Release week 2020-08-12

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147

structures analysed (18 full · 12.2%)

32.0%

confidently wrong

10.7%

novel sequences

10.7%

novel & wrong

0.961

median TM-score

⭐ This week's notable releases

1 novel sequence, 3 confidently wrong. Highlight: Coiled-coil domain-containing protein 124.

PDB	Protein	Flags	Why it matters
6ZME_CE ↗	Coiled-coil domain-containing protein 124	novel · 100% confidently wrong	Genuinely unseen sequence (0% identity to anything AlphaFold trained on) — and AlphaFold got the fold wrong despite high confidence.
6L1U_A ↗	Alpha-synuclein	confidently wrong disease	A close pre-cutoff homolog existed (100% identity to 1XQ8_1) yet AlphaFold confidently missed the fold. Disease-linked.
6L1T_A ↗	Alpha-synuclein	confidently wrong disease	A close pre-cutoff homolog existed (100% identity to 1XQ8_1) yet AlphaFold confidently missed the fold. Disease-linked.

see all 147 structures ↓

Zoomed into the red "confidently wrong" box above (pLDDT ≥ 70, TM < 0.5) — the structures AlphaFold got confidently wrong.

The worst offenders ranked, one row per protein (AlphaFold has one model per sequence, so repeat depositions are collapsed — “×N” marks how many structures of that protein exist; the worst is shown). Each row joins what AlphaFold claimed (blue, pLDDT/100) to what the experiment showed (red, TM-score) — the longer the bar, the bigger the miss. Hover a dot to preview its Cα-deviation ribbon; click to open the full entry.

How to read this

Every point is one experimental protein structure. The horizontal axis is AlphaFold's own confidence in its prediction (mean pLDDT, 0–100). The vertical axis is how well that blind prediction actually matches the experiment (TM-score, 0–1; above 0.5 means the same fold, above 0.9 near-identical). Marker size grows with the FRAUD score (confidence-weighted error).

Cutoff: the shaded red box is the "confidently wrong" zone — AlphaFold was confident (mean pLDDT above 70) yet the fold is wrong (TM-score below 0.5). A predictor that had truly solved folding would leave that box empty.

Take-home: 3 of 147 structures (2.0%) are confidently wrong; median TM-score is 0.961.

Read moreShow less — how each metric is calculated

TM-score: how similar the two 3D shapes are overall, 0–1 (a random pair scores ~0.17, an identical fold ~1). Length-normalised so large and small proteins compare fairly. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) — dᵢ is the gap between the i-th aligned Cα atoms after best-fit superposition, and d₀ = 1.24(L−15)^⅓ − 1.8 sets the distance scale for length L. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264; computed with TM-align, doi:10.1093/nar/gki524.

pLDDT: AlphaFold's own confidence in each residue, 0–100 (higher = surer). It is the model predicting its own accuracy before ever seeing the experiment. We plot the per-structure mean. pLDDT = (1/N) Σᵢ pLDDTᵢ, where pLDDTᵢ is the network's confidence output for residue i.

FRAUD score: the headline number — how wrong the prediction was, weighted by how confident AlphaFold was, so a big error it was sure about counts most. FRAUD = (1/N) Σᵢ (pLDDTᵢ/100) · min(Δᵢ,15)/15, where Δᵢ is residue i's Cα distance from the experiment (Å) after superposition, capped at 15 Å. Runs 0 (perfect) to 1.

Novelty: how little AlphaFold had to go on — 100 minus the highest sequence identity between this protein and any structure released before the 2018-04-30 training cutoff. High = genuinely unseen (100% = nothing similar was ever in the training set). novelty = 100 − maxₚ identity(s, p) over pre-cutoff PDB chains p, with identity = 100 × (matching aligned residues)/(alignment length), from an MMseqs2 search.

Homology: the point colour. High novelty (above 70%) flags the sequence as novel (amber) — AlphaFold had no close template; otherwise a pre-cutoff homolog existed (blue) it could have learned the fold from. novel ⇔ novelty > 70%.

What the metrics mean

TM-score (0–1): overall fold match — above 0.5 is the same fold, above 0.9 near-identical. Cα-RMSD (Å): average backbone distance after best-fit superposition — lower is better (under 2 Å is excellent). lDDT (0–1): local accuracy measured without superposition — above 0.8 is good. Each bar counts how many structures fall in that range.

