new PDB depositions vs. their blind AlphaFold predictions — a running test of "is folding solved?"

31RU_A

Serine/threonine-protein kinase pim-1 · P11309 · RCSB 31RU · AF-P11309-F1 (v6)

0.9935
TM-score
0.9749
lDDT
0.535
Cα-RMSD Å
97.04
mean pLDDT
0.0215
FRAUD score
100.0%
novelty (max id)

Per-domain breakdown

SourceDomainRangeResiduesTMRMSD Åmean Cα ΔName
PAEPAE:1-3131-313 2730.9934 0.5350.34

All metrics

Global fold agreement

TM-score (norm. experiment)0.9935
TM-score (norm. model)0.8671
TM-score (norm. shorter)0.9935
TM-score (norm. longer)0.8671
Cα-RMSD (Å)0.535
backbone-RMSD (Å)0.563
all-atom-RMSD (Å)1.007
core-RMSD (Å)0.382
core fraction0.985
GDT_TS98.63
GDT_HA95.24
MaxSub0.9948
structural overlap (3.5 Å)0.9963

Local, superposition-free

lDDT0.9749
contact-map Jaccard0.9254
contact precision0.9684
contact recall0.9543
distance-matrix mean Δ (Å)0.244
CAD-score (approx)0.92

Backbone & secondary structure

SS agreement Q3 (%)95.24
mean Δφ (°)7.5
mean Δψ (°)9.1
torsion within 30° (frac)0.9451
Rg experiment (Å)18.55
Rg model (Å)18.58
ΔRg (Å)0.03

Confidence calibration

mean pLDDT97.04
pLDDT↔lDDT Pearson0.5608
pLDDT↔lDDT Spearman0.5642
PAE↔observed Pearson0.511
PAE overconfident frac0.0
mean PAE (Å)2.638
mean observed error (Å)0.244

Context & headline

coverage of model0.8722
coverage of experiment1.0
seq identity aligned (%)99.63
confidently-wrong residue frac0.0037
FRAUD score0.0215

Deposited 2026-06-18 · released 2026-07-01 · X-ray · 2.3 Å · closest pre-cutoff chain: 3CXW_1