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New PDB Depositions vs. Their Blind AlphaFold Predictions — A Running Test of “Is Folding Solved?”

7EAA_A

Calcium-binding and coiled-coil domain-containing protein 2 · Q13137 · RCSB 7EAA · AF-Q13137-F1 (v6)

Screen-only record. This structure passed the fast TM-score screen (TM 0.93) and AlphaFold agrees well with experiment, so the full metric suite, novelty score and heatmaps were not computed. Full analysis is reserved for the disagreements (TM below the screening threshold).
0.93
TM-score
lDDT
Cα-RMSD Å
80.19
mean pLDDT
0.06
FRAUD score
—%
novelty

All metrics

Global fold agreement

TM-score (norm. experiment)0.93
TM-score (norm. model)0.22
TM-score (norm. shorter)0.93
TM-score (norm. longer)0.22

Local, superposition-free

Backbone & secondary structure

Confidence calibration

mean pLDDT80.19

Context & headline

FRAUD score0.06

Deposited 2021-03-06 · released 2021-12-22 · X-ray · 2.6 Å · closest pre-cutoff chain: none