Take-home: median TM-score 0.961 — most predictions match the experimental fold well, with a long tail that do not.

Read moreShow less — how each metric is calculated

TM-score: overall shape match, 0–1 (above 0.5 = same fold, above 0.9 near-identical), length-normalised. TM = (1/L) Σᵢ 1/(1 + (dᵢ/d₀)²) with dᵢ the aligned-Cα gap after superposition and d₀ = 1.24(L−15)^⅓ − 1.8. Ref: Zhang & Skolnick, Proteins 2004 doi:10.1002/prot.20264.

Cα-RMSD: the average straight-line distance between matching backbone Cα atoms once the two structures are best-fit superposed (Å; lower is better, under ~2 Å excellent). RMSD = √( (1/N) Σᵢ |Pᵢ − (R·Qᵢ + t)|² ), with Pᵢ/Qᵢ the experimental/model Cα coordinates and R,t the rotation and translation from Kabsch superposition.

lDDT: local accuracy with no superposition — the fraction of short-range inter-residue distances the model reproduces, so it is not fooled by a single wrongly-placed domain. lDDT = (1/N) Σᵢ ¼ Σ_t 1[ |d_exp − d_model| < t ] over thresholds t ∈ {0.5, 1, 2, 4} Å and all residue pairs within 15 Å.

Trend over time

The blue line is the mean TM-score of the structures by their deposit month; the red bars count how many were confidently wrong. Binning by deposit date (rather than by when we processed them) gives an even timeline, tracking whether AlphaFold's accuracy on newly-deposited structures is holding steady, improving, or slipping as the PDB keeps growing. Months with fewer than 5 structures are omitted so each point is a meaningful average. A dashed trend line is drawn only if the change over time is statistically significant.

Read moreShow less — how each metric is calculated

Mean TM-score: the month's average shape-match score. TM̄ = (1/M) Σ TM over the M structures deposited that month.

Trend line: a monotonic-trend test over the monthly means — Mann-Kendall (Kendall's τ) for significance, with a robust Theil-Sen slope for the line. Rank-based, so it tolerates the skewed TM distribution and noisy low-count months. Shown only when p < 0.05; otherwise a note reports that no significant trend was found.

Confidently wrong: the count that were both confident and wrong. count( mean pLDDT > 70 AND TM < 0.5 ).

