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new PDB depositions vs. their blind AlphaFold predictions — a running test of "is folding solved?"

13GJ_A

IST1 homolog · P53990 · RCSB 13GJ · AF-P53990-F1 (v6)

0.968

TM-score

0.9747

lDDT

0.932

Cα-RMSD Å

94.33

mean pLDDT

0.052

FRAUD score

100.0%

novelty (max id)

Per-domain breakdown

Source	Domain	Range	Residues	TM	RMSD Å	mean Cα Δ	Name
PAE	PAE:1-364	1-364	183	0.968	0.932	0.834

All metrics

Global fold agreement

TM-score (norm. experiment)	0.968
TM-score (norm. model)	0.494
TM-score (norm. shorter)	0.968
TM-score (norm. longer)	0.494
Cα-RMSD (Å)	0.932
backbone-RMSD (Å)	0.935
all-atom-RMSD (Å)	1.428
core-RMSD (Å)	0.91
core fraction	0.989
GDT_TS	93.03
GDT_HA	73.63
MaxSub	0.968
structural overlap (3.5 Å)	1.0

Local, superposition-free

lDDT	0.9747
contact-map Jaccard	0.8299
contact precision	0.8703
contact recall	0.9471
distance-matrix mean Δ (Å)	0.311
CAD-score (approx)	0.2753

Backbone & secondary structure

SS agreement Q3 (%)	89.62
mean Δφ (°)	7.1
mean Δψ (°)	7.7
torsion within 30° (frac)	0.9727
Rg experiment (Å)	20.04
Rg model (Å)	19.96
ΔRg (Å)	0.09

Confidence calibration

mean pLDDT	94.33
pLDDT↔lDDT Pearson	0.5266
pLDDT↔lDDT Spearman	0.2818
PAE↔observed Pearson	0.2641
PAE overconfident frac	0.0
mean PAE (Å)	4.668
mean observed error (Å)	0.309

Context & headline

coverage of model	0.5027
coverage of experiment	1.0
seq identity aligned (%)	100.0
confidently-wrong residue frac	0.0
FRAUD score	0.052

Deposited 2026-05-05 · released 2026-07-08 · EM · 2.0 Å · closest pre-cutoff chain: 3FRR_1