EM | 4.00 | 2020-07-15 | — | 66.12 | 0.84 | — | — | — | 0.11 | ok |
| 6ZSA_XK | Q9BYD1 | 39S ribosomal protein L13, mitochondrial | EM | 4.00 | 2020-07-15 | — | 93.19 | 0.89 | — | — | — | 0.11 | ok |
| 6TOQ_AAA | Q13362 | Serine/threonine-protein phosphatase 2A 56 | X-ray | 3.16 | 2019-12-11 | 0.00 | 95.72 | 0.95 | 0.91 | 75.68 | 2.35 | 0.11 | ok |
| 7A69_A | P08183 | Multidrug resistance protein 1 | EM | 3.20 | 2020-08-25 | — | 84.56 | 0.88 | — | — | — | 0.10 | ok |
| 6ZSA_o | Q9BQC6 | Ribosomal protein 63, mitochondrial | EM | 4.00 | 2020-07-15 | — | 92.38 | 0.89 | — | — | — | 0.10 | ok |
| 6ZSA_XV | Q96A35 | 39S ribosomal protein L24, mitochondrial | EM | 4.00 | 2020-07-15 | — | 88.88 | 0.89 | — | — | — | 0.10 | ok |
| 6ZSA_2 | Q9BQ48 | 39S ribosomal protein L34, mitochondrial | EM | 4.00 | 2020-07-15 | — | 79.62 | 0.88 | — | — | — | 0.10 | ok |
| 6LEN_A | Q96JP0 | Protein fem-1 homolog C,NS11 peptide | X-ray | 2.38 | 2019-11-25 | 64.10 | 95.79 | 0.95 | 0.91 | 82.38 | 4.46 | 0.09 | ok |
| 6ZSA_9 | Q8IXM3 | 39S ribosomal protein L41, mitochondrial | EM | 4.00 | 2020-07-15 | — | 90.94 | 0.91 | — | — | — | 0.08 | ok |
| 7A78_B | Q15596 | Nuclear receptor coactivator 2 | X-ray | 1.72 | 2020-08-27 | — | 64.10 | 0.59 | 0.84 | 75.00 | 2.30 | 0.08 | ok |
| 6VWC_A | Q07817 | Bcl-2-like protein 1 | X-ray | 1.60 | 2020-02-19 | — | 72.50 | 0.90 | — | — | — | 0.08 | ok |
| 7A79_C | Q15596 | Nuclear receptor coactivator 2 | X-ray | 2.05 | 2020-08-27 | — | 64.10 | 0.58 | 0.84 | 71.15 | 2.23 | 0.08 | ok |
| 6ZSA_A2 | Q96BP2 | Coiled-coil-helix-coiled-coil-helix domain | EM | 4.00 | 2020-07-15 | — | 92.38 | 0.92 | — | — | — | 0.07 | ok |
| 6ZSA_XQ | P49406 | 39S ribosomal protein L19, mitochondrial | EM | 4.00 | 2020-07-15 | — | 83.88 | 0.91 | — | — | — | 0.07 | ok |
| 6ZSA_AS | Q9Y3D9 | 28S ribosomal protein S23, mitochondrial | EM | 4.00 | 2020-07-15 | — | 77.31 | 0.91 | — | — | — | 0.07 | ok |
| 6ZSA_AE | P82932 | 28S ribosomal protein S6, mitochondrial | EM | 4.00 | 2020-07-15 | — | 92.69 | 0.92 | — | — | — | 0.07 | ok |
| 6ZSA_1 | O75394 | 39S ribosomal protein L33, mitochondrial | EM | 4.00 | 2020-07-15 | — | 91.25 | 0.92 | — | — | — | 0.07 | ok |
| 7D7R_A | Q9NP58 | ATP-binding cassette sub-family B member 6 | EM | 4.00 | 2020-10-05 | — | 83.06 | 0.92 | — | — | — | 0.07 | ok |
| 6ZSA_AJ | O15235 | 28S ribosomal protein S12, mitochondrial | EM | 4.00 | 2020-07-15 | — | 86.44 | 0.92 | — | — | — | 0.07 | ok |
| 7A77_B | Q15596 | Nuclear receptor coactivator 2 | X-ray | 1.50 | 2020-08-27 | — | 65.54 | 0.69 | 0.84 | 81.25 | 2.06 | 0.06 | ok |