Matched structures

PDB	UniProt	Protein	Method	Å	Deposited	Novelty %	pLDDT	TM	lDDT	GDT_TS	RMSD	FRAUD	Flag
6L1U_A	P37840	Alpha-synuclein	EM	3.37	2019-09-30	0.00	84.77	0.19	0.28	0.00	38.45	0.84	wrong
6L1T_A	P37840	Alpha-synuclein	EM	3.22	2019-09-30	0.00	84.77	0.21	0.27	0.00	38.39	0.84	wrong
6ZME_CE	Q96CT7	Coiled-coil domain-containing protein 124	EM	3.00	2020-07-02	100.00 novel	88.74	0.50	0.95	8.33	19.58	0.70	wrong
6ZME_CH	P62495	Eukaryotic peptide chain release factor su	EM	3.00	2020-07-02	0.00	87.23	0.59	0.85	8.92	14.62	0.59	ok
6ZME_Lz	P62906	60S ribosomal protein L10a	EM	3.00	2020-07-02	0.00	79.20	0.65	0.52	34.45	6.88	0.27	ok
6ZME_LW	P83731	60S ribosomal protein L24	EM	3.00	2020-07-02	0.00	87.40	0.59	0.92	43.15	4.28	0.22	ok
6WI9_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	4.30	2020-04-09	—	89.56	0.78	—	—	—	0.20	ok
6ZME_Se	P62861	40S ribosomal protein S30	EM	3.00	2020-07-02	—	91.00	0.80	—	—	—	0.18	ok
6ZME_Lb	P47914	60S ribosomal protein L29	EM	3.00	2020-07-02	—	81.44	0.78	—	—	—	0.18	ok
7CML_A	P45984	Mitogen-activated protein kinase 9	X-ray	2.15	2020-07-28	—	81.44	0.79	—	—	—	0.17	ok
6ZME_Sf	P62979	Ubiquitin-40S ribosomal protein S27a	EM	3.00	2020-07-02	—	89.56	0.82	—	—	—	0.16	ok
6ZME_SR	P08708	40S ribosomal protein S17	EM	3.00	2020-07-02	—	86.25	0.82	—	—	—	0.16	ok
6WI9_A	P63092	Guanine nucleotide-binding protein G(s) su	EM	4.30	2020-04-09	—	91.31	0.84	—	—	—	0.15	ok
6ZME_Ln	P62945	60S ribosomal protein L41	EM	3.00	2020-07-02	—	94.31	0.86	—	—	—	0.13	ok
6WPW_C	P63092	Guanine nucleotide-binding protein G(s) su	EM	3.10	2020-04-28	—	91.31	0.86	—	—	—	0.12	ok
6WZG_A	P63092	Guanine nucleotide-binding protein G(s) su	EM	2.30	2020-05-13	—	91.31	0.86	—	—	—	0.12	ok
6ZME_Lt	P30050	60S ribosomal protein L12	EM	3.00	2020-07-02	—	70.94	0.82	—	—	—	0.12	ok
6U7N_A	Q9P121	Neurotrimin	X-ray	3.32	2019-09-03	22.80	94.56	0.90	0.92	68.55	2.15	0.12	ok
6YZ4_A	O14733	Dual specificity mitogen-activated protein	X-ray	1.70	2020-05-06	—	77.25	0.86	—	—	—	0.11	ok
6ZME_SM	P25398	40S ribosomal protein S12	EM	3.00	2020-07-02	—	80.38	0.87	—	—	—	0.11	ok
6ZME_Lj	P61927	60S ribosomal protein L37	EM	3.00	2020-07-02	—	89.50	0.88	—	—	—	0.10	ok
6WZG_P	P09683	Secretin	EM	2.30	2020-05-13	—	65.88	0.84	—	—	—	0.10	ok
6WI9_R	P47872	Secretin receptor	EM	4.30	2020-04-09	—	76.56	0.87	—	—	—	0.10	ok
6WI9_P	P09683	Secretin	EM	4.30	2020-04-09	—	65.88	0.85	—	—	—	0.10	ok
6YG2_A	O14733	Dual specificity mitogen-activated protein	X-ray	2.00	2020-03-27	—	77.25	0.87	—	—	—	0.10	ok
6YFZ_A	O14733	Dual specificity mitogen-activated protein	X-ray	1.90	2020-03-27	—	77.25	0.87	—	—	—	0.10	ok
6ZME_SP	P62841	40S ribosomal protein S15	EM	3.00	2020-07-02	—	86.44	0.89	—	—	—	0.10	ok
6ZME_Sd	P62273	40S ribosomal protein S29	EM	3.00	2020-07-02	—	93.69	0.90	—	—	—	0.09	ok
