new PDB depositions vs. their blind AlphaFold predictions — a running test of "is folding solved?"

13IO_A novel

Essential MCU regulator, mitochondrial · Q9H4I9 · RCSB 13IO · AF-Q9H4I9-F1 (v6)

0.7969
TM-score
0.9348
lDDT
1.689
Cα-RMSD Å
84.41
mean pLDDT
0.0723
FRAUD score
0.0%
novelty (max id)

Per-domain breakdown

SourceDomainRangeResiduesTMRMSD Åmean Cα ΔName
PAEPAE:1-1071-107 530.7699 1.6891.357

All metrics

Global fold agreement

TM-score (norm. experiment)0.7969
TM-score (norm. model)0.4407
TM-score (norm. shorter)0.7969
TM-score (norm. longer)0.4407
Cα-RMSD (Å)1.689
backbone-RMSD (Å)1.763
all-atom-RMSD (Å)2.141
core-RMSD (Å)0.865
core fraction0.83
GDT_TS82.08
GDT_HA58.02
MaxSub0.7829
structural overlap (3.5 Å)0.9811

Local, superposition-free

lDDT0.9348
contact-map Jaccard0.875
contact precision1.0
contact recall0.875
distance-matrix mean Δ (Å)0.726
CAD-score (approx)0.8746

Backbone & secondary structure

SS agreement Q3 (%)98.11
mean Δφ (°)8.1
mean Δψ (°)12.9
torsion within 30° (frac)0.8679
Rg experiment (Å)23.78
Rg model (Å)23.64
ΔRg (Å)0.13

Confidence calibration

mean pLDDT84.41
pLDDT↔lDDT Pearson0.6085
pLDDT↔lDDT Spearman0.4873
PAE↔observed Pearson0.4063
PAE overconfident frac0.0
mean PAE (Å)9.629
mean observed error (Å)0.712

Context & headline

coverage of model0.4953
coverage of experiment1.0
seq identity aligned (%)100.0
confidently-wrong residue frac0.0
FRAUD score0.0723

Deposited 2026-05-07 · released 2026-07-08 · EM · 2.98 Å · closest pre-cutoff chain: none