___ __ __ ______ __ / | / /___ / /_ ____ _/ ____/________ ___ ______/ / / /| | / / __ \/ __ \/ __ `/ /_ / ___/ __ `/ / / / __ / / ___ |/ / /_/ / / / / /_/ / __/ / / / /_/ / /_/ / /_/ / /_/ |_/_/ .___/_/ /_/\__,_/_/ /_/ \__,_/\__,_/\__,_/ /_/

8EEC_A

Isoform 2 of Mitogen-activated protein kinase kinase kinase kinase 1 · Q92918 · RCSB 8EEC · AF-Q92918-F1 (v6)

Screen-only record. This structure passed the fast TM-score screen (TM 0.89) and AlphaFold agrees well with experiment, so the full metric suite, novelty score and heatmaps were not computed. Full analysis is reserved for the disagreements (TM below the screening threshold).

0.89

TM-score

lDDT

Cα-RMSD Å

68.19

mean pLDDT

0.07

FRAUD score

—%

novelty

All metrics

Global fold agreement

TM-score (norm. experiment)	0.89
TM-score (norm. model)	0.35
TM-score (norm. shorter)	0.89
TM-score (norm. longer)	0.35

Local, superposition-free

Backbone & secondary structure

Confidence calibration

mean pLDDT

68.19

Context & headline

FRAUD score

0.07

Deposited 2022-09-06 · released 2024-03-27 · X-ray · 2.5 Å · closest pre-cutoff chain: none