6Q2I_A	P33240	Cleavage stimulation factor subunit 2	NMR	—	2019-08-08	0.00	84.65	0.86	0.79	75.24	3.33	0.09	ok
6ZME_LR	P84098	60S ribosomal protein L19	EM	3.00	2020-07-02	—	94.75	0.90	—	—	—	0.09	ok
6WPW_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	3.10	2020-04-28	—	89.56	0.90	—	—	—	0.09	ok
6ZME_La	P46776	60S ribosomal protein L27a	EM	3.00	2020-07-02	—	93.75	0.90	—	—	—	0.09	ok
6ZME_Ls	P05388	60S acidic ribosomal protein P0	EM	3.00	2020-07-02	—	79.31	0.89	—	—	—	0.09	ok
6YG1_A	O14733	Dual specificity mitogen-activated protein	X-ray	2.22	2020-03-27	—	77.25	0.89	—	—	—	0.09	ok
6ZME_Sc	P62857	40S ribosomal protein S28	EM	3.00	2020-07-02	—	91.00	0.90	—	—	—	0.09	ok
6ZME_Ll	P62891	60S ribosomal protein L39	EM	3.00	2020-07-02	—	94.00	0.91	—	—	—	0.08	ok
6ZME_Sb	P42677	40S ribosomal protein S27	EM	3.00	2020-07-02	—	92.44	0.91	—	—	—	0.08	ok
6ZME_Lg	P49207	60S ribosomal protein L34	EM	3.00	2020-07-02	—	90.38	0.91	—	—	—	0.08	ok
6ZME_SL	P62280	40S ribosomal protein S11	EM	3.00	2020-07-02	—	88.06	0.91	—	—	—	0.08	ok
6YG0_A	O14733	Dual specificity mitogen-activated protein	X-ray	2.00	2020-03-27	—	77.25	0.90	—	—	—	0.08	ok
6ZME_SY	P62847	40S ribosomal protein S24	EM	3.00	2020-07-02	—	88.69	0.92	—	—	—	0.07	ok
6YG3_A	O14733	Dual specificity mitogen-activated protein	X-ray	2.05	2020-03-27	—	77.25	0.91	—	—	—	0.07	ok
6WZG_R	P47872	Secretin receptor	EM	2.30	2020-05-13	—	76.56	0.91	—	—	—	0.07	ok
6YG5_A	O14733	Dual specificity mitogen-activated protein	X-ray	2.40	2020-03-27	—	77.25	0.91	—	—	—	0.07	ok
6ZME_SU	P60866	40S ribosomal protein S20	EM	3.00	2020-07-02	—	85.25	0.93	—	—	—	0.06	ok
6YG4_A	O14733	Dual specificity mitogen-activated protein	X-ray	2.30	2020-03-27	—	77.25	0.92	—	—	—	0.06	ok
6KNR_A	P62508	Estrogen-related receptor gamma	X-ray	2.80	2019-08-07	1.30	95.02	0.96	0.94	90.43	1.50	0.06	ok
7JMG_A	P68106	Peptidyl-prolyl cis-trans isomerase FKBP1B	EM	4.50	2020-07-31	—	94.88	0.94	—	—	—	0.06	ok
7JMI_A	P68106	Peptidyl-prolyl cis-trans isomerase FKBP1B	EM	4.50	2020-07-31	—	94.88	0.94	—	—	—	0.06	ok
7JMH_A	P68106	Peptidyl-prolyl cis-trans isomerase FKBP1B	EM	4.50	2020-07-31	—	94.88	0.94	—	—	—	0.06	ok
7JMJ_A	P68106	Peptidyl-prolyl cis-trans isomerase FKBP1B	EM	4.50	2020-07-31	—	94.88	0.94	—	—	—	0.06	ok
7JMF_A	P68106	Peptidyl-prolyl cis-trans isomerase FKBP1B	EM	4.50	2020-07-31	—	94.88	0.94	—	—	—	0.06	ok
6ZME_SZ	P62851	40S ribosomal protein S25	EM	3.00	2020-07-02	—	73.25	0.92	—	—	—	0.06	ok
6PV6_A	P68106	Peptidyl-prolyl cis-trans isomerase FKBP1B	EM	4.50	2019-07-19	0.00	95.16	0.94	0.86	90.65	1.02	0.05	ok
6ZME_SS	P62269	40S ribosomal protein S18	EM	3.00	2020-07-02	—	88.69	0.94	—	—	—	0.05	ok
6ZME_LU	P35268	60S ribosomal protein L22	EM	3.00	2020-07-02	—	83.94	0.94	—	—	—	0.05	ok
6ZME_LJ	P62913	60S ribosomal protein L11	EM	3.00	2020-07-02	—	91.56	0.95	—	—	—	0.05	ok