| 6ZSA_e | Q9H2W6 | 39S ribosomal protein L46, mitochondrial | EM | 4.00 | 2020-07-15 | — | 79.69 | 0.92 | — | — | — | 0.06 | ok |
| 6ZDM_BBB | Q9Y251 | Heparanase | X-ray | 1.71 | 2020-06-14 | — | 94.69 | 0.94 | — | — | — | 0.06 | ok |
| 6ZSA_AO | Q9Y676 | 28S ribosomal protein S18b, mitochondrial | EM | 4.00 | 2020-07-15 | — | 82.19 | 0.93 | — | — | — | 0.06 | ok |
| 6ZSA_A1 | P82673 | 28S ribosomal protein S35, mitochondrial | EM | 4.00 | 2020-07-15 | — | 84.75 | 0.93 | — | — | — | 0.06 | ok |
| 6ZSA_XJ | Q9Y3B7 | 39S ribosomal protein L11, mitochondrial | EM | 4.00 | 2020-07-15 | — | 83.75 | 0.93 | — | — | — | 0.06 | ok |
| 6W4K_B | Q9UKL0 | REST corepressor 1 | X-ray | 2.93 | 2020-03-11 | — | 68.50 | 0.92 | — | — | — | 0.06 | ok |
| 7CRO_I | O96028 | Histone-lysine N-methyltransferase NSD2 | EM | 3.75 | 2020-08-14 | — | 65.62 | 0.92 | — | — | — | 0.06 | ok |
| 7JMS_B | P0CG47 | Polyubiquitin-B | X-ray | 2.78 | 2020-08-02 | — | 93.44 | 0.94 | — | — | — | 0.06 | ok |
| 7CRQ_I | Q9BZ95 | Histone-lysine N-methyltransferase NSD3 | EM | 3.15 | 2020-08-14 | — | 61.94 | 0.91 | — | — | — | 0.05 | ok |
| 6ZSA_i | Q4U2R6 | 39S ribosomal protein L51, mitochondrial | EM | 4.00 | 2020-07-15 | — | 85.88 | 0.94 | — | — | — | 0.05 | ok |
| 6ZSA_h | Q8N5N7 | 39S ribosomal protein L50, mitochondrial | EM | 4.00 | 2020-07-15 | — | 80.31 | 0.93 | — | — | — | 0.05 | ok |
| 7CRP_I | Q9BZ95 | Histone-lysine N-methyltransferase NSD3 | EM | 3.20 | 2020-08-14 | — | 61.94 | 0.92 | — | — | — | 0.05 | ok |
| 6ZSA_j | Q86TS9 | 39S ribosomal protein L52, mitochondrial | EM | 4.00 | 2020-07-15 | — | 85.50 | 0.94 | — | — | — | 0.05 | ok |
| 6ZSA_4 | Q9P0J6 | 39S ribosomal protein L36, mitochondrial | EM | 4.00 | 2020-07-15 | — | 71.50 | 0.93 | — | — | — | 0.05 | ok |
| 6ZSA_AT | P82663 | 28S ribosomal protein S25, mitochondrial | EM | 4.00 | 2020-07-15 | — | 92.44 | 0.95 | — | — | — | 0.05 | ok |
| 6OPN_C | P01730 | T-cell surface glycoprotein CD4 | EM | 3.50 | 2019-04-25 | 2.20 | 93.52 | 0.94 | 0.90 | 92.89 | 0.92 | 0.05 | ok |
| 6ZSA_g | Q13405 | 39S ribosomal protein L49, mitochondrial | EM | 4.00 | 2020-07-15 | — | 84.56 | 0.95 | — | — | — | 0.05 | ok |
| 6ZSA_f | Q96GC5 | 39S ribosomal protein L48, mitochondrial | EM | 4.00 | 2020-07-15 | — | 76.31 | 0.94 | — | — | — | 0.05 | ok |
| 6ZSA_AP | Q9Y3D5 | 28S ribosomal protein S18c, mitochondrial | EM | 4.00 | 2020-07-15 | — | 79.44 | 0.94 | — | — | — | 0.04 | ok |
| 6ZSA_A4 | Q96EY7 | Pentatricopeptide repeat domain-containing | EM | 4.00 | 2020-07-15 | — | 79.00 | 0.94 | — | — | — | 0.04 | ok |
