new PDB depositions vs. their blind AlphaFold predictions — a running test of "is folding solved?"

36OL_A

GTPase KRas · P01116 · RCSB 36OL · AF-P01116-F1 (v6)

0.9844
TM-score
0.9773
lDDT
0.497
Cα-RMSD Å
95.13
mean pLDDT
0.024
FRAUD score
100.0%
novelty (max id)

Per-domain breakdown

SourceDomainRangeResiduesTMRMSD Åmean Cα ΔName
PAEPAE:1-1891-189 1680.9902 0.4970.385

All metrics

Global fold agreement

TM-score (norm. experiment)0.9844
TM-score (norm. model)0.8811
TM-score (norm. shorter)0.9844
TM-score (norm. longer)0.8811
Cα-RMSD (Å)0.497
backbone-RMSD (Å)0.512
all-atom-RMSD (Å)0.963
core-RMSD (Å)0.448
core fraction0.994
GDT_TS98.96
GDT_HA92.56
MaxSub0.9902
structural overlap (3.5 Å)1.0

Local, superposition-free

lDDT0.9773
contact-map Jaccard0.9264
contact precision0.9649
contact recall0.9587
distance-matrix mean Δ (Å)0.257
CAD-score (approx)0.9234

Backbone & secondary structure

SS agreement Q3 (%)94.64
mean Δφ (°)8.0
mean Δψ (°)7.2
torsion within 30° (frac)0.9643
Rg experiment (Å)14.67
Rg model (Å)14.57
ΔRg (Å)0.1

Confidence calibration

mean pLDDT95.13
pLDDT↔lDDT Pearson0.3778
pLDDT↔lDDT Spearman0.3975
PAE↔observed Pearson0.2434
PAE overconfident frac0.0
mean PAE (Å)4.291
mean observed error (Å)0.255

Context & headline

coverage of model0.8889
coverage of experiment0.9941
seq identity aligned (%)96.43
confidently-wrong residue frac0.0
FRAUD score0.024

Deposited 2026-06-23 · released 2026-07-01 · X-ray · 2.05 Å · closest pre-cutoff chain: 2MSC_2