6U6T_A	Q7Z3B1	Neuronal growth regulator 1	X-ray	3.01	2019-08-30	45.90	94.71	0.98	0.96	94.59	0.88	0.05	ok
6TY5_A	Q9NR97	Toll-like receptor 8	X-ray	2.79	2020-01-15	0.00	92.05	0.99	0.95	95.22	1.11	0.05	ok
6ZME_SH	P62081	40S ribosomal protein S7	EM	3.00	2020-07-02	—	86.88	0.95	—	—	—	0.05	ok
6ZME_Lh	P42766	60S ribosomal protein L35	EM	3.00	2020-07-02	—	94.56	0.95	—	—	—	0.04	ok
6WG5_A	Q9Y227	Ectonucleoside triphosphate diphosphohydro	X-ray	2.60	2020-04-04	—	87.25	0.95	—	—	—	0.04	ok
6ZME_Lm	P62987	Ubiquitin-60S ribosomal protein L40	EM	3.00	2020-07-02	—	93.50	0.95	—	—	—	0.04	ok
6UIQ_A	P36871	phosphoglucomutase-1	X-ray	2.30	2019-10-01	0.00	97.12	0.99	0.98	93.91	0.88	0.04	ok
6ZME_LF	P18124	60S ribosomal protein L7	EM	3.00	2020-07-02	—	93.94	0.95	—	—	—	0.04	ok
6ZME_CA	Q9UQ80	Proliferation-associated protein 2G4	EM	3.00	2020-07-02	—	92.56	0.95	—	—	—	0.04	ok
6ZME_SG	P62753	40S ribosomal protein S6	EM	3.00	2020-07-02	—	94.19	0.96	—	—	—	0.04	ok
6SYF_A	P63279	SUMO-conjugating enzyme UBC9	X-ray	1.90	2019-09-27	0.70	98.00	0.97	0.96	95.59	0.77	0.04	ok
6ZME_Lp	P61513	60S ribosomal protein L37a	EM	3.00	2020-07-02	—	96.31	0.96	—	—	—	0.04	ok
6ZME_Lo	P83881	60S ribosomal protein L36a	EM	3.00	2020-07-02	—	94.31	0.96	—	—	—	0.04	ok
6ZME_LT	P46778	60S ribosomal protein L21	EM	3.00	2020-07-02	—	94.06	0.96	—	—	—	0.04	ok
6ZME_SI	P62241	40S ribosomal protein S8	EM	3.00	2020-07-02	—	93.00	0.96	—	—	—	0.04	ok
6ZME_SQ	P62249	40S ribosomal protein S16	EM	3.00	2020-07-02	—	93.88	0.96	—	—	—	0.04	ok
6ZME_Li	Q9Y3U8	60S ribosomal protein L36	EM	3.00	2020-07-02	—	93.12	0.96	—	—	—	0.04	ok
6ZME_SV	P63220	40S ribosomal protein S21	EM	3.00	2020-07-02	—	95.50	0.96	—	—	—	0.04	ok
6ZME_LX	P62750	60S ribosomal protein L23a	EM	3.00	2020-07-02	—	89.31	0.96	—	—	—	0.04	ok
6WZG_G	P59768	Guanine nucleotide-binding protein G(I)/G(	EM	2.30	2020-05-13	—	89.56	0.96	—	—	—	0.04	ok
6YG7_A	O14733	Dual specificity mitogen-activated protein	X-ray	2.20	2020-03-27	—	77.25	0.95	—	—	—	0.04	ok
6ZME_LL	P26373	60S ribosomal protein L13	EM	3.00	2020-07-02	—	95.38	0.96	—	—	—	0.03	ok
6ZME_SD	P23396	40S ribosomal protein S3	EM	3.00	2020-07-02	—	91.06	0.96	—	—	—	0.03	ok
6WPK_A	Q6SZW1	NAD(+) hydrolase SARM1	EM	3.30	2020-04-27	—	85.69	0.96	—	—	—	0.03	ok
6ZME_SO	P62263	40S ribosomal protein S14	EM	3.00	2020-07-02	—	90.12	0.96	—	—	—	0.03	ok
6ZME_SK	P46783	40S ribosomal protein S10	EM	3.00	2020-07-02	—	73.81	0.96	—	—	—	0.03	ok
6ZME_LG	P62424	60S ribosomal protein L7a	EM	3.00	2020-07-02	—	90.62	0.96	—	—	—	0.03	ok
6UKA_A	P84095	Rho-related GTP-binding protein RhoG	X-ray	2.40	2019-10-04	28.20	96.55	0.99	0.97	98.16	0.60	0.03	ok
6SUZ_A	P04156	Major prion protein	X-ray	2.50	2019-09-17	1.10	86.00	0.97	0.95	95.96	0.73	0.03	ok
6ZME_SX	P62266	40S ribosomal protein S23	EM	3.00	2020-07-02	—	94.88	0.97	—	—	—	0.03	ok
