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new PDB depositions vs. their blind AlphaFold predictions — a running test of "is folding solved?"

36OJ_A

Isoform 2B of GTPase KRas · P01116 · RCSB 36OJ · AF-P01116-F1 (v6)

0.9748

TM-score

0.9566

lDDT

0.77

Cα-RMSD Å

95.11

mean pLDDT

0.0304

FRAUD score

99.4%

novelty (max id)

Per-domain breakdown

Source	Domain	Range	Residues	TM	RMSD Å	mean Cα Δ	Name
PAE	PAE:1-189	1-189	169	0.9802	0.77	0.504

All metrics

Global fold agreement

TM-score (norm. experiment)	0.9748
TM-score (norm. model)	0.8782
TM-score (norm. shorter)	0.9748
TM-score (norm. longer)	0.8782
Cα-RMSD (Å)	0.77
backbone-RMSD (Å)	0.759
all-atom-RMSD (Å)	1.4
core-RMSD (Å)	0.464
core fraction	0.964
GDT_TS	97.19
GDT_HA	90.38
MaxSub	0.9866
structural overlap (3.5 Å)	0.9822

Local, superposition-free

lDDT	0.9566
contact-map Jaccard	0.9228
contact precision	0.9553
contact recall	0.9645
distance-matrix mean Δ (Å)	0.324
CAD-score (approx)	0.8973

Backbone & secondary structure

SS agreement Q3 (%)	94.08
mean Δφ (°)	7.9
mean Δψ (°)	8.3
torsion within 30° (frac)	0.9408
Rg experiment (Å)	14.69
Rg model (Å)	14.62
ΔRg (Å)	0.07

Confidence calibration

mean pLDDT	95.11
pLDDT↔lDDT Pearson	0.7694
pLDDT↔lDDT Spearman	0.626
PAE↔observed Pearson	0.4507
PAE overconfident frac	0.0
mean PAE (Å)	4.306
mean observed error (Å)	0.322

Context & headline

coverage of model	0.8942
coverage of experiment	0.9941
seq identity aligned (%)	95.86
confidently-wrong residue frac	0.0
FRAUD score	0.0304

Deposited 2026-06-23 · released 2026-07-01 · X-ray · 1.74 Å · closest pre-cutoff chain: 2MSC_2