| 6ZSA_AW | Q9Y2Q9 | 28S ribosomal protein S28, mitochondrial | EM | 4.00 | 2020-07-15 | — | 77.62 | 0.94 | — | — | — | 0.04 | ok |
| 7CRR_I | Q9BZ95 | Histone-lysine N-methyltransferase NSD3 | EM | 3.48 | 2020-08-14 | — | 61.94 | 0.93 | — | — | — | 0.04 | ok |
| 6ZSA_A3 | Q9NWT8 | Aurora kinase A-interacting protein | EM | 4.00 | 2020-07-15 | — | 67.69 | 0.94 | — | — | — | 0.04 | ok |
| 7CFT_A | P78348 | Acid-sensing ion channel 1 | EM | 3.90 | 2020-06-28 | — | 83.75 | 0.95 | — | — | — | 0.04 | ok |
| 7BTN_A | Q15181 | Inorganic pyrophosphatase | X-ray | 2.38 | 2020-04-02 | — | 96.19 | 0.96 | — | — | — | 0.04 | ok |
| 6ZHA_C | P13010 | X-ray repair cross-complementing protein 5 | EM | 3.91 | 2020-06-21 | — | 83.12 | 0.95 | — | — | — | 0.04 | ok |
| 6S96_A | Q16763 | Ubiquitin-conjugating enzyme E2 S | X-ray | 2.18 | 2019-07-11 | 0.70 | 95.86 | 0.97 | 0.93 | 94.30 | 0.97 | 0.04 | ok |
| 6X5C_C | P01730 | T-cell surface glycoprotein CD4 | EM | 4.04 | 2020-05-25 | — | 85.25 | 0.95 | — | — | — | 0.04 | ok |
| 6ZSA_AM | Q9Y3D3 | 28S ribosomal protein S16, mitochondrial | EM | 4.00 | 2020-07-15 | — | 90.62 | 0.96 | — | — | — | 0.04 | ok |
| 6ZSA_k | Q96EL3 | 39S ribosomal protein L53, mitochondrial | EM | 4.00 | 2020-07-15 | — | 80.69 | 0.95 | — | — | — | 0.04 | ok |
| 6ZSA_AQ | P82921 | 28S ribosomal protein S21, mitochondrial | EM | 4.00 | 2020-07-15 | — | 96.31 | 0.96 | — | — | — | 0.04 | ok |
| 7CFS_A | P78348 | Acid-sensing ion channel 1 | EM | 3.56 | 2020-06-28 | — | 83.75 | 0.95 | — | — | — | 0.04 | ok |
| 6ZSA_XS | Q7Z2W9 | 39S ribosomal protein L21, mitochondrial | EM | 4.00 | 2020-07-15 | — | 84.81 | 0.96 | — | — | — | 0.04 | ok |
| 7CZE_I | P29317 | Ephrin type-A receptor 2 | X-ray | 3.00 | 2020-09-08 | — | 82.25 | 0.96 | — | — | — | 0.03 | ok |
| 6X5B_C | P01730 | T-cell surface glycoprotein CD4 | EM | 3.60 | 2020-05-25 | — | 85.25 | 0.96 | — | — | — | 0.03 | ok |
| 6OPQ_C | P01730 | T-cell surface glycoprotein CD4 | EM | 3.80 | 2019-04-25 | 2.20 | 93.59 | 0.97 | 0.94 | 96.91 | 0.68 | 0.03 | ok |
| 6S98_A | Q16763 | Ubiquitin-conjugating enzyme E2 S | X-ray | 1.55 | 2019-07-11 | 0.00 | 95.92 | 0.98 | 0.96 | 97.13 | 0.86 | 0.03 | ok |
| 6ZSA_AK | O60783 | 28S ribosomal protein S14, mitochondrial | EM | 4.00 | 2020-07-15 | — | 86.19 | 0.96 | — | — | — | 0.03 | ok |
| 6ZSA_XR | Q9BYC9 | 39S ribosomal protein L20, mitochondrial | EM | 4.00 | 2020-07-15 | — | 91.00 | 0.96 | — | — | — | 0.03 | ok |
| 6ZSA_AN | Q9Y2R5 | 28S ribosomal protein S17, mitochondrial | EM | 4.00 | 2020-07-15 | — | 92.81 | 0.97 | — | — | — | 0.03 | ok |
| 6ZSA_AL | P82914 | 28S ribosomal protein S15, mitochondrial | EM | 4.00 | 2020-07-15 | — | 78.44 | 0.96 | — | — | — | 0.03 | ok |