6ZME_CI	P61221	ATP-binding cassette sub-family E member 1	EM	3.00	2020-07-02	—	86.69	0.96	—	—	—	0.03	ok
6YG6_A	O14733	Dual specificity mitogen-activated protein	X-ray	2.15	2020-03-27	—	77.25	0.96	—	—	—	0.03	ok
6ZME_LE	Q02878	60S ribosomal protein L6	EM	3.00	2020-07-02	—	82.81	0.96	—	—	—	0.03	ok
6ZME_Lc	P62888	60S ribosomal protein L30	EM	3.00	2020-07-02	—	88.00	0.97	—	—	—	0.03	ok
6ZME_Sa	P62854	40S ribosomal protein S26	EM	3.00	2020-07-02	—	85.81	0.97	—	—	—	0.03	ok
6ZME_LC	P36578	60S ribosomal protein L4	EM	3.00	2020-07-02	—	87.12	0.97	—	—	—	0.03	ok
6ZME_LD	P46777	60S ribosomal protein L5	EM	3.00	2020-07-02	—	94.50	0.97	—	—	—	0.03	ok
6WTH_C	P51170	Amiloride-sensitive sodium channel subunit	EM	3.06	2020-05-02	—	80.06	0.97	—	—	—	0.03	ok
6ZME_LM	P50914	60S ribosomal protein L14	EM	3.00	2020-07-02	—	76.56	0.97	—	—	—	0.03	ok
6Y7Q_AAA	Q9NS40	Potassium voltage-gated channel subfamily	X-ray	1.39	2020-03-02	—	66.56	0.96	—	—	—	0.03	ok
6WPW_R	P47871	Glucagon receptor	EM	3.10	2020-04-28	—	81.88	0.97	—	—	—	0.03	ok
6ZME_Lk	P63173	60S ribosomal protein L38	EM	3.00	2020-07-02	—	95.38	0.97	—	—	—	0.02	ok
6ZME_LV	P62829	60S ribosomal protein L23	EM	3.00	2020-07-02	—	92.62	0.97	—	—	—	0.02	ok
6KO2_A	O60885	Bromodomain-containing protein 4	X-ray	1.50	2019-08-07	0.00	95.79	0.98	0.97	98.60	0.62	0.02	ok
6ZME_Ld	P62899	60S ribosomal protein L31	EM	3.00	2020-07-02	—	87.94	0.97	—	—	—	0.02	ok
6ZME_SJ	P46781	40S ribosomal protein S9	EM	3.00	2020-07-02	—	88.12	0.97	—	—	—	0.02	ok
6ZME_Le	P62910	60S ribosomal protein L32	EM	3.00	2020-07-02	—	92.38	0.97	—	—	—	0.02	ok
6KLZ_A	P00918	Carbonic anhydrase 2	X-ray	0.90	2019-07-30	0.00	97.89	1.00	0.98	99.32	0.40	0.02	ok
6ZME_SB	P61247	40S ribosomal protein S3a	EM	3.00	2020-07-02	—	82.94	0.98	—	—	—	0.02	ok
6ZWP_A	Q16539	Mitogen-activated protein kinase 14	X-ray	1.90	2020-07-28	—	89.75	0.98	—	—	—	0.02	ok
6ZME_LY	P61254	60S ribosomal protein L26	EM	3.00	2020-07-02	—	92.88	0.98	—	—	—	0.02	ok
6WI9_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	4.30	2020-04-09	—	97.06	0.98	—	—	—	0.02	ok
6ZME_Sg	P63244	Receptor of activated protein C kinase 1	EM	3.00	2020-07-02	—	92.44	0.98	—	—	—	0.02	ok
6ZME_ST	P39019	40S ribosomal protein S19	EM	3.00	2020-07-02	—	92.00	0.98	—	—	—	0.02	ok
6ZME_SF	P46782	40S ribosomal protein S5	EM	3.00	2020-07-02	—	90.44	0.98	—	—	—	0.02	ok
6ZME_SN	P62277	40S ribosomal protein S13	EM	3.00	2020-07-02	—	94.06	0.98	—	—	—	0.02	ok
6ZME_LH	P32969	60S ribosomal protein L9	EM	3.00	2020-07-02	—	94.12	0.98	—	—	—	0.02	ok
6ZME_Lf	P18077	60S ribosomal protein L35a	EM	3.00	2020-07-02	—	95.56	0.98	—	—	—	0.02	ok
6ZME_LQ	Q07020	60S ribosomal protein L18	EM	3.00	2020-07-02	—	95.50	0.98	—	—	—	0.01	ok
6ZME_SC	P15880	40S ribosomal protein S2	EM	3.00	2020-07-02	—	80.94	0.98	—	—	—	0.01	ok
6ZME_LI	Q96L21	60S ribosomal protein L10-like	EM	3.00	2020-07-02	—	94.75	0.98	—	—	—	0.01	ok
