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New PDB Depositions vs. Their Blind AlphaFold Predictions — A Running Test of “Is Folding Solved?”

9FMB_A

Isoform 1 of Immunoglobulin heavy constant delta · P01880 · RCSB 9FMB · AF-P01880-F1 (v6)

Screen-only record. This structure passed the fast TM-score screen (TM 0.76) and AlphaFold agrees well with experiment, so the full metric suite, novelty score and heatmaps were not computed. Full analysis is reserved for the disagreements (TM below the screening threshold).
0.76
TM-score
lDDT
Cα-RMSD Å
72.94
mean pLDDT
0.18
FRAUD score
—%
novelty

All metrics

Global fold agreement

TM-score (norm. experiment)0.76
TM-score (norm. model)0.38
TM-score (norm. shorter)0.76
TM-score (norm. longer)0.38

Local, superposition-free

Backbone & secondary structure

Confidence calibration

mean pLDDT72.94

Context & headline

FRAUD score0.18

Deposited 2024-06-05 · released 2024-12-04 · X-ray · 3.0 Å · closest pre-cutoff chain: none