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new PDB depositions vs. their blind AlphaFold predictions — a running test of "is folding solved?"

27XK_C

Glucagon-like peptide 1(7-36) · P01275 · RCSB 27XK · AF-P01275-F1 (v6)

0.7875

TM-score

0.8275

lDDT

4.832

Cα-RMSD Å

76.63

mean pLDDT

0.202

FRAUD score

96.6%

novelty (max id)

Per-domain breakdown

Source	Domain	Range	Residues	TM	RMSD Å	mean Cα Δ	Name
PAE	PAE:1-180	1-180	30	0.1519	4.832	4.235

All metrics

Global fold agreement

TM-score (norm. experiment)	0.7875
TM-score (norm. model)	0.1583
TM-score (norm. shorter)	0.7875
TM-score (norm. longer)	0.1583
Cα-RMSD (Å)	4.832
backbone-RMSD (Å)	4.704
all-atom-RMSD (Å)	5.3
core-RMSD (Å)	0.525
core fraction	0.533
GDT_TS	40.83
GDT_HA	17.5
MaxSub	0.261
structural overlap (3.5 Å)	0.4667

Local, superposition-free

lDDT	0.8275
contact-map Jaccard	1.0
contact precision	0.0
contact recall	0.0
distance-matrix mean Δ (Å)	1.43
CAD-score (approx)	0.8119

Backbone & secondary structure

SS agreement Q3 (%)	76.67
mean Δφ (°)	14.7
mean Δψ (°)	28.8
torsion within 30° (frac)	0.7
Rg experiment (Å)	12.95
Rg model (Å)	12.17
ΔRg (Å)	0.79

Confidence calibration

mean pLDDT	76.63
pLDDT↔lDDT Pearson	0.8935
pLDDT↔lDDT Spearman	0.8521
PAE↔observed Pearson	0.776
PAE overconfident frac	0.0
mean PAE (Å)	7.509
mean observed error (Å)	1.382

Context & headline

coverage of model	0.1667
coverage of experiment	1.0
seq identity aligned (%)	96.67
confidently-wrong residue frac	0.1667
FRAUD score	0.202

Deposited 2026-06-16 · released 2026-07-01 · EM · 2.64 Å · closest pre-cutoff chain: 1D0R_1