7JH2_A	P51449	Nuclear receptor ROR-gamma	X-ray	2.37	2020-07-20	—	74.19	0.98	—	—	—	0.01	ok
6ZME_SW	P62244	40S ribosomal protein S15a	EM	3.00	2020-07-02	—	93.06	0.99	—	—	—	0.01	ok
6ZME_SA	P08865	40S ribosomal protein SA	EM	3.00	2020-07-02	—	79.25	0.98	—	—	—	0.01	ok
6ZME_Lr	P46779	60S ribosomal protein L28	EM	3.00	2020-07-02	—	92.69	0.99	—	—	—	0.01	ok
6ZME_LZ	P61353	60S ribosomal protein L27	EM	3.00	2020-07-02	—	94.31	0.99	—	—	—	0.01	ok
6WTH_A	P37088	Amiloride-sensitive sodium channel subunit	EM	3.06	2020-05-02	—	74.56	0.98	—	—	—	0.01	ok
6ZME_LO	P40429	60S ribosomal protein L13a	EM	3.00	2020-07-02	—	95.75	0.99	—	—	—	0.01	ok
6XNJ_A	Q9HD26	Golgi-associated PDZ and coiled-coil motif	X-ray	1.85	2020-07-03	—	69.12	0.98	—	—	—	0.01	ok
6ZME_LS	Q02543	60S ribosomal protein L18a	EM	3.00	2020-07-02	—	96.31	0.99	—	—	—	0.01	ok
6ZME_LP	P18621	60S ribosomal protein L17	EM	3.00	2020-07-02	—	91.88	0.99	—	—	—	0.01	ok
6XFV_A	P51449	Nuclear receptor ROR-gamma	X-ray	2.15	2020-06-16	—	74.19	0.98	—	—	—	0.01	ok
7CMR_A	Q9H7Z6	Histone acetyltransferase KAT8	X-ray	2.20	2020-07-28	—	81.69	0.99	—	—	—	0.01	ok
7CBK_B	P08246	Neutrophil elastase	X-ray	2.70	2020-06-12	—	88.19	0.99	—	—	—	0.01	ok
6ZME_LB	P39023	60S ribosomal protein L3	EM	3.00	2020-07-02	—	96.38	0.99	—	—	—	0.01	ok
6ZME_LN	P61313	60S ribosomal protein L15	EM	3.00	2020-07-02	—	96.19	0.99	—	—	—	0.01	ok
6WTH_B	P51168	Amiloride-sensitive sodium channel subunit	EM	3.06	2020-05-02	—	82.44	0.99	—	—	—	0.01	ok
6ZME_LA	P62917	60S ribosomal protein L8	EM	3.00	2020-07-02	—	95.31	0.99	—	—	—	0.01	ok
6V9U_A	Q9NR97	Toll-like receptor 8	X-ray	2.65	2019-12-16	—	86.12	0.99	—	—	—	0.01	ok
6WPW_D	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	3.10	2020-04-28	—	97.06	0.99	—	—	—	0.01	ok
6XIH_A	Q99683	Mitogen-activated protein kinase kinase ki	X-ray	2.65	2020-06-19	—	72.88	0.99	—	—	—	0.01	ok
6ZME_SE	P62701	40S ribosomal protein S4, X isoform	EM	3.00	2020-07-02	—	95.56	0.99	—	—	—	0.01	ok
6WZG_B	P62873	Guanine nucleotide-binding protein G(I)/G(	EM	2.30	2020-05-13	—	97.06	1.00	—	—	—	0.00	ok
6X48_A	Q99523	Sortilin	X-ray	2.90	2020-05-22	—	82.88	0.99	—	—	—	0.00	ok
6X3L_A	Q99523	Sortilin	X-ray	2.70	2020-05-21	—	82.88	1.00	—	—	—	0.00	ok
6YMB_A	P00918	carbonic anhydrase 2	EM	2.50	2020-04-08	—	97.38	1.00	—	—	—	0.00	ok
6YMA_A	P00918	carbonic anhydrase 2	EM	2.50	2020-04-08	—	97.38	1.00	—	—	—	0.00	ok
6X4H_A	Q99523	Sortilin	X-ray	2.90	2020-05-22	—	82.88	1.00	—	—	—	0.00	ok
6XEB_A	Q92769	Histone deacetylase 2	X-ray	1.50	2020-06-12	—	85.56	1.00	—	—	—	0.00	ok
6XEC_A	Q92769	Histone deacetylase 2	X-ray	1.70	2020-06-12	—	85.56	1.00	—	—	—	0.00	ok

Click a column header to sort. FRAUD = confidence-weighted error; a structure is flagged confidently wrong when mean pLDDT > 70 yet TM-score < 0.5.