new PDB depositions vs. their blind AlphaFold predictions — a running test of "is folding solved?"

27TM_X

Metabotropic glutamate receptor 1 · Q13255 · RCSB 27TM · AF-Q13255-F1 (v6)

0.939
TM-score
0.9324
lDDT
5.387
Cα-RMSD Å
90.34
mean pLDDT
0.1359
FRAUD score
99.5%
novelty (max id)

Per-domain breakdown

SourceDomainRangeResiduesTMRMSD Åmean Cα ΔName
PAEPAE:1-11941-1194 7790.9388 5.3872.438

All metrics

Global fold agreement

TM-score (norm. experiment)0.939
TM-score (norm. model)0.623
TM-score (norm. shorter)0.939
TM-score (norm. longer)0.623
Cα-RMSD (Å)5.387
backbone-RMSD (Å)5.406
all-atom-RMSD (Å)5.292
core-RMSD (Å)1.126
core fraction0.478
GDT_TS60.78
GDT_HA35.88
MaxSub0.9537
structural overlap (3.5 Å)0.8935

Local, superposition-free

lDDT0.9324
contact-map Jaccard0.8496
contact precision0.9368
contact recall0.9012
distance-matrix mean Δ (Å)1.293
CAD-score (approx)0.8705

Backbone & secondary structure

SS agreement Q3 (%)89.47
mean Δφ (°)10.6
mean Δψ (°)12.1
torsion within 30° (frac)0.8947
Rg experiment (Å)53.91
Rg model (Å)54.36
ΔRg (Å)0.45

Confidence calibration

mean pLDDT90.34
pLDDT↔lDDT Pearson0.5965
pLDDT↔lDDT Spearman0.5614
PAE↔observed Pearson0.1432
PAE overconfident frac0.0025
mean PAE (Å)13.237
mean observed error (Å)1.291

Context & headline

coverage of model0.6524
coverage of experiment1.0
seq identity aligned (%)99.87
confidently-wrong residue frac0.0565
FRAUD score0.1359

Deposited 2026-06-11 · released 2026-06-24 · EM · 3.2 Å · closest pre-cutoff chain: 3KS9_1