new PDB depositions vs. their blind AlphaFold predictions — a running test of "is folding solved?"

27XK_R

Glucagon-like peptide 1 receptor · P43220 · RCSB 27XK · AF-P43220-F1 (v6)

0.797
TM-score
0.8606
lDDT
4.645
Cα-RMSD Å
88.02
mean pLDDT
0.2378
FRAUD score
99.7%
novelty (max id)

Per-domain breakdown

SourceDomainRangeResiduesTMRMSD Åmean Cα ΔName
PAEPAE:1-4631-463 3910.7548 4.6454.106

All metrics

Global fold agreement

TM-score (norm. experiment)0.797
TM-score (norm. model)0.6836
TM-score (norm. shorter)0.797
TM-score (norm. longer)0.6836
Cα-RMSD (Å)4.645
backbone-RMSD (Å)4.627
all-atom-RMSD (Å)5.002
core-RMSD (Å)0.648
core fraction0.55
GDT_TS41.69
GDT_HA18.54
MaxSub0.8954
structural overlap (3.5 Å)0.468

Local, superposition-free

lDDT0.8606
contact-map Jaccard0.7126
contact precision0.809
contact recall0.8567
distance-matrix mean Δ (Å)2.076
CAD-score (approx)0.8478

Backbone & secondary structure

SS agreement Q3 (%)87.98
mean Δφ (°)15.1
mean Δψ (°)20.3
torsion within 30° (frac)0.7877
Rg experiment (Å)31.12
Rg model (Å)29.71
ΔRg (Å)1.41

Confidence calibration

mean pLDDT88.02
pLDDT↔lDDT Pearson0.654
pLDDT↔lDDT Spearman0.6166
PAE↔observed Pearson0.567
PAE overconfident frac0.0014
mean PAE (Å)11.165
mean observed error (Å)2.071

Context & headline

coverage of model0.8445
coverage of experiment1.0
seq identity aligned (%)100.0
confidently-wrong residue frac0.3785
FRAUD score0.2378

Deposited 2026-06-16 · released 2026-07-01 · EM · 2.64 Å · closest pre-cutoff chain: 6B3J_1