| 6ZSA_AH | P82664 | 28S ribosomal protein S10, mitochondrial | EM | 4.00 | 2020-07-15 | — | 78.69 | 0.96 | — | — | — | 0.03 | ok |
| 7CM5_A | Q6SZW1 | NAD(+) hydrolase SARM1 | EM | 2.60 | 2020-07-24 | — | 85.69 | 0.96 | — | — | — | 0.03 | ok |
| 6ZSA_XU | Q16540 | 39S ribosomal protein L23, mitochondrial | EM | 4.00 | 2020-07-15 | — | 92.31 | 0.97 | — | — | — | 0.03 | ok |
| 7CM7_A | Q6SZW1 | NAD(+) hydrolase SARM1 | EM | 2.60 | 2020-07-25 | — | 85.69 | 0.96 | — | — | — | 0.03 | ok |
| 6ZSA_AV | Q92552 | 28S ribosomal protein S27, mitochondrial | EM | 4.00 | 2020-07-15 | — | 80.19 | 0.96 | — | — | — | 0.03 | ok |
| 6ZSA_0 | Q9BYC8 | 39S ribosomal protein L32, mitochondrial | EM | 4.00 | 2020-07-15 | — | 76.81 | 0.96 | — | — | — | 0.03 | ok |
| 6ZSA_AF | Q9Y2R9 | 28S ribosomal protein S7, mitochondrial | EM | 4.00 | 2020-07-15 | — | 86.81 | 0.97 | — | — | — | 0.03 | ok |
| 6OPP_C | P01730 | T-cell surface glycoprotein CD4 | EM | 3.70 | 2019-04-25 | 2.20 | 93.59 | 0.98 | 0.95 | 97.42 | 0.59 | 0.03 | ok |
| 7CZF_A | P29317 | Ephrin type-A receptor 2 | X-ray | 3.20 | 2020-09-08 | — | 82.25 | 0.97 | — | — | — | 0.03 | ok |
| 6ZSA_AG | P82933 | 28S ribosomal protein S9, mitochondrial | EM | 4.00 | 2020-07-15 | — | 82.06 | 0.97 | — | — | — | 0.03 | ok |
| 6Z8P_AAA | P25440 | Bromodomain-containing protein 2 | X-ray | 1.55 | 2020-06-02 | — | 64.06 | 0.96 | — | — | — | 0.03 | ok |
| 6OPO_C | P01730 | T-cell surface glycoprotein CD4 | EM | 3.50 | 2019-04-25 | 2.20 | 93.59 | 0.98 | 0.96 | 98.20 | 0.59 | 0.03 | ok |
| 7CM6_A | Q6SZW1 | NAD(+) hydrolase SARM1 | EM | 3.00 | 2020-07-25 | — | 85.69 | 0.97 | — | — | — | 0.03 | ok |
| 6LPG_B | Q8N300 | Small vasohibin-binding protein | X-ray | 2.30 | 2020-01-10 | 100.00 novel | 98.08 | 0.89 | 1.00 | 98.21 | 0.49 | 0.03 | ok |
| 6ZSA_XW | Q9P0M9 | 39S ribosomal protein L27, mitochondrial | EM | 4.00 | 2020-07-15 | — | 86.75 | 0.97 | — | — | — | 0.03 | ok |
| 6ZSA_AC | Q96EL2 | 28S ribosomal protein S24, mitochondrial | EM | 4.00 | 2020-07-15 | — | 86.06 | 0.97 | — | — | — | 0.03 | ok |
| 6ZSA_AD | P82675 | 28S ribosomal protein S5, mitochondrial | EM | 4.00 | 2020-07-15 | — | 81.88 | 0.97 | — | — | — | 0.03 | ok |
| 6ZSA_r | Q9NVS2 | 39S ribosomal protein S18a, mitochondrial | EM | 4.00 | 2020-07-15 | — | 85.69 | 0.97 | — | — | — | 0.03 | ok |
| 6Z1N_A | Q86SQ9 | Dehydrodolichyl diphosphate synthase compl | X-ray | 2.30 | 2020-05-14 | — | 94.75 | 0.97 | — | — | — | 0.02 | ok |
| 6ULB_A | P04278 | Sex hormone-binding globulin | X-ray | 1.75 | 2019-10-07 | 0.50 | 92.91 | 0.99 | 0.96 | 97.51 | 0.70 | 0.02 | ok |
