new PDB depositions vs. their blind AlphaFold predictions — a running test of "is folding solved?"

13BV_D

Beclin-1 · Q14457 · RCSB 13BV · AF-Q14457-F1 (v6)

0.8016
TM-score
0.9213
lDDT
4.179
Cα-RMSD Å
88.73
mean pLDDT
0.2151
FRAUD score
100.0%
novelty (max id)

Per-domain breakdown

SourceDomainRangeResiduesTMRMSD Åmean Cα ΔName
PAEPAE:1-4501-450 3050.756 4.1793.687

All metrics

Global fold agreement

TM-score (norm. experiment)0.8016
TM-score (norm. model)0.5664
TM-score (norm. shorter)0.8016
TM-score (norm. longer)0.5664
Cα-RMSD (Å)4.179
backbone-RMSD (Å)4.137
all-atom-RMSD (Å)4.55
core-RMSD (Å)1.262
core fraction0.41
GDT_TS45.16
GDT_HA21.23
MaxSub0.8656
structural overlap (3.5 Å)0.5475

Local, superposition-free

lDDT0.9213
contact-map Jaccard0.815
contact precision0.8966
contact recall0.8997
distance-matrix mean Δ (Å)1.46
CAD-score (approx)0.8292

Backbone & secondary structure

SS agreement Q3 (%)89.51
mean Δφ (°)11.0
mean Δψ (°)15.2
torsion within 30° (frac)0.8328
Rg experiment (Å)65.17
Rg model (Å)66.09
ΔRg (Å)0.91

Confidence calibration

mean pLDDT88.73
pLDDT↔lDDT Pearson0.7103
pLDDT↔lDDT Spearman0.7202
PAE↔observed Pearson0.5518
PAE overconfident frac0.0
mean PAE (Å)14.23
mean observed error (Å)1.455

Context & headline

coverage of model0.6778
coverage of experiment1.0
seq identity aligned (%)100.0
confidently-wrong residue frac0.318
FRAUD score0.2151

Deposited 2026-04-28 · released 2026-05-13 · EM · 3.77 Å · closest pre-cutoff chain: 4DDP_1