new PDB depositions vs. their blind AlphaFold predictions — a running test of "is folding solved?"

13BV_B

Phosphatidylinositol 3-kinase catalytic subunit type 3 · Q8NEB9 · RCSB 13BV · AF-Q8NEB9-F1 (v6)

0.7996
TM-score
0.8806
lDDT
12.0
Cα-RMSD Å
82.89
mean pLDDT
0.3426
FRAUD score
100.0%
novelty (max id)

Per-domain breakdown

SourceDomainRangeResiduesTMRMSD Åmean Cα ΔName
PAEPAE:1-8871-887 2560.5174 12.08.17

All metrics

Global fold agreement

TM-score (norm. experiment)0.7996
TM-score (norm. model)0.2462
TM-score (norm. shorter)0.7996
TM-score (norm. longer)0.2462
Cα-RMSD (Å)12.0
backbone-RMSD (Å)11.979
all-atom-RMSD (Å)12.217
core-RMSD (Å)0.82
core fraction0.594
GDT_TS27.54
GDT_HA7.13
MaxSub0.8419
structural overlap (3.5 Å)0.1719

Local, superposition-free

lDDT0.8806
contact-map Jaccard0.8438
contact precision0.896
contact recall0.9353
distance-matrix mean Δ (Å)4.892
CAD-score (approx)0.8346

Backbone & secondary structure

SS agreement Q3 (%)87.11
mean Δφ (°)16.9
mean Δψ (°)20.9
torsion within 30° (frac)0.7578
Rg experiment (Å)24.88
Rg model (Å)20.66
ΔRg (Å)4.22

Confidence calibration

mean pLDDT82.89
pLDDT↔lDDT Pearson0.6466
pLDDT↔lDDT Spearman0.5214
PAE↔observed Pearson0.4988
PAE overconfident frac0.1265
mean PAE (Å)9.267
mean observed error (Å)4.873

Context & headline

coverage of model0.2886
coverage of experiment1.0
seq identity aligned (%)100.0
confidently-wrong residue frac0.6602
FRAUD score0.3426

Deposited 2026-04-28 · released 2026-05-13 · EM · 3.77 Å · closest pre-cutoff chain: 3LS8_1