new PDB depositions vs. their blind AlphaFold predictions — a running test of "is folding solved?"

26LK_A novel

Ribosomal biogenesis protein LAS1L · Q9Y4W2 · RCSB 26LK · AF-Q9Y4W2-F1 (v6)

0.693
TM-score
0.7679
lDDT
25.147
Cα-RMSD Å
71.4
mean pLDDT
0.64
FRAUD score
0.0%
novelty (max id)

Per-domain breakdown

SourceDomainRangeResiduesTMRMSD Åmean Cα ΔName
PAEPAE:1-7341-734 1860.0938 25.14722.449

All metrics

Global fold agreement

TM-score (norm. experiment)0.693
TM-score (norm. model)0.1956
TM-score (norm. shorter)0.693
TM-score (norm. longer)0.1956
Cα-RMSD (Å)25.147
backbone-RMSD (Å)25.05
all-atom-RMSD (Å)24.437
core-RMSD (Å)0.714
core fraction0.554
GDT_TS1.34
GDT_HA0.13
MaxSub0.0
structural overlap (3.5 Å)0.0

Local, superposition-free

lDDT0.7679
contact-map Jaccard0.6937
contact precision0.875
contact recall0.77
distance-matrix mean Δ (Å)11.393
CAD-score (approx)0.8307

Backbone & secondary structure

SS agreement Q3 (%)81.18
mean Δφ (°)18.5
mean Δψ (°)24.5
torsion within 30° (frac)0.6774
Rg experiment (Å)23.3
Rg model (Å)27.17
ΔRg (Å)3.87

Confidence calibration

mean pLDDT71.4
pLDDT↔lDDT Pearson0.8608
pLDDT↔lDDT Spearman0.7858
PAE↔observed Pearson0.7142
PAE overconfident frac0.1993
mean PAE (Å)13.998
mean observed error (Å)11.331

Context & headline

coverage of model0.2534
coverage of experiment0.9347
seq identity aligned (%)78.49
confidently-wrong residue frac0.6613
FRAUD score0.64

Deposited 2026-05-06 · released 2026-06-03 · EM · 3.4 Å · closest pre-cutoff chain: none