| 6ZSA_XL | Q6P1L8 | 39S ribosomal protein L14, mitochondrial | EM | 4.00 | 2020-07-15 | — | 85.50 | 0.97 | — | — | — | 0.02 | ok |
| 6ZSA_XZ | Q8TCC3 | 39S ribosomal protein L30, mitochondrial | EM | 4.00 | 2020-07-15 | — | 82.75 | 0.97 | — | — | — | 0.02 | ok |
| 6ZSA_3 | Q9NZE8 | 39S ribosomal protein L35, mitochondrial | EM | 4.00 | 2020-07-15 | — | 74.62 | 0.97 | — | — | — | 0.02 | ok |
| 6ZSA_XY | Q9HD33 | 39S ribosomal protein L47, mitochondrial | EM | 4.00 | 2020-07-15 | — | 82.75 | 0.97 | — | — | — | 0.02 | ok |
| 6ZSA_XO | Q9NRX2 | 39S ribosomal protein L17, mitochondrial | EM | 4.00 | 2020-07-15 | — | 93.06 | 0.98 | — | — | — | 0.02 | ok |
| 6ZSA_AX | P51398 | 28S ribosomal protein S29, mitochondrial | EM | 4.00 | 2020-07-15 | — | 85.00 | 0.98 | — | — | — | 0.02 | ok |
| 6ZSA_AR | P82650 | 28S ribosomal protein S22, mitochondrial | EM | 4.00 | 2020-07-15 | — | 81.88 | 0.98 | — | — | — | 0.02 | ok |
| 6ZSA_XP | Q9H0U6 | 39S ribosomal protein L18, mitochondrial | EM | 4.00 | 2020-07-15 | — | 86.62 | 0.98 | — | — | — | 0.02 | ok |
| 7C5D_A | Q15554 | Telomeric repeat-binding factor 2 | X-ray | 2.15 | 2020-05-19 | — | 68.00 | 0.97 | — | — | — | 0.02 | ok |
| 6ZSA_XN | Q9NX20 | 39S ribosomal protein L16, mitochondrial | EM | 4.00 | 2020-07-15 | — | 88.75 | 0.98 | — | — | — | 0.02 | ok |
| 7A9U_AAA | O60885 | Bromodomain-containing protein 4 | X-ray | 1.44 | 2020-09-02 | — | 55.31 | 0.97 | — | — | — | 0.02 | ok |
| 6ZSA_XX | Q13084 | 39S ribosomal protein L28, mitochondrial | EM | 4.00 | 2020-07-15 | — | 92.31 | 0.98 | — | — | — | 0.02 | ok |
| 6ZSA_AI | P82912 | 28S ribosomal protein S11, mitochondrial | EM | 4.00 | 2020-07-15 | — | 82.94 | 0.98 | — | — | — | 0.02 | ok |
| 6ZSA_5 | Q9BZE1 | 39S ribosomal protein L37, mitochondrial | EM | 4.00 | 2020-07-15 | — | 89.06 | 0.98 | — | — | — | 0.02 | ok |
| 7KDT_A | O94826 | Mitochondrial import receptor subunit TOM7 | EM | 3.05 | 2020-10-09 | — | 80.06 | 0.98 | — | — | — | 0.01 | ok |
| 6TI9_A | P02766 | Transthyretin | X-ray | 1.45 | 2019-11-22 | 0.00 | 97.91 | 1.00 | 1.00 | 100.00 | 0.26 | 0.01 | ok |
| 6ZSA_7 | Q9NYK5 | 39S ribosomal protein L39, mitochondrial | EM | 4.00 | 2020-07-15 | — | 84.12 | 0.98 | — | — | — | 0.01 | ok |
| 6ZSA_b | Q8N983 | 39S ribosomal protein L43, mitochondrial | EM | 4.00 | 2020-07-15 | — | 82.75 | 0.98 | — | — | — | 0.01 | ok |
| 6ZSA_d | Q9BRJ2 | 39S ribosomal protein L45, mitochondrial | EM | 4.00 | 2020-07-15 | — | 80.62 | 0.98 | — | — | — | 0.01 | ok |
| 7A77_A | P19793 | Retinoic acid receptor RXR-alpha | X-ray | 1.50 | 2020-08-27 | — | 75.38 | 0.98 | — | — | — | 0.01 | ok |
| 6T27_A | P15121 | Aldo-keto reductase family 1 member B1 | X-ray | 1.11 | 2019-10-08 | 0.40 | 98.33 | 1.00 | 0.99 | 99.45 | 0.30 | 0.01 | ok |
| 6ZSA_c | Q9H9J2 | 39S ribosomal protein L44, mitochondrial | EM | 4.00 | 2020-07-15 | — | 88.00 | 0.99 | — | — | — | 0.01 | ok |
| 6ZSA_XE | P09001 | 39S ribosomal protein L3, mitochondrial | EM | 4.00 | 2020-07-15 | — | 86.75 | 0.99 | — | — | — | 0.01 | ok |
| 6ZSA_XF | Q9BYD3 | 39S ribosomal protein L4, mitochondrial | EM | 4.00 | 2020-07-15 | — | 83.75 | 0.99 | — | — | — | 0.01 | ok |
| 6ZOV_A | P98073 | Enteropeptidase | X-ray | 2.19 | 2020-07-07 | — | 81.50 | 0.99 | — | — | — | 0.01 | ok |
| 7CMO_A | Q15181 | Inorganic pyrophosphatase | X-ray | 3.40 | 2020-07-28 | — | 96.19 | 0.99 | — | — | — | 0.01 | ok |
| 6ZSA_XD | Q5T653 | 39S ribosomal protein L2, mitochondrial | EM | 4.00 | 2020-07-15 | — | 85.38 | 0.99 | — | — | — | 0.01 | ok |
| 6ZSA_s | Q9NP92 | 39S ribosomal protein S30, mitochondrial | EM | 4.00 | 2020-07-15 | — | 87.62 | 0.99 | — | — | — | 0.01 | ok |
| 7K2U_A | Q02127 | Dihydroorotate dehydrogenase (quinone), mi | X-ray | 1.73 | 2020-09-09 | — | 96.12 | 0.99 | — | — | — | 0.01 | ok |
| 6Z1N_B | Q96E22 | Dehydrodolichyl diphosphate synthase compl | X-ray | 2.30 | 2020-05-14 | — | 82.00 | 0.99 | — | — | — | 0.01 | ok |
| 6W4K_A | O60341 | Lysine-specific histone demethylase 1A | X-ray | 2.93 | 2020-03-11 | — | 84.19 | 0.99 | — | — | — | 0.01 | ok |
| 6ZSA_AB | Q9Y399 | 28S ribosomal protein S2, mitochondrial | EM | 4.00 | 2020-07-15 | — | 82.31 | 0.99 | — | — | — | 0.01 | ok |
| 7A78_A | P28702 | Retinoic acid receptor RXR-beta | X-ray | 1.72 | 2020-08-27 | — | 70.94 | 0.99 | — | — | — | 0.01 | ok |
| 6ZDM_AAA | Q9Y251 | Heparanase | X-ray | 1.71 | 2020-06-14 | — | 94.69 | 0.99 | — | — | — | 0.01 | ok |
| 7A79_A | P48443 | Retinoic acid receptor RXR-gamma | X-ray | 2.05 | 2020-08-27 | — | 73.88 | 0.99 | — | — | — | 0.00 | ok |
| 7JGL_A | P02794 | Ferritin heavy chain | X-ray | 2.34 | 2020-07-19 | — | 95.31 | 1.00 | — | — | — | 0.00 | ok |
| 6UZU_A | P00918 | Carbonic anhydrase 2 | X-ray | 1.50 | 2019-11-15 | — | 97.38 | 1.00 | — | — | — | 0.00 | ok |
| 7JGQ_A | P02794 | Ferritin heavy chain | X-ray | 3.01 | 2020-07-19 | — | 95.31 | 1.00 | — | — | — | 0.00 | ok |
| 6YL4_A | P34913 | Bifunctional epoxide hydrolase 2 | X-ray | 2.00 | 2020-04-06 | — | 93.31 | 1.00 | — | — | — | 0.00 | ok |
Click a column header to sort. FRAUD = confidence-weighted error; a structure is flagged confidently wrong when mean pLDDT > 70 yet TM-score < 0.5.